FR2731355B1 - NOVEL IMMUNOGENS, NOVEL ANTIBODIES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Google Patents

NOVEL IMMUNOGENS, NOVEL ANTIBODIES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Info

Publication number
FR2731355B1
FR2731355B1 FR9502708A FR9502708A FR2731355B1 FR 2731355 B1 FR2731355 B1 FR 2731355B1 FR 9502708 A FR9502708 A FR 9502708A FR 9502708 A FR9502708 A FR 9502708A FR 2731355 B1 FR2731355 B1 FR 2731355B1
Authority
FR
France
Prior art keywords
novel
preparation
pharmaceutical compositions
compositions containing
immunogens
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9502708A
Other languages
French (fr)
Other versions
FR2731355A1 (en
Inventor
Jean Francois Zagury
Bernard Bizzini
Daniel Zagury
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neovacs SA
Original Assignee
Neovacs SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9502708A priority Critical patent/FR2731355B1/en
Application filed by Neovacs SA filed Critical Neovacs SA
Priority to PL96322143A priority patent/PL322143A1/en
Priority to AT96906795T priority patent/ATE196255T1/en
Priority to DK96906795T priority patent/DK0814834T4/en
Priority to AU50071/96A priority patent/AU710626B2/en
Priority to ES96906795T priority patent/ES2150107T5/en
Priority to CA2215483A priority patent/CA2215483C/en
Priority to PCT/FR1996/000357 priority patent/WO1996027389A1/en
Priority to KR1019970706241A priority patent/KR100309856B1/en
Priority to US08/913,221 priority patent/US6132721A/en
Priority to DE69610295T priority patent/DE69610295T3/en
Priority to JP8526669A priority patent/JPH11501310A/en
Priority to CNB961931914A priority patent/CN1226046C/en
Priority to EP96906795A priority patent/EP0814834B2/en
Priority to PT96906795T priority patent/PT814834E/en
Priority to BR9607659A priority patent/BR9607659A/en
Publication of FR2731355A1 publication Critical patent/FR2731355A1/en
Publication of FR2731355B1 publication Critical patent/FR2731355B1/en
Application granted granted Critical
Priority to OA70071A priority patent/OA10615A/en
Priority to GR20000402673T priority patent/GR3034970T3/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/21—Retroviridae, e.g. equine infectious anemia virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1072—Regulatory proteins, e.g. tat, rev, vpt
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
    • C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/826—Viruses
FR9502708A 1995-03-08 1995-03-08 NOVEL IMMUNOGENS, NOVEL ANTIBODIES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Expired - Fee Related FR2731355B1 (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
FR9502708A FR2731355B1 (en) 1995-03-08 1995-03-08 NOVEL IMMUNOGENS, NOVEL ANTIBODIES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
CNB961931914A CN1226046C (en) 1995-03-08 1996-03-07 Non-toxic immunogens derived from a retroviral regulatory protein, antibodies, preparation mthod therefor and pharmaceutical compositions containing same
AT96906795T ATE196255T1 (en) 1995-03-08 1996-03-07 DETOXIFIED IMMUNOGENIC ANTIBODIES DIRECTED AGAINST A RETROVIRAL REGULATORY PROTEIN, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE IMMUNOGENE OR ANTIBODIES.
AU50071/96A AU710626B2 (en) 1995-03-08 1996-03-07 Non-toxic immunogens derived from a retroviral regulatory protein, antibodies, preparation process and pharmaceutical compositions comprising them
ES96906795T ES2150107T5 (en) 1995-03-08 1996-03-07 NON-TOXIC IMMUNOGENS THAT COME FROM A RETROVIRAL REGULATION PROTEIN, ANTIBODIES DIRECTED AGAINST THESE IMMUNOGENS, PROCEDURE FOR THE PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
CA2215483A CA2215483C (en) 1995-03-08 1996-03-07 Non-toxic immunogens derived from a retroviral regulatory protein, antibodies, preparation method therefor, and pharmaceutical compositions containing same
PCT/FR1996/000357 WO1996027389A1 (en) 1995-03-08 1996-03-07 Non-toxic immunogens derived from a retroviral regulatory protein, antibodies, preparation method therefor, and pharmaceutical compositions containing same
KR1019970706241A KR100309856B1 (en) 1995-03-08 1996-03-07 Non-toxic immunogens derived from retroviral regulatory proteins, antibodies, methods for their preparation, and pharmaceutical compositions containing them
EP96906795A EP0814834B2 (en) 1995-03-08 1996-03-07 Non-toxic immunogens derived from a retroviral regulatory protein, antibodies directed against said immunogens, preparation method therefor, and pharmaceutical compositions containing the same
DE69610295T DE69610295T3 (en) 1995-03-08 1996-03-07 PHARMACEUTICAL COMPOSITIONS DERIVED FROM A RETROVIRAL REGULATORY PROTEIN, DETOXIFIED IMMUNOGENS, ANTIBODIES PROVIDED THEREFOR, METHODS FOR THE PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH IMMUNOGENS OR ANTIBODIES.
PL96322143A PL322143A1 (en) 1995-03-08 1996-03-07 Non-topxic immunogenes originating frommretroviral regulator protein, antibodies as such, method of preparing them and pharmaceutic compositions containing them
DK96906795T DK0814834T4 (en) 1995-03-08 1996-03-07 Immunogens devoid of toxicity derived from a retroviral regulatory protein, antibodies directed against these immunogens, methods of their preparation, and pharmaceutical compositions containing them
US08/913,221 US6132721A (en) 1995-03-08 1996-03-07 Non-Toxic immunogens derived from a retroviral regulatory protein, antibodies, preparation method therefor, and pharmaceutical compositions containing same
PT96906795T PT814834E (en) 1995-03-08 1996-03-07 DEVELOPED IMMUNOGENES OF TOXICITY DERIVED FROM A RETROVIRAL REGULATING PROTEIN ANTIBODIES INTENDED FOR COMBATING THE IMMUNOGENES PREPARATION PROCESS AND PHARMACEUTICAL COMPOSITIONS BY BROUGHTING THEM
BR9607659A BR9607659A (en) 1995-03-08 1996-03-07 Immunogen compound composition processes for preparing an immunogenic compound of an anti-protein antibody and an anti-protein antibody fragment and fragment
JP8526669A JPH11501310A (en) 1995-03-08 1996-03-07 Non-toxic immunogens derived from retroviral regulatory proteins, antibodies, methods of manufacture and pharmaceutical compositions comprising them
OA70071A OA10615A (en) 1995-03-08 1997-09-08 Immunogens devoid of toxicity derived from a retroviral regulatory protein antibody preparation method and pharmaceutical compositions containing them
GR20000402673T GR3034970T3 (en) 1995-03-08 2000-11-30 Non-toxic immunogens derived from a retroviral regulatory protein, antibodies, preparation method therefor, and pharmaceutical compositions containing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9502708A FR2731355B1 (en) 1995-03-08 1995-03-08 NOVEL IMMUNOGENS, NOVEL ANTIBODIES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Publications (2)

Publication Number Publication Date
FR2731355A1 FR2731355A1 (en) 1996-09-13
FR2731355B1 true FR2731355B1 (en) 1997-05-30

Family

ID=9476864

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9502708A Expired - Fee Related FR2731355B1 (en) 1995-03-08 1995-03-08 NOVEL IMMUNOGENS, NOVEL ANTIBODIES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Country Status (6)

Country Link
KR (1) KR100309856B1 (en)
CN (1) CN1226046C (en)
ES (1) ES2150107T5 (en)
FR (1) FR2731355B1 (en)
OA (1) OA10615A (en)
PT (1) PT814834E (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60044303D1 (en) * 1999-08-12 2010-06-10 Inist Inc NON-IMMUNOSUPPRESIVE HIV TAT PROTEIN
US8323928B2 (en) 1999-08-12 2012-12-04 Pin Pharma, Inc. Vaccines and immunotherapeutics derived from the human immunodeficiency virus (HIV) transactivator of transcription protein for the treatment and prevention of HIV disease
FR2844514B1 (en) * 2002-09-16 2007-10-19 Neovacs STABLE IMMUNOGENIC PRODUCT COMPRISING ANTIGENIC HETEROCOMPLEXES, COMPOSITIONS CONTAINING SAME, AND PREPARATION METHOD
EP3077417A1 (en) * 2013-12-08 2016-10-12 Peptcell Limited Hiv antigens and antibodies and compositions, methods and uses thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3756789A (en) * 1988-06-16 1990-01-12 St. Louis University Antagonists of viral transactivating proteins
WO1991015224A1 (en) * 1990-03-30 1991-10-17 Smithkline Beecham Corporation Inhibition of disease associated with immunodeficiency virus infection
WO1991018454A1 (en) * 1990-05-18 1991-11-28 Centre National De La Recherche Scientifique Compositions capable of blocking cytotoxicity of viral regulatory proteins and neurotoxic symptoms associated with retroviral infection
CA2101919A1 (en) * 1991-02-14 1992-08-15 The Regents Of The University Of California Integrin specificity for the hiv tat protein
EP0648226B1 (en) * 1992-04-24 2003-07-23 Institute For Human Genetics And Biochemistry NATURAL HUMAN IgM ANTIBODIES
WO1993025235A1 (en) * 1992-06-09 1993-12-23 President And Fellows Of Harvard College Aids therapeutics based on hiv-2 vpx peptides
WO1994015634A1 (en) * 1992-12-30 1994-07-21 Matthias Rath Tat and rev oligopeptides in hiv treatment
FR2700169B1 (en) * 1993-01-04 1995-03-24 Transgene Sa New TAT trans-dominant variants of the human immunodeficiency virus.
WO1995004546A1 (en) * 1993-08-06 1995-02-16 Kai Juhani Ernst Krohn Novel mutated human and simian immunodeficiency viruses and vaccines containing said viruses

Also Published As

Publication number Publication date
ES2150107T5 (en) 2009-08-05
OA10615A (en) 2002-08-30
KR19980702834A (en) 1998-08-05
CN1226046C (en) 2005-11-09
ES2150107T3 (en) 2000-11-16
KR100309856B1 (en) 2003-03-06
PT814834E (en) 2001-01-31
CN1181020A (en) 1998-05-06
FR2731355A1 (en) 1996-09-13

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CL Concession to grant licences
ST Notification of lapse

Effective date: 20131129