FR2570376B1 - Nouveaux (isopropyl-5 (((methoxy-2 phenyl) piperazinyl)-2 ethoxy)-4 methyl-2 phenoxy)-1 alkylamino-3 propanols-2, leur methode de preparation et leur application therapeutique - Google Patents

Nouveaux (isopropyl-5 (((methoxy-2 phenyl) piperazinyl)-2 ethoxy)-4 methyl-2 phenoxy)-1 alkylamino-3 propanols-2, leur methode de preparation et leur application therapeutique

Info

Publication number
FR2570376B1
FR2570376B1 FR8414579A FR8414579A FR2570376B1 FR 2570376 B1 FR2570376 B1 FR 2570376B1 FR 8414579 A FR8414579 A FR 8414579A FR 8414579 A FR8414579 A FR 8414579A FR 2570376 B1 FR2570376 B1 FR 2570376B1
Authority
FR
France
Prior art keywords
propanols
piperazinyl
alkylamino
news
phenoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8414579A
Other languages
English (en)
Other versions
FR2570376A1 (fr
Inventor
Marie-Helene Creuzet
Claude Feniou
Francoise Guichard
Gisele Prat
Henri Pontagnier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cortial SA
Original Assignee
Cortial SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cortial SA filed Critical Cortial SA
Priority to FR8414579A priority Critical patent/FR2570376B1/fr
Priority to EP85450019A priority patent/EP0179009A1/fr
Priority to PT81139A priority patent/PT81139B/pt
Priority to JP60206177A priority patent/JPS6178777A/ja
Priority to OA58682BISD priority patent/OA08103A/fr
Priority to US06/777,530 priority patent/US4698343A/en
Priority to ES547126A priority patent/ES8605498A1/es
Priority to CA000491112A priority patent/CA1252465A/fr
Priority to ZA86718A priority patent/ZA86718B/xx
Publication of FR2570376A1 publication Critical patent/FR2570376A1/fr
Application granted granted Critical
Publication of FR2570376B1 publication Critical patent/FR2570376B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8414579A 1984-09-19 1984-09-19 Nouveaux (isopropyl-5 (((methoxy-2 phenyl) piperazinyl)-2 ethoxy)-4 methyl-2 phenoxy)-1 alkylamino-3 propanols-2, leur methode de preparation et leur application therapeutique Expired FR2570376B1 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
FR8414579A FR2570376B1 (fr) 1984-09-19 1984-09-19 Nouveaux (isopropyl-5 (((methoxy-2 phenyl) piperazinyl)-2 ethoxy)-4 methyl-2 phenoxy)-1 alkylamino-3 propanols-2, leur methode de preparation et leur application therapeutique
EP85450019A EP0179009A1 (fr) 1984-09-19 1985-09-02 Nouvelles n1-(aminoalcoxy)-4 isopropyl-5 phénoxy)-2 éthyl n4-phényl pipérazines, leur méthode de préparation et leur application thérapeutique
PT81139A PT81139B (pt) 1984-09-19 1985-09-17 Processo para a preparacao de novos derivados (2-alcoxi)fenilpiperazinicos
JP60206177A JPS6178777A (ja) 1984-09-19 1985-09-18 新規な（２‐アルコキシフエニル）ピペラジン誘導体，その製法及び治療上の応用
OA58682BISD OA08103A (fr) 1984-09-19 1985-09-19 Nouveaux dérivés (alcoxy-2) phénylpipéraziniques, leur méthode de préparation et leur application thérapeutique.
US06/777,530 US4698343A (en) 1984-09-19 1985-09-19 (Alkoxy-2)phenylpiperazines having alpha-1 and beta blocking properties
ES547126A ES8605498A1 (es) 1984-09-19 1985-09-19 Procedimiento de preparacion de nuevos derivados (2-alcoxi) fenilpiperazinicos y de sus sales de adicion acidas farma- ceuticamente aceptables
CA000491112A CA1252465A (fr) 1984-09-19 1985-09-19 Derives (alcoxy-2) phenylpiperaziniques, leur methode de preparation et leur application therapeutique
ZA86718A ZA86718B (en) 1984-09-19 1986-01-31 Novel bis(2-(4-hydroxy-2-isopropyl-5-methylphenoxy)ethyl)amines,the method of synthesis thereof,the pharmaceutical preparations containing them and their application in therapy

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8414579A FR2570376B1 (fr) 1984-09-19 1984-09-19 Nouveaux (isopropyl-5 (((methoxy-2 phenyl) piperazinyl)-2 ethoxy)-4 methyl-2 phenoxy)-1 alkylamino-3 propanols-2, leur methode de preparation et leur application therapeutique

Publications (2)

Publication Number Publication Date
FR2570376A1 FR2570376A1 (fr) 1986-03-21
FR2570376B1 true FR2570376B1 (fr) 1987-09-25

Family

ID=9307973

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8414579A Expired FR2570376B1 (fr) 1984-09-19 1984-09-19 Nouveaux (isopropyl-5 (((methoxy-2 phenyl) piperazinyl)-2 ethoxy)-4 methyl-2 phenoxy)-1 alkylamino-3 propanols-2, leur methode de preparation et leur application therapeutique

Country Status (2)

Country Link
JP (1) JPS6178777A (fr)
FR (1) FR2570376B1 (fr)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4202978A (en) * 1978-02-08 1980-05-13 Hoffmann-La Roche Inc. (S)-1-[2-(4-(2-Hydroxy-s-(1-alkylaminopropoxy)phenylalkyl]-4-phenylpiperazines
DE3264523D1 (en) * 1981-04-06 1985-08-08 Cortial Derivatives of 4-aminoethoxy-5-isopropyl-2-methyl phenol, process for their preparation and their use as medicines

Also Published As

Publication number Publication date
JPS6178777A (ja) 1986-04-22
FR2570376A1 (fr) 1986-03-21

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Legal Events

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