FR2523305B1 - Dispositif pour mesurer la polarisation de fluorescence - Google Patents

Dispositif pour mesurer la polarisation de fluorescence

Info

Publication number
FR2523305B1
FR2523305B1 FR8221469A FR8221469A FR2523305B1 FR 2523305 B1 FR2523305 B1 FR 2523305B1 FR 8221469 A FR8221469 A FR 8221469A FR 8221469 A FR8221469 A FR 8221469A FR 2523305 B1 FR2523305 B1 FR 2523305B1
Authority
FR
France
Prior art keywords
fluorescence polarization
measuring fluorescence
measuring
polarization
fluorescence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8221469A
Other languages
English (en)
Other versions
FR2523305A1 (fr
Inventor
Wolfgang Eisert
Wolfgang Beisker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STRAHLEN UMWELTFORSCH GmbH
Original Assignee
STRAHLEN UMWELTFORSCH GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by STRAHLEN UMWELTFORSCH GmbH filed Critical STRAHLEN UMWELTFORSCH GmbH
Publication of FR2523305A1 publication Critical patent/FR2523305A1/fr
Application granted granted Critical
Publication of FR2523305B1 publication Critical patent/FR2523305B1/fr
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6445—Measuring fluorescence polarisation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/84—Preparation of the fraction to be distributed
    • G01N2030/8429—Preparation of the fraction to be distributed adding modificating material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/21—Polarisation-affecting properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/90—Plate chromatography, e.g. thin layer or paper chromatography
    • G01N30/92—Construction of the plate

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
FR8221469A 1982-03-12 1982-12-21 Dispositif pour mesurer la polarisation de fluorescence Expired FR2523305B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823208919 DE3208919A1 (de) 1982-03-12 1982-03-12 Anordnung zur messung der fluoreszenzpolarisation

Publications (2)

Publication Number Publication Date
FR2523305A1 FR2523305A1 (fr) 1983-09-16
FR2523305B1 true FR2523305B1 (fr) 1987-02-27

Family

ID=6157996

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8221469A Expired FR2523305B1 (fr) 1982-03-12 1982-12-21 Dispositif pour mesurer la polarisation de fluorescence

Country Status (5)

Country Link
US (1) US4548499A (fr)
JP (1) JPS58167944A (fr)
DE (1) DE3208919A1 (fr)
FR (1) FR2523305B1 (fr)
GB (1) GB2119924B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1376042A1 (ru) * 1985-05-12 1988-02-23 Институт физики АН БССР Лазерный флуориметрический детектор дл микроколоночной хроматографии
US4842404A (en) * 1988-01-13 1989-06-27 Ilc Technology, Inc. Dual detector laser beam power monitor
US5206699A (en) * 1988-05-06 1993-04-27 Gersan Establishment Sensing a narrow frequency band of radiation and gemstones
US5760900A (en) * 1989-03-18 1998-06-02 Canon Kabushiki Kaisha Method and apparatus for optically measuring specimen
JPH03140840A (ja) * 1989-10-26 1991-06-14 Hitachi Ltd 流動細胞分析装置
DE69028687T2 (de) * 1989-12-15 1997-04-10 Canon Kk Vorrichtung zur optischen Messung einer Probe
US5445935A (en) * 1992-11-23 1995-08-29 Royer; Catherine A. Quantitative detection of macromolecules with fluorescent oligonucleotides
DE19612569C1 (de) * 1996-03-29 1997-10-23 Palas Gmbh Verfahren und Vorrichtung zum Prüfen der Größenverteilung von Partikeln in Aerosolen
WO2001063260A1 (fr) * 2000-02-25 2001-08-30 Cambridge Research & Instrumentation Inc. Systeme de detection instantanee de la fluorescence dans deux bandes
AU2001250287B2 (en) * 2000-04-11 2005-06-23 Chemometec A/S Method and apparatus for detecting fluorescence of a sample
EP1676122A2 (fr) * 2003-09-30 2006-07-05 Singulex, Inc. Procedes pour ameliorer l'analyse de detection de particules
US20080021674A1 (en) * 2003-09-30 2008-01-24 Robert Puskas Methods for Enhancing the Analysis of Particle Detection
US6970241B1 (en) 2004-08-24 2005-11-29 Desa Richard J Device for enabling slow and direct measurement of fluorescence polarization
US20080225265A1 (en) * 2007-03-17 2008-09-18 Mi Research, Inc. Method and apparatus for finding macromolecule crystallization conditions
US8269191B2 (en) * 2010-11-05 2012-09-18 The United States Of America As Represented By The Secretary Of The Army System and method for measuring depolarization
DE102015007506B3 (de) * 2015-06-11 2016-12-15 Sensor Instruments Entwicklungs- Und Vertriebs Gmbh Vorrichtung und Verfahren zur Bestimmung einer Partikelgröße in einem Sprühstrahl
CN110927025B (zh) * 2019-12-05 2023-03-10 北京华泰诺安探测技术有限公司 一种气溶胶粒子监测设备

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL49622A0 (en) * 1976-05-21 1976-07-30 Elscint Ltd A method and apparatus for classifying biological cells
US4203670A (en) * 1977-04-21 1980-05-20 Bromberg Nathan S System and method of fluorescence polarimetry
DE2732272C2 (de) * 1977-07-16 1979-07-05 Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts, 6900 Heidelberg Verfahren und Vorrichtung zur Fluoreszenzanalyse von gefärbten Partikeln, insbesondere biologischen Zellen
DE2943116C2 (de) * 1979-10-25 1986-06-19 Gesellschaft für Strahlen- und Umweltforschung mbH, 8000 München Einrichtung zur durchflußcytometrischen Reaktions- und/oder Diffusionsmessung
US4419583A (en) * 1980-05-31 1983-12-06 Noeller Hans Guenter Polarization fluoroimmunoassay with pulsed light source

Also Published As

Publication number Publication date
GB8304977D0 (en) 1983-03-30
US4548499A (en) 1985-10-22
DE3208919C2 (fr) 1992-03-26
JPS58167944A (ja) 1983-10-04
DE3208919A1 (de) 1983-09-22
GB2119924A (en) 1983-11-23
GB2119924B (en) 1985-08-29
FR2523305A1 (fr) 1983-09-16

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Legal Events

Date Code Title Description
ST Notification of lapse