FR2657880A1 - Production de proteines recombinantes a partir de cellules lymphoblastouides humaines et d'heteromyelomes. - Google Patents

Production de proteines recombinantes a partir de cellules lymphoblastouides humaines et d'heteromyelomes. Download PDF

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Publication number
FR2657880A1
FR2657880A1 FR9001239A FR9001239A FR2657880A1 FR 2657880 A1 FR2657880 A1 FR 2657880A1 FR 9001239 A FR9001239 A FR 9001239A FR 9001239 A FR9001239 A FR 9001239A FR 2657880 A1 FR2657880 A1 FR 2657880A1
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FR
France
Prior art keywords
line according
epo
sequence
cells
gene
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR9001239A
Other languages
English (en)
French (fr)
Other versions
FR2657880B1 (enrdf_load_stackoverflow
Inventor
Lopez Claude
Ballay Annick
Chretien Stany
Prigent Sylvie
Boffa Georges
Salmon Charles
Cartron Jean-Pierre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FONDATION NALE TRANSFUSION SAN
Original Assignee
FONDATION NALE TRANSFUSION SAN
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Publication date
Application filed by FONDATION NALE TRANSFUSION SAN filed Critical FONDATION NALE TRANSFUSION SAN
Priority to FR9001239A priority Critical patent/FR2657880A1/fr
Publication of FR2657880A1 publication Critical patent/FR2657880A1/fr
Application granted granted Critical
Publication of FR2657880B1 publication Critical patent/FR2657880B1/fr
Granted legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/505Erythropoietin [EPO]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00Nucleic acids vectors
    • C12N2800/10Plasmid DNA
    • C12N2800/108Plasmid DNA episomal vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00Vectors comprising a special translation-regulating system
    • C12N2840/20Vectors comprising a special translation-regulating system translation of more than one cistron

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FR9001239A 1990-02-02 1990-02-02 Production de proteines recombinantes a partir de cellules lymphoblastouides humaines et d'heteromyelomes. Granted FR2657880A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR9001239A FR2657880A1 (fr) 1990-02-02 1990-02-02 Production de proteines recombinantes a partir de cellules lymphoblastouides humaines et d'heteromyelomes.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9001239A FR2657880A1 (fr) 1990-02-02 1990-02-02 Production de proteines recombinantes a partir de cellules lymphoblastouides humaines et d'heteromyelomes.

Publications (2)

Publication Number Publication Date
FR2657880A1 true FR2657880A1 (fr) 1991-08-09
FR2657880B1 FR2657880B1 (enrdf_load_stackoverflow) 1994-08-19

Family

ID=9393348

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9001239A Granted FR2657880A1 (fr) 1990-02-02 1990-02-02 Production de proteines recombinantes a partir de cellules lymphoblastouides humaines et d'heteromyelomes.

Country Status (1)

Country Link
FR (1) FR2657880A1 (enrdf_load_stackoverflow)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0658627A3 (en) * 1993-12-15 1996-12-11 Hayashibara Biochem Lab DNA recombined with the alpha interferon promoter.
US5820868A (en) * 1993-12-09 1998-10-13 Veterinary Infectious Disease Organization Recombinant protein production in bovine adenovirus expression vector system
US6319716B1 (en) 1997-06-23 2001-11-20 University Of Saskatchewan Bovine adenovirus type 3 genome and vector systems derived therefrom

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0232034A2 (en) * 1986-01-23 1987-08-12 Sumitomo Chemical Company, Limited Production of human erythropoietin
EP0236059A2 (en) * 1986-02-27 1987-09-09 Snow Brand Milk Products Co. Ltd. Preparation of erythropoietin-producing cells and production process of erythropoietin using same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0232034A2 (en) * 1986-01-23 1987-08-12 Sumitomo Chemical Company, Limited Production of human erythropoietin
EP0236059A2 (en) * 1986-02-27 1987-09-09 Snow Brand Milk Products Co. Ltd. Preparation of erythropoietin-producing cells and production process of erythropoietin using same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GENE, vol. 76, no. 1, 15 mars 1989, pages 19-26; H. YANAGI et al.: "Expression of human erythropoietin cDNA in human lymphoblastoid Namalwa cells: the inconsistency of a stable expression level with transient expression efficiency" *

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5820868A (en) * 1993-12-09 1998-10-13 Veterinary Infectious Disease Organization Recombinant protein production in bovine adenovirus expression vector system
US6001591A (en) * 1993-12-09 1999-12-14 University Of Saskatchewan Recombinant bovine adenoviruses
US6086890A (en) * 1993-12-09 2000-07-11 University Of Saskatchewan Bovine adenovirus expression vector system
US6379944B1 (en) 1993-12-09 2002-04-30 University Of Saskatchewan Mammalian cell lines expressing bovine adenovirus functions
US7025967B2 (en) 1993-12-09 2006-04-11 University Of Saskatchewan Recombinant protein production in bovine adenovirus expression vector system
EP0658627A3 (en) * 1993-12-15 1996-12-11 Hayashibara Biochem Lab DNA recombined with the alpha interferon promoter.
US5731193A (en) * 1993-12-15 1998-03-24 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Recombinant DNA and transformant containing the same
US6319716B1 (en) 1997-06-23 2001-11-20 University Of Saskatchewan Bovine adenovirus type 3 genome and vector systems derived therefrom

Also Published As

Publication number Publication date
FR2657880B1 (enrdf_load_stackoverflow) 1994-08-19

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