FR2679125B1 - Utilisation d'au moins un transducteur piezo-electrique composite pour la fabrication d'un appareil de therapie ultrasonique pour la therapie notamment de concretions, de tissus ou des os d'un etre vivant.. - Google Patents
Utilisation d'au moins un transducteur piezo-electrique composite pour la fabrication d'un appareil de therapie ultrasonique pour la therapie notamment de concretions, de tissus ou des os d'un etre vivant..Info
- Publication number
- FR2679125B1 FR2679125B1 FR9109197A FR9109197A FR2679125B1 FR 2679125 B1 FR2679125 B1 FR 2679125B1 FR 9109197 A FR9109197 A FR 9109197A FR 9109197 A FR9109197 A FR 9109197A FR 2679125 B1 FR2679125 B1 FR 2679125B1
- Authority
- FR
- France
- Prior art keywords
- therapy
- concretions
- bones
- fabrics
- living
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000002560 therapeutic procedure Methods 0.000 title 2
- 239000002131 composite material Substances 0.000 title 1
- 239000004744 fabric Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N7/02—Localised ultrasound hyperthermia
- A61N7/022—Localised ultrasound hyperthermia intracavitary
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B17/22004—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
- A61B17/22012—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves in direct contact with, or very close to, the obstruction or concrement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B17/22004—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
- A61B17/22012—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves in direct contact with, or very close to, the obstruction or concrement
- A61B17/2202—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves in direct contact with, or very close to, the obstruction or concrement the ultrasound transducer being inside patient's body at the distal end of the catheter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N7/02—Localised ultrasound hyperthermia
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B06—GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS IN GENERAL
- B06B—METHODS OR APPARATUS FOR GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS OF INFRASONIC, SONIC, OR ULTRASONIC FREQUENCY, e.g. FOR PERFORMING MECHANICAL WORK IN GENERAL
- B06B1/00—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency
- B06B1/02—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy
- B06B1/06—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy operating with piezoelectric effect or with electrostriction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
- A61B2017/00238—Type of minimally invasive operation
- A61B2017/00274—Prostate operation, e.g. prostatectomy, turp, bhp treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B17/22004—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
- A61B17/22012—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves in direct contact with, or very close to, the obstruction or concrement
- A61B17/2202—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves in direct contact with, or very close to, the obstruction or concrement the ultrasound transducer being inside patient's body at the distal end of the catheter
- A61B2017/22021—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves in direct contact with, or very close to, the obstruction or concrement the ultrasound transducer being inside patient's body at the distal end of the catheter electric leads passing through the catheter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B17/22004—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
- A61B17/22012—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves in direct contact with, or very close to, the obstruction or concrement
- A61B2017/22025—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves in direct contact with, or very close to, the obstruction or concrement applying a shock wave
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B17/22004—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
- A61B2017/22027—Features of transducers
- A61B2017/22028—Features of transducers arrays, e.g. phased arrays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00547—Prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N2007/0078—Ultrasound therapy with multiple treatment transducers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N2007/0086—Beam steering
- A61N2007/0095—Beam steering by modifying an excitation signal
Priority Applications (21)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9109197A FR2679125B1 (fr) | 1991-07-19 | 1991-07-19 | Utilisation d'au moins un transducteur piezo-electrique composite pour la fabrication d'un appareil de therapie ultrasonique pour la therapie notamment de concretions, de tissus ou des os d'un etre vivant.. |
US07/823,306 US5316000A (en) | 1991-03-05 | 1992-01-21 | Use of at least one composite piezoelectric transducer in the manufacture of an ultrasonic therapy apparatus for applying therapy, in a body zone, in particular to concretions, to tissue, or to bones, of a living being and method of ultrasonic therapy |
AT92905392T ATE226417T1 (de) | 1991-03-05 | 1992-02-25 | Therapeutische endorectalsonde zur behandlung von tumorgewebe, insbesondere der prostata |
EP00201992A EP1034745B1 (fr) | 1991-03-05 | 1992-02-25 | Sonde thérapeutique endo-rectale, destinée en particulier au traitement du cancer de la prostate, en combinaison avec sonde d'imagerie endocavitaire |
DE69232831T DE69232831T2 (de) | 1991-03-05 | 1992-02-25 | Therapeutische Endorectalsonde zur Behandlung von Tumorgewebe, insbesondere der Prostata |
PCT/EP1992/000410 WO1992015253A1 (fr) | 1991-03-05 | 1992-02-25 | Sonde therapeutique endo-rectale, destinee en particulier au traitement du cancer de la prostate |
DE69232901T DE69232901T2 (de) | 1991-03-05 | 1992-02-25 | Therapeutische Endorectalsonde, insbesondere für Behandlung von Prostatakarzinom, in Kombination mit einer endoskopischen Bildsonde |
JP4504939A JPH06509241A (ja) | 1991-03-05 | 1992-02-25 | 治療用、特に前立腺癌治療用の直腸プローブ |
AT00201992T ATE230954T1 (de) | 1991-03-05 | 1992-02-25 | Therapeutische endorectalsonde, insbesondere für behandlung von prostatakarzinom, in kombination mit einer endoskopischen bildsonde |
CA002105401A CA2105401C (fr) | 1991-03-05 | 1992-02-25 | Sonde endorectale therapeutique, en particulier pour le traitement du cancer de la prostate |
EP92905392A EP0575363B1 (fr) | 1991-03-05 | 1992-02-25 | Sonde therapeutique endo-rectale destinee au traitement du tissue cancereuse, en particulier de la prostate |
IL101134A IL101134A0 (en) | 1991-03-05 | 1992-03-04 | Therapeutic endo-rectal probe,and apparatus constituting an application thereof for destroying cancer tissue,in particular of the prostate,and preferably in combination with an imaging endo-urethral probe |
DE69227688T DE69227688T2 (de) | 1991-07-19 | 1992-07-08 | Verwendung von piezoelektrischem kompositwandler für ultrasonische therapievorrichtung |
EP92914481A EP0595849B1 (fr) | 1991-07-19 | 1992-07-08 | Utilisation d'un transducteur piezoelectrique dans la fabrication d'un appareil therapeutique ultrasonique |
PCT/EP1992/001534 WO1993001752A1 (fr) | 1991-07-19 | 1992-07-08 | Utilisation d'un transducteur piezoelectrique dans la fabrication d'un appareil therapeutique ultrasonique |
IL10251692A IL102516A (en) | 1991-07-19 | 1992-07-15 | Device for performing therapeutic treatment on an area of the body |
US08/200,877 US5474071A (en) | 1991-03-05 | 1994-02-22 | Therapeutic endo-rectal probe and apparatus constituting an application thereof for destroying cancer tissue, in particular of the prostate, and preferably in combination with an imaging endo-cavitary-probe |
US08/486,738 US5666954A (en) | 1991-03-05 | 1995-06-07 | Therapeutic endo-rectal probe, and apparatus constituting an application thereof for destroying cancer tissue, in particular of the prostate, and preferably in combination with an imaging endo-cavitary-probe |
JP35666299A JP3368241B2 (ja) | 1991-03-05 | 1999-12-15 | 治療用、特に前立腺癌治療用の直腸プローブ |
JP2002211245A JP2003126111A (ja) | 1991-03-05 | 2002-07-19 | 治療用、特に前立腺癌治療用の直腸プローブ |
IL15339202A IL153392A0 (en) | 1991-03-05 | 2002-12-11 | A therapeutic endo-rectal probe and apparatus constituting an application thereof for destroying cancer tissue, in particular of the prostate, in combination with an imaging endo-cavitary-probe |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9109197A FR2679125B1 (fr) | 1991-07-19 | 1991-07-19 | Utilisation d'au moins un transducteur piezo-electrique composite pour la fabrication d'un appareil de therapie ultrasonique pour la therapie notamment de concretions, de tissus ou des os d'un etre vivant.. |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2679125A1 FR2679125A1 (fr) | 1993-01-22 |
FR2679125B1 true FR2679125B1 (fr) | 1993-11-26 |
Family
ID=9415352
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR9109197A Expired - Fee Related FR2679125B1 (fr) | 1991-03-05 | 1991-07-19 | Utilisation d'au moins un transducteur piezo-electrique composite pour la fabrication d'un appareil de therapie ultrasonique pour la therapie notamment de concretions, de tissus ou des os d'un etre vivant.. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0595849B1 (fr) |
DE (1) | DE69227688T2 (fr) |
FR (1) | FR2679125B1 (fr) |
IL (1) | IL102516A (fr) |
WO (1) | WO1993001752A1 (fr) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2720260B1 (fr) | 1994-05-30 | 1996-09-27 | Technomed Medical Systems | Utilisation d'un échographe en mode A pour la surveillance de la position d'un patient pendant une séance de thérapie, et procédé et appareil en comportant application. |
US6740108B1 (en) | 2001-04-05 | 2004-05-25 | Urologix, Inc. | Thermal treatment catheter having preferential asymmetrical heating pattern |
FR2849781B1 (fr) | 2003-01-14 | 2005-03-25 | Edap S A | Sonde de therapie |
WO2004089188A2 (fr) | 2003-03-31 | 2004-10-21 | Liposonix, Inc. | Transducteur de vortex |
BRPI0418242A (pt) * | 2003-12-30 | 2007-04-17 | Liposonix Inc | transdutor para ultra-som, conjuntos de transdutor e de instrumentos médicos eletrÈnicos intercambiáveis |
US8535228B2 (en) | 2004-10-06 | 2013-09-17 | Guided Therapy Systems, Llc | Method and system for noninvasive face lifts and deep tissue tightening |
US10864385B2 (en) | 2004-09-24 | 2020-12-15 | Guided Therapy Systems, Llc | Rejuvenating skin by heating tissue for cosmetic treatment of the face and body |
US8444562B2 (en) | 2004-10-06 | 2013-05-21 | Guided Therapy Systems, Llc | System and method for treating muscle, tendon, ligament and cartilage tissue |
US20060111744A1 (en) | 2004-10-13 | 2006-05-25 | Guided Therapy Systems, L.L.C. | Method and system for treatment of sweat glands |
US11235179B2 (en) | 2004-10-06 | 2022-02-01 | Guided Therapy Systems, Llc | Energy based skin gland treatment |
US9827449B2 (en) | 2004-10-06 | 2017-11-28 | Guided Therapy Systems, L.L.C. | Systems for treating skin laxity |
US9694212B2 (en) | 2004-10-06 | 2017-07-04 | Guided Therapy Systems, Llc | Method and system for ultrasound treatment of skin |
JP5094402B2 (ja) | 2004-10-06 | 2012-12-12 | ガイデッド セラピー システムズ, エル.エル.シー. | 超音波組織処理ための方法およびシステム |
US8133180B2 (en) | 2004-10-06 | 2012-03-13 | Guided Therapy Systems, L.L.C. | Method and system for treating cellulite |
US11207548B2 (en) | 2004-10-07 | 2021-12-28 | Guided Therapy Systems, L.L.C. | Ultrasound probe for treating skin laxity |
KR102352609B1 (ko) | 2008-06-06 | 2022-01-18 | 얼테라, 인크 | 초음파 치료 시스템 |
JP2012513837A (ja) | 2008-12-24 | 2012-06-21 | ガイデッド セラピー システムズ, エルエルシー | 脂肪減少および/またはセルライト処置のための方法およびシステム |
US9510802B2 (en) | 2012-09-21 | 2016-12-06 | Guided Therapy Systems, Llc | Reflective ultrasound technology for dermatological treatments |
CN113648551A (zh) | 2013-03-08 | 2021-11-16 | 奥赛拉公司 | 用于多焦点超声治疗的装置和方法 |
MX371246B (es) | 2014-04-18 | 2020-01-22 | Ulthera Inc | Terapia de ultrasonido con transductor de banda. |
WO2017127328A1 (fr) | 2016-01-18 | 2017-07-27 | Ulthera, Inc. | Dispositif à ultrasons compact possédant un réseau à ultrasons périphérique annulaire électriquement connecté à une carte de circuit imprimé flexible et son procédé d'assemblage |
RU2748788C2 (ru) | 2016-08-16 | 2021-05-31 | Ультера, Инк. | Системы и способы для косметической ультразвуковой обработки кожи |
CN112245818B (zh) * | 2020-09-09 | 2022-05-17 | 深圳先进技术研究院 | 超声神经调控装置 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4622972A (en) * | 1981-10-05 | 1986-11-18 | Varian Associates, Inc. | Ultrasound hyperthermia applicator with variable coherence by multi-spiral focusing |
DE3319871A1 (de) * | 1983-06-01 | 1984-12-06 | Richard Wolf Gmbh, 7134 Knittlingen | Piezoelektrischer wandler zur zerstoerung von konkrementen im koerperinnern |
US4514247A (en) * | 1983-08-15 | 1985-04-30 | North American Philips Corporation | Method for fabricating composite transducers |
DE3425992C2 (de) * | 1984-07-14 | 1986-10-09 | Richard Wolf Gmbh, 7134 Knittlingen | Piezoelektrischer Wandler zur Zerstörung von Konkrementen im Körperinneren |
DE3803275A1 (de) * | 1988-02-04 | 1989-08-17 | Dornier Medizintechnik | Piezoelektrische stosswellenquelle |
FR2642640B1 (fr) | 1989-02-08 | 1991-05-10 | Centre Nat Rech Scient | Procede et dispositif de focalisation d'ultrasons dans les tissus |
DE3932364A1 (de) * | 1989-09-28 | 1991-04-11 | Wolf Gmbh Richard | Vorrichtung zur raeumlichen ortung und zur zerstoerung von koerperinneren objekten |
FR2660561B1 (fr) | 1990-04-06 | 1994-05-13 | Technomed International | Sonde rectale. |
FR2673542B1 (fr) | 1991-03-05 | 1993-07-09 | Technomed Int Sa | Sonde endo-rectale de therapie et appareil de destruction de tissus tumoraux, en particulier de la prostate, en comportant application de preference en combinaison avec une sonde endo-uretrale de visualisation. |
-
1991
- 1991-07-19 FR FR9109197A patent/FR2679125B1/fr not_active Expired - Fee Related
-
1992
- 1992-07-08 WO PCT/EP1992/001534 patent/WO1993001752A1/fr active IP Right Grant
- 1992-07-08 DE DE69227688T patent/DE69227688T2/de not_active Expired - Lifetime
- 1992-07-08 EP EP92914481A patent/EP0595849B1/fr not_active Expired - Lifetime
- 1992-07-15 IL IL10251692A patent/IL102516A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0595849A1 (fr) | 1994-05-11 |
IL102516A0 (en) | 1993-01-14 |
FR2679125A1 (fr) | 1993-01-22 |
WO1993001752A1 (fr) | 1993-02-04 |
EP0595849B1 (fr) | 1998-11-25 |
DE69227688T2 (de) | 1999-07-01 |
IL102516A (en) | 1996-01-31 |
DE69227688D1 (de) | 1999-01-07 |
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