FR2735331A1 - Premix for young stock animals - Google Patents

Premix for young stock animals Download PDF

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Publication number
FR2735331A1
FR2735331A1 FR9507532A FR9507532A FR2735331A1 FR 2735331 A1 FR2735331 A1 FR 2735331A1 FR 9507532 A FR9507532 A FR 9507532A FR 9507532 A FR9507532 A FR 9507532A FR 2735331 A1 FR2735331 A1 FR 2735331A1
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Prior art keywords
liter
complex
support
content
bile salts
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FR9507532A
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French (fr)
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MANIA VENANCE
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MANIA VENANCE
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Priority to FR9507532A priority Critical patent/FR2735331A1/en
Publication of FR2735331A1 publication Critical patent/FR2735331A1/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/142Amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/105Aliphatic or alicyclic compounds

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A nutritional premix comprises: (a) an acidifier; and (b) 2 cpds. to assist the synthesis of biliary salts and ensure the emulsification of fats.

Description

Demande de Brevet d'invention
Description
La présente invention concerne un complexe nutritionnel destiné à améliorer la digestibilité des nutriments chez les jeunes animaux d'élevage, au stade monogastrique.
Patent Application
Description
The present invention relates to a nutritional complex intended to improve the digestibility of nutrients in young farm animals, in the monogastric stage.

il est fréquent de rencontrer des troubles digestifs chez les animaux, provoqués par une mauvaise activité des lipases ou des protéases. Ces troubles digestifs se traduisent souvent par des diarrhées dites blanches , qui nécessitent souvent une antibiothérapie, coûteuse du point de vue financier, mais aussi du point de vue de l'hygiène. Ces diarrhées entraînent des mortalités plus ou moins importantes dans les élevages.it is common to encounter digestive disorders in animals, caused by poor lipase or protease activity. These digestive disorders often result in so-called white diarrhea, which often requires antibiotic therapy, costly from a financial point of view, but also from a hygiene point of view. These diarrheas cause more or less significant mortalities on farms.

Le but du complexe nutritionnel présent est d'optimiser ces activités enymatiques, en leur préparant un terrain plus favorable. En effet, la composition de ce complexe est telle que les mécanismes de la digestion sont amplement facilités.The purpose of the present nutritional complex is to optimize these enymatic activities, by preparing them more favorable ground. Indeed, the composition of this complex is such that the mechanisms of digestion are greatly facilitated.

Les protéines peuvent parfois présenter une conformation ou une structure chimique peu favorable à leur destruction enzymatique. 1l convient donc de dénaturer ces protéines par une acidification lactique, en portant dans le complexe une quantité d'acide lactique comprise entre igIlitre ou /kg de complexe sur son support. Cet acide lactique assurera la destruction de la conformation native des protéines, en particulier des protéines phosphorylées comme la caséine du lait.Proteins can sometimes have a conformation or a chemical structure unfavorable to their enzymatic destruction. It is therefore advisable to denature these proteins by lactic acidification, by carrying in the complex an amount of lactic acid between igIlitre or / kg of complex on its support. This lactic acid will ensure the destruction of the native conformation of proteins, in particular phosphorylated proteins such as milk casein.

Cette dénaturation permet l'accès aux sites spécifiques de l'action de la pepsine, de la trypsine et de la chymotlypsine. L'action enzymatique des autres protéases (caiboxypeptidase, aminopeptidase) peut alors parachever la destruction de la structure primaire des protéines à digérer, aboutissant aux acides aminés libres qui traverseront la barrière intestinale, évitant à la flore intestinale de trouver les substrats d'une activité de type fermentaire, précisément à l'origine des diarrhées blanches .This denaturation allows access to specific sites of the action of pepsin, trypsin and chymotlypsin. The enzymatic action of the other proteases (caiboxypeptidase, aminopeptidase) can then complete the destruction of the primary structure of the proteins to be digested, leading to free amino acids which will cross the intestinal barrier, preventing the intestinal flora from finding the substrates for activity. of the fermentative type, precisely at the origin of white diarrhea.

Cette seule acidification n'est pas suffisante pour limiter le risque de diarrhées blanches ; si la prise en charge des matières grasses par la bordure en brosse de l'intestin est défaillante, pour cause d'une insuffisance d'émulsification,
I'accumulation des lipides dans la lumière intestinale peut nuire aux activités enzymatiques diverses, notamment celles des protéases évoquées plus haut.
This acidification alone is not sufficient to limit the risk of white diarrhea; if the management of fat by the brush border of the intestine is faulty, due to insufficient emulsification,
The accumulation of lipids in the intestinal lumen can impair various enzymatic activities, in particular those of the proteases mentioned above.

De plus, cette mauvaise assimilation des lipides maintient l'effet de réplétion qui entraine des pertes d'appétit, donc un affaiblissement général de l'organisme, avec toutes les conséquences imaginables sur le plan infectieux. In addition, this poor assimilation of lipids maintains the repletion effect which leads to loss of appetite, therefore a general weakening of the organism, with all the imaginable consequences on the infectious level.

Pour lever ce risque d'accumulation des matières grasses alimentaires. il convient donc d'accentuer l'émulsification. en augmentant la synthèse des sels biliaires.To remove this risk of accumulation of food fats. emulsification should therefore be accentuated. by increasing the synthesis of bile salts.

L'addition des précurseurs de ces sels biliaires. notamment la taurine (acide taurocholique), et le glycocolle (acide glycocholique), dans des teneurs comprises chacune entre lgilitre ou 'g et 100g/litre ou ikg de complexe sur son support, contribue très fortement à activer cette fonction hépatique.On diminue ainsi le risque de surcharge lipidique dans l intestin. c'est à dire, on optimise ainsi l'émulsilication des matières grasses en vue de la formation des micelles lipidiques. qui seront prises en charge par la bordure en brosse.The addition of the precursors of these bile salts. in particular taurine (taurocholic acid), and glycocolle (glycocholic acid), in contents each between lgilitre or 'g and 100g / liter or ikg of complex on its support, contributes very strongly to activate this hepatic function. the risk of lipid overload in the intestine. that is to say, it optimizes the emulsification of fat for the formation of lipid micelles. which will be supported by the brush border.

Tous ces mécanismes énumérés se font grâce à un renfort énergétique. 11 est indispensable, pour assurer la réussite d'un tel principe, de l'accompagner de facteurs favorisant la fourniture d'énergie. L'addition de carnitine. dans une teneur comprise entre lg/litre ou kg et 100g/litre ou ikg- de complexe sur son support favorise le transfert des matières grasses intracellulaires sur leur site de combustion. qui est la mitochondrie. Cette combustion intramitochondriale fournit donc l'énergie nécessaire. au moment meme où les cellules de l'appareil digestif en ont le plus besoin.All of these mechanisms listed are made through an energy boost. To ensure the success of such a principle, it is essential to accompany it with factors favoring the supply of energy. Addition of carnitine. in a content of between lg / liter or kg and 100g / liter or ikg- of complex on its support promotes the transfer of intracellular fats to their combustion site. which is the mitochondrion. This intramitochondrial combustion therefore provides the necessary energy. at the very moment when the cells of the digestive system need it most.

Le complexe nutritionnel peut se présenter sous forme d'un mélange de poudre que l'on ajoutera à l'aliment en cours de fabrication, ou bien que l'éleveur peut additionner à l'aliment avant de le distribuer à ses animaux mais ce complexe est aussi sous forme liquide, utilisable directement en élevage. The nutritional complex may be in the form of a powder mixture which will be added to the feed during manufacture, or that the breeder may add to the feed before distributing it to his animals, but this complex is also in liquid form, usable directly in breeding.

Claims (2)

REVENDICATIONS 1 - Premix nutritionnel destiné à optimiser la digestion des protéines et des lipides du repas chez les animaux jeunes au stade monogastrique caractérisé en ce qu'il contiens à la fois:1 - Nutritional premix intended to optimize the digestion of the proteins and lipids of the meal in young animals at the monogastric stage characterized in that it contains both: a - un produit acidifiant, pour assurer la dénaturation des protéines; a - an acidifying product, to ensure the denaturation of proteins; b - deux constituants destinés à favoriser la synthèse dc sels biliaires, b - two constituents intended to promote the synthesis of bile salts, Icsquels garantiront l'émulsification des graisses, en en vue de leur prise en Which will guarantee the emulsification of fats, with a view to their taking charge optimale par la bordure en brosse. optimal load by the brush border. 2 - Premix nutritionnel selon la revendication (1), caractérisé en ce qu'il comporte une substance d'optimisation de la couverture énergétique dans le métabolisme digestif; 3 - Premix nutritionnel selon les revendications (1) et (2), caractérisé en ce qu'il comporte les constituants de la nature suivante:2 - Nutritional premix according to claim (1), characterized in that it comprises a substance for optimizing the energy coverage in the digestive metabolism; 3 - Nutritional premix according to claims (1) and (2), characterized in that it comprises the constituents of the following nature: (1) a - Produit acidifiant; : acide lactique, dans une teneur variant entre lg/litre ou n et 100g/litre ou /kg de complexe sur son support' (1) a - Acidifying product; : lactic acid, in a content varying between lg / liter or n and 100g / liter or / kg of complex on its support ' (1) b - Un précurseur de sels biliaires la taurine, dans une teneur comprise entre lg/litre ou/kg et 100g/litre ou /kg de complexe sur son support; (1) b - A precursor of bile salts, taurine, in a content of between lg / liter or / kg and 100g / liter or / kg of complex on its support; (1) c - Un précurseur de sels biliaires : le glycocolle, dans une teneur comprise entre lg/litre ou/kg et 100g/litre ou /kg de complexe sur son support; (1) c - A precursor of bile salts: glycocolle, in a content of between lg / liter or / kg and 100g / liter or / kg of complex on its support; (2) d - Un facteur de la couverture énergétique de la mitochondrie : la camitinc, dans une teneur comprise entre lg/litre ou Xkg el 100g/litre ou Jkg de complexe sur son support  (2) d - A factor in the energy coverage of the mitochondria: camitinc, in a content of between lg / liter or Xkg and 100g / liter or Jkg of complex on its support
FR9507532A 1995-06-19 1995-06-19 Premix for young stock animals Pending FR2735331A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR9507532A FR2735331A1 (en) 1995-06-19 1995-06-19 Premix for young stock animals

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Application Number Priority Date Filing Date Title
FR9507532A FR2735331A1 (en) 1995-06-19 1995-06-19 Premix for young stock animals

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FR2735331A1 true FR2735331A1 (en) 1996-12-20

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000000039A1 (en) * 1998-06-26 2000-01-06 The Iams Company Process and product for promoting weight loss in overweight dogs
EP0972451A1 (en) * 1998-07-14 2000-01-19 MFE Marienfelde GmbH Unternehmen für Ernährung Oil-containing feed composition
US6630159B2 (en) 1999-02-23 2003-10-07 The Procter & Gamble Company Limiting weight gain of cats by feeding carbohydrate source that excludes rice
US7001618B1 (en) 1999-07-09 2006-02-21 The Iams Company Nutritional composition for weight management
US11547125B2 (en) 2015-02-13 2023-01-10 Mars, Incorporated Pet food feeding system

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000000039A1 (en) * 1998-06-26 2000-01-06 The Iams Company Process and product for promoting weight loss in overweight dogs
US6204291B1 (en) 1998-06-26 2001-03-20 The Iams Company Process for promoting weight loss in overweight dogs
EP0972451A1 (en) * 1998-07-14 2000-01-19 MFE Marienfelde GmbH Unternehmen für Ernährung Oil-containing feed composition
US6630159B2 (en) 1999-02-23 2003-10-07 The Procter & Gamble Company Limiting weight gain of cats by feeding carbohydrate source that excludes rice
US7001618B1 (en) 1999-07-09 2006-02-21 The Iams Company Nutritional composition for weight management
US11547125B2 (en) 2015-02-13 2023-01-10 Mars, Incorporated Pet food feeding system

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