FR2485540B1 - - Google Patents

Info

Publication number
FR2485540B1
FR2485540B1 FR8014512A FR8014512A FR2485540B1 FR 2485540 B1 FR2485540 B1 FR 2485540B1 FR 8014512 A FR8014512 A FR 8014512A FR 8014512 A FR8014512 A FR 8014512A FR 2485540 B1 FR2485540 B1 FR 2485540B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8014512A
Other languages
French (fr)
Other versions
FR2485540A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Priority to FR8014512A priority Critical patent/FR2485540A1/fr
Priority to GR65352A priority patent/GR75711B/el
Priority to GR65351A priority patent/GR75706B/el
Priority to DK283281A priority patent/DK283281A/da
Priority to EP81401027A priority patent/EP0044238B1/fr
Priority to DK283381A priority patent/DK283381A/da
Priority to EP81401028A priority patent/EP0043756B1/fr
Priority to AT81401028T priority patent/ATE7394T1/de
Priority to DE8181401027T priority patent/DE3162109D1/de
Priority to DE8181401028T priority patent/DE3163490D1/de
Priority to AT81401027T priority patent/ATE6066T1/de
Priority to NZ197563A priority patent/NZ197563A/xx
Priority to IE1452/81A priority patent/IE51358B1/en
Priority to NO812214A priority patent/NO812214L/no
Priority to NZ197564A priority patent/NZ197564A/xx
Priority to PT73283A priority patent/PT73283B/pt
Priority to ZA814394A priority patent/ZA814394B/xx
Priority to IE1453/81A priority patent/IE51359B1/en
Priority to NO812215A priority patent/NO159798C/no
Priority to ZA814392A priority patent/ZA814392B/xx
Priority to PT73284A priority patent/PT73284A/pt
Priority to JP10076481A priority patent/JPS5738785A/ja
Priority to JP10076581A priority patent/JPS5738786A/ja
Priority to CA000380874A priority patent/CA1175806A/en
Priority to CA000380872A priority patent/CA1173434A/en
Priority to MX10176881U priority patent/MX6880E/es
Priority to AU72411/81A priority patent/AU543165B2/en
Priority to ES503562A priority patent/ES8204996A1/es
Priority to AU72410/81A priority patent/AU7241081A/en
Priority to ES503563A priority patent/ES503563A0/es
Publication of FR2485540A1 publication Critical patent/FR2485540A1/fr
Priority to US06/525,797 priority patent/US4604387A/en
Application granted granted Critical
Publication of FR2485540B1 publication Critical patent/FR2485540B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds
    • A61K47/552—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds one of the codrug's components being an antibiotic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/555—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound pre-targeting systems involving an organic compound, other than a peptide, protein or antibody, for targeting specific cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8014512A 1980-06-30 1980-06-30 Nouveaux derives antibiotiques des cephalosporines, leur procede de preparation et les medicaments en contenant Granted FR2485540A1 (fr)

Priority Applications (31)

Application Number Priority Date Filing Date Title
FR8014512A FR2485540A1 (fr) 1980-06-30 1980-06-30 Nouveaux derives antibiotiques des cephalosporines, leur procede de preparation et les medicaments en contenant
GR65352A GR75711B (pt) 1980-06-30 1981-06-25
GR65351A GR75706B (pt) 1980-06-30 1981-06-25
EP81401027A EP0044238B1 (fr) 1980-06-30 1981-06-26 Dérivés de céphalosporines sulfoxydes, procédé de préparation et compositions pharmaceutiques en contenant
DK283381A DK283381A (da) 1980-06-30 1981-06-26 Fremgangsmaade til fremstilling af 1,2,4-triazinylthiomethyl-3-cephem-sulfoxid
EP81401028A EP0043756B1 (fr) 1980-06-30 1981-06-26 1,2,4-Triazinylthiométhyl-3-céphèmes sulfoxydes, procédé de préparation et compositions pharmaceutiques en contenant
AT81401028T ATE7394T1 (de) 1980-06-30 1981-06-26 1,2,4-triazinylthiomethyl-3-cephem-sulfoxyde, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate.
DE8181401027T DE3162109D1 (en) 1980-06-30 1981-06-26 Cephalosporin sulfoxides, process for their preparation and pharmaceutical compositions containing them
DE8181401028T DE3163490D1 (en) 1980-06-30 1981-06-26 1,2,4-triazinylthiomethyl-3-cephem sulfoxides, process for their preparation and pharmaceutical compositions containing them
AT81401027T ATE6066T1 (de) 1980-06-30 1981-06-26 Cephalosporinsulfoxyd-verbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate.
DK283281A DK283281A (da) 1980-06-30 1981-06-26 Fremgangsmaade til fremstilling af sulfoxidderivater af cephalosporiner
IE1453/81A IE51359B1 (en) 1980-06-30 1981-06-29 Derivatives of cephalosporin sulphoxides,process for their preparation and pharmaceutical compositions containing them
NO812214A NO812214L (no) 1980-06-30 1981-06-29 Fremgangsmaate for fremstilling av 3-(hydroksy-1,2,4-triazinyl)tiometyl-cefalosporiner
NZ197564A NZ197564A (en) 1980-06-30 1981-06-29 Cephalosporin sulphoxide derivatives and pharmaceutical compositions
PT73283A PT73283B (fr) 1980-06-30 1981-06-29 Procede de preparation d'oxides de cephalosporines
ZA814394A ZA814394B (en) 1980-06-30 1981-06-29 Derivatives of cephalosporine sulphoxides:preparation and pharmaceutical composition
NZ197563A NZ197563A (en) 1980-06-30 1981-06-29 3-(1,2,4-triazinylthiomethyl)-3-cephem-1-sulphoxide derivatives
NO812215A NO159798C (no) 1980-06-30 1981-06-29 Analogifremgangsmaate for fremstilling av terapeutisk aktive cefalosporin-oksyder.
ZA814392A ZA814392B (en) 1980-06-30 1981-06-29 1,2,4-triazinylthiomethyl-3-cepheme sulfoxide procedure for preparation and deledic forms
PT73284A PT73284A (fr) 1980-06-30 1981-06-29 Procede de preparation de derives de cephalosporines sulfoxides
IE1452/81A IE51358B1 (en) 1980-06-30 1981-06-29 1,2,4-triazinylthiomethyl-3-cephem sulfoxides,process for their preparation and pharmaceutical compositions containing them
AU72410/81A AU7241081A (en) 1980-06-30 1981-06-30 Cephalosporins
CA000380874A CA1175806A (en) 1980-06-30 1981-06-30 Derivatives of cephalosporine sulphoxides : preparation and pharmaceutical composition
CA000380872A CA1173434A (en) 1980-06-30 1981-06-30 1,2,4-triazinylthiomethyl-3-cepheme sulfoxide procedure for preparation and deledic forms
MX10176881U MX6880E (es) 1980-06-30 1981-06-30 Procedimiento de preparacion de 1,2,4-triaziniltiometil-3-cefem sulfoxidos
AU72411/81A AU543165B2 (en) 1980-06-30 1981-06-30 Cephalosporins
JP10076481A JPS5738785A (en) 1980-06-30 1981-06-30 3-(hydroxy-1,2,4-triazinyl)thiomethylcephalosporin , manufacture and drug composition containing same
JP10076581A JPS5738786A (en) 1980-06-30 1981-06-30 Cephalosporin sulfoxide derivative, manufacture and drug composition containing it
ES503563A ES503563A0 (es) 1980-06-30 1981-06-30 Procedimiento de preparacion de cefalosporinas oxidas
ES503562A ES8204996A1 (es) 1980-06-30 1981-06-30 Procedimiento de preparacion de 3-(1,2,4-hidroxitriazinil) tiometil cefalosporinas
US06/525,797 US4604387A (en) 1980-06-30 1983-08-23 1,2,4-triazinylthiomethyl-3-cephem sulfoxides, and a procedure for their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8014512A FR2485540A1 (fr) 1980-06-30 1980-06-30 Nouveaux derives antibiotiques des cephalosporines, leur procede de preparation et les medicaments en contenant

Publications (2)

Publication Number Publication Date
FR2485540A1 FR2485540A1 (fr) 1981-12-31
FR2485540B1 true FR2485540B1 (pt) 1984-02-24

Family

ID=9243670

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8014512A Granted FR2485540A1 (fr) 1980-06-30 1980-06-30 Nouveaux derives antibiotiques des cephalosporines, leur procede de preparation et les medicaments en contenant

Country Status (4)

Country Link
JP (2) JPS5738785A (pt)
AU (1) AU7241081A (pt)
FR (1) FR2485540A1 (pt)
ZA (2) ZA814392B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4367228A (en) * 1980-10-29 1983-01-04 Fujisawa Pharmaceutical Co., Ltd. Cephem compound and composition
DE3207840A1 (de) * 1982-03-04 1983-09-15 Hoechst Ag, 6230 Frankfurt "cephalosporinderivate und verfahren zu ihrer herstellung"
FR2546520B1 (fr) * 1983-05-27 1985-08-30 Sanofi Sa Nouveaux composes antibiotiques derives des cephalosporines
BRPI0413908A (pt) * 2003-08-25 2006-10-24 Revaax Pharmaceuticals Llc formulação farmacêutica neuroterapêutica em forma de dosagem oral, composto, e, método de tratamento de um distúrbio comportamental ou um distúrbio cognitivo

Also Published As

Publication number Publication date
JPS5738786A (en) 1982-03-03
FR2485540A1 (fr) 1981-12-31
AU7241081A (en) 1982-01-07
ZA814392B (en) 1982-07-28
JPS5738785A (en) 1982-03-03
ZA814394B (en) 1982-09-29

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Legal Events

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CA Change of address
CD Change of name or company name
TP Transmission of property
ST Notification of lapse