FR2679565B1 - Analogues de l'hirudine, leur procede de preparation et leur application en therapeutique. - Google Patents

Analogues de l'hirudine, leur procede de preparation et leur application en therapeutique.

Info

Publication number
FR2679565B1
FR2679565B1 FR9209045A FR9209045A FR2679565B1 FR 2679565 B1 FR2679565 B1 FR 2679565B1 FR 9209045 A FR9209045 A FR 9209045A FR 9209045 A FR9209045 A FR 9209045A FR 2679565 B1 FR2679565 B1 FR 2679565B1
Authority
FR
France
Prior art keywords
hirudine
therapeutics
analogs
application
preparation process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9209045A
Other languages
English (en)
Other versions
FR2679565A1 (fr
Inventor
Marco Gerna
Philippe De Taxis Du Poet
Antonio Molinari
Romeo Scacheri Emanuelaroncucc
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MINISTERO UNI RICERCA SCI
Original Assignee
MINISTERO UNI RICERCA SCI
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MINISTERO UNI RICERCA SCI filed Critical MINISTERO UNI RICERCA SCI
Publication of FR2679565A1 publication Critical patent/FR2679565A1/fr
Application granted granted Critical
Publication of FR2679565B1 publication Critical patent/FR2679565B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/815Protease inhibitors from leeches, e.g. hirudin, eglin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FR9209045A 1991-07-22 1992-07-22 Analogues de l'hirudine, leur procede de preparation et leur application en therapeutique. Expired - Fee Related FR2679565B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI912019A IT1250689B (it) 1991-07-22 1991-07-22 Analoghi dell'irudina e procedimento per la loro preparazione

Publications (2)

Publication Number Publication Date
FR2679565A1 FR2679565A1 (fr) 1993-01-29
FR2679565B1 true FR2679565B1 (fr) 1995-02-03

Family

ID=11360396

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9209045A Expired - Fee Related FR2679565B1 (fr) 1991-07-22 1992-07-22 Analogues de l'hirudine, leur procede de preparation et leur application en therapeutique.

Country Status (4)

Country Link
DE (1) DE4224213A1 (fr)
FR (1) FR2679565B1 (fr)
GB (1) GB2257974B (fr)
IT (1) IT1250689B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL101062A0 (en) * 1991-02-28 1992-11-15 Erba Carlo Spa Anti-thrombin polypeptides and their preparation
DE4404168A1 (de) * 1994-02-10 1995-08-17 Hoechst Ag Hirudinderivate und Verfahren zu deren Herstellung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1341032C (fr) * 1987-01-23 2000-06-20 John L. Krstenansky Peptides anti-coagulants
JP2653820B2 (ja) * 1988-03-14 1997-09-17 壽之 松尾 アミド化酵素及びその製造方法
GB8916289D0 (en) * 1989-07-17 1989-08-31 Erba Carlo Spa Cofactor for the pam enzyme
CA2026376C (fr) * 1989-10-03 2002-01-01 John L. Krstenansky Peptides anticoagulants

Also Published As

Publication number Publication date
FR2679565A1 (fr) 1993-01-29
GB2257974A (en) 1993-01-27
DE4224213A1 (de) 1993-01-28
ITMI912019A1 (it) 1993-01-22
GB2257974B (en) 1995-06-07
IT1250689B (it) 1995-04-21
GB9215552D0 (en) 1992-09-02
ITMI912019A0 (it) 1991-07-22

Similar Documents

Publication Publication Date Title
FR2629715B1 (fr) Derives de l'adenosine, leur procede de preparation et leur utilisation en therapeutique
FR2617170B1 (fr) Nouveaux derives peptidiques et leur application notamment en therapeutique
FR2606410B1 (fr) Imidazopyridines, leur preparation et leur application en therapeutique
FR2506306B1 (fr) Nouveaux derives de l'amidinopiperidine, leur procede de preparation et leur application en therapeutique
FR2689508B1 (fr) Derives de l'imidazole, leur procede de preparation et leur application en therapeutique.
FR2543140B1 (fr) Nouveaux acides flavone-carboxyliques-4', leur methode de preparation et leur application en therapeutique
BE858356A (fr) Derives d'acide 7-acylamino-8-oxo-3-oxa-1-azabicyclo-(4.2.0)octane-2-carboxylique, leur procede de preparation et leur application en therapeutique
ZA854334B (en) Novel lactones,process for their preparation and the use thereof in pest control
FR2682371B1 (fr) Phyllosilicates 2:1 trioctaedriques et leur procede de preparation.
FR2572070B1 (fr) Derives de la chalcone utiles en therapeutique
FR2668031B1 (fr) Bouillies bordelaises et leur procede de preparation.
FR2679565B1 (fr) Analogues de l'hirudine, leur procede de preparation et leur application en therapeutique.
FR2608160B1 (fr) Nouveaux derives peptidiques et leur application notamment en therapeutique
FR2673930B1 (fr) Nouveaux phyllosilicates 2:1 dioctraedriques et leur procede de preparation.
FR2690917B1 (fr) Aminoesters, leur procede de preparation et leur application en therapeutique.
FR2564462B1 (fr) Derives de la 2-phenyl-morpholine utiles en therapeutique
FR2541994B1 (fr) Nouveaux derives d'ester phenylacetique, leur procede de preparation et leur application en therapeutique
ZA878324B (en) New 2,6-diamino-3-halobenzylpyridines and processes for their manufacture as well as their use in pharmaceuticals
FR2544308B1 (fr) Ethines substituees, leur preparation et leur application en therapeutique
FR2683552B1 (fr) Phyllosilicates 2:1 trioctaedriques non gonflants et leur procede de preparation.
BE891468A (fr) Derives d'imidazole, leur procede de preparation et leur application therapeutique
BE895237A (fr) Nouveaux derives tetrazoliques substitues en position 5, leur procede de preparation et leur application en therapeutique
FR2688221B1 (fr) Estratrienol-beta-d-thioxylosides, leur procede de preparation et leur utilisation en therapeutique.
FR2632305B1 (fr) Amino-4 aroyl-3 quinoleines et naphtyridines, leur procede de preparation et leur application en therapeutique
FR2684674B1 (fr) Azapeptides et leur procede de preparation.

Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20070330