FR2681531A1 - A novel process for preparing pharmacologically active onion extract - Google Patents

A novel process for preparing pharmacologically active onion extract Download PDF

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Publication number
FR2681531A1
FR2681531A1 FR9111884A FR9111884A FR2681531A1 FR 2681531 A1 FR2681531 A1 FR 2681531A1 FR 9111884 A FR9111884 A FR 9111884A FR 9111884 A FR9111884 A FR 9111884A FR 2681531 A1 FR2681531 A1 FR 2681531A1
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FR
France
Prior art keywords
novel process
onion extract
pharmacologically active
extract
onion
Prior art date
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Granted
Application number
FR9111884A
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French (fr)
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FR2681531B1 (en
Inventor
Dakar Albert
Dakar Georges
Dakar Helen
Epouse Alkouran
Dakar Rimond
Dakar Boutros
Helou Georges
Gharib Abdallah
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Individual
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Individual
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962Allium, e.g. garden onion, leek, garlic or chives

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a novel process for preparing onion extract. This process employs conditions which are easy to apply and carry out, without technical complications. The liquid varies in colour according to the variety of onion used, and is clear and rich in active substances. The extract is intended for use in medicine and in pharmacy.

Description

La présente invention concerne un procédé de préparation, et le liquide limpide coloré préparé à partir de ce procédé. The present invention relates to a preparation process, and the clear colored liquid prepared from this process.

Le liquide, selon la présente invention, est préparé à partir d'oignons. Sa viscosité est très variée, allant de 20 à 70 m Pa.s. I1 représente l'extrait du bulbe de cette plante potagère après pression; il contient, en particulier mais non exclusivement, des substances actives utilisables en médecine et en pharmacie. The liquid according to the present invention is prepared from onions. Its viscosity is very varied, ranging from 20 to 70 m Pa.s. I1 represents the extract of the bulb of this vegetable plant after pressing; it contains, in particular but not exclusively, active substances usable in medicine and in pharmacy.

Le liquide limpide, selon la présente invention, peut être utilisé dans toutes les formes pharmaceutiques à usage externe et interne, comme cicatrisant, calmant et désinfectant. The clear liquid according to the present invention can be used in all pharmaceutical forms for external and internal use, as a healing, calming and disinfecting agent.

Le liquide est obtenu par un procédé simple, l'extraction est faite dans des conditions ci-après détaillées, et qui font également l'objet de la présente invention. The liquid is obtained by a simple process, the extraction is carried out under conditions detailed below, and which are also the subject of the present invention.

Les caractéristiques et avantages de la présente invention apparaissent à la lecture détaillée faite ci-après, notamment en référence à quelques exemples de mise en oeuvre du procédé de l'invention, donnés à titre de simple illustration. The characteristics and advantages of the present invention appear on detailed reading made below, in particular with reference to some examples of implementation of the method of the invention, given by way of simple illustration.

Matière première et description de la partie utilisée
Oignon : plante potagère à bulbe comestible de la famille liliacée (Allium Cepa
L).
Raw material and description of the part used
Onion: edible bulb vegetable plant of the liliaceous family (Allium Cepa
L).

Bulbe de l'oignon : l'organe végétal formé par un bourgeon souterrain, portant de nombreuses feuilles très rapprochées et charnues, remplies de réserves nutritives, permettant à la plante de reformer chaque année ses parties aériennes. Bulb of the onion: the plant organ formed by an underground bud, bearing numerous closely packed and fleshy leaves, filled with nutritive reserves, allowing the plant to reform its aerial parts each year.

Partie utilisée : le bulbe de l'oignon épluché. Part used: the bulb of the peeled onion.

Mode opératoire:
De nombreux procédés sont décrits pour la préparation de l'extrait de l'oignon.
Procedure:
Many processes are described for the preparation of the onion extract.

Dans ce texte, qui concerne la présente invention, on propose un nouveau procédé présentant une préparation d'un liquide limpide qui est ltextrait de l'oignon.  In this text, which relates to the present invention, a new method is proposed presenting a preparation of a clear liquid which is the text of the onion.

Les caractéristiques et avantages du procédé, résident dans: - un procédé simple et facile à appliquer sans complications techniques; - un meilleur rendement des substances actives; - une conservation parfaite des substances actives; - un produit de qualité; - des conditions nouvelles suivant le protocole illustré dans la figure 1 (page 4)
Description de la préparation
Liquide limpide de:
- couleur : variable selon la variété de l'oignon choisie
- viscosité : 20 - 50 Pa.s -pH:5-5,5
- pression osmotique: 2800 - 3100 mO / kg
Exemple:
120 g (oignons) sont coupés et mixés avec 120 ml d'éthanol (95 %). Le mélange (200 ml) est placé dans un évaporateur rotatif pendant 150 minutes à 40 "C.
The characteristics and advantages of the process reside in: - a simple and easy to apply process without technical complications; - better yield of active substances; - perfect conservation of active substances; - a quality product; - new conditions according to the protocol illustrated in Figure 1 (page 4)
Description of the preparation
Clear liquid from:
- color: variable depending on the variety of onion chosen
- viscosity: 20 - 50 Pa.s -pH: 5-5.5
- osmotic pressure: 2800 - 3100 mO / kg
Example:
120 g (onions) are cut and mixed with 120 ml of ethanol (95%). The mixture (200 ml) is placed in a rotary evaporator for 150 minutes at 40 "C.

Le mélange est filtré. Le liquide récupéré est réduit sous vide à 75% de son volume.The mixture is filtered. The recovered liquid is reduced under vacuum to 75% of its volume.

15% de sucre sont ajoutés.L'extrait final est stérilisé par filtration. 2% d'édulcrant sont additionnés à cet extrait. On obtient 30 ml de produit.  15% sugar is added. The final extract is sterilized by filtration. 2% of sweetener are added to this extract. 30 ml of product are obtained.

Claims (5)

RevendicationsClaims 1 - Nouveau pocédé pour la préparation de l'extrait de l'oignon, un liquide limpide1 - New process for the preparation of the onion extract, a clear liquid blancjaunâtre, caractérisé en ce qu'il comporte plusieurs opérations: whitish-white, characterized in that it comprises several operations: - broyage du bulbe - grinding of the bulb - extraction et filtration - extraction and filtration - réduction - reduction - stérilisation par filtration - sterilization by filtration 2 - Le procédé, selon la revendication 1, caractérisé en ce que la température de 2 - The method according to claim 1, characterized in that the temperature of l'extraction soit compnse entre 35 et 50 C sous vide et pendant 120 à 150 minutes. the extraction is between 35 and 50 C under vacuum and for 120 to 150 minutes. 3 - Le procédé selon l'une quelconque des revendications précédentes, caractérisé en ce 3 - The method according to any one of the preceding claims, characterized in that que l'alcool 85 - 95" est ajouté à l'homogénat de bulbe tout de suite après la that 85-95 "alcohol is added to the bulb homogenate immediately after pression. pressure. 4 - Le liquide limpide, obtenu selon le procédé dans l'une quelconque des 4 - The clear liquid, obtained according to the process in any one of revendications précédentes, caractérisé en ce qu'il contient de 50 à 60 % alcool 85  previous claims, characterized in that it contains from 50 to 60% alcohol 85 95 , sucre à 10 - 20 % et un édulcorant à 2 %. 95, 10-20% sugar and a 2% sweetener. 5 - Le liquide obtenu, selon les revendications de 1 à 4, peut être utilisé dans les formes 5 - The liquid obtained, according to claims 1 to 4, can be used in the forms pharmaceutiques à usage interne et externe comme cicatrisant, calmant et désinfectant.  pharmaceuticals for internal and external use as a healing, calming and disinfectant.
FR9111884A 1991-09-20 1991-09-20 A NEW PROCESS FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE ONION EXTRACT. Expired - Fee Related FR2681531B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR9111884A FR2681531B1 (en) 1991-09-20 1991-09-20 A NEW PROCESS FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE ONION EXTRACT.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9111884A FR2681531B1 (en) 1991-09-20 1991-09-20 A NEW PROCESS FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE ONION EXTRACT.

Publications (2)

Publication Number Publication Date
FR2681531A1 true FR2681531A1 (en) 1993-03-26
FR2681531B1 FR2681531B1 (en) 1993-12-24

Family

ID=9417337

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FR9111884A Expired - Fee Related FR2681531B1 (en) 1991-09-20 1991-09-20 A NEW PROCESS FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE ONION EXTRACT.

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FR (1) FR2681531B1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003004043A1 (en) * 2001-07-03 2003-01-16 Merz Pharma Gmbh & Co. Kgaa Agent containing fat (oil), which contains onion extract, the production and use thereof for caring, preventing or treating damaged skin tissue, especially scarred tissue

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3305951A1 (en) * 1983-02-21 1984-08-23 Walter Dr Dorsch Pharmaceutical composition for the treatment of bronchial asthma

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3305951A1 (en) * 1983-02-21 1984-08-23 Walter Dr Dorsch Pharmaceutical composition for the treatment of bronchial asthma

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GABRIEL GARNIER ET AL: 'RESSOURCES MEDICINALES DE LA FLORE FRANçAISE' , VIGOT FRERES EDITEURS , PARIS ALLIUM CEPA *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003004043A1 (en) * 2001-07-03 2003-01-16 Merz Pharma Gmbh & Co. Kgaa Agent containing fat (oil), which contains onion extract, the production and use thereof for caring, preventing or treating damaged skin tissue, especially scarred tissue
ES2217983A1 (en) * 2001-07-03 2004-11-01 MERZ PHARMA GMBH & CO. KGAA Agent containing fat (oil), which contains onion extract, the production and use thereof for caring, preventing or treating damaged skin tissue, especially scarred tissue
EP1566179A2 (en) * 2001-07-03 2005-08-24 Merz Pharma GmbH & Co. KGaA Agent containing fat (oil) which contains onion extract, the production and use thereof
EP1566179A3 (en) * 2001-07-03 2005-11-09 Merz Pharma GmbH & Co. KGaA Agent containing fat (oil) which contains onion extract, the production and use thereof

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FR2681531B1 (en) 1993-12-24

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