FR2487680A3 - Appts. for preparing therapeutic soln. for infusion - by piping solvent from one flask to second flask contg. therapeutic compound - Google Patents
Appts. for preparing therapeutic soln. for infusion - by piping solvent from one flask to second flask contg. therapeutic compound Download PDFInfo
- Publication number
- FR2487680A3 FR2487680A3 FR8017077A FR8017077A FR2487680A3 FR 2487680 A3 FR2487680 A3 FR 2487680A3 FR 8017077 A FR8017077 A FR 8017077A FR 8017077 A FR8017077 A FR 8017077A FR 2487680 A3 FR2487680 A3 FR 2487680A3
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- France
- Prior art keywords
- bottle
- flask
- solvent
- therapeutic
- needle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/201—Piercing means having one piercing end
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/2013—Piercing means having two piercing ends
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2068—Venting means
- A61J1/2075—Venting means for external venting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2079—Filtering means
- A61J1/2082—Filtering means for gas filtration
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
Description
La présente invention concerne un dispositif pour préparer un soluté thérapeutique, destiné à la perfusion. The present invention relates to a device for preparing a therapeutic solution, intended for infusion.
L'invention vise également le -procédé pour préparer un soluté thérapeutique, utilisant un tel dispositif. The invention also relates to the process for preparing a therapeutic solution, using such a device.
Pour préparer un soluté thérapeutique destiné à la perfusion, on est obligé de dissoudre ou de diluer un composé thérapeutique qui est conditionné dans un premier flacon, dans un solvant constitué en général par du sérum glucosé contenu dans un second flacon. To prepare a therapeutic solution intended for infusion, it is necessary to dissolve or dilute a therapeutic compound which is packaged in a first bottle, in a solvent generally consisting of glucose serum contained in a second bottle.
Dans le cas du traitement des affections hépatiques et surtout en cas de coma hépatique, le composé thérapeutique utilisé contient en général de l'oxoglurate d'arginine. In the case of the treatment of hepatic affections and especially in the event of hepatic coma, the therapeutic compound used generally contains arginine oxoglurate.
Ce produit est conditionné dans des flacons scellés, de faible capacité (inférieure à 100 ml). Le flacon contenant le sérum glucosé par contre, présente le volume habituel des flacons utilisés pour la perfusion, c'est-à-dire 250 ml. This product is packaged in sealed, small capacity bottles (less than 100 ml). The vial containing the glucose serum, on the other hand, presents the usual volume of the vials used for the infusion, that is to say 250 ml.
Pour préparer le soluté thérapeutique, ctest-à- dire dans le cas précité, une solution d'oxoglurate d'arginine dans du sérum glucosé, on procdde habituellement comme suit : on prélève avec une seringue 80 ml de sérum dans le flacon de 250 ml et on introduit la quantité ainsi prélevée dans le petit flacon contenant de l'oxoglurate d'arginine solide. On laisse ensuite dissoudre ce dernier dans le sérum glucosé, puis on prélève le soluté ainsi obtenu à la seringue. Le liquide ainsi prélevé est alors introduit dans le flacon de 250 ml contenant le sérum glucosé. To prepare the therapeutic solution, that is to say in the above-mentioned case, a solution of arginine oxoglurate in glucose serum, the usual procedure is as follows: 80 ml of serum is withdrawn from a 250 ml bottle with a syringe and the amount thus withdrawn is introduced into the small bottle containing solid arginine oxoglurate. The latter is then left to dissolve in the glucose serum, then the solute thus obtained is withdrawn with the syringe. The liquid thus withdrawn is then introduced into the 250 ml bottle containing the glucose serum.
Le prélèvement et l'introduction de liquide dans les deux flacons sont effectués de façon classique en enfonçant l'aiguille de la seringue dans les bouchons en caoutchouc qui obturent hermétiquement ces flacons. The withdrawal and the introduction of liquid into the two vials are carried out in a conventional manner by inserting the needle of the syringe into the rubber stoppers which hermetically seal these vials.
Ces opérations étant terminées, le flacon de 250 ml contenant le soluté thérapeutique ainsi préparé, peut être branché directement au patient en vue d'une perfusion intraveineuse. Once these operations have been completed, the 250 ml vial containing the therapeutic solution thus prepared can be connected directly to the patient for an intravenous infusion.
Cette façon de procéder présente des inconvénients. This procedure has drawbacks.
Elle comporte en effet de nombreuses manipulations et des risques non négligeables de contamination pouvant résulter de l'emploi de différentes seringues non parfaitement stériles.It indeed involves numerous manipulations and significant risks of contamination which may result from the use of different syringes which are not perfectly sterile.
Le but de la présente invention est de remédier aux inconvénients précités en créant un dispositif pour préparer un soluté thérapeutique, d'emploi particulièrement commode et évitant tout risque de contamination. The object of the present invention is to remedy the aforementioned drawbacks by creating a device for preparing a therapeutic solute, of particularly convenient use and avoiding any risk of contamination.
Le dispositif visé par l'invention comprend un premier flacon renfermant un composé thérapeutique et des moyens pour dissoudre et/ou diluer ce composé thérapeutique dans un solvant contenu dans un second flacon. The device targeted by the invention comprises a first bottle containing a therapeutic compound and means for dissolving and / or diluting this therapeutic compound in a solvent contained in a second bottle.
Suivant l'invention, ce dispositif est caractérisé en ce que les moyens précités comprennent un tube souple comportant à l'une de ses extrémités une aiguille à double canal destinée à être enfoncée dans le bouchon du flacon renfermant le solvant, l'un de ces canaux communiquant avec le tube souple et l'autre canal débouchant à l'exte- rieur au travers d'un filtre anti-bactérien, et en ce que ce tube souple comporte à son autre extrémité, une aiguille à canal unique, destinée à être enfoncée dans le bouchon du flacon renfermant le composé thérapeutique. According to the invention, this device is characterized in that the aforementioned means comprise a flexible tube comprising at one of its ends a double-channel needle intended to be pressed into the stopper of the vial containing the solvent, one of these channels communicating with the flexible tube and the other channel opening to the outside through an antibacterial filter, and in that this flexible tube comprises at its other end, a needle with a single channel, intended to be inserted into the stopper of the bottle containing the therapeutic compound.
Ce dispositif évite l'emploi de seringues et permet d'effectuer la préparation du soluté thérapeutique dans des conditions rigoureusement aseptiques. Pour faire cette préparation, il suffit en effet selon le procédé visé par l'invention, de connecter aux deux flacons la tubulure souple pourvue à ses extrémités d'aiguilles et de transvaser le solvant du flacon où il est contenu dans le flacon renfermant le produit à dissoudre. This device avoids the use of syringes and allows the preparation of the therapeutic solution to be carried out under strictly aseptic conditions. To make this preparation, it suffices in fact according to the process aimed by the invention, to connect to the two bottles the flexible tubing provided at its ends with needles and to transfer the solvent from the bottle where it is contained in the bottle containing the product. to dissolve.
Ce transvasement peut se faire simplement par gravité en soulevant et en renversant le flacon à solvant au-dessus de l'autre flacon. L'écoulement du solvant est possible grâce au canal relié à l'extérieur de l'aiguille qui est connectée au flacon à solvant. Du fait que ce canal débouche à l'extérieur par un filtre anti-bactérien, on évite toute contamination du produit. This transfer can be done simply by gravity by lifting and inverting the solvent bottle above the other bottle. Solvent flow is possible through the channel connected to the outside of the needle which is connected to the solvent vial. Because this channel opens to the outside through an anti-bacterial filter, any contamination of the product is avoided.
Une fois le transvasement terminé, le flacon contenant le composé thérapeutique dissous ou dilué dans le solvant peut être branché directement au malade, en vue de la perfusion. Once the transfer is complete, the vial containing the therapeutic compound dissolved or diluted in the solvent can be connected directly to the patient, for infusion.
D'autres particularités et avantages de l'invention apparaltront encore dans la description ci-après. Other features and advantages of the invention will become apparent in the description below.
Aux dessins annexés, donnés à titre d'exemples non limitatifs
- la figure 1 est une vue avec coupes longitudinales partielles, d'un dispositif conforme à l'invention branché entre deux flacons ;
- la figure 2 est une vue en coupe longitudinale à grande échelle, de l'aiguille à canal unique du dispositif
- la figure 3 est une vue en coupe longitudinale à grande échelle, de l'aiguille à double canal du dispositif
- la figure 4 est une vue analogue à la figure 1, montrant le dispositif en cours d'utilisation
- la figure 5 est une vue en plan d'une pince du dispositif.In the accompanying drawings, given by way of nonlimiting examples
- Figure 1 is a view with partial longitudinal sections, of a device according to the invention connected between two bottles;
- Figure 2 is a longitudinal sectional view on a large scale, of the single channel needle of the device
- Figure 3 is a longitudinal sectional view on a large scale, of the dual-channel needle of the device
- Figure 4 is a view similar to Figure 1, showing the device in use
- Figure 5 is a plan view of a clamp of the device.
Dans la réalisation de la figure 1, le dispositif 1 pour préparer un soluté thérapeutique est branché entre un flacon 2 contenant un solvant 3, par exemple du sérum glucosé et un flacon 4 contenant un composé thérapeutique solide 5, tel que de l'oxoglurate d'arginine. In the embodiment of FIG. 1, the device 1 for preparing a therapeutic solution is connected between a bottle 2 containing a solvent 3, for example glucose serum and a bottle 4 containing a solid therapeutic compound 5, such as oxoglurate d 'arginine.
Les flacons 2 et 4 ont des volumes égaux, correspondant au volume habituel de 250 ml des flacons destinés à la perfusion. Vials 2 and 4 have equal volumes, corresponding to the usual volume of 250 ml of the vials intended for infusion.
Les deux flacons 2 et 4 sont scellés dans des conditions aseptiques, au moyen de bouchons en caoutchouc 6, 7 sertis au col de ces flacons par des capsules déchirables 8, 9 en métal. The two bottles 2 and 4 are sealed under aseptic conditions, by means of rubber stoppers 6, 7 crimped to the neck of these bottles by tearable capsules 8, 9 made of metal.
Dans l'exemple considéré, le flacon 4 contient de l'oxoglurate d'arginine à l'état lyophilisé. Ce flacon 4 est scellé sous vide. Du fait de ce mode de fabrication, l'oxoglurate d'arginine forme une couche 5 qui est appliquée sur la quasi-totalité de la surface intérieure du flacon 4. In the example considered, the bottle 4 contains arginine oxoglurate in the lyophilized state. This bottle 4 is vacuum sealed. Due to this manufacturing method, arginine oxoglurate forms a layer 5 which is applied to almost the entire inner surface of the bottle 4.
Le dispositif 1 comprend un tube souple 10 en matière plastique, stérilisable, telle que du polychlorure de vinyle comportant à ses extrémités 10a, 10b, des aiguilles 11, 12 également en matière plastique stérilisable, enfoncées respectivement dans les bouchons 6 et 7 des flacons 2 et 4. The device 1 comprises a flexible tube 10 made of sterilizable plastic, such as polyvinyl chloride comprising at its ends 10a, 10b, needles 11, 12 also made of sterilizable plastic, inserted respectively in the caps 6 and 7 of the bottles 2 and 4.
L'aiguille 11 communique avec le tube souple 10 et avec l'intérieur du flacon 2 par un premier canal 13 (voir figure 3). Cette aiguille comporte un second canal 14 parallèle au premier canal qui communique avec l'intérieur du flacon 2 et débouche à l'extérieur au travers d'un filtre anti-bactérien 15. The needle 11 communicates with the flexible tube 10 and with the interior of the bottle 2 by a first channel 13 (see FIG. 3). This needle has a second channel 14 parallel to the first channel which communicates with the inside of the bottle 2 and opens to the outside through an anti-bacterial filter 15.
L'aiguille 12 communique avec le tube souple 10 et avec l'intérieur du flacon 4 par un canal unique 16 (voir figure 2). The needle 12 communicates with the flexible tube 10 and with the interior of the bottle 4 by a single channel 16 (see FIG. 2).
Chacune des aiguilles 11, 12, comporte une collerette 17, 18 pour faciliter l'enfoncement de ces aiguilles 11, 12 dans les bouchons respectifs 6 et 7 des flacons 2 et 4. Each of the needles 11, 12 has a flange 17, 18 to facilitate the insertion of these needles 11, 12 into the respective caps 6 and 7 of the bottles 2 and 4.
D'autre part, le tube souple 10 comporte une pince 19 en matière plastique (voir figure 5), servant si nécessaire à obturer ce tube 10 et à éviter de casser le vide du flacon 4 en cours de manipulation. On the other hand, the flexible tube 10 comprises a clamp 19 made of plastic material (see FIG. 5), serving if necessary to close this tube 10 and to avoid breaking the vacuum of the bottle 4 during handling.
Pour préparer un soluté thérapeutique à base d'oxoglurate d'arginine, au moyen du dispositif conforme à l'invention, en vue du traitement par perfusion d'un malade atteint d'une affection hépatique, on procède comme suit, selon le procédé de l'invention. To prepare a therapeutic solution based on arginine oxoglurate, using the device according to the invention, for the treatment by infusion of a patient suffering from a hepatic disease, the procedure is as follows, according to the method of the invention.
On commence tout d'abord par relier les deux flacons 2 et 4 par le tube souple 10 en enfonçant l'aiguille 11 à double canal dans le bouchon 6 du flacon 2 et l'aiguille 12 à canal unique dans le bouchon 7 du flacon 4. We start first by connecting the two bottles 2 and 4 by the flexible tube 10 by inserting the needle 11 with double channel in the stopper 6 of the bottle 2 and the needle 12 with single channel in the stopper 7 of the bottle 4 .
On soulève ensuite le flacon 2, au-dessus du flacon 4, comme indique sur la figure 4, puis on le renverse (voir flèche F). Then lift the bottle 2, above the bottle 4, as shown in Figure 4, then invert it (see arrow F).
Le sérum glucosé 3 s'écoule alors dans le flacon 4, par gravité en passant par le tube souple 10. Cet écoulement est possible grâce au canal 14 de mise à l'air libre de l'aiguille 11 et au vidé réalisé dans le flacon 4. The glucose serum 3 then flows into the bottle 4, by gravity passing through the flexible tube 10. This flow is possible thanks to the channel 14 for venting the needle 11 and the emptying produced in the bottle 4.
L'oxoglurate d'arginine se dissout dans le sérum glucosé. Cette dissolution est favorisée par le fait que l'oxuglurate d'arginine est réparti sur les parois du flacon 4. Arginine oxoglurate dissolves in glucose serum. This dissolution is favored by the fact that the arginine oxuglurate is distributed over the walls of the bottle 4.
Une fois l'écoulement et la dissolution terminés, le flacon 4 contenant le soluté d'oxoglurate d'arginine peut être branché directement au patient en vue de la perfusion. Once the flow and dissolution have been completed, the vial 4 containing the arginine oxoglurate solute can be connected directly to the patient for the infusion.
La préparation d'un soluté thérapeutique, au moyen du dispositif conforme à l'invention, est particulièrement commode et rapide. De plus, cette préparation est réalisée dans des conditions d'asepsie totale. En effet, lors des manipulations, le sérum glucosé et le composé thérapeutique ne risquent à aucun moment d'être en contact direct avec l'extérieur. The preparation of a therapeutic solution, using the device according to the invention, is particularly convenient and rapid. In addition, this preparation is carried out under conditions of total asepsis. In fact, during handling, the glucose serum and the therapeutic compound are never at risk of being in direct contact with the outside.
Le dispositif conforme à l'invention, constitué par la tubulure souple 10 équipée de ses deux aiguilles 11 et 12, grâce à sa simplicité de réalisation et par suite, de son faible coût, peut être jeté après chaque usage. On supprime ainsi l'opération longue et fastidieuse de stérilisation de la seringue avant l'emploi. The device according to the invention, constituted by flexible tubing 10 equipped with its two needles 11 and 12, thanks to its simplicity of construction and consequently, its low cost, can be discarded after each use. This eliminates the long and tedious operation of sterilizing the syringe before use.
Ainsi, chaque flacon 4 scellé sous vide comportant le composé thérapeutique 5 peut être commercialisé dans un emballage renfermant un dispositif conforme à l'invention prévu pour être utilisé avec ce flacon. Thus, each vacuum-sealed bottle 4 comprising the therapeutic compound 5 can be sold in a package containing a device according to the invention intended to be used with this bottle.
Bien entendu, l'invention n'est pas limitée à l'exemple que l'on vient de décrire et on peut apporter à celui-ci de nombreuses modifications, sans sortir du cadre de l'invention. Of course, the invention is not limited to the example which has just been described and many modifications can be made to it, without departing from the scope of the invention.
Ainsi, le dispositif conforme à l'invention peut être utilisé pour préparer des solutés thérapeutiques renfermant des composés thérapeutiques autres que l'oxoglurate d'arginine diouts dans un solvant qui peut être autre que du sérum glucosé. Thus, the device according to the invention can be used to prepare therapeutic solutes containing therapeutic compounds other than arginine oxouts diouts in a solvent which can be other than glucose serum.
Claims (7)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8017077A FR2487680A3 (en) | 1980-08-01 | 1980-08-01 | Appts. for preparing therapeutic soln. for infusion - by piping solvent from one flask to second flask contg. therapeutic compound |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8017077A FR2487680A3 (en) | 1980-08-01 | 1980-08-01 | Appts. for preparing therapeutic soln. for infusion - by piping solvent from one flask to second flask contg. therapeutic compound |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2487680A3 true FR2487680A3 (en) | 1982-02-05 |
| FR2487680B3 FR2487680B3 (en) | 1982-06-25 |
Family
ID=9244818
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8017077A Granted FR2487680A3 (en) | 1980-08-01 | 1980-08-01 | Appts. for preparing therapeutic soln. for infusion - by piping solvent from one flask to second flask contg. therapeutic compound |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2487680A3 (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0189549A2 (en) * | 1985-02-01 | 1986-08-06 | Ing. Erich Pfeiffer GmbH & Co. KG | Delivery device for free-flowing media |
| EP0197383A2 (en) * | 1985-04-10 | 1986-10-15 | Pfrimmer-Viggo GmbH + Co. KG | Method and device for the contamination-free mixing of fluids |
| WO1996026702A1 (en) * | 1995-03-02 | 1996-09-06 | Novo Nordisk A/S | Kit for storage and mixing of agents of which at least one is liquid |
| US5555920A (en) * | 1991-04-30 | 1996-09-17 | Automed Corporation | Method and apparatus for aliquotting blood serum or blood plasma |
| EP0757096A2 (en) * | 1995-07-29 | 1997-02-05 | Siemens Plc | Improvements in or relating to aqueous sample testing apparatus |
| EP1447072B1 (en) * | 2003-02-13 | 2011-07-27 | Becton Dickinson and Company | Method and device for transferring fluids between sampling tubes |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1223821A (en) * | 1958-08-04 | 1960-06-20 | Cutter Lab | Device for injecting solutions to a patient |
-
1980
- 1980-08-01 FR FR8017077A patent/FR2487680A3/en active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1223821A (en) * | 1958-08-04 | 1960-06-20 | Cutter Lab | Device for injecting solutions to a patient |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0189549A2 (en) * | 1985-02-01 | 1986-08-06 | Ing. Erich Pfeiffer GmbH & Co. KG | Delivery device for free-flowing media |
| EP0189549A3 (en) * | 1985-02-01 | 1987-08-19 | Ing. Erich Pfeiffer Gmbh & Co. Kg | Delivery device for free-flowing media |
| EP0197383A2 (en) * | 1985-04-10 | 1986-10-15 | Pfrimmer-Viggo GmbH + Co. KG | Method and device for the contamination-free mixing of fluids |
| EP0197383A3 (en) * | 1985-04-10 | 1987-11-11 | Pfrimmer-Viggo GmbH + Co. KG | Method and device for the contamination-free mixing of fluids |
| US5555920A (en) * | 1991-04-30 | 1996-09-17 | Automed Corporation | Method and apparatus for aliquotting blood serum or blood plasma |
| WO1996026702A1 (en) * | 1995-03-02 | 1996-09-06 | Novo Nordisk A/S | Kit for storage and mixing of agents of which at least one is liquid |
| US6021824A (en) * | 1995-03-02 | 2000-02-08 | Novo Nordisk A/S | Kit for storage and mixing of agents of which at least one is liquid |
| EP0757096A2 (en) * | 1995-07-29 | 1997-02-05 | Siemens Plc | Improvements in or relating to aqueous sample testing apparatus |
| EP0757096A3 (en) * | 1995-07-29 | 1997-03-05 | Siemens Plc | Improvements in or relating to aqueous sample testing apparatus |
| US5801052A (en) * | 1995-07-29 | 1998-09-01 | Siemens Plc | Aqueous sample testing apparatus |
| EP1447072B1 (en) * | 2003-02-13 | 2011-07-27 | Becton Dickinson and Company | Method and device for transferring fluids between sampling tubes |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2487680B3 (en) | 1982-06-25 |
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