CN111789982A - Ethylene oxide sterilization process - Google Patents
Ethylene oxide sterilization process Download PDFInfo
- Publication number
- CN111789982A CN111789982A CN202010717562.3A CN202010717562A CN111789982A CN 111789982 A CN111789982 A CN 111789982A CN 202010717562 A CN202010717562 A CN 202010717562A CN 111789982 A CN111789982 A CN 111789982A
- Authority
- CN
- China
- Prior art keywords
- sterilization
- ethylene oxide
- sterilization cabinet
- cabinet
- paper
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/20—Gaseous substances, e.g. vapours
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/26—Accessories or devices or components used for biocidal treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/26—Accessories or devices or components used for biocidal treatment
- A61L2/28—Devices for testing the effectiveness or completeness of sterilisation, e.g. indicators which change colour
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01M—TESTING STATIC OR DYNAMIC BALANCE OF MACHINES OR STRUCTURES; TESTING OF STRUCTURES OR APPARATUS, NOT OTHERWISE PROVIDED FOR
- G01M3/00—Investigating fluid-tightness of structures
- G01M3/02—Investigating fluid-tightness of structures by using fluid or vacuum
- G01M3/26—Investigating fluid-tightness of structures by using fluid or vacuum by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors
- G01M3/32—Investigating fluid-tightness of structures by using fluid or vacuum by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors for containers, e.g. radiators
- G01M3/34—Investigating fluid-tightness of structures by using fluid or vacuum by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors for containers, e.g. radiators by testing the possibility of maintaining the vacuum in containers, e.g. in can-testing machines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/10—Apparatus features
- A61L2202/13—Biocide decomposition means, e.g. catalysts, sorbents
Abstract
The invention relates to an ethylene oxide sterilization process, which comprises the following steps: the method comprises the steps of putting products to be sterilized and ethylene oxide chemical indication labels into paper-plastic packaging bags together, packaging biological indicators into single paper-plastic packaging bags separately, sealing the packaged paper-plastic packaging bags and placing the paper-plastic packaging bags into a sterilization cabinet, sequentially carrying out leakage detection, heating and humidifying pretreatment, dosing and vacuumizing, sterilizing and residue removal analysis stages, closing a power switch of the sterilization cabinet after the residue removal analysis stage is finished, naturally cooling the products in the sterilization cabinet, opening a door of the sterilization cabinet, taking out the products, sequentially carrying out sterilization effect detection and ethylene oxide residue detection on the products. The process is simple to operate, process parameters are optimized, sterilization and analysis operations are performed in the sterilization cabinet, products do not need to be transferred into a thermal analysis room for analysis, the workload of operators is reduced, the analysis time is shortened, and the sterilization effect detection and the ethylene oxide residual quantity measurement both accord with the national standard.
Description
Technical Field
The invention belongs to the technical field of ethylene oxide sterilization, and particularly relates to an ethylene oxide sterilization process.
Background
Ethylene oxide is a broad-spectrum sterilizing agent, and can kill various microorganisms including spores, tubercle bacillus, bacteria, viruses, fungi and the like at normal temperature. The ethylene oxide gas has strong penetrability, and the sterilized object can be wrapped or integrally packaged. When ethylene oxide is used for sterilization, plastic, rubber and metal materials are not corroded, articles are not yellowed and embrittled, and the ethylene oxide sterilization device can be used for sterilization of articles which cannot be soaked in a disinfectant and cannot resist high temperature and the like. However, since ethylene oxide is a flammable and explosive gas, has carcinogenic toxicity, and is a central nerve inhibitor, it is necessary to thoroughly analyze and remove ethylene oxide remaining in a sterilization apparatus and on a product after sterilization in order to ensure the health of an operator. At present, after the sterilization, the ethylene oxide sterilization process in the prior art needs to transfer the product to a thermal desorption room for thermal desorption treatment, so that the operation is complex, the workload of operators is increased, the work efficiency is reduced, the desorption time is prolonged, and safety accidents are easily caused if the operation is improper.
Disclosure of Invention
The invention aims to provide an ethylene oxide sterilization process, which aims to solve the technical problems of complex operation, long analysis time and high safety risk of the ethylene oxide sterilization process in the prior art.
In order to solve the technical problems, the technical scheme adopted by the invention is as follows: an ethylene oxide sterilization process is provided, which comprises the following steps: the method comprises the steps of putting products to be sterilized and ethylene oxide chemical indication labels into paper-plastic packaging bags together, packaging biological indicators into single paper-plastic packaging bags separately, sealing the packaged paper-plastic packaging bags and placing the paper-plastic packaging bags into a sterilization cabinet, sequentially carrying out leakage detection, heating and humidifying pretreatment, dosing and vacuumizing, sterilizing and residue removal analysis stages, closing a power switch of the sterilization cabinet after the residue removal analysis stage is finished, naturally cooling the products in the sterilization cabinet, opening a door of the sterilization cabinet, taking out the products, sequentially carrying out sterilization effect detection and ethylene oxide residue detection on the products.
Preferably, the process specifically comprises the following steps: step (1): and (3) leakage detection: starting a water circulation type vacuum pump, carrying out vacuum pumping operation on the sterilization cabinet, maintaining the pressure for a certain time after the pressure in the sterilization cabinet is reduced to-10 Kpa, then closing the water circulation type vacuum pump, observing whether the pressure in the sterilization cabinet is obviously changed or not, so as to detect the tightness of the connection between a cabinet door of the sterilization cabinet and each pipeline, and if the pressure in the sterilization cabinet is not obviously changed, automatically entering a temperature-raising and humidifying pre-treatment stage by the system;
step (2): heating and humidifying pretreatment: starting a heating and moisturizing system to keep the temperature and the humidity in the sterilization cabinet within the ranges of 55-60 ℃ and 40-90% RH, wherein the heating and moisturizing time is 8-10h, and after the heating and moisturizing pretreatment is finished, entering a dosing and vacuumizing stage;
and (3): dosing and vacuumizing stage: starting a water circulation type vacuum pump, vacuumizing the sterilization cabinet, opening a valve on a medicine feeding port pipeline when the pressure in the sterilization cabinet is reduced to-60 Kpa, slowly opening an ethylene oxide gas bottle valve, converting liquid ethylene oxide into gaseous ethylene oxide after the temperature rise of a vaporization box, uniformly and slowly feeding the gaseous ethylene oxide into the sterilization cabinet, monitoring the pressure change in the inner container of the sterilization cabinet in real time during the medicine feeding process, ensuring that the inside of the sterilization cabinet is in a negative pressure state, closing the valve of the medicine feeding pipeline after the medicine feeding is finished, and automatically feeding the system into a sterilization stage;
and (4): and (3) a sterilization stage: sterilizing for 10-12h at 55-60 deg.C and 40-90% RH, and removing residue;
and (5): and a residue removal and analysis stage: after sterilization is finished, the heating and moisturizing system is closed, the water circulation type vacuum pump is started, the sterilization cabinet is vacuumized, when the internal pressure of the sterilization cabinet is reduced to a certain value, air filtered by the air filtering filter element is introduced into the sterilization cabinet, ethylene oxide gas in the liner is forcibly flushed by using the air, the vacuumizing-air introducing operation is circularly performed, and the gas extracted from the interior of the sterilization cabinet is decomposed by the decomposition box full of water and is converted into glycol to be discharged into the wastewater treatment pipeline;
and (6): and (3) detection of the sterilization effect: after the residue removing and resolving stage is completed, all paper-plastic packaging bags are taken out, the paper-plastic packaging bags of the biological indicators are opened, the inner glass tube is broken to enable bacterium liquid in the glass tube to be in full contact with bacterium slices below the glass tube, then the bacterium liquid is inserted into a biological reader for culture, one biological indicator which is not sterilized is taken out, the biological indicator is inserted into the biological reader for culture by the same method, color comparison is carried out after 48 hours, the sterilized biological indicators basically have no color change, and the color change of the non-sterilized biological indicators is large; opening a paper-plastic packaging bag in which a product is packaged, taking out the ethylene oxide chemical indicating label, and observing the color change condition of the ethylene oxide chemical indicating label, wherein the ethylene oxide chemical indicating label before sterilization is pink, and the ethylene oxide chemical indicating label after sterilization is blue;
and (7): and (3) detecting the residual amount of ethylene oxide on the product: and (3) opening the paper-plastic package, taking out the sterilized product, and putting the sterilized product into ethylene oxide residual quantity detection equipment for detection, wherein the residual quantity of ethylene oxide on the product is 0.3mg | g through detection.
Preferably, after the residue removing and analyzing stage is finished, the product is naturally cooled in the sterilization cabinet for 30 min.
Preferably, in the step (1), when the leakage detection is performed, the pressure holding time is 2 min.
Preferably, in the dosing process in the step (3), the pressure change in the inner container of the sterilization cabinet is monitored in real time, and the pressure in the sterilization cabinet is ensured to be-5 Kpa.
Preferably, in the step (5), when the internal pressure of the sterilization cabinet is reduced to-50 Kpa during the vacuumizing operation of the sterilization cabinet, air filtered by the air filtering element is introduced into the sterilization cabinet, and the number of times of the vacuumizing-air introducing cycle operation is 6.
Preferably, the analysis time in the residue discharge analysis stage in the step (5) is 1 to 5 hours.
Compared with the prior art, the invention has the following advantages: (1) sterilization and analysis operations are carried out in the sterilization cabinet, the product does not need to be transferred to a thermal analysis room for analysis treatment, the operation process is simplified, the workload of operators is reduced, the analysis time is shortened, the working efficiency is improved, and the sterilization effect detection and the ethylene oxide residue measurement both meet the national standard; (2) the ethylene oxide gas pumped out of the sterilization cabinet is firstly decomposed in the water solution of the circulating water type vacuum pump by adopting the circulating water type vacuum pump and then enters the ethylene oxide decomposition box for secondary decomposition, so that the ethylene oxide analysis effect is improved, and the analysis time is further shortened; (3) the ethylene oxide liquid in the ethylene oxide gas tank is vaporized into gas in the vaporization box through temperature rise operation, the ethylene oxide is liquefied and then is filled into the ethylene oxide gas tank, the volume of the ethylene oxide gas tank is reduced, the ethylene oxide gas tank is convenient to store, and the ethylene oxide gas tank is matched with the ethylene oxide vaporization box for use, the ethylene oxide vaporization box can rapidly vaporize the ethylene oxide liquid, and the sterilization effect is improved.
Detailed Description
The following examples are given for the detailed implementation and specific operation of the present invention, but the scope of the present invention is not limited to the following examples.
Example 1
The ethylene oxide sterilization process is provided and specifically comprises the following steps:
step (1): and (3) leakage detection: putting a product to be sterilized and an ethylene oxide chemical indication label into a paper-plastic packaging bag together, packaging a biological indicator into a single paper-plastic packaging bag separately, cutting the paper-plastic packaging bag according to the length of the packaged product and putting the paper-plastic packaging bag into the sealing edge of a full-automatic sealing machine, setting the temperature of the full-automatic sealing machine to be 180 ℃, carrying out sealing operation, after the sealing operation is finished, putting each paper-plastic packaging bag into a sterilization cabinet, starting a water circulation type vacuum pump, carrying out vacuumizing operation on the sterilization cabinet, maintaining the pressure for 2min after the pressure in the sterilization cabinet is reduced to-10 Kpa, then closing the water circulation type vacuum pump, observing whether the pressure in the sterilization cabinet has obvious change or not, and detecting the sealing performance of the connection of a door of the sterilization cabinet and each pipeline, wherein if the pressure in the sterilization cabinet has no obvious change, the system automatically enters a temperature-raising and humidifying pre-treatment;
step (2): heating and humidifying pretreatment: starting a heating and moisturizing system to keep the temperature and the humidity in the sterilization cabinet within the ranges of 55-60 ℃ and 40-90% RH, wherein the heating and moisturizing time is 8-10h, and after the heating and moisturizing pretreatment is finished, entering a dosing and vacuumizing stage;
and (3): dosing and vacuumizing stage: starting a water circulation type vacuum pump, vacuumizing the sterilization cabinet, opening a valve on a medicine feeding port pipeline when the pressure in the sterilization cabinet is reduced to-60 Kpa, slowly opening an ethylene oxide gas bottle valve, converting liquid ethylene oxide into gaseous ethylene oxide through the temperature rise effect of a vaporization box, enabling the gaseous ethylene oxide to uniformly and slowly enter the sterilization cabinet, monitoring the pressure change in the inner container of the sterilization cabinet in real time in the medicine feeding process, ensuring that the pressure in the sterilization cabinet is-5 Kpa, closing the valve of the medicine feeding pipeline after the medicine feeding is finished, detecting the pressure of the inner container by the sterilization cabinet under the control of an electric cabinet, setting a pressure value and detection time in system setting, and automatically entering the sterilization stage by the sterilization cabinet when the electric cabinet detects that the pressure value of the inner container is a set value, namely-5 Kpa;
and (4): and (3) a sterilization stage: sterilizing for 10-12h at 55-60 deg.C and 40-90% RH, and removing residue;
and (5): and a residue removal and analysis stage: after the sterilization is finished, the heating and moisture preserving system is closed, the water circulation type vacuum pump is started, the sterilization cabinet is vacuumized, when the internal pressure of the sterilization cabinet is reduced to-50 Kpa, introducing air filtered by the air filtering filter element into the sterilization cabinet, forcibly flushing ethylene oxide gas in the liner by using the air, accelerating the flow of the gas in the sterilization cabinet, quickly and cleanly removing residual ethylene oxide in the sterilization cabinet and on products, avoiding adverse effects caused by ethylene oxide residue, circularly performing vacuumizing-air introducing operation, wherein the times of vacuumizing-air introducing circular operation are 6 times, the analysis time of a residue removal analysis stage is 1-5h, the gas extracted from the sterilization cabinet is decomposed by a decomposition box filled with water and is converted into glycol to be discharged into a wastewater treatment pipeline, so as to prevent operators from being poisoned by contacting residual ethylene oxide or exploding by contacting residual ethylene oxide with open fire;
and (6): and (3) detection of the sterilization effect: after the residue removing and resolving stage is finished, naturally cooling the product in a sterilization cabinet for 30min, then opening a cabinet door, taking out all paper-plastic packaging bags, opening the biological indicator paper-plastic packaging bags, clamping and breaking the inner glass tube to enable bacterium liquid in the glass tube to be fully contacted with bacterium slices below the glass tube, then inserting the bacterium liquid into a biological reader for culture, then taking out a biological indicator which is not sterilized, inserting the biological indicator into the biological reader for culture by the same method, performing color comparison after 48 hours, wherein the sterilized biological indicator basically has no color change, and the color change of the non-sterilized biological indicator is large; opening a paper-plastic packaging bag in which a product is packaged, taking out the ethylene oxide chemical indicating label, and observing the color change condition of the ethylene oxide chemical indicating label, wherein the ethylene oxide chemical indicating label before sterilization is pink, and the ethylene oxide chemical indicating label after sterilization is blue;
and (7): and (3) detecting the residual amount of ethylene oxide on the product: and (3) opening the paper-plastic package, taking out the sterilized product, and putting the sterilized product into ethylene oxide residual quantity detection equipment for detection, wherein the residual quantity of ethylene oxide on the product is 0.3mg | g through detection.
The process is simple to operate, sterilization and analysis operations are carried out in the sterilization cabinet by optimizing process parameters, the product does not need to be transferred into a thermal analysis room for analysis treatment, the workload of operators is reduced, the residual quantity of ethylene oxide on the sterilized product is 0.3 mg/g, the analysis time of a residue discharge analysis stage is 1-5h, the sterilization effect detection and the ethylene oxide residual quantity measurement both accord with the national standard, the analysis time is shortened, and the working efficiency is improved.
What has been described above are merely some embodiments of the present invention. It will be apparent to those skilled in the art that various changes and modifications can be made without departing from the inventive concept thereof, and these changes and modifications can be made without departing from the spirit and scope of the invention.
Claims (7)
1. An ethylene oxide sterilization process is characterized in that: the method comprises the following steps: the method comprises the steps of putting products to be sterilized and ethylene oxide chemical indication labels into paper-plastic packaging bags together, packaging biological indicators into single paper-plastic packaging bags separately, sealing the packaged paper-plastic packaging bags and placing the paper-plastic packaging bags into a sterilization cabinet, sequentially carrying out leakage detection, heating and humidifying pretreatment, dosing and vacuumizing, sterilizing and residue removal analysis stages, closing a power switch of the sterilization cabinet after the residue removal analysis stage is finished, naturally cooling the products in the sterilization cabinet, opening a door of the sterilization cabinet, taking out the products, sequentially carrying out sterilization effect detection and ethylene oxide residue detection on the products.
2. The ethylene oxide sterilization process according to claim 1, characterized in that: the method specifically comprises the following steps:
step (1): and (3) leakage detection: starting a water circulation type vacuum pump, carrying out vacuum pumping operation on the sterilization cabinet, maintaining the pressure for a certain time after the pressure in the sterilization cabinet is reduced to-10 Kpa, then closing the water circulation type vacuum pump, observing whether the pressure in the sterilization cabinet is obviously changed or not, so as to detect the tightness of the connection between a cabinet door of the sterilization cabinet and each pipeline, and if the pressure in the sterilization cabinet is not obviously changed, automatically entering a temperature-raising and humidifying pre-treatment stage by the system;
step (2): heating and humidifying pretreatment: starting a heating and moisturizing system to keep the temperature and the humidity in the sterilization cabinet within the ranges of 55-60 ℃ and 40-90% RH, wherein the heating and moisturizing time is 8-10h, and after the heating and moisturizing pretreatment is finished, entering a dosing and vacuumizing stage;
and (3): dosing and vacuumizing stage: starting a water circulation type vacuum pump, vacuumizing the sterilization cabinet, opening a valve on a medicine feeding port pipeline when the pressure in the sterilization cabinet is reduced to-60 Kpa, slowly opening an ethylene oxide gas bottle valve, converting liquid ethylene oxide into gaseous ethylene oxide after the temperature rise of a vaporization box, uniformly and slowly feeding the gaseous ethylene oxide into the sterilization cabinet, monitoring the pressure change in the inner container of the sterilization cabinet in real time during the medicine feeding process, ensuring that the inside of the sterilization cabinet is in a negative pressure state, closing the valve of the medicine feeding pipeline after the medicine feeding is finished, and automatically feeding the system into a sterilization stage;
and (4): and (3) a sterilization stage: sterilizing for 10-12h at 55-60 deg.C and 40-90% RH, and removing residue;
and (5): and a residue removal and analysis stage: after sterilization is finished, the heating and moisturizing system is closed, the water circulation type vacuum pump is started, the sterilization cabinet is vacuumized, when the internal pressure of the sterilization cabinet is reduced to a certain value, air filtered by the air filtering filter element is introduced into the sterilization cabinet, ethylene oxide gas in the liner is forcibly flushed by using the air, the vacuumizing-air introducing operation is circularly performed, and the gas extracted from the interior of the sterilization cabinet is decomposed by the decomposition box full of water and is converted into glycol to be discharged into the wastewater treatment pipeline;
and (6): and (3) detection of the sterilization effect: after the residue removing and resolving stage is completed, all paper-plastic packaging bags are taken out, the paper-plastic packaging bags of the biological indicators are opened, the inner glass tube is broken to enable bacterium liquid in the glass tube to be in full contact with bacterium slices below the glass tube, then the bacterium liquid is inserted into a biological reader for culture, one biological indicator which is not sterilized is taken out, the biological indicator is inserted into the biological reader for culture by the same method, color comparison is carried out after 48 hours, the sterilized biological indicators basically have no color change, and the color change of the non-sterilized biological indicators is large; opening a paper-plastic packaging bag in which a product is packaged, taking out the ethylene oxide chemical indicating label, and observing the color change condition of the ethylene oxide chemical indicating label, wherein the ethylene oxide chemical indicating label before sterilization is pink, and the ethylene oxide chemical indicating label after sterilization is blue;
and (7): and (3) detecting the residual amount of ethylene oxide on the product: and (3) opening the paper-plastic package, taking out the sterilized product, and putting the sterilized product into ethylene oxide residual quantity detection equipment for detection, wherein the residual quantity of ethylene oxide on the product is 0.3mg | g through detection.
3. The ethylene oxide sterilization process according to claim 2, characterized in that: and after the residue removing and resolving stage is finished, naturally cooling the product in the sterilization cabinet for 30 min.
4. The ethylene oxide sterilization process according to claim 2, characterized in that: and (2) when the leakage detection is carried out in the step (1), the pressure maintaining time is 2 min.
5. The ethylene oxide sterilization process according to claim 2, characterized in that: and (4) in the dosing process in the step (3), monitoring the pressure change in the inner container of the sterilization cabinet in real time, and ensuring that the pressure in the sterilization cabinet is-5 Kpa.
6. The ethylene oxide sterilization process according to claim 2, characterized in that: and (5) when the sterilization cabinet is vacuumized in the step (5), when the internal pressure of the sterilization cabinet is reduced to-50 Kpa, introducing air filtered by the air filtering element into the sterilization cabinet, wherein the number of times of vacuumization-air introduction circulation operation is 6.
7. The ethylene oxide sterilization process according to claim 2, characterized in that: and (5) the analysis time of the residue discharge analysis stage in the step (5) is 1-5 h.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010717562.3A CN111789982A (en) | 2020-07-23 | 2020-07-23 | Ethylene oxide sterilization process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010717562.3A CN111789982A (en) | 2020-07-23 | 2020-07-23 | Ethylene oxide sterilization process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111789982A true CN111789982A (en) | 2020-10-20 |
Family
ID=72828563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010717562.3A Pending CN111789982A (en) | 2020-07-23 | 2020-07-23 | Ethylene oxide sterilization process |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN111789982A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112741910A (en) * | 2021-01-06 | 2021-05-04 | 张家港市嘉音卫生用品有限公司 | Mask sterilization system and sterilization method |
| CN112754087A (en) * | 2020-12-30 | 2021-05-07 | 张家港市嘉音卫生用品有限公司 | Production method of disposable medical mask |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999033494A2 (en) * | 1997-12-24 | 1999-07-08 | Alliedsignal Inc. | Method and apparatus for aerating chemically-sterilized articles |
| EP2158481A1 (en) * | 2007-06-15 | 2010-03-03 | American Sterilizer Company | Method and apparatus for removal of vaporized hydrogen peroxide from a region |
| CN102018970A (en) * | 2010-12-27 | 2011-04-20 | 杭州优尼克消毒设备有限公司 | Sterilization process and equipment of absorbable sutures |
| CN102743773A (en) * | 2012-07-19 | 2012-10-24 | 武健 | Ethylene oxide preheating, sterilization and resolution integrated cabinet and sterilizing method |
| CN105214126A (en) * | 2015-10-20 | 2016-01-06 | 杭州大地维康医疗环保有限公司 | Waste and old clothes processing method |
| CN208114832U (en) * | 2017-11-26 | 2018-11-20 | 北京白象新技术有限公司 | Steam sterilizing fast verification device containing Chemical indicative card and biological indicator |
| CN109806424A (en) * | 2019-03-22 | 2019-05-28 | 常熟荣瑞灭菌技术有限公司 | A kind of ethylene oxide sterilizing technique |
| CN111068086A (en) * | 2019-12-11 | 2020-04-28 | 吉林华碳科技发展有限公司 | Method for disinfecting environment-friendly medical material |
-
2020
- 2020-07-23 CN CN202010717562.3A patent/CN111789982A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999033494A2 (en) * | 1997-12-24 | 1999-07-08 | Alliedsignal Inc. | Method and apparatus for aerating chemically-sterilized articles |
| EP2158481A1 (en) * | 2007-06-15 | 2010-03-03 | American Sterilizer Company | Method and apparatus for removal of vaporized hydrogen peroxide from a region |
| CN102018970A (en) * | 2010-12-27 | 2011-04-20 | 杭州优尼克消毒设备有限公司 | Sterilization process and equipment of absorbable sutures |
| CN102743773A (en) * | 2012-07-19 | 2012-10-24 | 武健 | Ethylene oxide preheating, sterilization and resolution integrated cabinet and sterilizing method |
| CN105214126A (en) * | 2015-10-20 | 2016-01-06 | 杭州大地维康医疗环保有限公司 | Waste and old clothes processing method |
| CN208114832U (en) * | 2017-11-26 | 2018-11-20 | 北京白象新技术有限公司 | Steam sterilizing fast verification device containing Chemical indicative card and biological indicator |
| CN109806424A (en) * | 2019-03-22 | 2019-05-28 | 常熟荣瑞灭菌技术有限公司 | A kind of ethylene oxide sterilizing technique |
| CN111068086A (en) * | 2019-12-11 | 2020-04-28 | 吉林华碳科技发展有限公司 | Method for disinfecting environment-friendly medical material |
Non-Patent Citations (3)
| Title |
|---|
| （美）M.西蒂格编，张立言译: "《农药制造方法》", 31 March 1972, 燃料化学工业出版社 * |
| 沙丽艳主编，冯永莉副主编: "《医技科室管理规范与操作常规系列丛书 消毒供应中心管理规范与操作常规》", 31 January 2018, 北京：中国协和医科大学出版社 * |
| 马贤鹏编: "《现代药物制剂新技术丛书 预灌封注射剂技术与应用》", 30 April 2017, 上海：上海科学技术出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112754087A (en) * | 2020-12-30 | 2021-05-07 | 张家港市嘉音卫生用品有限公司 | Production method of disposable medical mask |
| CN112741910A (en) * | 2021-01-06 | 2021-05-04 | 张家港市嘉音卫生用品有限公司 | Mask sterilization system and sterilization method |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN207356290U (en) | A kind of ethylene oxide sterilizer | |
| CN111789982A (en) | Ethylene oxide sterilization process | |
| EP3243531B1 (en) | Apparatus and method for detecting moisture in a vacuum chamber | |
| US8163234B2 (en) | Method for characterizing biological indicators in sterilization processes and apparatus for the implementation thereof | |
| JPS62213757A (en) | Sterilizing method | |
| MX2017005477A (en) | Apparatus and method for detecting moisture in a vacuum chamber. | |
| CN113509744A (en) | Improved freeze concentration type ethylene oxide recycling system | |
| JP2021512644A (en) | A system for exposure to aerosol products and how to use that system to assess container integrity | |
| EP2139527B1 (en) | Quantitative liquid injection device of plasma sterilizer | |
| CN205814729U (en) | A kind of ozone sterilization-box under common temperature | |
| CN102633222A (en) | Anaerobic filling method and anaerobic filling machine | |
| CN214408906U (en) | Food autoclaving production detection device | |
| EP3694566A1 (en) | Method and apparatus for sterilizing endoscopes | |
| CN211318386U (en) | Resistance detector of hydrogen peroxide sterilization indicator | |
| CN212439499U (en) | Full-automatic ethylene oxide sterilization equipment | |
| CN210762309U (en) | Positive pressure storage device | |
| CN103411127B (en) | Accident chlorine recovery system | |
| CN106729816B (en) | Portable high-pressure steam sterilization pot | |
| CN112716021B (en) | Tobacco lamina warehousing system based on preprocessing technology and working method thereof | |
| CN101269225A (en) | High-density carbonic anhydride disinfection device and method for germicidal treatment | |
| CN213158046U (en) | Hydrogen peroxide steam sterilization device | |
| CN209014207U (en) | Ink leak examines tooling | |
| CN216746634U (en) | Package sealing performance detection system | |
| CN204379838U (en) | Waste textile mixing ozone and ultraviolet combined disinfection unit | |
| CN213102244U (en) | Nucleic acid extraction instrument, filtering device, biological safety cabinet and superclean bench |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20201020 |
|
| RJ01 | Rejection of invention patent application after publication |