FR2643818A1 - Method for sterilising many medical, surgical and pharmaceutical articles by the use of the removal of air followed by the flow of ethylene oxide in a closed cycle - Google Patents

Method for sterilising many medical, surgical and pharmaceutical articles by the use of the removal of air followed by the flow of ethylene oxide in a closed cycle Download PDF

Info

Publication number
FR2643818A1
FR2643818A1 FR8816628A FR8816628A FR2643818A1 FR 2643818 A1 FR2643818 A1 FR 2643818A1 FR 8816628 A FR8816628 A FR 8816628A FR 8816628 A FR8816628 A FR 8816628A FR 2643818 A1 FR2643818 A1 FR 2643818A1
Authority
FR
France
Prior art keywords
air
sterilization
gas
ethylene oxide
chamber
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
FR8816628A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AWAD MAHMOUD
Original Assignee
AWAD MAHMOUD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AWAD MAHMOUD filed Critical AWAD MAHMOUD
Priority to FR8816628A priority Critical patent/FR2643818A1/en
Publication of FR2643818A1 publication Critical patent/FR2643818A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/20—Gaseous substances, e.g. vapours
    • A61L2/206—Ethylene oxide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)

Abstract

Method of sterilisation by the use of the removal of air and the flow of ethylene oxide in a closed cycle. The invention relates to a new method of sterilisation by the use of ethylene oxide gas but in a closed cycle. This method consists in placing the articles to be sterilised in a hermetically closed sterilisation chamber from which as much air is drawn out as possible by means of a pump. Ethylene oxide can then arrive from a gas storage vessel connected to the sterilisation chamber to replace the air drawn out. This gas remains mixed with the articles for the period which the sterilisation requires while taking account of the relative humidity, the pressure, the temperature, the gas density and the like. After that, the ethylene oxide is withdrawn from the sterilisation chamber and compressed in the abovementioned storage vessel. The air then enables it to replace the gas and the chamber opens. Advantages of the invention: use of the same quantity of gas an infinite number of times without any loss or leakage. No contamination of the surrounding air results therefrom. No danger of skin inflammation after the use of the gas. Possibility of a number of successive sterilisation operations without needing to wash the sterilisation chamber with inert gases.

Description

La presente invention concerne une nouvelle méthode de stérilisation de beaucoup d'articles médicaux, chirugicaux et pharmaceutiques, même ceux qui ne peuvent être stérilisés au moyen de l'autoclave. The present invention relates to a new method of sterilization of many medical, surgical and pharmaceutical articles, even those which cannot be sterilized by means of the autoclave.

Cette méthode se base sur le principe de l'évacuation de l'air suivie par le passage du gaz d'oxyde de l'éthylène mais dans un cycle clos. This method is based on the principle of air evacuation followed by the passage of ethylene oxide gas but in a closed cycle.

Le gaz d'oxyde de l'éthylène est considéré jusqu'aujourd'hui le meilleur gaz pour la stérilisation des objets, en raison de sa grande capacité de pénétration , sans laisser de traces nuisibles aux objets stérilisés. Ethylene oxide gas is considered to date the best gas for sterilizing objects, because of its great penetration capacity, without leaving harmful traces on sterilized objects.

Actuellement et dans tous les hopitaux modernes, il y a au moins un appareil de stérilisation à l'oxyde de l'éthylène. Mais la méthode actuelle de l'emploi de ce gaz a ses dangers, car aprés l'emploi de ce gaz , la chambre de stérilisation dans l'appareil stérilisateur, où l'oxyde de l'éthylène a circulé environ 4 heures, afin de stériliser les objets voulus cette chambre doit etre lavée avec des gaz inertes, inactifs durant une période de huit à douze heures , afin d'eliminer toute trace de ce gaz stérilisant, car il cause de graves inflamations de la peau.Currently and in all modern hospitals, there is at least one ethylene oxide sterilization device. But the current method of using this gas has its dangers, because after the use of this gas, the sterilization chamber in the sterilizer, where the ethylene oxide has circulated for about 4 hours, in order to sterilize the desired objects this chamber must be washed with inert, inactive gases for a period of eight to twelve hours, in order to remove all traces of this sterilizing gas, as it causes serious inflammation of the skin.

Par cette invention , l'oxyde d'éthylène passe à travers un cycle complètement clos, et par conséquent il est: - loin de tout contact avec la peau. By this invention, ethylene oxide goes through a completely closed cycle, and therefore it is: - far from any contact with the skin.

- garde l'atmosphère environant loin de toute polution resultant de toute
propagation de ce gaz
Autre avantage de cette invention:
Elle permet d'employer la même quantité de gaz un nombre infini de fois, tant qu'il n'y a pas eu de fuite de gaz , car le gaz va du reservoir à la chambre de stérilisation et retourne de la chambre de stérilisation au même reservoir sans aucune fuite ou perte.- keeps the surrounding atmosphere away from any pollution resulting from any
propagation of this gas
Another advantage of this invention:
It allows the same quantity of gas to be used an infinite number of times, as long as there has been no gas leak, because the gas goes from the reservoir to the sterilization chamber and returns from the sterilization chamber to same tank without any leakage or loss.

A quoi consiste cette nouvelle méthode ?
Cette nouvelle méthode de stérilisation consiste à mettre les articles à stériliser , soit enveloppés dans des enveloppes en plastic léger, soit non enveloppés, dans une chambre de stérilisation hermétiquement fermée de n'importe quelle forme ou n'importe quelle grandeur.What does this new method consist of?
This new method of sterilization consists of placing the articles to be sterilized, either wrapped in light plastic envelopes, or unwrapped, in a hermetically sealed sterilization chamber of any shape or size.

Au moyen d'une pompe aspirante refoulante''jointe à la chambre de stérilisation, -l'air est aspiré de la chambre de stérilisation et rejeté à l'exterieur, jusqu'à l'évacuation maximum de l'air à l'interieur de la chambre de stérilisation
D'un reservoir de gaz joint à la chambre de stérilisation, un gaz stérilisant " l'oxyde de l'éthylène " va automatiquement passer du reser voir à la chambre de stérilisation , à travers un robinet d'arrêt, comme résultat naturel de la difference de pression, aprés l'évacuation de l'air à l'interieur de la chambre , jusqu a ce que la pression du gaz à l'interieur de la chambre arrive à la pression voulue, tout en tenant compte des conditions générales de stérilisation: humidité relative, température, densité du gaz , .. etc. By means of a pressure suction pump '' attached to the sterilization chamber, - the air is sucked from the sterilization chamber and discharged outside, until the maximum evacuation of the air inside of the sterilization chamber
From a gas tank attached to the sterilization chamber, a sterilizing gas "ethylene oxide" will automatically pass from the reservoir to the sterilization chamber, through a shut-off valve, as a natural result of the pressure difference, after evacuation of the air inside the chamber, until the gas pressure inside the chamber reaches the desired pressure, while taking into account the general sterilization conditions : relative humidity, temperature, gas density, etc.

Le temps que passe l'oxyde de l'éthylène dans la chambre de stérilisation , mélangé et entourant les objets à stériliser, dépend de la densité du gaz, de la température à l'interieur de la chambre de stérilisation, de l'humidité relative. The time spent by the ethylene oxide in the sterilization chamber, mixed and surrounding the objects to be sterilized, depends on the density of the gas, the temperature inside the sterilization chamber, the relative humidity .

A la fin du temps demandé pour la stérilisation, l'oxyde de l'éthy- lène est d'abord retiré au maximum au moyen de la pompe aspirante refoulante mentionnée ci-dessus, puis pressé à l'interieur du susdit reservoir à gaz ensuite , à travers un second robinet d'arrêt , l'air atmosphérique exter ieur entre dans la chambre de stérilisation, jusqu'à ce que la pression de l'air y soit égale à la pression atmosphérique à l'exterieur
N.B. L'air atmosphérique qui vient remplacer . .. . l'oxyde de l'éthylène , doit passer , pour arriver à la chambre de stérilisation, à travers des filtres anti-bactériens , si les objets stérilisés doivent être conservés dans un milieu stérilisé
La porte de la chambre de stérilisation peut être alors ouverte et les articles stérilisés peuvent en être retirés.At the end of the time required for sterilization, the ethylene oxide is first removed as much as possible by means of the suction pump mentioned above, then pressed inside the above-mentioned gas tank. , through a second shut-off valve, the outside atmospheric air enters the sterilization chamber, until the air pressure there is equal to the outside atmospheric pressure
NB The atmospheric air which replaces. ... ethylene oxide, must pass, to reach the sterilization chamber, through anti-bacterial filters, if the sterilized objects must be kept in a sterilized medium
The door to the sterilization chamber can then be opened and the sterilized items can be removed.

Cette méthode permet non seulement de stériliser les objets qui ne peuvent être stérilisés au moyen de ia vapeur d'eau et la chaleur dans un aeclave, mais aussi elle permet d'utiliser la même quantité de gaz un nombre infini de fois. Elle empêche aussi la polution de l'air environnant en comparaison avec les méthodes traditionnelles de stérilisation avec le gaz d'oxyde de l'éthylène. This method not only sterilizes objects that cannot be sterilized by steam and heat in a tank, but also allows the same amount of gas to be used an infinite number of times. It also prevents pollution of the surrounding air compared to traditional methods of sterilization with ethylene oxide gas.

Cette invention est une nouvelle méthode de stérilisation et qui peut être industrialisée en n'importe quelle forme ou grandeur, en ntim- porte quelle matière s'accordant avec l'oxyde de l'éthylène
Cette méthode peut être aussi industrialisée pour la stérilisation des objets , durant le transport par bateaux, trains, véhicules, ou par tout autre moyen de transport maritime, terrestre ou aérien
Les dessins annéxés illustrent l'invention~. This invention is a new method of sterilization and can be industrialized in any shape or size, in any material which agrees with ethylene oxide
This method can also be industrialized for the sterilization of objects, during transport by boats, trains, vehicles, or by any other means of maritime, land or air transport.
The appended drawings illustrate the invention ~.

( la figure 1 représente les étapes de la mise en pratique de cette méthode) ( La figure 2 représente une démonstration d'une mise en pratique de cette méthode)
En référence à ces dessins, les objets à stériliser sont mis à ltinterieur de ls chambre de stérilisation { a porte (2) est ensuite hermétiquement fermée de façon à ne permettre aucune fuite d'air ou de gaz de l'interieur de la chambre de stérilisation.(Figure 1 shows the steps for putting this method into practice) (Figure 2 shows a demonstration of how to put this method into practice)
With reference to these drawings, the objects to be sterilized are placed inside the sterilization chamber. The door (2) is then hermetically closed so as to allow no leakage of air or gas from inside the sterilization.

Les robinets d'arrêt (9, 10, 11 ) fermés, et les robinets d'arrêt ( 5, 6, 7, 8 ) ouverts l'air est aspiré de l'interieur de la chambre de stérilisation (1) à travers les robinets d'arrêt (5, 6 ) au moyen d'une pompe aspirante refoulante (3) et rejeté à l'exterieur à travers les robinets (7, 8 ) pour arriver à l'évacuation maximum de l'air de la chambre(l)
Les robinets d'arrêt (6, 7, 8, 10, 11 ) fermés et les robinets (5, 9 ) ouverts, permettent à l'oxyde de l'éthylène de passer du reservoir à gaz (4) à la chambre de stérilisation (1) jusqu'à ce que la pression du gaz à l'interieur de la chambre de stérilisation (1) soit égale à la pression atmosphérique environante.L'oxyde de l'éthylène reste alors à l'interieur de la chambre de stérilisation (1) mélangé, se mêlant à et entourant les objets à stériliser tout le temps demandé pour la stérilisation
A la fin du temps demandé pour la stérilisation , et qui dépend de plusieurs conditions: genre du gaz utilisé, densité de ce gaz , l'humidité relative, la pression et la température à l'interieur de la chambre de stérilisation (1), et aprés avoir fermé les robinets d'arrêt (8,9,11) et ouvert les robinets d'arrêt ( 5, 6, 7, 10 ), l'oxyde de l'éthylène est d'abord retiré au maximum de la chambre de stérilisation (1) au moyen de la pompe aspirante refoulante (3) et pressé à l'interieur de son reservoir ( 4 ) , ensuite à travers des filtres anti-bactériens et par le robinet dtarrêt (11) ouvert, l'air atmosphérique entre automatiquement dans la chambre de stérilisation (1) jusqutàttaqpression de l'air à l'interieur de la chambre (1) soit égale à la pression atmosphérique naturelle
La porte (2) est alors ouverte et permet de retirer les objets stérilisés, sans aucun danger d'inflamation de la peau ou de polution de l'air environnant The shut-off valves (9, 10, 11) closed, and the shut-off valves (5, 6, 7, 8) open, the air is drawn from inside the sterilization chamber (1) through the shut-off valves (5, 6) by means of a suction suction pump (3) and discharged outside through the valves (7, 8) to achieve maximum evacuation of air from the chamber ( l)
The shut-off valves (6, 7, 8, 10, 11) closed and the valves (5, 9) open, allow the ethylene oxide to pass from the gas tank (4) to the sterilization chamber (1) until the gas pressure inside the sterilization chamber (1) is equal to the surrounding atmospheric pressure. The ethylene oxide then remains inside the sterilization chamber (1) mixed, mixing with and surrounding the objects to be sterilized all the time required for sterilization
At the end of the time required for sterilization, which depends on several conditions: type of gas used, density of this gas, relative humidity, pressure and temperature inside the sterilization chamber (1), and after closing the shut-off valves (8,9,11) and opening the shut-off valves (5, 6, 7, 10), the ethylene oxide is first removed as much as possible from the chamber sterilization (1) by means of the pressure suction pump (3) and pressed inside its reservoir (4), then through anti-bacterial filters and by the stop tap (11) open, atmospheric air automatically enters the sterilization chamber (1) until the air pressure inside the chamber (1) is equal to natural atmospheric pressure
The door (2) is then open and allows sterilized objects to be removed, without any danger of igniting the skin or polluting the surrounding air.

Claims (2)

REVENDICATIONS 1 )- Métnode de stérilisation de nombreux articles médicaux, chirugicaux et pnarmaceutiques, même de ceux qui ne peuvent être stérilisés au moyen de l'autoclave, caracterisée en ce qu'elle consiste à mettre les oDjets à steriliser dans une cnamDre ae stérilisation nérmétiquement fermée, puis au moyen d'une pompe aspirante-refoulante, jointe à la chambre de stérilisation, l'air en est aspire' et rejete' à l'exterieur, jusqu'à l'évacuation maximum de l'air à l'interieur de la chambre de stérilisation 1) - Method of sterilization of many medical, surgical and pharmaceutical articles, even those which cannot be sterilized by means of the autoclave, characterized in that it consists in putting the objects to be sterilized in a sterilized sterilization container , then by means of a suction-pressure pump, attached to the sterilization chamber, the air is sucked in and discharged outside, until the maximum evacuation of the air inside the sterilization chamber D'un réservoir à gaz joint à la chambre de stérilisation l'oxyde d'éthylène, va automatiouement passer à la cnamDre de stérilisation, comme résultat naturel de la difference de pression aprés l'évacuation ae l'air de l'interieur de la chambre de stérilisation ou l'oxyde d'éthylene reste le temps demandé pour la stérilisation des objets, ensuite de auoi il est retiré au maximum de la chambre de sterilisation, au moyen de la pompe aspirante-refoulante mentionnée ci-aessus puis pressé dans le meme reservoir à gaz From a gas tank attached to the sterilization chamber, the ethylene oxide will automatically pass to the sterilization sequence, as a natural result of the pressure difference after evacuating the air from the interior of the sterilization chamber where ethylene oxide remains the time required for sterilization of the objects, then from this it is removed as much as possible from the sterilization chamber, by means of the suction-pressure pump mentioned above and then pressed in the same gas tank Comme résultat de la difference ae pression, l'air atmospnerique exterieur entre automatiquement, à travers des filtres anti-Dactériens, dans la cnambre ne stérilisation, jusqu'à ce cue la pression de l'air à l'interieur ae la chambre de sterilisation soit égale à la pression atmosphérique exterieure As a result of the pressure difference, the outside atmospheric air automatically enters, through anti-bacterial filters, into the sterilization chamber, until the air pressure inside the sterilization chamber is equal to the external atmospheric pressure 2 )- utilisation ae la méthode de stérilisation aécrite dans la revendication (1) pour la stérilisation dans les differents moyens de transport terrestres, maritimes et aériens.  2) - use of the sterilization method described in claim (1) for sterilization in different means of land, sea and air transport.
FR8816628A 1988-12-16 1988-12-16 Method for sterilising many medical, surgical and pharmaceutical articles by the use of the removal of air followed by the flow of ethylene oxide in a closed cycle Pending FR2643818A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR8816628A FR2643818A1 (en) 1988-12-16 1988-12-16 Method for sterilising many medical, surgical and pharmaceutical articles by the use of the removal of air followed by the flow of ethylene oxide in a closed cycle

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8816628A FR2643818A1 (en) 1988-12-16 1988-12-16 Method for sterilising many medical, surgical and pharmaceutical articles by the use of the removal of air followed by the flow of ethylene oxide in a closed cycle

Publications (1)

Publication Number Publication Date
FR2643818A1 true FR2643818A1 (en) 1990-09-07

Family

ID=9373042

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8816628A Pending FR2643818A1 (en) 1988-12-16 1988-12-16 Method for sterilising many medical, surgical and pharmaceutical articles by the use of the removal of air followed by the flow of ethylene oxide in a closed cycle

Country Status (1)

Country Link
FR (1) FR2643818A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0448390A2 (en) * 1990-03-21 1991-09-25 The Kendall Company Treatment with flammable gas, such as sterilisation with ethylene oxide
CN111103135A (en) * 2019-12-05 2020-05-05 福建福清核电有限公司 Nuclear reactor hydrodynamic pressure type main pump mechanical seal reusability inspection method

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3549312A (en) * 1968-05-06 1970-12-22 Sybron Corp Process and apparatus for recovering sterilization gas for reuse
DE2434473A1 (en) * 1974-07-18 1976-01-29 Deutsche Feuerloescher Bauanst Disinfection of sensitive materials by gaseous agents - complete penetration of porous goods, absolute safety, gases recovered
FR2395031A1 (en) * 1977-06-24 1979-01-19 Kendall & Co STERILIZATION PROCESS OF SUCCESSIVE LOADS OF MATERIAL TO BE STERILIZED WITH A MIXTURE OF ETHYLENE OXIDE AND AN INERT GAS

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3549312A (en) * 1968-05-06 1970-12-22 Sybron Corp Process and apparatus for recovering sterilization gas for reuse
DE2434473A1 (en) * 1974-07-18 1976-01-29 Deutsche Feuerloescher Bauanst Disinfection of sensitive materials by gaseous agents - complete penetration of porous goods, absolute safety, gases recovered
FR2395031A1 (en) * 1977-06-24 1979-01-19 Kendall & Co STERILIZATION PROCESS OF SUCCESSIVE LOADS OF MATERIAL TO BE STERILIZED WITH A MIXTURE OF ETHYLENE OXIDE AND AN INERT GAS

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0448390A2 (en) * 1990-03-21 1991-09-25 The Kendall Company Treatment with flammable gas, such as sterilisation with ethylene oxide
EP0448390A3 (en) * 1990-03-21 1993-01-13 The Kendall Company Treatment with flammable gas, such as sterilisation with ethylene oxide
CN111103135A (en) * 2019-12-05 2020-05-05 福建福清核电有限公司 Nuclear reactor hydrodynamic pressure type main pump mechanical seal reusability inspection method

Similar Documents

Publication Publication Date Title
JP6389182B2 (en) Vacuum storage system
CA2252456C (en) Methods for treatment and disposal of regulated medical waste
US20070207054A1 (en) Sterilizing apparatus and method
US7727464B2 (en) Process for operating a packaging transport system
US7919043B2 (en) Methods for treating allograft products
FR2643818A1 (en) Method for sterilising many medical, surgical and pharmaceutical articles by the use of the removal of air followed by the flow of ethylene oxide in a closed cycle
JP4668453B2 (en) Autoclave equipment
EP1110559A2 (en) Method and system for disinfecting products by the use of gas under atmospheric pressure with pretreatment in vacuo
AU642999B2 (en) Method for sterilizing an enclosure with noncondensing hydrogen peroxide-containing gas
CN111789982A (en) Ethylene oxide sterilization process
US20120080118A1 (en) Apparatus and methods for treating allograft products
CN107320332B (en) Biomedical sample aseptic collection transport preserves composite bag and its application method
FR2476489A1 (en) METHOD AND APPARATUS FOR STERILIZING CONTACT LENSES
US2134924A (en) Method of achieving absolute sterilization
CN109289067B (en) Instrument sterilizer, instrument sterilization system and instrument sterilization method
AU722163B2 (en) Sterilization
JPH07313576A (en) Medical fluid-filling medical tool packed in sterilized condition
CN105195498B (en) medical waste treatment method and device
FR2941865A1 (en) Treating heat-sensitive and/or thermostable contaminated material, by introducing material in treatment chamber, in situ forming composition from carbon dioxide and sodium hydroxide, and contacting contaminated material with composition
JPS6041963Y2 (en) steam sterilizer
Gibson Processing urinary endoscopes in a low-temperature steam and formaldehyde autoclave.
JP3913812B2 (en) How to extend the life of cut flowers
JP3050533B2 (en) Sterilization method and sterilization device
JP3592391B2 (en) Heat sterilization method
CN208710516U (en) Biomedical sample aseptic collection transport saves composite bag

Legal Events

Date Code Title Description
TP Transmission of property