FR2704396A1 - Nutritional supplement which can be taken orally, intended for promoting the elimination of fats and the restoration of balanced nutritional behaviour - Google Patents

Nutritional supplement which can be taken orally, intended for promoting the elimination of fats and the restoration of balanced nutritional behaviour Download PDF

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Publication number
FR2704396A1
FR2704396A1 FR9305321A FR9305321A FR2704396A1 FR 2704396 A1 FR2704396 A1 FR 2704396A1 FR 9305321 A FR9305321 A FR 9305321A FR 9305321 A FR9305321 A FR 9305321A FR 2704396 A1 FR2704396 A1 FR 2704396A1
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France
Prior art keywords
nutritional supplement
vitamin
elimination
nutritional
tyrosine
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Granted
Application number
FR9305321A
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French (fr)
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FR2704396B1 (en
Inventor
Curtay Jean-Paul
Boiron Christian
Abecassis Jacky
Baume Bernard
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Boiron SA
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Boiron SA
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Priority to FR9305321A priority Critical patent/FR2704396B1/en
Publication of FR2704396A1 publication Critical patent/FR2704396A1/en
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Publication of FR2704396B1 publication Critical patent/FR2704396B1/en
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Expired - Fee Related legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15Vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16Inorganic salts, minerals or trace elements
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/175Amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Nutritional supplement which can be taken orally, to promote the elimination of fats and the restoration of balanced nutritional behaviour, which contains, in combination, tyrosine, vitamin C, vitamin E, magnesium and an excipient.

Description

COMPLEMENT NUTRITIONNEL ABSORBABLE DESTINE A
FAVORISER L'ELIMINATION DES GRAISSES ET LE REEOUILIBRAGE
DU COMPORTEMENT ALIMENTAIRE.
ABSORBABLE NUTRITIONAL SUPPLEMENT FOR
PROMOTE FAT REMOVAL AND REWARMING
FOOD BEHAVIOR.

L'invention concerne un complément nutritionnel absorbable, peros, pour favoriser l'élimination des graisses et le rééquilibrage du comportement alimentaire. The invention relates to an absorbable nutritional supplement, peros, to promote the elimination of fat and the rebalancing of eating behavior.

Comme on le sait, l'accumulation des graisses dans le corps augmente les risques de mortalité ou de complications non-négligeables, notamment en ce qui concerne les maladies cardiovasculaires ou les pathologies articulaires. As we know, the accumulation of fat in the body increases the risk of death or significant complications, especially with regard to cardiovascular diseases or joint pathologies.

L'invention vise à pallier ces inconvénients. Elle concerne un complément nutritionnel absorbable per-os qui favorise l'élimination des graisses, ainsi que le rééquilibrage du comportement alimentaire. The invention aims to overcome these drawbacks. It relates to an absorbable per-bone nutritional supplement which promotes the elimination of fat, as well as the rebalancing of eating behavior.

Ce complément nutritionnel absorbable se caractérise en ce qu'il contient en association de la tyrosine, de la vitamine C et de la vitamine
E, du magnésium et un excipient.
This absorbable nutritional supplement is characterized in that it contains in combination with tyrosine, vitamin C and vitamin
E, magnesium and an excipient.

Par "complément nutritionnel", on désigne un ensemble absorbable formant une supplémentation en micronutriments complétant l'alimentation quotidienne, qui permet à la fois d'agir sur un symptôme et en même temps de renforcer l'organisme. By "nutritional supplement" is meant an absorbable whole forming a micronutrient supplementation supplementing the daily diet, which allows both to act on a symptom and at the same time to strengthen the body.

Avantageusement, en pratique, la tyrosine, qui est un amino acide aromatique, se présente sous forme de L-tyrosine.  Advantageously, in practice, tyrosine, which is an aromatic amino acid, is in the form of L-tyrosine.

La proportion de vitamine C est égale à la proportion de L- tyrosine et est de l'ordre de trente (30) fois supérieure à celle de la vitamine E, qui sert essentiellement à stabiliser la vitamine C. La vitamine C favorise la transformation de la tyrosine en noradrénaline, qui est responsable de la mobilisation de l'énergie, chaque fois qu'un effort est à fournir ; cette noradrénaline diminue l'activité de la lipoprotéine lipase (LPL), c'est-àdire l'accumulation de graisses dans les tissus adipeux (lipogénèse). The proportion of vitamin C is equal to the proportion of L-tyrosine and is of the order of thirty (30) times greater than that of vitamin E, which essentially serves to stabilize vitamin C. Vitamin C promotes the transformation of tyrosine to norepinephrine, which is responsible for mobilizing energy, whenever an effort is required; this norepinephrine decreases the activity of lipoprotein lipase (LPL), that is to say the accumulation of fat in adipose tissue (lipogenesis).

Le magnésium se présente sous forme de glycérophosphate de magnésium. Ce composé interréagit avec la vitamine C pour activer la synthèse intracellulaire d'AMP cyclique qui, avec l'aide d'autres messagers, va déclencher la lipolyse, c'est-à-dire la mobilisation des graisses stockées dans le tissu adipeux pour les remettre en circulation; ce glycérophosphate de magnésium permet en outre de rééquilibrer le comportement alimentaire en cas de stress. Magnesium is in the form of magnesium glycerophosphate. This compound interacts with vitamin C to activate the intracellular synthesis of cyclic AMP which, with the help of other messengers, will trigger lipolysis, i.e. the mobilization of fat stored in adipose tissue for put back into circulation; this magnesium glycerophosphate also helps rebalance eating behavior in the event of stress.

En d'autres termes, l'association de la tyrosine, de la vitamine C, stabilisée par la vitamine E et du glycérophosphate de magnésium agit en synergie pour favoriser le déstockage des graisses, leur combustion par d'autres tissus, ainsi que le rééquilibrage du comportement alimentaire au niveau de l'appétit et des facteurs qui peuvent le dérégler comme le stress et le fléchissement de l'humeur. In other words, the combination of tyrosine, vitamin C, stabilized by vitamin E and magnesium glycerophosphate acts synergistically to promote the destocking of fats, their combustion by other tissues, as well as rebalancing. eating behavior related to appetite and factors that can upset it, such as stress and mood swings.

Ainsi, le complément nutritionnel caractéristique de l'invention permet, par une sélection de différents composés qui interréagissent entre eux, de régler d'une manière satisfaisante le problème de la surcharge pondérale. Thus, the nutritional supplement characteristic of the invention allows, by a selection of different compounds which interact with each other, to satisfactorily resolve the problem of overweight.

Comme excipient, on utilise avantageusement du dextrose stabilisé par du stéarate de magnésium, éventuellement coloré par la poudre de spiruline.  As excipient, use is advantageously made of dextrose stabilized with magnesium stearate, optionally colored with spirulina powder.

Dans une forme de réalisation avantageuse, l'association caractéristique de l'invention contient en pour cent en poids:
- 30,91 % de L-tyrosine;
- 30,91 % de vitamine C;
- 24,18 % de glycérophosphate de magnésium;
- 0,91 % de vitamine E à 50 % dans un mélange de gélatine et de
dextrine;
- 13,09 % d'excipient, par exemple:
10,59 % de dextrose;
1,5 % d'un colorant spiruline en poudre;
1 % de stéarate de magnésium.
In an advantageous embodiment, the characteristic association of the invention contains in percent by weight:
- 30.91% L-tyrosine;
- 30.91% vitamin C;
- 24.18% magnesium glycerophosphate;
- 0.91% vitamin E at 50% in a mixture of gelatin and
dextrin;
- 13.09% of excipient, for example:
10.59% dextrose;
1.5% of a powdered spirulina dye;
1% magnesium stearate.

Pour garantir l'intégrité des différents composés, on effectue avantageusement la formulation de la manière suivante. Dans un premier temps, on granule en phase humide les excipients et les principaux composés. Puis, dans un deuxième temps, on mélange en phase sèche les vitamines et les principes actifs fragiles. To guarantee the integrity of the various compounds, the formulation is advantageously carried out in the following manner. Initially, the excipients and the main compounds are granulated in the wet phase. Then, in a second step, vitamins and fragile active ingredients are mixed in the dry phase.

Le complément nutritionnel conforme à l'invention peut être absorbé sous forme de poudre, de gélules, de granules, et avantageusement de comprimés. The nutritional supplement according to the invention can be absorbed in the form of powder, capsules, granules, and advantageously tablets.

Ce complément nutritionnel, sous forme de comprimés de 550 mg, peut être avalé à raison de quatre comprimés avant le déjeuner pendant trois à six mois renouvelable. This nutritional supplement, in the form of 550 mg tablets, can be swallowed at the rate of four tablets before lunch for three to six months, renewable.

Ce complément nutritionnel permet comme déjà dit de favoriser l'élimination des graisses, ainsi que le rééquilibrage du comportement alimentaire.  This nutritional supplement allows, as already said, to promote the elimination of fat, as well as the rebalancing of eating behavior.

Claims (6)

REVENDICATIONS 1/ Complément nutritionnel absorbable, pour favoriser l'élimination des graisses et le rééquilibrage du comportement alimentaire, caractérisé en ce qu'il contient en association de la tyrosine, de la vitamine C, de la vitamine E, du magnésium et un excipient. 1 / Absorbable nutritional supplement, to promote the elimination of fats and the rebalancing of eating behavior, characterized in that it contains in combination with tyrosine, vitamin C, vitamin E, magnesium and an excipient. 2/ Complément nutritionnel selon la revendication 1, caractérisé en ce que la tyrosine se présente sous forme de L-tyrosine. 2 / nutritional supplement according to claim 1, characterized in that the tyrosine is in the form of L-tyrosine. 3/ Complément nutritionnel selon l'une des revendications 1 et 2, caractérisé en ce que la proportion de vitamine C est égale à la proportion de L-tyrosine et est trente (30) fois supérieure à celle de la vitamine E. 3 / Nutritional supplement according to one of claims 1 and 2, characterized in that the proportion of vitamin C is equal to the proportion of L-tyrosine and is thirty (30) times greater than that of vitamin E. 4/ Complément nutritionnel selon l'une des revendications 1 à 3, caractérisé en ce que le magnésium se présente sous forme de glycérophosphate de magnésium. 4 / Nutritional supplement according to one of claims 1 to 3, characterized in that the magnesium is in the form of magnesium glycerophosphate. 5/ Complément nutritionnel selon l'une des revendications I à 4, caractérisé en ce que l'excipient est formé par un mélange de dextrose, stabilisé par du stéarate de magnésium, et coloré par la poudre de spiruline.  5 / Nutritional supplement according to one of claims I to 4, characterized in that the excipient is formed by a mixture of dextrose, stabilized by magnesium stearate, and colored by the powder of spirulina. -13,09 % d'excipient  -13.09% of excipient - 0,91 % de vitamine E à 50 %; - 0.91% vitamin E at 50%; - 24,18 % de glycérophosphate de magnésium; - 24.18% magnesium glycerophosphate; - 30,91 % de vitamine C; - 30.91% vitamin C; - 30,91 % de L-tyrosine; - 30.91% L-tyrosine; 6/ Complément nutritionnel absorbable pour favoriser l'élimination des graisses et le rééquilibrage du comportement alimentaire selon l'une des revendications I à 5, caractérisé en ce qu'il contient en pour cent en poids: 6 / Absorbable nutritional supplement to promote the elimination of fat and the rebalancing of eating behavior according to one of claims I to 5, characterized in that it contains in percent by weight:
FR9305321A 1993-04-29 1993-04-29 Absorbable nutritional supplement intended to promote the elimination of fats and the rebalancing of eating behavior. Expired - Fee Related FR2704396B1 (en)

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FR9305321A FR2704396B1 (en) 1993-04-29 1993-04-29 Absorbable nutritional supplement intended to promote the elimination of fats and the rebalancing of eating behavior.

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FR9305321A FR2704396B1 (en) 1993-04-29 1993-04-29 Absorbable nutritional supplement intended to promote the elimination of fats and the rebalancing of eating behavior.

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FR2704396A1 true FR2704396A1 (en) 1994-11-04
FR2704396B1 FR2704396B1 (en) 1995-06-02

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2758440A1 (en) * 1997-01-21 1998-07-24 Eric Marcel Jean Baseilhac New food supplement to assist weight loss containing oligo- and polysaccharide(s)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0087068A1 (en) * 1982-02-12 1983-08-31 Thomas Moses Dr. Beck Nutritional supplement
US4973467A (en) * 1989-10-13 1990-11-27 Natrol, Inc. Dietary supplement for adults
WO1993002682A1 (en) * 1991-08-06 1993-02-18 Labco Pharmaceuticals, Inc. Method and compositions for reducing craving for alcohol and stimulants

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0087068A1 (en) * 1982-02-12 1983-08-31 Thomas Moses Dr. Beck Nutritional supplement
US4973467A (en) * 1989-10-13 1990-11-27 Natrol, Inc. Dietary supplement for adults
WO1993002682A1 (en) * 1991-08-06 1993-02-18 Labco Pharmaceuticals, Inc. Method and compositions for reducing craving for alcohol and stimulants

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2758440A1 (en) * 1997-01-21 1998-07-24 Eric Marcel Jean Baseilhac New food supplement to assist weight loss containing oligo- and polysaccharide(s)

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Publication number Publication date
FR2704396B1 (en) 1995-06-02

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