FR2603279A1 - Benzyloxy-phenyl-oxazolidinones, procede de preparation et utilisation en therapeutique - Google Patents

Benzyloxy-phenyl-oxazolidinones, procede de preparation et utilisation en therapeutique

Info

Publication number
FR2603279A1
FR2603279A1 FR8612369A FR8612369A FR2603279A1 FR 2603279 A1 FR2603279 A1 FR 2603279A1 FR 8612369 A FR8612369 A FR 8612369A FR 8612369 A FR8612369 A FR 8612369A FR 2603279 A1 FR2603279 A1 FR 2603279A1
Authority
FR
France
Prior art keywords
alkyl
amino ethyl
iii
reaction
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8612369A
Other languages
English (en)
Other versions
FR2603279B1 (fr
Inventor
Philippe Dostert
Patrice Renaut
Marguerita Strolin-Benedetti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RECH IND
Recherches Industrielles SA
Original Assignee
RECH IND
Recherches Industrielles SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RECH IND, Recherches Industrielles SA filed Critical RECH IND
Priority to FR8612369A priority Critical patent/FR2603279B1/fr
Priority to ZA876485A priority patent/ZA876485B/xx
Priority to DE8787401965T priority patent/DE3779525T2/de
Priority to CA000546004A priority patent/CA1302422C/fr
Priority to AU77780/87A priority patent/AU7778087A/en
Priority to EP87401965A priority patent/EP0259228B1/fr
Priority to ES198787401965T priority patent/ES2031921T3/es
Priority to US07/092,126 priority patent/US4897409A/en
Priority to JP62221164A priority patent/JPS6363671A/ja
Publication of FR2603279A1 publication Critical patent/FR2603279A1/fr
Application granted granted Critical
Publication of FR2603279B1 publication Critical patent/FR2603279B1/fr
Priority to GR920401426T priority patent/GR3005082T3/el
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA PRESENTE INVENTION CONCERNE EN TANT QUE PRODUITS INDUSTRIELS NOUVEAUX : I LES BENZYLOXY-PHENYL-OXAZOLIOINONES DE FORMULE I : (CF DESSIN DANS BOPI) DANS LAQUELLE : - R REPRESENTE UN ATOME D'HALOGENE NOTAMMENT F, CL ET BR OU UN GROUPE ALKOXY EN C-C, - LE CARBONE ASYMETRIQUE DU CYCLE OXAZOLIDINONE A LA CONFIGURATION R ET L'AUTRE CARBONE ASYMETRIQUE A LA CONFIGURATION S, II LES RACEMIQUES COMPRENANT LE COMPOSE DEFINI PAR LA STRUCTURE DE FORMULE I ET SON ENANTIOMERE, ET III LEURS SELS D'ADDITION. CES PRODUITS SONT UTILES EN THERAPEUTIQUE EN TANT QU'AGENTS IMAO-B.
FR8612369A 1986-09-03 1986-09-03 Benzyloxy-phenyl-oxazolidinones, procede de preparation et utilisation en therapeutique Expired FR2603279B1 (fr)

Priority Applications (10)

Application Number Priority Date Filing Date Title
FR8612369A FR2603279B1 (fr) 1986-09-03 1986-09-03 Benzyloxy-phenyl-oxazolidinones, procede de preparation et utilisation en therapeutique
ZA876485A ZA876485B (en) 1986-09-03 1987-08-31 5-aminoethyloxazolidin-2-one derivatives,process for the preparation thereof and their therapeutic use
CA000546004A CA1302422C (fr) 1986-09-03 1987-09-02 Derives 5-aminoethyloxazolidin-2-one, procede pour leur preparation et leurutilisation therapeutique
AU77780/87A AU7778087A (en) 1986-09-03 1987-09-02 5-aminoethyloxazolidin-2-one derivatives
DE8787401965T DE3779525T2 (de) 1986-09-03 1987-09-02 5-aminomethyl-2-oxazolidinon-derivate, ihre herstellung und ihre anwendung in der heilkunde.
EP87401965A EP0259228B1 (fr) 1986-09-03 1987-09-02 Dérivés 5-aminoéthylés de l'oxazolidinone-2, leur procédé de préparation et leur application en thérapeutique
ES198787401965T ES2031921T3 (es) 1986-09-03 1987-09-02 Derivados 5-aminoetilados de la oxazolidinona-2, su procedimiento de fabricacion y su aplicacion terapeutica.
US07/092,126 US4897409A (en) 1986-09-03 1987-09-02 5-aminoethyloxazolidin-2-one derivatives
JP62221164A JPS6363671A (ja) 1986-09-03 1987-09-03 ５−アミノエチルオキサゾリジン−２−オン誘導体、その製法およびその治療的用途
GR920401426T GR3005082T3 (fr) 1986-09-03 1992-07-01

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8612369A FR2603279B1 (fr) 1986-09-03 1986-09-03 Benzyloxy-phenyl-oxazolidinones, procede de preparation et utilisation en therapeutique

Publications (2)

Publication Number Publication Date
FR2603279A1 true FR2603279A1 (fr) 1988-03-04
FR2603279B1 FR2603279B1 (fr) 1988-12-16

Family

ID=9338661

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8612369A Expired FR2603279B1 (fr) 1986-09-03 1986-09-03 Benzyloxy-phenyl-oxazolidinones, procede de preparation et utilisation en therapeutique

Country Status (3)

Country Link
JP (1) JPS6363671A (fr)
FR (1) FR2603279B1 (fr)
ZA (1) ZA876485B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0271077A (ja) * 1988-09-07 1990-03-09 Osaka Shosen Mitsui Senpaku Kk コンテナ用冷凍装置

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2428032A1 (fr) * 1978-06-09 1980-01-04 Delalande Sa Nouvelles oxazolidimones, oxazolidinethiones et pyrrolidinones, leur procede de preparation et leur application en therapeutique
FR2500450A1 (fr) * 1981-02-25 1982-08-27 Delalande Sa Nouveaux derives aminomethyl-5 oxazolidiniques, leur procede de preparation et leur application en therapeutique
FR2528046A1 (fr) * 1982-06-08 1983-12-09 Delalande Sa Derives de l'oxazolidinone-2 n-arylee optiquement actifs, inhibiteurs specifiques et reversibles de la monoamine oxydase de type b et leur procede de preparation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2428032A1 (fr) * 1978-06-09 1980-01-04 Delalande Sa Nouvelles oxazolidimones, oxazolidinethiones et pyrrolidinones, leur procede de preparation et leur application en therapeutique
FR2500450A1 (fr) * 1981-02-25 1982-08-27 Delalande Sa Nouveaux derives aminomethyl-5 oxazolidiniques, leur procede de preparation et leur application en therapeutique
FR2528046A1 (fr) * 1982-06-08 1983-12-09 Delalande Sa Derives de l'oxazolidinone-2 n-arylee optiquement actifs, inhibiteurs specifiques et reversibles de la monoamine oxydase de type b et leur procede de preparation

Also Published As

Publication number Publication date
FR2603279B1 (fr) 1988-12-16
JPS6363671A (ja) 1988-03-22
ZA876485B (en) 1988-02-29

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Legal Events

Date Code Title Description
TP Transmission of property
TP Transmission of property
ST Notification of lapse