FR2755146B1 - Procede de pontage selectif et irreversible d'oligonucleotides platines sur de l'arn et ses applications - Google Patents

Procede de pontage selectif et irreversible d'oligonucleotides platines sur de l'arn et ses applications

Info

Publication number
FR2755146B1
FR2755146B1 FR9613129A FR9613129A FR2755146B1 FR 2755146 B1 FR2755146 B1 FR 2755146B1 FR 9613129 A FR9613129 A FR 9613129A FR 9613129 A FR9613129 A FR 9613129A FR 2755146 B1 FR2755146 B1 FR 2755146B1
Authority
FR
France
Prior art keywords
oligonucleotides
rna
platinum
selective
applications
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9613129A
Other languages
English (en)
Other versions
FR2755146A1 (fr
Inventor
Marc Leng
Rozenn Aude Helene Dalbies
Marc Nicolas Pierr Boudvillain
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR9613129A priority Critical patent/FR2755146B1/fr
Priority to PCT/FR1997/001924 priority patent/WO1998018915A2/fr
Publication of FR2755146A1 publication Critical patent/FR2755146A1/fr
Application granted granted Critical
Publication of FR2755146B1 publication Critical patent/FR2755146B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/32Chemical structure of the sugar
    • C12N2310/3212'-O-R Modification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/35Nature of the modification
    • C12N2310/351Conjugate
    • C12N2310/3511Conjugate intercalating or cleaving agent

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
FR9613129A 1996-10-28 1996-10-28 Procede de pontage selectif et irreversible d'oligonucleotides platines sur de l'arn et ses applications Expired - Fee Related FR2755146B1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR9613129A FR2755146B1 (fr) 1996-10-28 1996-10-28 Procede de pontage selectif et irreversible d'oligonucleotides platines sur de l'arn et ses applications
PCT/FR1997/001924 WO1998018915A2 (fr) 1996-10-28 1997-10-27 Procede de pontage selectif et irreversible d'oligonucleotides platines sur de l'arn et ses applications

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9613129A FR2755146B1 (fr) 1996-10-28 1996-10-28 Procede de pontage selectif et irreversible d'oligonucleotides platines sur de l'arn et ses applications

Publications (2)

Publication Number Publication Date
FR2755146A1 FR2755146A1 (fr) 1998-04-30
FR2755146B1 true FR2755146B1 (fr) 1998-12-04

Family

ID=9497100

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9613129A Expired - Fee Related FR2755146B1 (fr) 1996-10-28 1996-10-28 Procede de pontage selectif et irreversible d'oligonucleotides platines sur de l'arn et ses applications

Country Status (2)

Country Link
FR (1) FR2755146B1 (fr)
WO (1) WO1998018915A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6113934A (en) * 1998-06-11 2000-09-05 Virginia Commonwealth University Platinum complexes with anti-viral activity and method of using same
EP1006199A1 (fr) * 1998-12-03 2000-06-07 Kreatech Biotechnology B.V. Procédé pour la production des réticulations à des points sélectionnés entre les brins d'acides nucléiques et leur utilisation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4777129A (en) * 1983-12-12 1988-10-11 Molecular Diagnostics, Inc. Nucleic acid probe detectable by specific nucleic acid binding protein
NL9001639A (nl) * 1990-07-19 1992-02-17 Amc Amsterdam Pt-houdende verbinding, werkwijze voor de bereiding ervan, alsmede toepassing van dergelijke verbindingen.

Also Published As

Publication number Publication date
FR2755146A1 (fr) 1998-04-30
WO1998018915A2 (fr) 1998-05-07

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Legal Events

Date Code Title Description
ST Notification of lapse