FR2696741B1 - Dérivés de 1-(4-chlorophényl)-2-[4-[(4-fluorophényl)méthyl]piperidin-1-yl] éthanol, leur préparation et leur application en thérapeutique. - Google Patents

Dérivés de 1-(4-chlorophényl)-2-[4-[(4-fluorophényl)méthyl]piperidin-1-yl] éthanol, leur préparation et leur application en thérapeutique.

Info

Publication number
FR2696741B1
FR2696741B1 FR9212165A FR9212165A FR2696741B1 FR 2696741 B1 FR2696741 B1 FR 2696741B1 FR 9212165 A FR9212165 A FR 9212165A FR 9212165 A FR9212165 A FR 9212165A FR 2696741 B1 FR2696741 B1 FR 2696741B1
Authority
FR
France
Prior art keywords
piperidin
fluorophenyl
chlorophenyl
methyl
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9212165A
Other languages
English (en)
Other versions
FR2696741A1 (fr
Inventor
John Allen
Joseph Schofield
Thierry Vassal
Jonathan Frost
Jean Bertin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR9212165A priority Critical patent/FR2696741B1/fr
Publication of FR2696741A1 publication Critical patent/FR2696741A1/fr
Application granted granted Critical
Publication of FR2696741B1 publication Critical patent/FR2696741B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
FR9212165A 1992-10-12 1992-10-12 Dérivés de 1-(4-chlorophényl)-2-[4-[(4-fluorophényl)méthyl]piperidin-1-yl] éthanol, leur préparation et leur application en thérapeutique. Expired - Fee Related FR2696741B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR9212165A FR2696741B1 (fr) 1992-10-12 1992-10-12 Dérivés de 1-(4-chlorophényl)-2-[4-[(4-fluorophényl)méthyl]piperidin-1-yl] éthanol, leur préparation et leur application en thérapeutique.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9212165A FR2696741B1 (fr) 1992-10-12 1992-10-12 Dérivés de 1-(4-chlorophényl)-2-[4-[(4-fluorophényl)méthyl]piperidin-1-yl] éthanol, leur préparation et leur application en thérapeutique.

Publications (2)

Publication Number Publication Date
FR2696741A1 FR2696741A1 (fr) 1994-04-15
FR2696741B1 true FR2696741B1 (fr) 1994-11-25

Family

ID=9434435

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9212165A Expired - Fee Related FR2696741B1 (fr) 1992-10-12 1992-10-12 Dérivés de 1-(4-chlorophényl)-2-[4-[(4-fluorophényl)méthyl]piperidin-1-yl] éthanol, leur préparation et leur application en thérapeutique.

Country Status (1)

Country Link
FR (1) FR2696741B1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2728568B1 (fr) * 1994-12-23 1997-04-11 Synthelabo Intermediaires de synthese des enantiomeres de l'eliprodil et leur procede de preparation
FR2742051B1 (fr) * 1995-12-06 1998-02-06 Synthelabo Utilisation de composes ayant une affinite pour le site de liaison du (3h)ifenprodil pour la fabrication de medicaments utiles dans la prevention et le traitement des neuropathies
WO1997033582A1 (fr) * 1996-03-14 1997-09-18 Synthelabo Compositions d'antagonistes de site polyamine
AU2001269540A1 (en) * 2000-07-18 2002-01-30 Sumitomo Pharmaceuticals Co. Ltd. Serotonin reuptake inhibitors
DE10257356A1 (de) * 2002-12-09 2004-06-24 Bayer Ag Fluorhaltige Aromaten
TWI410420B (zh) 2008-02-05 2013-10-01 Dainippon Sumitomo Pharma Co 苄基哌啶化合物
EP2463286A4 (fr) 2009-08-04 2013-01-23 Dainippon Sumitomo Pharma Co Composé de benzylpipéridine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2503705A1 (fr) * 1981-04-14 1982-10-15 Synthelabo Derives de phenethanolamine, leur preparation et leur application en therapeutique
FR2534580A1 (fr) * 1982-10-13 1984-04-20 Synthelabo Derives de phenyl-1 piperidino-2 propanol, leur preparation, et medicaments qui les contiennent
CA1280421C (fr) * 1985-07-02 1991-02-19 Albert A. Carr Derives piperidinyl disubstitutes en 1,4
US5064838A (en) * 1988-01-21 1991-11-12 Merrell Dow Pharmaceuticals 1,4-disubstituted-piperidinyl compounds as pain relievers
FR2628740B3 (fr) * 1989-04-12 1990-01-19 Synthelabo Procede de preparation des enantiomeres du (chloro-4 phenyl)-1 (((fluoro-4 phenyl)methyl)-4 piperidyl-1)-2 ethanol
FR2672286B1 (fr) * 1991-01-31 1994-11-18 Synthelabo Derives de 1-(4-chlorophenyl)-2-[4-(phenylmethyl)piperidin-1-yl]ethanol, leur preparation et leur application en therapeutique.

Also Published As

Publication number Publication date
FR2696741A1 (fr) 1994-04-15

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