FR2577225B1 - PEPTIDE DERIVATIVES INHIBITORS OF RENIN AND ACID PROTEASES - Google Patents

PEPTIDE DERIVATIVES INHIBITORS OF RENIN AND ACID PROTEASES

Info

Publication number
FR2577225B1
FR2577225B1 FR8501981A FR8501981A FR2577225B1 FR 2577225 B1 FR2577225 B1 FR 2577225B1 FR 8501981 A FR8501981 A FR 8501981A FR 8501981 A FR8501981 A FR 8501981A FR 2577225 B1 FR2577225 B1 FR 2577225B1
Authority
FR
France
Prior art keywords
renin
peptide derivatives
acid proteases
derivatives inhibitors
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8501981A
Other languages
French (fr)
Other versions
FR2577225A1 (en
Inventor
Jean Wagnon
Georges Callet
Jean Pierre Cagnol
Dino Nisato
Catherine Cazaubon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Priority to FR8501981A priority Critical patent/FR2577225B1/en
Priority to CA000500927A priority patent/CA1286846C/en
Priority to US06/826,375 priority patent/US4746648A/en
Priority to US06/826,349 priority patent/US4725580A/en
Priority to CA000501163A priority patent/CA1286847C/en
Priority to AU53272/86A priority patent/AU606312B2/en
Priority to AU53273/86A priority patent/AU606572B2/en
Priority to PT81990A priority patent/PT81990B/en
Priority to PT81991A priority patent/PT81991B/en
Priority to ZA86960A priority patent/ZA86960B/en
Priority to DE8686400272T priority patent/DE3671021D1/en
Priority to ZA86961A priority patent/ZA86961B/en
Priority to AT86400271T priority patent/ATE71111T1/en
Priority to DE8686400271T priority patent/DE3683170D1/en
Priority to EP86400271A priority patent/EP0192554B1/en
Priority to AT86400272T priority patent/ATE52518T1/en
Priority to DK64186A priority patent/DK64186A/en
Priority to EP86400272A priority patent/EP0193445B1/en
Priority to DK64086A priority patent/DK64086A/en
Priority to GR860398A priority patent/GR860398B/en
Priority to GR860399A priority patent/GR860399B/en
Priority to NZ215097A priority patent/NZ215097A/en
Priority to ES551820A priority patent/ES8701782A1/en
Priority to ES551821A priority patent/ES8701783A1/en
Priority to NZ215096A priority patent/NZ215096A/en
Priority to JP61028748A priority patent/JPS61186398A/en
Priority to JP61028747A priority patent/JPS61186397A/en
Publication of FR2577225A1 publication Critical patent/FR2577225A1/en
Application granted granted Critical
Publication of FR2577225B1 publication Critical patent/FR2577225B1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pyridine Compounds (AREA)
FR8501981A 1985-02-12 1985-02-12 PEPTIDE DERIVATIVES INHIBITORS OF RENIN AND ACID PROTEASES Expired FR2577225B1 (en)

Priority Applications (27)

Application Number Priority Date Filing Date Title
FR8501981A FR2577225B1 (en) 1985-02-12 1985-02-12 PEPTIDE DERIVATIVES INHIBITORS OF RENIN AND ACID PROTEASES
CA000500927A CA1286846C (en) 1985-02-12 1986-02-03 Peptide derivatives which inhibit renin and acid proteases
US06/826,375 US4746648A (en) 1985-02-12 1986-02-05 Peptide derivatives which inhibit renin and acid proteases
US06/826,349 US4725580A (en) 1985-02-12 1986-02-05 Peptide derivatives, analogous to pepstatin, which inhibit renin and acid proteases
CA000501163A CA1286847C (en) 1985-02-12 1986-02-05 Peptide derivatives analogous to pepstatin, which inhibit renin and acid proteases
AU53272/86A AU606312B2 (en) 1985-02-12 1986-02-06 Peptide derivatives which inhibit renin and acid proteases
AU53273/86A AU606572B2 (en) 1985-02-12 1986-02-06 Peptide derivatives, analogous to pepstatin, which inhibit renin and acid proteases.
PT81991A PT81991B (en) 1985-02-12 1986-02-07 PROCESS FOR THE PREPARATION OF PEPTIDIC DERIVATIVES, PEPESTATIN ANALOGS, DARENINE INHIBITORS AND ACID PROTEASES
PT81990A PT81990B (en) 1985-02-12 1986-02-07 PROCESS FOR THE PREPARATION OF PEPTIDIC DERIVATIVES INHIBITORS OF RENIN AND ACID PROTEASES
AT86400272T ATE52518T1 (en) 1985-02-12 1986-02-10 PEPTIDE DERIVATIVES, PEPSTATIN ANALOGUES, RENIN AND ACID PROTEASE INHIBITORS.
ZA86961A ZA86961B (en) 1985-02-12 1986-02-10 Peptide derivatives which inhibit renin and acid proteases
AT86400271T ATE71111T1 (en) 1985-02-12 1986-02-10 PEPTIDE DERIVATIVES, RENIN AND ACID PROTEASE INHIBITORS.
DE8686400271T DE3683170D1 (en) 1985-02-12 1986-02-10 PEPTIDE DERIVATIVES, RENINE AND ACID PROTEASE INHIBITING AGENTS.
EP86400271A EP0192554B1 (en) 1985-02-12 1986-02-10 Peptide derivatives inhibiting renin and acid proteases
ZA86960A ZA86960B (en) 1985-02-12 1986-02-10 Peptide derivatives,analogous to pepstatin,which inhibit renin and acid proteases
DK64186A DK64186A (en) 1985-02-12 1986-02-10 PEPTIDE DERIVATIVES
EP86400272A EP0193445B1 (en) 1985-02-12 1986-02-10 Peptide derivatives, pepstatin analogues, renin and acid-protease inhibitors
DK64086A DK64086A (en) 1985-02-12 1986-02-10 PEPTIDE DERIVATIVES
DE8686400272T DE3671021D1 (en) 1985-02-12 1986-02-10 PEPTIDE DERIVATIVES, PEPSTATINE ANALOG, RENINE AND ACID PROTEASE INHIBITING AGENTS.
GR860399A GR860399B (en) 1985-02-12 1986-02-11 Process for obtaining peptidic derivatives pepstatine analogs renines inhibitors and proteases acids
NZ215097A NZ215097A (en) 1985-02-12 1986-02-11 Peptide pepstatin analogues which inhibit renin and acid proteases
ES551820A ES8701782A1 (en) 1985-02-12 1986-02-11 Peptide derivatives inhibiting renin and acid proteases.
ES551821A ES8701783A1 (en) 1985-02-12 1986-02-11 Peptide derivatives inhibiting renin and acid proteases.
NZ215096A NZ215096A (en) 1985-02-12 1986-02-11 Renin inhibiting peptide derivatives, pepstatin analogues
GR860398A GR860398B (en) 1985-02-12 1986-02-11 Process for obtaining peptidic derivatives of renine inhibitors and proteases acids
JP61028748A JPS61186398A (en) 1985-02-12 1986-02-12 Pepstatin-analogue peptide derivative for controlling renninand acid protease
JP61028747A JPS61186397A (en) 1985-02-12 1986-02-12 Peptide derivative for controlling rennin and acid protease

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8501981A FR2577225B1 (en) 1985-02-12 1985-02-12 PEPTIDE DERIVATIVES INHIBITORS OF RENIN AND ACID PROTEASES

Publications (2)

Publication Number Publication Date
FR2577225A1 FR2577225A1 (en) 1986-08-14
FR2577225B1 true FR2577225B1 (en) 1987-08-28

Family

ID=9316186

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8501981A Expired FR2577225B1 (en) 1985-02-12 1985-02-12 PEPTIDE DERIVATIVES INHIBITORS OF RENIN AND ACID PROTEASES

Country Status (3)

Country Link
JP (2) JPS61186397A (en)
FR (1) FR2577225B1 (en)
ZA (2) ZA86961B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000004865A (en) * 1998-06-25 2000-01-11 Yasuyuki Moriyama Fire extinguishing apparatus attached to cigarette
JP2005075765A (en) * 2003-08-29 2005-03-24 Univ Of Tokyo New non-natural histidine analog amino acid

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2531951A1 (en) * 1982-08-17 1984-02-24 Sanofi Sa PEPTIDE DERIVATIVES INHIBITORS OF ACIDIC PROTEASES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM
DE3381565D1 (en) * 1982-12-27 1990-06-21 Merck & Co Inc RESPECTIVE TRIPEPTIDES.

Also Published As

Publication number Publication date
ZA86961B (en) 1986-10-29
ZA86960B (en) 1986-10-29
JPS61186398A (en) 1986-08-20
FR2577225A1 (en) 1986-08-14
JPS61186397A (en) 1986-08-20

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Legal Events

Date Code Title Description
ST Notification of lapse