FR2577557B1 - Peptides et derives peptidiques, leur preparation, leur utilisation en therapeutique et compositions pharmaceutiques les contenant - Google Patents
Peptides et derives peptidiques, leur preparation, leur utilisation en therapeutique et compositions pharmaceutiques les contenantInfo
- Publication number
- FR2577557B1 FR2577557B1 FR868602218A FR8602218A FR2577557B1 FR 2577557 B1 FR2577557 B1 FR 2577557B1 FR 868602218 A FR868602218 A FR 868602218A FR 8602218 A FR8602218 A FR 8602218A FR 2577557 B1 FR2577557 B1 FR 2577557B1
- Authority
- FR
- France
- Prior art keywords
- peptides
- preparation
- pharmaceutical compositions
- compositions containing
- therapeutic use
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70265185A | 1985-02-19 | 1985-02-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2577557A1 FR2577557A1 (fr) | 1986-08-22 |
FR2577557B1 true FR2577557B1 (fr) | 1990-05-11 |
Family
ID=24822094
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR868602218A Expired - Lifetime FR2577557B1 (fr) | 1985-02-19 | 1986-02-17 | Peptides et derives peptidiques, leur preparation, leur utilisation en therapeutique et compositions pharmaceutiques les contenant |
Country Status (7)
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5194588A (en) * | 1985-01-22 | 1993-03-16 | Ici Americas Inc. | Aminoalcohol intermediates for peptide derivatives |
GB8600263D0 (en) * | 1985-01-22 | 1986-02-12 | Ici America Inc | Peptide derivatives |
US5055450A (en) * | 1985-01-22 | 1991-10-08 | Ici Americas Inc. | Peptide derivatives |
US5496927A (en) * | 1985-02-04 | 1996-03-05 | Merrell Pharmaceuticals Inc. | Peptidase inhibitors |
US4882420A (en) * | 1985-04-19 | 1989-11-21 | The Upjohn Company | Dihalo-statine substituted renin inhibitors |
GB8613704D0 (en) * | 1986-06-05 | 1986-07-09 | Ici America Inc | Difluoro keto compounds |
GB8613703D0 (en) * | 1986-06-05 | 1986-07-09 | Ici America Inc | Difluoro peptide compounds |
GB8619182D0 (en) * | 1986-08-06 | 1986-09-17 | Sandoz Ltd | Peptides & derivatives |
NZ223148A (en) * | 1987-01-16 | 1989-10-27 | Merrell Dow Pharma | Peptide derivatives having peptidase inhibition activity |
US4855303A (en) * | 1987-07-01 | 1989-08-08 | Pfizer Inc. | Fluorine containing renin inhibitors |
US5071837A (en) * | 1990-11-28 | 1991-12-10 | Warner-Lambert Company | Novel renin inhibiting peptides |
US5559140A (en) * | 1991-01-02 | 1996-09-24 | Merrell Pharmaceuticals Inc. | Difluoro statone analogs |
CA2098020C (en) * | 1991-01-02 | 2003-10-21 | Daniel Schirlin | Anti-viral compounds |
IL108031A0 (en) * | 1992-12-22 | 1994-04-12 | Procter & Gamble | Difluoro pentapeptide derivatives and pharmaceutical compositions containing them |
AU667995B2 (en) * | 1993-02-15 | 1996-04-18 | Bayer Aktiengesellschaft | New pseudopeptides having an antiviral action |
EP0707564B1 (en) * | 1993-07-08 | 2000-09-20 | Merrell Pharmaceuticals Inc. | Difluoro statone analogs |
KR100308839B1 (ko) * | 1993-09-09 | 2002-10-04 | 메렐 파마슈티칼스 인크. | 디플루오로 스타톤 항바이러스성 유사체 |
WO1995021186A1 (en) * | 1994-02-04 | 1995-08-10 | Merrell Pharmaceuticals Inc. | Macrocyclic difluorostatone derivatives useful as antiviral agents |
GB9502152D0 (en) * | 1995-02-03 | 1995-03-29 | Zeneca Ltd | Proline derivatives |
US6114380A (en) * | 1995-12-18 | 2000-09-05 | Merrell Pharmaceuticals Inc. | Difluoro statone analogs |
US8324347B2 (en) * | 2009-02-24 | 2012-12-04 | Institute For Systems Biology | Methods of using halogenated peptides as internal standards for liquid chromatography-mass spectrometry |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2424253A1 (fr) * | 1978-04-27 | 1979-11-23 | Brun Lab Sa Le | Nouveaux derives de peptides analogues des enkephalines, leur procede de preparation et leur application therapeutique |
EP0048159A3 (en) * | 1980-09-17 | 1982-05-12 | University Of Miami | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents |
EP0218688B1 (en) * | 1985-04-19 | 1990-09-12 | The Upjohn Company | Dihalo-statine substituted renin inhibitors |
-
1986
- 1986-02-11 CH CH537/86A patent/CH672792A5/de not_active IP Right Cessation
- 1986-02-13 DE DE19863604510 patent/DE3604510A1/de not_active Withdrawn
- 1986-02-17 BE BE1/011438A patent/BE904233A/fr not_active IP Right Cessation
- 1986-02-17 FR FR868602218A patent/FR2577557B1/fr not_active Expired - Lifetime
- 1986-02-17 GB GB08603835A patent/GB2171103B/en not_active Expired
- 1986-02-18 JP JP61034930A patent/JPS61194097A/ja active Pending
- 1986-02-18 IT IT47666/86A patent/IT1203743B/it active
Also Published As
Publication number | Publication date |
---|---|
FR2577557A1 (fr) | 1986-08-22 |
CH672792A5 (US07652060-20100126-C00012.png) | 1989-12-29 |
IT8647666A0 (it) | 1986-02-18 |
DE3604510A1 (de) | 1986-08-21 |
GB8603835D0 (en) | 1986-03-26 |
JPS61194097A (ja) | 1986-08-28 |
BE904233A (fr) | 1986-08-18 |
GB2171103A (en) | 1986-08-20 |
IT1203743B (it) | 1989-02-23 |
GB2171103B (en) | 1989-01-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |