DZ2389A1 - New farnesyl transferase inhibitors their preparation of the pharmaceutical compositions containing them and their use for the preparation of medicaments - Google Patents

New farnesyl transferase inhibitors their preparation of the pharmaceutical compositions containing them and their use for the preparation of medicaments

Info

Publication number
DZ2389A1
DZ2389A1 DZ970239A DZ970239A DZ2389A1 DZ 2389 A1 DZ2389 A1 DZ 2389A1 DZ 970239 A DZ970239 A DZ 970239A DZ 970239 A DZ970239 A DZ 970239A DZ 2389 A1 DZ2389 A1 DZ 2389A1
Authority
DZ
Algeria
Prior art keywords
preparation
medicaments
pharmaceutical compositions
compositions containing
transferase inhibitors
Prior art date
Application number
DZ970239A
Other languages
French (fr)
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Application granted granted Critical
Publication of DZ2389A1 publication Critical patent/DZ2389A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/724,7-Endo-alkylene-iso-indoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DZ970239A 1996-12-30 1997-12-27 New farnesyl transferase inhibitors their preparation of the pharmaceutical compositions containing them and their use for the preparation of medicaments DZ2389A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9616206A FR2757855B1 (en) 1996-12-30 1996-12-30 NOVEL FARNESYL TRANSFERASE INHIBITORS, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Publications (1)

Publication Number Publication Date
DZ2389A1 true DZ2389A1 (en) 2002-12-28

Family

ID=9499293

Family Applications (1)

Application Number Title Priority Date Filing Date
DZ970239A DZ2389A1 (en) 1996-12-30 1997-12-27 New farnesyl transferase inhibitors their preparation of the pharmaceutical compositions containing them and their use for the preparation of medicaments

Country Status (32)

Country Link
EP (1) EP0948483B1 (en)
JP (1) JP2001509147A (en)
KR (1) KR20000062391A (en)
AR (1) AR008950A1 (en)
AT (1) ATE214367T1 (en)
AU (1) AU741921B2 (en)
BR (1) BR9714498A (en)
CA (1) CA2275943A1 (en)
CO (1) CO4920252A1 (en)
CZ (1) CZ233599A3 (en)
DE (1) DE69711081T2 (en)
DK (1) DK0948483T3 (en)
DZ (1) DZ2389A1 (en)
EA (1) EA002114B1 (en)
ES (1) ES2172033T3 (en)
FR (1) FR2757855B1 (en)
HU (1) HUP0001747A3 (en)
ID (1) ID22922A (en)
IL (1) IL130453A0 (en)
MA (1) MA26460A1 (en)
NO (1) NO993225L (en)
NZ (1) NZ336042A (en)
PE (1) PE28199A1 (en)
PL (1) PL334345A1 (en)
PT (1) PT948483E (en)
SK (1) SK88399A3 (en)
TN (1) TNSN97214A1 (en)
TR (1) TR199901502T2 (en)
UY (1) UY24832A1 (en)
WO (1) WO1998029390A1 (en)
YU (1) YU30299A (en)
ZA (1) ZA9711734B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2787327B1 (en) * 1998-12-21 2003-01-17 Aventis Pharma Sa COMPOSITIONS CONTAINING FARNESYL TRANSFERASE INHIBITORS
FR2796640A1 (en) * 1999-07-22 2001-01-26 Aventis Pharma Sa New 3,9-ethano-2,3,3a,4,9,9a-hexahydro-1H-benzo (f) isoindole derivatives, are farnesyl transferase inhibitors useful for treating hyperproliferative disorders, e.g. psoriasis, restenosis or especially cancer
FR2796641B1 (en) * 1999-07-22 2001-09-21 Aventis Pharma Sa NOVEL PROCESS FOR THE PREPARATION OF BENZOPERHYDROISOINDOLE COMPOUNDS
FR2845994B1 (en) * 2002-10-18 2006-05-19 Servier Lab NOVEL SUBSTITUTED BENZO [E] [1,4] OXAZINO [3,2-G] ISOINDOLE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
WO2005089504A2 (en) * 2004-03-18 2005-09-29 The Brigham And Women's Hospital, Inc. Methods for the treatment of synucleinopathies

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0730605A1 (en) * 1993-11-05 1996-09-11 Warner-Lambert Company Substituted di- and tripeptide inhibitors of protein:farnesyl transferase
FR2736641B1 (en) * 1995-07-10 1997-08-22 Rhone Poulenc Rorer Sa NOVEL FARNESYL TRANSFERASE INHIBITORS, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
EA199900608A1 (en) 2000-02-28
BR9714498A (en) 2000-03-21
UY24832A1 (en) 2001-08-27
ATE214367T1 (en) 2002-03-15
TNSN97214A1 (en) 2005-03-15
DE69711081D1 (en) 2002-04-18
SK88399A3 (en) 2000-05-16
NZ336042A (en) 2000-12-22
EP0948483A1 (en) 1999-10-13
CO4920252A1 (en) 2000-05-29
EP0948483B1 (en) 2002-03-13
PL334345A1 (en) 2000-02-28
NO993225D0 (en) 1999-06-29
ID22922A (en) 1999-12-16
WO1998029390A1 (en) 1998-07-09
DK0948483T3 (en) 2002-07-01
YU30299A (en) 2002-03-18
HUP0001747A2 (en) 2000-09-28
FR2757855A1 (en) 1998-07-03
JP2001509147A (en) 2001-07-10
KR20000062391A (en) 2000-10-25
FR2757855B1 (en) 1999-01-29
ZA9711734B (en) 1998-06-25
HUP0001747A3 (en) 2000-10-30
TR199901502T2 (en) 1999-09-21
EA002114B1 (en) 2001-12-24
AR008950A1 (en) 2000-02-23
MA26460A1 (en) 2004-12-20
ES2172033T3 (en) 2002-09-16
PT948483E (en) 2002-08-30
AU5669498A (en) 1998-07-31
PE28199A1 (en) 1999-06-05
CZ233599A3 (en) 1999-09-15
CA2275943A1 (en) 1998-07-09
DE69711081T2 (en) 2002-08-01
AU741921B2 (en) 2001-12-13
NO993225L (en) 1999-08-24
IL130453A0 (en) 2000-06-01

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