FR2762318B1 - Compositions presentant une liberation prolongee et leur procede de preparation - Google Patents

Compositions presentant une liberation prolongee et leur procede de preparation

Info

Publication number
FR2762318B1
FR2762318B1 FR9704837A FR9704837A FR2762318B1 FR 2762318 B1 FR2762318 B1 FR 2762318B1 FR 9704837 A FR9704837 A FR 9704837A FR 9704837 A FR9704837 A FR 9704837A FR 2762318 B1 FR2762318 B1 FR 2762318B1
Authority
FR
France
Prior art keywords
compositions
preparation
sustained release
sustained
release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9704837A
Other languages
English (en)
Other versions
FR2762318A1 (fr
Inventor
Marc Pellet
Chantal Roume
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharma Biotech
Original Assignee
Pharma Biotech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharma Biotech filed Critical Pharma Biotech
Priority to FR9704837A priority Critical patent/FR2762318B1/fr
Priority to ARP980101756A priority patent/AR012448A1/es
Priority to MYPI98001698A priority patent/MY118835A/en
Priority to TW087105802A priority patent/TW577759B/zh
Priority to ZA983205A priority patent/ZA983205B/xx
Priority to AT98921551T priority patent/ATE389388T1/de
Priority to CNB031545998A priority patent/CN1313082C/zh
Priority to BR9808933-1A priority patent/BR9808933A/pt
Priority to AU74363/98A priority patent/AU741964B2/en
Priority to CNB988052202A priority patent/CN1144584C/zh
Priority to HU0004297A priority patent/HUP0004297A2/hu
Priority to DE69839264T priority patent/DE69839264T2/de
Priority to CZ0362699A priority patent/CZ297078B6/cs
Priority to ES98921551T priority patent/ES2303353T3/es
Priority to RU99124209/14A priority patent/RU2198678C2/ru
Priority to EP98921551A priority patent/EP0980240B1/fr
Priority to PL336296A priority patent/PL196771B1/pl
Priority to IL13221798A priority patent/IL132217A/en
Priority to PT98921551T priority patent/PT980240E/pt
Priority to CA2286575A priority patent/CA2286575C/fr
Priority to DK98921551T priority patent/DK0980240T3/da
Priority to US09/403,058 priority patent/US6217893B1/en
Priority to JP54515098A priority patent/JP4557312B2/ja
Priority to PCT/FR1998/000773 priority patent/WO1998047489A1/fr
Publication of FR2762318A1 publication Critical patent/FR2762318A1/fr
Application granted granted Critical
Publication of FR2762318B1 publication Critical patent/FR2762318B1/fr
Priority to NO19995063A priority patent/NO327999B1/no
Priority to US09/707,372 priority patent/US6475507B1/en
Priority to HK00107498A priority patent/HK1027983A1/xx
Priority to ARP070102999A priority patent/AR061828A2/es
Priority to NO20080803A priority patent/NO20080803L/no
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Reproductive Health (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR9704837A 1997-04-18 1997-04-18 Compositions presentant une liberation prolongee et leur procede de preparation Expired - Lifetime FR2762318B1 (fr)

Priority Applications (29)

Application Number Priority Date Filing Date Title
FR9704837A FR2762318B1 (fr) 1997-04-18 1997-04-18 Compositions presentant une liberation prolongee et leur procede de preparation
MYPI98001698A MY118835A (en) 1997-04-18 1998-04-16 Sustained release compositions and the process for their preparation
TW087105802A TW577759B (en) 1997-04-18 1998-04-16 Sustained release compositions in the form of microcapsules or implants and the process for their preparation
ZA983205A ZA983205B (en) 1997-04-18 1998-04-16 Sustained release compositions and the process for their preparation
ARP980101756A AR012448A1 (es) 1997-04-18 1998-04-16 Composicion en forma de microcapsulas o de implantes que comprende un excipiente biodegradable, polimero o co-polimero, o una mezcla de talesexcipientes, y una sustancia activa o una mezcla de sustancias activas, procedimiento para la preparacion de una sustancia soluble en agua de elevada
DK98921551T DK0980240T3 (da) 1997-04-18 1998-04-17 Sammensætninger med lang frigivelse og fremgangsmåde til fremstilling heraf
BR9808933-1A BR9808933A (pt) 1997-04-18 1998-04-17 Composição sob forma de microcápsulas ou de implantes, processo de preparação de uma substância hidrossolúvel, substância ativa, acetato de triptorelina, acetato de lanreotìdeo, ou acetato de octreotìdeo, e rna de filamento duplo
AU74363/98A AU741964B2 (en) 1997-04-18 1998-04-17 Sustained-release compositions and method for preparing same
CNB988052202A CN1144584C (zh) 1997-04-18 1998-04-17 缓释组合物及其制备方法
HU0004297A HUP0004297A2 (hu) 1997-04-18 1998-04-17 Nyújtott felszabadulású készítmények és eljárás előállításukra
DE69839264T DE69839264T2 (de) 1997-04-18 1998-04-17 Zusammensetzungen mit verzoegerter freisetzung und verfahren zu deren herstellung
CZ0362699A CZ297078B6 (cs) 1997-04-18 1998-04-17 Prostredek ve forme mikrokapslí nebo implantátu
ES98921551T ES2303353T3 (es) 1997-04-18 1998-04-17 Composiciones que presentan una liberacion prolongada y su procedimiento de preparacion.
RU99124209/14A RU2198678C2 (ru) 1997-04-18 1998-04-17 Композиции пролонгированного высвобождения и способ их получения
AT98921551T ATE389388T1 (de) 1997-04-18 1998-04-17 Zusammensetzungen mit verzoegerter freisetzung und verfahren zu deren herstellung
PL336296A PL196771B1 (pl) 1997-04-18 1998-04-17 Kompozycja w postaci mikrokapsułek albo implantów o przedłużonym uwalnianiu substancji czynnej
IL13221798A IL132217A (en) 1997-04-18 1998-04-17 Substained-release compositions and method for preparing same
PT98921551T PT980240E (pt) 1997-04-18 1998-04-17 Composições apresentando uma libertação prolongada e seu processo de preparação
CA2286575A CA2286575C (fr) 1997-04-18 1998-04-17 Compositions presentant une liberation prolongee et leur procede de preparation
CNB031545998A CN1313082C (zh) 1997-04-18 1998-04-17 缓释组合物及其制备方法
US09/403,058 US6217893B1 (en) 1997-04-18 1998-04-17 Sustained-release compositions and method for preparing same
JP54515098A JP4557312B2 (ja) 1997-04-18 1998-04-17 徐放性組成物及びその製造方法
PCT/FR1998/000773 WO1998047489A1 (fr) 1997-04-18 1998-04-17 Compositions presentant une liberation prolongee et leur procede de preparation
EP98921551A EP0980240B1 (fr) 1997-04-18 1998-04-17 Compositions presentant une liberation prolongee et leur procede de preparation
NO19995063A NO327999B1 (no) 1997-04-18 1999-10-15 Preparater med forsinket frigjoring
US09/707,372 US6475507B1 (en) 1997-04-18 2000-11-06 Sustained release compositions and the process for their preparation
HK00107498A HK1027983A1 (en) 1997-04-18 2000-11-23 Sustained-release compositions and method for preparing same.
ARP070102999A AR061828A2 (es) 1997-04-18 2007-07-05 Procedimiento para la preparacion de una sustancia soluble en agua de elevada area superficial especifica
NO20080803A NO20080803L (no) 1997-04-18 2008-02-14 Preparater med forsinket frigjoring og fremgangsmaten for deres fremstilling

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9704837A FR2762318B1 (fr) 1997-04-18 1997-04-18 Compositions presentant une liberation prolongee et leur procede de preparation

Publications (2)

Publication Number Publication Date
FR2762318A1 FR2762318A1 (fr) 1998-10-23
FR2762318B1 true FR2762318B1 (fr) 1999-09-17

Family

ID=9506092

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9704837A Expired - Lifetime FR2762318B1 (fr) 1997-04-18 1997-04-18 Compositions presentant une liberation prolongee et leur procede de preparation

Country Status (2)

Country Link
FR (1) FR2762318B1 (fr)
ZA (1) ZA983205B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8541028B2 (en) 2004-08-04 2013-09-24 Evonik Corporation Methods for manufacturing delivery devices and devices thereof

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT202000017191A1 (it) * 2020-07-15 2022-01-15 Xbrane Biopharma Ab Procedimento senza acqua per preparare una composizione farmaceutica per un rilascio più prolungato e controllato di triptorelina o di un suo sale

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH661206A5 (fr) * 1983-09-23 1987-07-15 Debiopharm Sa Procede pour la preparation d'un medicament destine au traitement de maladies hormonodependantes.
US5021554A (en) * 1989-02-24 1991-06-04 Eli Lilly And Company Process for protein particle size reduction using a fluid-energy mill
GB2246514B (en) * 1990-08-01 1993-12-15 Scras Sustained release pharmaceutical compositions and the preparation of particles for use therein
DE4041563A1 (de) * 1990-12-22 1992-06-25 Sanol Arznei Schwarz Gmbh Verfahren zur herstellung wirkstoffhaltiger mikropartikel aus hydrolytisch abbaubaren polymeren
DE4223169C1 (de) * 1992-07-10 1993-11-25 Ferring Arzneimittel Gmbh Verfahren zur Mikroverkapselung wasserlöslicher Wirkstoffe
FR2693905B1 (fr) * 1992-07-27 1994-09-02 Rhone Merieux Procédé de préparation de microsphères pour la libération prolongée de l'hormone LHRH et ses analogues, microsphères et formulations obtenues.
US6117455A (en) * 1994-09-30 2000-09-12 Takeda Chemical Industries, Ltd. Sustained-release microcapsule of amorphous water-soluble pharmaceutical active agent

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8541028B2 (en) 2004-08-04 2013-09-24 Evonik Corporation Methods for manufacturing delivery devices and devices thereof

Also Published As

Publication number Publication date
ZA983205B (en) 1998-10-19
FR2762318A1 (fr) 1998-10-23

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