FR2569420B2 - Vecteur d'expression de l'hirudine, procede pour sa preparation par culture de cellules transformees et hirudine obtenue - Google Patents

Vecteur d'expression de l'hirudine, procede pour sa preparation par culture de cellules transformees et hirudine obtenue

Info

Publication number
FR2569420B2
FR2569420B2 FR8413250A FR8413250A FR2569420B2 FR 2569420 B2 FR2569420 B2 FR 2569420B2 FR 8413250 A FR8413250 A FR 8413250A FR 8413250 A FR8413250 A FR 8413250A FR 2569420 B2 FR2569420 B2 FR 2569420B2
Authority
FR
France
Prior art keywords
hirudin
culture
preparation
expression vector
transformed cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8413250A
Other languages
English (en)
Other versions
FR2569420A2 (fr
Inventor
Paul Tolstoshev
Richard Harvey
Michael Courtney
Jean-Pierre Lecocq
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Transgene SA
Original Assignee
Transgene SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR8413250A priority Critical patent/FR2569420B2/fr
Application filed by Transgene SA filed Critical Transgene SA
Priority to AT85400598T priority patent/ATE78294T1/de
Priority to EP85400598A priority patent/EP0158564B1/fr
Priority to DE8585400598T priority patent/DE3586333T2/de
Priority to CA000615690A priority patent/CA1341417C/fr
Priority to CA000477676A priority patent/CA1341414C/fr
Priority to PCT/FR1985/000062 priority patent/WO1985004418A1/fr
Priority to DK198505471A priority patent/DK175217B1/da
Publication of FR2569420A2 publication Critical patent/FR2569420A2/fr
Application granted granted Critical
Publication of FR2569420B2 publication Critical patent/FR2569420B2/fr
Priority to US08/481,867 priority patent/US5705355A/en
Priority to US08/500,111 priority patent/US5824505A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
FR8413250A 1984-03-27 1984-08-27 Vecteur d'expression de l'hirudine, procede pour sa preparation par culture de cellules transformees et hirudine obtenue Expired FR2569420B2 (fr)

Priority Applications (10)

Application Number Priority Date Filing Date Title
FR8413250A FR2569420B2 (fr) 1984-08-27 1984-08-27 Vecteur d'expression de l'hirudine, procede pour sa preparation par culture de cellules transformees et hirudine obtenue
EP85400598A EP0158564B1 (fr) 1984-03-27 1985-03-27 Vecteurs d'expression de l'hirudine, cellules transformées et procédé de préparation de l'hirudine
DE8585400598T DE3586333T2 (de) 1984-03-27 1985-03-27 Expressionsvektoren fuer hirudin, transformierte zellen und verfahren zur herstellung von hirudin.
CA000615690A CA1341417C (fr) 1984-03-27 1985-03-27 Vecteurs d'expression de l'hirudine, cellules transformees et procede de preparation de l'hirudine
AT85400598T ATE78294T1 (de) 1984-03-27 1985-03-27 Expressionsvektoren fuer hirudin, transformierte zellen und verfahren zur herstellung von hirudin.
CA000477676A CA1341414C (fr) 1984-03-27 1985-03-27 Vecteurs d'expression de l'hirudine, cellules transformees et procede de preparation de l'hirudine
PCT/FR1985/000062 WO1985004418A1 (fr) 1984-03-27 1985-03-27 Vecteurs d'expression de l'hirudine, cellules transformees et procede de preparation de l'hirudine
DK198505471A DK175217B1 (da) 1984-03-27 1985-11-26 Hirudinanalog, vektorer til ekspression af hirudinanalog, transformerede celler og fremgangsmåde til fremstilling af hirudinanalog
US08/481,867 US5705355A (en) 1984-03-27 1995-06-07 Hirudin, pharmaceutical compositions comprising it and their use
US08/500,111 US5824505A (en) 1984-03-27 1995-07-10 Vectors, transformed cells and process for the preparation of hirudin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8413250A FR2569420B2 (fr) 1984-08-27 1984-08-27 Vecteur d'expression de l'hirudine, procede pour sa preparation par culture de cellules transformees et hirudine obtenue

Publications (2)

Publication Number Publication Date
FR2569420A2 FR2569420A2 (fr) 1986-02-28
FR2569420B2 true FR2569420B2 (fr) 1988-02-12

Family

ID=9307231

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8413250A Expired FR2569420B2 (fr) 1984-03-27 1984-08-27 Vecteur d'expression de l'hirudine, procede pour sa preparation par culture de cellules transformees et hirudine obtenue

Country Status (1)

Country Link
FR (1) FR2569420B2 (fr)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2526661B1 (fr) * 1982-05-13 1986-02-21 Transgene Sa Nouveaux vecteurs d'expression de la proteine antigenique de la rage et leur application a la preparation de vaccins

Also Published As

Publication number Publication date
FR2569420A2 (fr) 1986-02-28

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Legal Events

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TP Transmission of property