FR2455017A1 - Procede de preparation du chloro-3 methyl-2 propanol optiquement actif - Google Patents
Procede de preparation du chloro-3 methyl-2 propanol optiquement actifInfo
- Publication number
- FR2455017A1 FR2455017A1 FR7910589A FR7910589A FR2455017A1 FR 2455017 A1 FR2455017 A1 FR 2455017A1 FR 7910589 A FR7910589 A FR 7910589A FR 7910589 A FR7910589 A FR 7910589A FR 2455017 A1 FR2455017 A1 FR 2455017A1
- Authority
- FR
- France
- Prior art keywords
- chloro
- methyl propanol
- pancreatic lipase
- ester
- optically active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000019280 Pancreatic lipases Human genes 0.000 title abstract 2
- 108050006759 Pancreatic lipases Proteins 0.000 title abstract 2
- 229940116369 pancreatic lipase Drugs 0.000 title abstract 2
- 125000001309 chloro group Chemical group Cl* 0.000 title 1
- 150000002148 esters Chemical class 0.000 title 1
- 230000007062 hydrolysis Effects 0.000 title 1
- 238000006460 hydrolysis reaction Methods 0.000 title 1
- -1 methyl propanol Chemical compound 0.000 title 1
- 230000000707 stereoselective effect Effects 0.000 title 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 2
- UDZGHTHYVWDFFY-UHFFFAOYSA-N 2-chlorobutan-2-ol Chemical compound CCC(C)(O)Cl UDZGHTHYVWDFFY-UHFFFAOYSA-N 0.000 abstract 1
- NQULNQFAEYXUJJ-UHFFFAOYSA-N 3-chloro-2-methylpropan-1-ol Chemical class OCC(C)CCl NQULNQFAEYXUJJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000011149 active material Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- VRQVVMDWGGWHTJ-CQSZACIVSA-N methotrimeprazine Chemical compound C1=CC=C2N(C[C@H](C)CN(C)C)C3=CC(OC)=CC=C3SC2=C1 VRQVVMDWGGWHTJ-CQSZACIVSA-N 0.000 abstract 1
- 229940042053 methotrimeprazine Drugs 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000011148 porous material Substances 0.000 abstract 1
- 239000000377 silicon dioxide Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7910589A FR2455017A1 (fr) | 1979-04-26 | 1979-04-26 | Procede de preparation du chloro-3 methyl-2 propanol optiquement actif |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7910589A FR2455017A1 (fr) | 1979-04-26 | 1979-04-26 | Procede de preparation du chloro-3 methyl-2 propanol optiquement actif |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2455017A1 true FR2455017A1 (fr) | 1980-11-21 |
| FR2455017B1 FR2455017B1 (enExample) | 1982-08-20 |
Family
ID=9224773
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7910589A Granted FR2455017A1 (fr) | 1979-04-26 | 1979-04-26 | Procede de preparation du chloro-3 methyl-2 propanol optiquement actif |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2455017A1 (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4518813A (en) * | 1981-10-02 | 1985-05-21 | Basf Aktiengesellschaft | Optically active units for the synthesis of the side chain of (R,R,R)-α-tocopherol and their preparation |
| US4923810A (en) * | 1988-08-24 | 1990-05-08 | Genzyme Corporation | Resolution of glycidyl esters to high enantiomeric excess |
| EP0549872A3 (en) * | 1991-11-15 | 1994-08-17 | Lonza Ag | Process for the preparation of (2r,e3)-4-halo-3-buten-2-ols |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2181297A (en) * | 1937-02-01 | 1939-11-28 | Dow Chemical Co | Hydrolysis of 1,3-dihalo-isobutanes |
-
1979
- 1979-04-26 FR FR7910589A patent/FR2455017A1/fr active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2181297A (en) * | 1937-02-01 | 1939-11-28 | Dow Chemical Co | Hydrolysis of 1,3-dihalo-isobutanes |
Non-Patent Citations (4)
| Title |
|---|
| CA1953 * |
| CA1966 * |
| CA1967 * |
| CA1975 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4518813A (en) * | 1981-10-02 | 1985-05-21 | Basf Aktiengesellschaft | Optically active units for the synthesis of the side chain of (R,R,R)-α-tocopherol and their preparation |
| US4923810A (en) * | 1988-08-24 | 1990-05-08 | Genzyme Corporation | Resolution of glycidyl esters to high enantiomeric excess |
| EP0549872A3 (en) * | 1991-11-15 | 1994-08-17 | Lonza Ag | Process for the preparation of (2r,e3)-4-halo-3-buten-2-ols |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2455017B1 (enExample) | 1982-08-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |