FR2577226B1 - PEPSTATIN ANALOGS OF RENIN AND ACID PROTEASES - Google Patents

PEPSTATIN ANALOGS OF RENIN AND ACID PROTEASES

Info

Publication number
FR2577226B1
FR2577226B1 FR8501982A FR8501982A FR2577226B1 FR 2577226 B1 FR2577226 B1 FR 2577226B1 FR 8501982 A FR8501982 A FR 8501982A FR 8501982 A FR8501982 A FR 8501982A FR 2577226 B1 FR2577226 B1 FR 2577226B1
Authority
FR
France
Prior art keywords
pepstatin
renin
analogs
acid proteases
proteases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR8501982A
Other languages
French (fr)
Other versions
FR2577226A1 (en
Inventor
Jean Wagnon
Georges Callet
Catherine Cazaubon
Dino Nisato
Jean Pierre Cagnol
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Priority to FR8501982A priority Critical patent/FR2577226B1/en
Priority to CA000500927A priority patent/CA1286846C/en
Priority to US06/826,349 priority patent/US4725580A/en
Priority to CA000501163A priority patent/CA1286847C/en
Priority to US06/826,375 priority patent/US4746648A/en
Priority to AU53272/86A priority patent/AU606312B2/en
Priority to AU53273/86A priority patent/AU606572B2/en
Priority to PT81991A priority patent/PT81991B/en
Priority to PT81990A priority patent/PT81990B/en
Priority to EP86400272A priority patent/EP0193445B1/en
Priority to DE8686400272T priority patent/DE3671021D1/en
Priority to AT86400271T priority patent/ATE71111T1/en
Priority to DK64186A priority patent/DK64186A/en
Priority to EP86400271A priority patent/EP0192554B1/en
Priority to DE8686400271T priority patent/DE3683170D1/en
Priority to AT86400272T priority patent/ATE52518T1/en
Priority to DK64086A priority patent/DK64086A/en
Priority to GR860398A priority patent/GR860398B/en
Priority to GR860399A priority patent/GR860399B/en
Priority to ES551820A priority patent/ES8701782A1/en
Priority to NZ215097A priority patent/NZ215097A/en
Priority to NZ215096A priority patent/NZ215096A/en
Priority to ES551821A priority patent/ES8701783A1/en
Publication of FR2577226A1 publication Critical patent/FR2577226A1/en
Application granted granted Critical
Publication of FR2577226B1 publication Critical patent/FR2577226B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR8501982A 1985-02-12 1985-02-12 PEPSTATIN ANALOGS OF RENIN AND ACID PROTEASES Expired - Fee Related FR2577226B1 (en)

Priority Applications (23)

Application Number Priority Date Filing Date Title
FR8501982A FR2577226B1 (en) 1985-02-12 1985-02-12 PEPSTATIN ANALOGS OF RENIN AND ACID PROTEASES
CA000500927A CA1286846C (en) 1985-02-12 1986-02-03 Peptide derivatives which inhibit renin and acid proteases
US06/826,349 US4725580A (en) 1985-02-12 1986-02-05 Peptide derivatives, analogous to pepstatin, which inhibit renin and acid proteases
CA000501163A CA1286847C (en) 1985-02-12 1986-02-05 Peptide derivatives analogous to pepstatin, which inhibit renin and acid proteases
US06/826,375 US4746648A (en) 1985-02-12 1986-02-05 Peptide derivatives which inhibit renin and acid proteases
AU53272/86A AU606312B2 (en) 1985-02-12 1986-02-06 Peptide derivatives which inhibit renin and acid proteases
AU53273/86A AU606572B2 (en) 1985-02-12 1986-02-06 Peptide derivatives, analogous to pepstatin, which inhibit renin and acid proteases.
PT81990A PT81990B (en) 1985-02-12 1986-02-07 PROCESS FOR THE PREPARATION OF PEPTIDIC DERIVATIVES INHIBITORS OF RENIN AND ACID PROTEASES
PT81991A PT81991B (en) 1985-02-12 1986-02-07 PROCESS FOR THE PREPARATION OF PEPTIDIC DERIVATIVES, PEPESTATIN ANALOGS, DARENINE INHIBITORS AND ACID PROTEASES
EP86400271A EP0192554B1 (en) 1985-02-12 1986-02-10 Peptide derivatives inhibiting renin and acid proteases
AT86400271T ATE71111T1 (en) 1985-02-12 1986-02-10 PEPTIDE DERIVATIVES, RENIN AND ACID PROTEASE INHIBITORS.
DK64186A DK64186A (en) 1985-02-12 1986-02-10 PEPTIDE DERIVATIVES
EP86400272A EP0193445B1 (en) 1985-02-12 1986-02-10 Peptide derivatives, pepstatin analogues, renin and acid-protease inhibitors
DE8686400271T DE3683170D1 (en) 1985-02-12 1986-02-10 PEPTIDE DERIVATIVES, RENINE AND ACID PROTEASE INHIBITING AGENTS.
AT86400272T ATE52518T1 (en) 1985-02-12 1986-02-10 PEPTIDE DERIVATIVES, PEPSTATIN ANALOGUES, RENIN AND ACID PROTEASE INHIBITORS.
DK64086A DK64086A (en) 1985-02-12 1986-02-10 PEPTIDE DERIVATIVES
DE8686400272T DE3671021D1 (en) 1985-02-12 1986-02-10 PEPTIDE DERIVATIVES, PEPSTATINE ANALOG, RENINE AND ACID PROTEASE INHIBITING AGENTS.
GR860398A GR860398B (en) 1985-02-12 1986-02-11 Process for obtaining peptidic derivatives of renine inhibitors and proteases acids
GR860399A GR860399B (en) 1985-02-12 1986-02-11 Process for obtaining peptidic derivatives pepstatine analogs renines inhibitors and proteases acids
ES551820A ES8701782A1 (en) 1985-02-12 1986-02-11 Peptide derivatives inhibiting renin and acid proteases.
NZ215097A NZ215097A (en) 1985-02-12 1986-02-11 Peptide pepstatin analogues which inhibit renin and acid proteases
NZ215096A NZ215096A (en) 1985-02-12 1986-02-11 Renin inhibiting peptide derivatives, pepstatin analogues
ES551821A ES8701783A1 (en) 1985-02-12 1986-02-11 Peptide derivatives inhibiting renin and acid proteases.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8501982A FR2577226B1 (en) 1985-02-12 1985-02-12 PEPSTATIN ANALOGS OF RENIN AND ACID PROTEASES

Publications (2)

Publication Number Publication Date
FR2577226A1 FR2577226A1 (en) 1986-08-14
FR2577226B1 true FR2577226B1 (en) 1990-06-15

Family

ID=9316187

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8501982A Expired - Fee Related FR2577226B1 (en) 1985-02-12 1985-02-12 PEPSTATIN ANALOGS OF RENIN AND ACID PROTEASES

Country Status (1)

Country Link
FR (1) FR2577226B1 (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1245217A (en) * 1981-12-10 1988-11-22 Joshua S. Boger Renin inhibitory peptides having phe su13 xx deletion
FR2531951A1 (en) * 1982-08-17 1984-02-24 Sanofi Sa PEPTIDE DERIVATIVES INHIBITORS OF ACIDIC PROTEASES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM

Also Published As

Publication number Publication date
FR2577226A1 (en) 1986-08-14

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Legal Events

Date Code Title Description
ST Notification of lapse