FR2460919B1 - - Google Patents

Info

Publication number
FR2460919B1
FR2460919B1 FR7917986A FR7917986A FR2460919B1 FR 2460919 B1 FR2460919 B1 FR 2460919B1 FR 7917986 A FR7917986 A FR 7917986A FR 7917986 A FR7917986 A FR 7917986A FR 2460919 B1 FR2460919 B1 FR 2460919B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7917986A
Other versions
FR2460919A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PROD SYNTHESE STE INDLE
Original Assignee
PROD SYNTHESE STE INDLE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PROD SYNTHESE STE INDLE filed Critical PROD SYNTHESE STE INDLE
Priority to FR7917986A priority Critical patent/FR2460919A1/fr
Priority to NLAANVRAGE8003601,A priority patent/NL190237C/xx
Priority to CH502680A priority patent/CH644348A5/fr
Priority to US06/164,931 priority patent/US4301163A/en
Priority to ES493092A priority patent/ES493092A0/es
Priority to BE0/201322A priority patent/BE884212A/fr
Priority to GB8022612A priority patent/GB2054588B/en
Priority to DE19803026201 priority patent/DE3026201A1/de
Priority to IT12595/80A priority patent/IT1136190B/it
Priority to JP9408580A priority patent/JPS5615250A/ja
Priority to CA000356003A priority patent/CA1148547A/fr
Publication of FR2460919A1 publication Critical patent/FR2460919A1/fr
Application granted granted Critical
Publication of FR2460919B1 publication Critical patent/FR2460919B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
FR7917986A 1979-07-11 1979-07-11 Amino-ethers oxydes, leur procede de preparation et leur application en therapeutique Granted FR2460919A1 (fr)

Priority Applications (11)

Application Number Priority Date Filing Date Title
FR7917986A FR2460919A1 (fr) 1979-07-11 1979-07-11 Amino-ethers oxydes, leur procede de preparation et leur application en therapeutique
NLAANVRAGE8003601,A NL190237C (nl) 1979-07-11 1980-06-21 Amino-ethers en geneesmiddel dat deze amino-ethers bevat.
CH502680A CH644348A5 (fr) 1979-07-11 1980-06-30 Amino-ethers oxydes, leur procede de preparation et medicament les contenant.
US06/164,931 US4301163A (en) 1979-07-11 1980-07-01 Amino-ether oxides and use thereof in therapy
ES493092A ES493092A0 (es) 1979-07-11 1980-07-04 Procedimiento de preparacion de amino-eteres oxidos
BE0/201322A BE884212A (fr) 1979-07-11 1980-07-08 Amino-etehrs oxydes, leur procede de preparation et leur application en therapeutique.
GB8022612A GB2054588B (en) 1979-07-11 1980-07-10 Amino-ether oxides and pharmaceutical formulations thereof
DE19803026201 DE3026201A1 (de) 1979-07-11 1980-07-10 Aminoaetheroxide, verfahren zu ihrer herstellung sowie ihre therapeutische verwendung
IT12595/80A IT1136190B (it) 1979-07-11 1980-07-11 Ossidi di ammino eteri utilizzabili particolarmente come anestetici analgesici e spasmolitici e loro metodo di fabbricazione
JP9408580A JPS5615250A (en) 1979-07-11 1980-07-11 Aminoether type oxide* its manufacture and therapeutic use
CA000356003A CA1148547A (fr) 1979-07-11 1980-07-11 Amino-ethers

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7917986A FR2460919A1 (fr) 1979-07-11 1979-07-11 Amino-ethers oxydes, leur procede de preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
FR2460919A1 FR2460919A1 (fr) 1981-01-30
FR2460919B1 true FR2460919B1 (fr) 1983-11-10

Family

ID=9227765

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7917986A Granted FR2460919A1 (fr) 1979-07-11 1979-07-11 Amino-ethers oxydes, leur procede de preparation et leur application en therapeutique

Country Status (11)

Country Link
US (1) US4301163A (fr)
JP (1) JPS5615250A (fr)
BE (1) BE884212A (fr)
CA (1) CA1148547A (fr)
CH (1) CH644348A5 (fr)
DE (1) DE3026201A1 (fr)
ES (1) ES493092A0 (fr)
FR (1) FR2460919A1 (fr)
GB (1) GB2054588B (fr)
IT (1) IT1136190B (fr)
NL (1) NL190237C (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE28069T1 (de) * 1982-09-07 1987-07-15 Ciba Geigy Ag Propylamin-derivate, verfahren zu ihrer herstellung, pharmazeutische praeparate enthaltend diese verbindungen, sowie ihre therapeutische verwendung.
US4824868A (en) * 1982-09-07 1989-04-25 Ciba-Geigy Corporation Propylamine derivatives useful for the treatment of dementia
US4692469A (en) * 1982-09-07 1987-09-08 Ciba-Geigy Corporation Propylamine derivatives
ZW6584A1 (en) * 1983-04-18 1985-04-17 Glaxo Group Ltd Phenethanolamine derivatives
FR2643369B1 (fr) * 1989-02-20 1991-07-05 Jouveinal Sa La (+) 1-((3,4,5-trimethoxy) benzyloxymethyl)-1-phenyl-n,n-dimethyl-n-propylamine, son procede de preparation et son application en therapeutique
US5266599A (en) * 1989-02-20 1993-11-30 Jouveinal S.A. Use of (+)-1-[(3,4,5-trimethoxy)-benzyloxymethyl]-1-phenyl-N,N-dimethyl-n-propylamine to increase gastric discharge in a subject
US5245080A (en) * 1989-02-20 1993-09-14 Jouveinal Sa (+)-1-[(3,4,5-trimethoxy)-benzyloxymethyl]-1-phenyl-N,N-dimethyl-N-propylamine, process for preparing it and its therapeutical use
DE69208088T2 (de) * 1991-07-05 1996-11-14 Merck Sharp & Dohme Aromatische verbindungen, diese enthaltende pharmazeutische zusammensetzungen und ihre therapeutische anwendung
US5472978A (en) * 1991-07-05 1995-12-05 Merck Sharp & Dohme Ltd. Aromatic compounds, pharmaceutical compositions containing them and their use in therapy
US5495047A (en) * 1991-07-10 1996-02-27 Merck, Sharp & Dohme (Ltd.) Fused tricyclic compounds, pharmaceutical compositions containing them and their use in therapy
JPH06509090A (ja) * 1991-07-10 1994-10-13 メルク　シヤープ　エンド　ドーム　リミテツド 芳香族化合物、それらを含む組成物、及び治療におけるそれらの使用
US5328927A (en) * 1992-03-03 1994-07-12 Merck Sharpe & Dohme, Ltd. Hetercyclic compounds, processes for their preparation and pharmaceutical compositions containing them
GB9211193D0 (en) * 1992-05-27 1992-07-08 Merck Sharp & Dohme Therapeutic agents
AU4718093A (en) * 1992-07-31 1994-03-03 Merck Sharp & Dohme Limited Substituted amines as tachykinin receptor antagonists
US5948820A (en) 1994-08-22 1999-09-07 Yoshitomi Pharmaceutical Industries, Ltd. Benzene compound and pharmaceutical use thereof
DE69524962T4 (de) * 1994-08-22 2003-08-28 Mitsubishi Pharma Corp., Osaka Benzolderivate und deren medizinische verwendung
PT1471054E (pt) 2002-01-11 2009-09-23 Daiichi Sankyo Co Ltd Derivado de aminoálcool ou derivado de ácido fosfónico e composição medicinal que os contém
CA2491797A1 (fr) * 2002-07-10 2004-01-22 Warner-Lambert Company Llc Compositions gastrointestinales
US20040010035A1 (en) * 2002-07-15 2004-01-15 Ciociola Arthur A. Gastrointestinal compositions
US6986901B2 (en) * 2002-07-15 2006-01-17 Warner-Lambert Company Llc Gastrointestinal compositions
AU2003247042A1 (en) * 2002-07-10 2004-02-02 Warner-Lambert Company Llc Gastrointestinal compositions comprising gaba derivatives
KR20110136901A (ko) 2004-02-24 2011-12-21 상꾜 가부시키가이샤 아미노 알코올 화합물
SE0400968D0 (sv) * 2004-04-14 2004-04-14 Astrazeneca Ab Aryl glycine ether derivatives and their use
US7879913B2 (en) * 2005-06-28 2011-02-01 Catholic Healthcare West Iptakalim hydrochloride for decreasing nicotine use
RU2008152751A (ru) * 2006-06-06 2010-07-20 Антиб Терапьютикс Инк. (Ca) Соли тримебутина и n-десметилтримебутина

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2649445A (en) * 1948-02-28 1953-08-18 Bristol Lab Chloracetic acid ester of diphenyl ethanols
ES251290A1 (es) * 1958-08-21 1960-04-01 Parke Davis & Co Un procedimiento para la producciën de alcohilaminas arilsustituidas
GB1119835A (en) * 1964-07-20 1968-07-17 Analyses Et De Rech S Biolog M Process for the preparation of basic ethers
US4194009A (en) * 1974-01-10 1980-03-18 Eli Lilly And Company Aryloxyphenylpropylamines for obtaining a psychotropic effect
US4207343A (en) * 1978-06-22 1980-06-10 Eli Lilly And Company 1-Phenyl-3-(substituted phenoxy)propylamines

Also Published As

Publication number Publication date
ES8103020A1 (es) 1981-02-16
GB2054588B (en) 1983-06-29
IT1136190B (it) 1986-08-27
GB2054588A (en) 1981-02-18
JPS6253504B2 (fr) 1987-11-10
CA1148547A (fr) 1983-06-21
CH644348A5 (fr) 1984-07-31
US4301163A (en) 1981-11-17
DE3026201C2 (fr) 1990-11-08
NL190237C (nl) 1993-12-16
IT8012595A0 (it) 1980-07-11
DE3026201A1 (de) 1981-02-26
ES493092A0 (es) 1981-02-16
NL8003601A (nl) 1981-01-13
JPS5615250A (en) 1981-02-14
FR2460919A1 (fr) 1981-01-30
NL190237B (nl) 1993-07-16
BE884212A (fr) 1981-01-08
US4301163B1 (fr) 1990-01-23

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Legal Events

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