FR2618073B1 - Comprimes de type a matrice hydrophile a base de salbutamol et leur procede de preparation - Google Patents
Comprimes de type a matrice hydrophile a base de salbutamol et leur procede de preparationInfo
- Publication number
- FR2618073B1 FR2618073B1 FR8710048A FR8710048A FR2618073B1 FR 2618073 B1 FR2618073 B1 FR 2618073B1 FR 8710048 A FR8710048 A FR 8710048A FR 8710048 A FR8710048 A FR 8710048A FR 2618073 B1 FR2618073 B1 FR 2618073B1
- Authority
- FR
- France
- Prior art keywords
- salbutamol
- hydrophilic matrix
- active principle
- preparation
- component
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- NDAUXUAQIAJITI-UHFFFAOYSA-N albuterol Chemical compound CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1 NDAUXUAQIAJITI-UHFFFAOYSA-N 0.000 title abstract 2
- 229960002052 salbutamol Drugs 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title 1
- 239000003085 diluting agent Substances 0.000 abstract 2
- 239000011159 matrix material Substances 0.000 abstract 2
- 230000008961 swelling Effects 0.000 abstract 2
- 239000007970 homogeneous dispersion Substances 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000002459 sustained effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8710048A FR2618073B1 (fr) | 1987-07-16 | 1987-07-16 | Comprimes de type a matrice hydrophile a base de salbutamol et leur procede de preparation |
| CA000571875A CA1330041C (fr) | 1987-07-16 | 1988-07-13 | Comprimes de type a matrice hydrophile a base de salbutamol et leur procede de preparation |
| AT88401846T ATE73324T1 (de) | 1987-07-16 | 1988-07-15 | Salbutamoltabletten mit hydrophiler matrix und verfahren zu ihrer herstellung. |
| JP63176872A JPS6434914A (en) | 1987-07-16 | 1988-07-15 | Tablet and manufacture |
| ES198888401846T ES2039285T3 (es) | 1987-07-16 | 1988-07-15 | Comprimidos del tipo con matriz hidrofila a base de salbutamol y su procedimiento de preparacion. |
| EP88401846A EP0299877B1 (fr) | 1987-07-16 | 1988-07-15 | Comprimés de type à matrice hydrophile à base de salbutamol et leur procédé de préparation |
| DE8888401846T DE3869002D1 (de) | 1987-07-16 | 1988-07-15 | Salbutamoltabletten mit hydrophiler matrix und verfahren zu ihrer herstellung. |
| US07/774,724 US5132116A (en) | 1987-07-16 | 1991-10-08 | Tablets of the hydrophilic matrix type based on salbutamol and a process for their preparation |
| GR920401095T GR3004752T3 (enExample) | 1987-07-16 | 1992-05-28 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8710048A FR2618073B1 (fr) | 1987-07-16 | 1987-07-16 | Comprimes de type a matrice hydrophile a base de salbutamol et leur procede de preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2618073A1 FR2618073A1 (fr) | 1989-01-20 |
| FR2618073B1 true FR2618073B1 (fr) | 1990-09-07 |
Family
ID=9353198
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8710048A Expired - Fee Related FR2618073B1 (fr) | 1987-07-16 | 1987-07-16 | Comprimes de type a matrice hydrophile a base de salbutamol et leur procede de preparation |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5132116A (enExample) |
| EP (1) | EP0299877B1 (enExample) |
| JP (1) | JPS6434914A (enExample) |
| AT (1) | ATE73324T1 (enExample) |
| CA (1) | CA1330041C (enExample) |
| DE (1) | DE3869002D1 (enExample) |
| ES (1) | ES2039285T3 (enExample) |
| FR (1) | FR2618073B1 (enExample) |
| GR (1) | GR3004752T3 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2666506A1 (fr) * | 1990-09-07 | 1992-03-13 | Pf Medicament | Comprime a liberation prolongee a base de 5-mononitrate d'isosorbide et son procede de preparation. |
| US5155383A (en) * | 1992-02-03 | 1992-10-13 | Motorola, Inc. | Circuit and method of resetting a master/slave flipflop |
| US5298261A (en) * | 1992-04-20 | 1994-03-29 | Oregon Freeze Dry, Inc. | Rapidly distintegrating tablet |
| DE4329794C2 (de) * | 1993-09-03 | 1997-09-18 | Gruenenthal Gmbh | Tramadolsalz enthaltende Arzneimittel mit verzögerter Wirkstofffreisetzung |
| US5773025A (en) * | 1993-09-09 | 1998-06-30 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems--amorphous drugs |
| US6726930B1 (en) | 1993-09-09 | 2004-04-27 | Penwest Pharmaceuticals Co. | Sustained release heterodisperse hydrogel systems for insoluble drugs |
| US5455046A (en) * | 1993-09-09 | 1995-10-03 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems for insoluble drugs |
| US5662933A (en) * | 1993-09-09 | 1997-09-02 | Edward Mendell Co., Inc. | Controlled release formulation (albuterol) |
| US6818229B1 (en) | 1993-09-20 | 2004-11-16 | Kos Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia |
| US6746691B2 (en) | 1993-09-20 | 2004-06-08 | Kos Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics |
| US6129930A (en) | 1993-09-20 | 2000-10-10 | Bova; David J. | Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night |
| US6676967B1 (en) | 1993-09-20 | 2004-01-13 | Kos Pharmaceuticals, Inc. | Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia |
| US6080428A (en) | 1993-09-20 | 2000-06-27 | Bova; David J. | Nicotinic acid compositions for treating hyperlipidemia and related methods therefor |
| EP0759745A4 (en) * | 1994-05-13 | 1997-11-19 | Smithkline Beecham Corp | METHOD AND COMPOSITION FOR INCREASING FIXATION OF CALCIUM |
| US5945125A (en) * | 1995-02-28 | 1999-08-31 | Temple University | Controlled release tablet |
| WO1997026865A1 (en) * | 1996-01-29 | 1997-07-31 | Edward Mendell Co., Inc. | Sustained release excipient |
| ATE417604T1 (de) | 1996-07-08 | 2009-01-15 | Penwest Pharmaceuticals Co | Matrix mit verzögerter freisetzung für hochdosierte unlösliche arzneistoffe |
| US6056977A (en) | 1997-10-15 | 2000-05-02 | Edward Mendell Co., Inc. | Once-a-day controlled release sulfonylurea formulation |
| IT1297461B1 (it) * | 1997-10-29 | 1999-12-17 | Ciocca Maurizio | Preparazione di compresse a rilascio controllato a base di complessi tra carragenano e farmaci basici solubili |
| BR0009437A (pt) * | 1999-03-31 | 2002-01-15 | Janssen Pharmaceutica Nv | Amido pré-gelatinizado em uma formulação de liberação controlada |
| CA2352211C (en) * | 1999-09-30 | 2009-03-24 | Edward Mendell Co., Inc. | Sustained release matrix systems for highly soluble drugs |
| JP2005515966A (ja) * | 2001-07-06 | 2005-06-02 | エンドー ファーマシューティカルズ, インコーポレイティド | 鎮痛薬としての使用のための6−ヒドロキシ−オキシモルホンの経口投与 |
| TWI338583B (en) * | 2004-05-20 | 2011-03-11 | Otsuka Pharma Co Ltd | Solid pharmaceutical formulation |
| PT1931346E (pt) * | 2005-09-09 | 2012-08-14 | Angelini Labopharm Llc | Composição de trazodona para administração uma vez por dia |
| BRPI0615860B8 (pt) * | 2005-09-09 | 2021-05-25 | Labopharm Barbados Ltd | composição farmacêutica de liberação prolongada monolítica sólida |
| US20070160960A1 (en) * | 2005-10-21 | 2007-07-12 | Laser Shot, Inc. | System and method for calculating a projectile impact coordinates |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1338235A (en) * | 1970-12-15 | 1973-11-21 | May & Baker Ltd | Azapurinones |
| US4369172A (en) * | 1981-12-18 | 1983-01-18 | Forest Laboratories Inc. | Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose |
| FR2525474A1 (fr) * | 1982-04-26 | 1983-10-28 | Roussel Uclaf | Nouvelle forme pharmaceutique orale de clometacine |
| FR2535202B1 (fr) * | 1982-11-03 | 1985-08-09 | Fabre Sa Pierre | Comprimes de theophylline a liberation controlee et leur procede de fabrication |
| WO1985004100A1 (en) * | 1984-03-21 | 1985-09-26 | American Home Products Corporation | Sustained release pharmaceutical capsules |
| GB8514665D0 (en) * | 1985-06-11 | 1985-07-10 | Eroceltique Sa | Oral pharmaceutical composition |
| GB8521494D0 (en) * | 1985-08-29 | 1985-10-02 | Zyma Sa | Controlled release tablet |
| GB8613689D0 (en) * | 1986-06-05 | 1986-07-09 | Euro Celtique Sa | Pharmaceutical composition |
| US4824677A (en) * | 1986-12-18 | 1989-04-25 | The Unjohn Company | Grooved tablet for fractional dosing of sustained release medication |
| DE3720757A1 (de) * | 1987-06-24 | 1989-01-05 | Bayer Ag | Dhp-manteltablette |
-
1987
- 1987-07-16 FR FR8710048A patent/FR2618073B1/fr not_active Expired - Fee Related
-
1988
- 1988-07-13 CA CA000571875A patent/CA1330041C/fr not_active Expired - Fee Related
- 1988-07-15 EP EP88401846A patent/EP0299877B1/fr not_active Expired - Lifetime
- 1988-07-15 DE DE8888401846T patent/DE3869002D1/de not_active Expired - Fee Related
- 1988-07-15 AT AT88401846T patent/ATE73324T1/de not_active IP Right Cessation
- 1988-07-15 JP JP63176872A patent/JPS6434914A/ja active Pending
- 1988-07-15 ES ES198888401846T patent/ES2039285T3/es not_active Expired - Lifetime
-
1991
- 1991-10-08 US US07/774,724 patent/US5132116A/en not_active Expired - Fee Related
-
1992
- 1992-05-28 GR GR920401095T patent/GR3004752T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE73324T1 (de) | 1992-03-15 |
| FR2618073A1 (fr) | 1989-01-20 |
| ES2039285T3 (es) | 1993-09-16 |
| GR3004752T3 (enExample) | 1993-04-28 |
| US5132116A (en) | 1992-07-21 |
| JPS6434914A (en) | 1989-02-06 |
| EP0299877A1 (fr) | 1989-01-18 |
| EP0299877B1 (fr) | 1992-03-11 |
| CA1330041C (fr) | 1994-06-07 |
| DE3869002D1 (de) | 1992-04-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |