FR2592883A1 - Derives de vinblastine et composition pharmaceutique les contenant - Google Patents

Derives de vinblastine et composition pharmaceutique les contenant

Info

Publication number
FR2592883A1
FR2592883A1 FR8600364A FR8600364A FR2592883A1 FR 2592883 A1 FR2592883 A1 FR 2592883A1 FR 8600364 A FR8600364 A FR 8600364A FR 8600364 A FR8600364 A FR 8600364A FR 2592883 A1 FR2592883 A1 FR 2592883A1
Authority
FR
France
Prior art keywords
pharmaceutical composition
composition containing
derivatives
vinblastine derivatives
vinblastine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8600364A
Other languages
English (en)
Other versions
FR2592883B1 (fr
Inventor
Andre Trouet
Jean-Paul Dejonghe
Marie-Paule Collard
Rao K S P Bhushana
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ire Celltarg SA
Original Assignee
Ire Celltarg SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ire Celltarg SA filed Critical Ire Celltarg SA
Priority to FR8600364A priority Critical patent/FR2592883B1/fr
Priority to JP62005876A priority patent/JPH075608B2/ja
Priority to US07/002,895 priority patent/US4831038A/en
Priority to EP87400058A priority patent/EP0233101A1/fr
Priority to CA000527266A priority patent/CA1335686C/fr
Publication of FR2592883A1 publication Critical patent/FR2592883A1/fr
Application granted granted Critical
Publication of FR2592883B1 publication Critical patent/FR2592883B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des dérivés de vinca (indole-dihydroindole)- -alcaloïde, caractérisés en ce qu'au moins en position C3 et/ou C4 se trouve une chaîne grasse comportant au moins 7 atomes de carbone aliphatique. Les dérivés selon la présente invention sont utiles comme médicaments.
FR8600364A 1986-01-13 1986-01-13 Derives de vinblastine et composition pharmaceutique les contenant Expired FR2592883B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR8600364A FR2592883B1 (fr) 1986-01-13 1986-01-13 Derives de vinblastine et composition pharmaceutique les contenant
JP62005876A JPH075608B2 (ja) 1986-01-13 1987-01-13 ビンブラスチン誘導体
US07/002,895 US4831038A (en) 1986-01-13 1987-01-13 Vinblastine derivatives and pharmaceutical composition containing them
EP87400058A EP0233101A1 (fr) 1986-01-13 1987-01-13 Dérivés de vinblastine et composition pharmaceutique les contenant
CA000527266A CA1335686C (fr) 1986-01-13 1987-01-13 Vinblastine et composition pharmaceutique les contenant

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8600364A FR2592883B1 (fr) 1986-01-13 1986-01-13 Derives de vinblastine et composition pharmaceutique les contenant

Publications (2)

Publication Number Publication Date
FR2592883A1 true FR2592883A1 (fr) 1987-07-17
FR2592883B1 FR2592883B1 (fr) 1988-09-16

Family

ID=9331035

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8600364A Expired FR2592883B1 (fr) 1986-01-13 1986-01-13 Derives de vinblastine et composition pharmaceutique les contenant

Country Status (1)

Country Link
FR (1) FR2592883B1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2626882A1 (fr) * 1988-02-08 1989-08-11 Ire Celltarg Sa Conjugues de derives de vinca comportant une chaine detergente en position c-3
EP1427407A2 (fr) * 2001-03-23 2004-06-16 Protarga Inc. Conjugues a base d'amines gras et d'agents pharmaceutiques

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1423107B1 (fr) 2001-03-23 2012-05-09 Luitpold Pharmaceuticals, Inc. Conjugues d'agents pharmaceutiques et d'alcools gras

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2400029A1 (fr) * 1977-08-08 1979-03-09 Lilly Co Eli Amides de leurosine, leuroformine, desacetyl-leurosine et desacetylleuroformine, et leur utilisation therapeutique
US4203898A (en) * 1977-08-29 1980-05-20 Eli Lilly And Company Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2400029A1 (fr) * 1977-08-08 1979-03-09 Lilly Co Eli Amides de leurosine, leuroformine, desacetyl-leurosine et desacetylleuroformine, et leur utilisation therapeutique
US4203898A (en) * 1977-08-29 1980-05-20 Eli Lilly And Company Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2626882A1 (fr) * 1988-02-08 1989-08-11 Ire Celltarg Sa Conjugues de derives de vinca comportant une chaine detergente en position c-3
EP0328446A1 (fr) * 1988-02-08 1989-08-16 La Region Wallonne Conjugués de dérivé de vinca comportant une chaine détergente en position C-3
US5024835A (en) * 1988-02-08 1991-06-18 Ire-Celltarg S.A. Conjugates of a vinca derivative carrying a detergent chain in the C-3 position
EP1427407A2 (fr) * 2001-03-23 2004-06-16 Protarga Inc. Conjugues a base d'amines gras et d'agents pharmaceutiques
EP1427407A4 (fr) * 2001-03-23 2005-05-11 Luitpold Pharm Inc Conjugues a base d'amines gras et d'agents pharmaceutiques

Also Published As

Publication number Publication date
FR2592883B1 (fr) 1988-09-16

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Legal Events

Date Code Title Description
ST Notification of lapse