FR2463777A1 - Nouveaux derives du 5a-pregnan-20-ol, leur procede de preparation et leur application comme medicaments - Google Patents

Nouveaux derives du 5a-pregnan-20-ol, leur procede de preparation et leur application comme medicaments Download PDF

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Publication number
FR2463777A1
FR2463777A1 FR7920840A FR7920840A FR2463777A1 FR 2463777 A1 FR2463777 A1 FR 2463777A1 FR 7920840 A FR7920840 A FR 7920840A FR 7920840 A FR7920840 A FR 7920840A FR 2463777 A1 FR2463777 A1 FR 2463777A1
Authority
FR
France
Prior art keywords
pregnan
amino
formula
carbodiimide
radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7920840A
Other languages
English (en)
French (fr)
Other versions
FR2463777B1 (it
Inventor
Roger Deraedt
Vesperto Torelli
Jean Vacher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7920840A priority Critical patent/FR2463777A1/fr
Priority to SE8005309A priority patent/SE446006B/sv
Priority to ZA00804473A priority patent/ZA804473B/xx
Priority to FI802462A priority patent/FI68844C/fi
Priority to GB8026312A priority patent/GB2057448B/en
Priority to ES494256A priority patent/ES8103760A1/es
Priority to IT49507/80A priority patent/IT1145382B/it
Priority to PT71700A priority patent/PT71700B/pt
Priority to NL8004600A priority patent/NL8004600A/nl
Priority to BE0/201765A priority patent/BE884794A/fr
Priority to JP11189680A priority patent/JPS5659800A/ja
Priority to CA000358412A priority patent/CA1140111A/fr
Priority to IE1737/80A priority patent/IE50226B1/en
Priority to DK352380A priority patent/DK352380A/da
Priority to CH616280A priority patent/CH646182A5/fr
Priority to HU80802040A priority patent/HU180376B/hu
Priority to AU61486/80A priority patent/AU529528B2/en
Priority to AT0420880A priority patent/AT373902B/de
Priority to DE19803031161 priority patent/DE3031161A1/de
Publication of FR2463777A1 publication Critical patent/FR2463777A1/fr
Priority to US06/292,791 priority patent/US4424218A/en
Application granted granted Critical
Publication of FR2463777B1 publication Critical patent/FR2463777B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
FR7920840A 1979-08-17 1979-08-17 Nouveaux derives du 5a-pregnan-20-ol, leur procede de preparation et leur application comme medicaments Granted FR2463777A1 (fr)

Priority Applications (20)

Application Number Priority Date Filing Date Title
FR7920840A FR2463777A1 (fr) 1979-08-17 1979-08-17 Nouveaux derives du 5a-pregnan-20-ol, leur procede de preparation et leur application comme medicaments
SE8005309A SE446006B (sv) 1979-08-17 1980-07-22 (20s) 3alfa-/(aminoacetyl)-amino/-5alfa-preganan-20-ol och additionssalter derav samt farmaceutiska kompositioner innehallande dessa
ZA00804473A ZA804473B (en) 1979-08-17 1980-07-24 Derivatives of 5a-pregnan-20-01 and its salts with acids, their preparation, their use as medicaments and the compositions containing them
FI802462A FI68844C (fi) 1979-08-17 1980-08-06 Foerfarande foer framstaellning av (20s) 3alfa-((aminoacetyl)amino)-5alfa-pregnan-20-ol och dess salter
GB8026312A GB2057448B (en) 1979-08-17 1980-08-13 (20s)-3-(aminoacetylamino)-5-pregnan-20-ol and its acid addition salts
IT49507/80A IT1145382B (it) 1979-08-17 1980-08-14 Derivato di salfa-pregnan-20-olo e relativi sali di addizione acida procedimento per la loro preparazione loro applicazione come farmaci e composizione che li includono
PT71700A PT71700B (fr) 1979-08-17 1980-08-14 Procede de preparation d'un nouveau derive du (20s)3alpha-<(amino acetyl)amino>5alpha-pregnan-20-ol et de ses sels
NL8004600A NL8004600A (nl) 1979-08-17 1980-08-14 Nieuw derivaat van 5alfa-pregnanol-20 en zijn zouten met zuren, bereiding en toepassing als geneesmiddelen van deze stoffen en preparaten, die ze bevatten.
BE0/201765A BE884794A (fr) 1979-08-17 1980-08-14 Nouveau derive du 5 alpha-pregnan-20-ol et ses sels avec les acides, leur preparation, leur application comme medicaments et les compositions les renfermant
ES494256A ES8103760A1 (es) 1979-08-17 1980-08-14 Procedimiento de preparacion de (20 s) - 3 - - ((aminoace- til)amino)-5 - - pregnan- 20 - ol
JP11189680A JPS5659800A (en) 1979-08-17 1980-08-15 Novel derivative of 5 alphaapregnanee200oll200ol and salt of said acid* these manufacture* use as drug and composition containing them
IE1737/80A IE50226B1 (en) 1979-08-17 1980-08-15 Derivative of 5alpha-pregnan-20-ol and its acid addition salts
DK352380A DK352380A (da) 1979-08-17 1980-08-15 Fremgangsmaade til fremstilling af (20s)-3alfa-( (aminoacetyl)-amino)-5alfa-pregnan-20-ol eller additionssalte deraf
CH616280A CH646182A5 (fr) 1979-08-17 1980-08-15 Derive du 5-pregnan-20-ol et ses sels avec les acides, leur preparation et medicaments les renfermant.
HU80802040A HU180376B (en) 1979-08-17 1980-08-15 Process for preparing /20s/-3alpha-//aminoacetyl/-amino/-5alpha-pregnan-20-ol and salts thereof
AU61486/80A AU529528B2 (en) 1979-08-17 1980-08-15 5 alpha-pre gnan-20-ols
CA000358412A CA1140111A (fr) 1979-08-17 1980-08-15 PROCEDE DE PREPARATION D'UN NOUVEAU DERIVE DU (20S) 3.alpha.- /(AMINO-ACETYL)AMINO/ 5.alpha.-PREGNAN-20-OL ET DE SES SELS
AT0420880A AT373902B (de) 1979-08-17 1980-08-18 Verfahren zur herstellung des neuen (20s)-3 alpha-((aminoacetyl)amino)-5 alpha-pregnan-20-ols und seiner salze
DE19803031161 DE3031161A1 (de) 1979-08-17 1980-08-18 Neues 5 (alpha)-pregnan-20-ol-derivat und dessen salze mit saeuren, deren herstellung, deren verwendung als arzneimittel und die diese enthaltenden zusammensetzungen
US06/292,791 US4424218A (en) 1979-08-17 1981-08-14 Novel 3 α-amino steroids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7920840A FR2463777A1 (fr) 1979-08-17 1979-08-17 Nouveaux derives du 5a-pregnan-20-ol, leur procede de preparation et leur application comme medicaments

Publications (2)

Publication Number Publication Date
FR2463777A1 true FR2463777A1 (fr) 1981-02-27
FR2463777B1 FR2463777B1 (it) 1983-04-29

Family

ID=9228902

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7920840A Granted FR2463777A1 (fr) 1979-08-17 1979-08-17 Nouveaux derives du 5a-pregnan-20-ol, leur procede de preparation et leur application comme medicaments

Country Status (19)

Country Link
JP (1) JPS5659800A (it)
AT (1) AT373902B (it)
AU (1) AU529528B2 (it)
BE (1) BE884794A (it)
CA (1) CA1140111A (it)
CH (1) CH646182A5 (it)
DE (1) DE3031161A1 (it)
DK (1) DK352380A (it)
ES (1) ES8103760A1 (it)
FI (1) FI68844C (it)
FR (1) FR2463777A1 (it)
GB (1) GB2057448B (it)
HU (1) HU180376B (it)
IE (1) IE50226B1 (it)
IT (1) IT1145382B (it)
NL (1) NL8004600A (it)
PT (1) PT71700B (it)
SE (1) SE446006B (it)
ZA (1) ZA804473B (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2494698A1 (fr) * 1980-11-21 1982-05-28 Roussel Uclaf Nouveaux derives steroides 3-amino substitues, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
FR2515188A1 (fr) * 1981-10-27 1983-04-29 Roussel Uclaf Nouveaux derives du 3-amino-pregn-5-ene, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3196169A (en) * 1964-11-03 1965-07-20 American Home Prod Aminoacyl aminosteroids

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3196169A (en) * 1964-11-03 1965-07-20 American Home Prod Aminoacyl aminosteroids

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
EXBK/65 *
EXBK/67 *

Also Published As

Publication number Publication date
PT71700A (fr) 1980-09-01
HU180376B (en) 1983-02-28
AT373902B (de) 1984-03-12
ES494256A0 (es) 1981-03-16
CA1140111A (fr) 1983-01-25
IT1145382B (it) 1986-11-05
ATA420880A (de) 1983-07-15
FI68844B (fi) 1985-07-31
ES8103760A1 (es) 1981-03-16
FI802462A (fi) 1981-02-18
PT71700B (fr) 1982-01-22
IE801737L (en) 1981-02-17
FI68844C (fi) 1985-11-11
AU529528B2 (en) 1983-06-09
DE3031161A1 (de) 1981-03-26
IT8049507A0 (it) 1980-08-14
JPS5659800A (en) 1981-05-23
DK352380A (da) 1981-02-18
CH646182A5 (fr) 1984-11-15
SE446006B (sv) 1986-08-04
ZA804473B (en) 1981-07-29
GB2057448A (en) 1981-04-01
SE8005309L (sv) 1981-02-18
GB2057448B (en) 1983-05-18
NL8004600A (nl) 1981-02-19
FR2463777B1 (it) 1983-04-29
DE3031161C2 (it) 1988-09-29
AU6148680A (en) 1981-02-19
BE884794A (fr) 1981-02-16
IE50226B1 (en) 1986-03-05

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