ZA814392B - 1,2,4-triazinylthiomethyl-3-cepheme sulfoxide procedure for preparation and deledic forms - Google Patents

1,2,4-triazinylthiomethyl-3-cepheme sulfoxide procedure for preparation and deledic forms

Info

Publication number
ZA814392B
ZA814392B ZA814392A ZA814392A ZA814392B ZA 814392 B ZA814392 B ZA 814392B ZA 814392 A ZA814392 A ZA 814392A ZA 814392 A ZA814392 A ZA 814392A ZA 814392 B ZA814392 B ZA 814392B
Authority
ZA
South Africa
Prior art keywords
triazinylthiomethyl
deledic
cepheme
sulfoxide
procedure
Prior art date
Application number
ZA814392A
Inventor
B Labeeuw
A Sahli
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of ZA814392B publication Critical patent/ZA814392B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds
    • A61K47/552—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds one of the codrug's components being an antibiotic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/555—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound pre-targeting systems involving an organic compound, other than a peptide, protein or antibody, for targeting specific cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA814392A 1980-06-30 1981-06-29 1,2,4-triazinylthiomethyl-3-cepheme sulfoxide procedure for preparation and deledic forms ZA814392B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8014512A FR2485540A1 (en) 1980-06-30 1980-06-30 Cephalosporin(s) active against gram-negative bacteria - are 7- 2-2-amino-4-thiazolyl 2-methoxy-imino acetamido 3 hydroxy-1,2,4-triazinyl-thiomethyl 3-cephem 4-carboxylic acid 1-S-oxide(s)

Publications (1)

Publication Number Publication Date
ZA814392B true ZA814392B (en) 1982-07-28

Family

ID=9243670

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA814394A ZA814394B (en) 1980-06-30 1981-06-29 Derivatives of cephalosporine sulphoxides:preparation and pharmaceutical composition
ZA814392A ZA814392B (en) 1980-06-30 1981-06-29 1,2,4-triazinylthiomethyl-3-cepheme sulfoxide procedure for preparation and deledic forms

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ZA814394A ZA814394B (en) 1980-06-30 1981-06-29 Derivatives of cephalosporine sulphoxides:preparation and pharmaceutical composition

Country Status (4)

Country Link
JP (2) JPS5738786A (en)
AU (1) AU7241081A (en)
FR (1) FR2485540A1 (en)
ZA (2) ZA814394B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4367228A (en) * 1980-10-29 1983-01-04 Fujisawa Pharmaceutical Co., Ltd. Cephem compound and composition
DE3207840A1 (en) * 1982-03-04 1983-09-15 Hoechst Ag, 6230 Frankfurt "CEPHALOSPORINE DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF"
FR2546520B1 (en) * 1983-05-27 1985-08-30 Sanofi Sa NOVEL ANTIBIOTIC COMPOUNDS DERIVED FROM CEPHALOSPORINS
WO2005020904A2 (en) * 2003-08-25 2005-03-10 Revaax Pharmaceuticals, Llc Oral neurotherapeutic cefazolin compositions

Also Published As

Publication number Publication date
JPS5738786A (en) 1982-03-03
FR2485540A1 (en) 1981-12-31
ZA814394B (en) 1982-09-29
AU7241081A (en) 1982-01-07
FR2485540B1 (en) 1984-02-24
JPS5738785A (en) 1982-03-03

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