FR2451582A1 - Procede radio-immunologique perfectionne pour la separation d'un ligand libre du ligand fixe a un anticorps - Google Patents

Procede radio-immunologique perfectionne pour la separation d'un ligand libre du ligand fixe a un anticorps

Info

Publication number
FR2451582A1
FR2451582A1 FR8005450A FR8005450A FR2451582A1 FR 2451582 A1 FR2451582 A1 FR 2451582A1 FR 8005450 A FR8005450 A FR 8005450A FR 8005450 A FR8005450 A FR 8005450A FR 2451582 A1 FR2451582 A1 FR 2451582A1
Authority
FR
France
Prior art keywords
ligand
separation
fixed
antibody
free
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8005450A
Other languages
English (en)
Other versions
FR2451582B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Technion Research and Development Foundation Ltd
Original Assignee
Technion Research and Development Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technion Research and Development Foundation Ltd filed Critical Technion Research and Development Foundation Ltd
Publication of FR2451582A1 publication Critical patent/FR2451582A1/fr
Application granted granted Critical
Publication of FR2451582B1 publication Critical patent/FR2451582B1/fr
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/5375—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by changing the physical or chemical properties of the medium or immunochemicals, e.g. temperature, density, pH, partitioning
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/816—Alkaloids, amphetamines, and barbiturates
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/817—Steroids or hormones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/824—Immunological separation techniques

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'INVENTION CONCERNE UN PERFECTIONNEMENT A LA METHODE DE DETERMINATION SPECIFIQUE DE FIXATION POUR DETERMINER UN LIGAND DANS UN MILIEU. LE PROCEDE DE L'INVENTION EST CARACTERISE EN CE QUE L'ON EFFECTUE LA SEPARATION DE LADITE FRACTION FIXEE D'AVEC LADITE FRACTION LIBRE PAR UNE TECHNIQUE D'EXTRACTION PAR SOLVANT UTILISANT UN SOLVANT ORGANIQUE, LEDIT SOLVANT ORGANIQUE ETANT LEGEREMENT MISCIBLE AVEC L'EAU OU TOTALEMENT NON MISCIBLE AVEC L'EAU, AYANT LA PROPRIETE D'UN POUVOIR D'EXTRACTION SELECTIVE MARQUE VIS-A-VIS DE L'ANTIGENE ET POSSEDANT LA CARACTERISTIQUE DE GELER L'EQUILIBRE ENTRE LA FRACTION LIBRE ET LA FRACTION FIXEE.
FR8005450A 1979-03-11 1980-03-11 Procede radio-immunologique perfectionne pour la separation d'un ligand libre du ligand fixe a un anticorps Granted FR2451582A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL56839A IL56839A0 (en) 1979-03-11 1979-03-11 Improvement in specific binding assay technique

Publications (2)

Publication Number Publication Date
FR2451582A1 true FR2451582A1 (fr) 1980-10-10
FR2451582B1 FR2451582B1 (fr) 1984-03-02

Family

ID=11050917

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8005450A Granted FR2451582A1 (fr) 1979-03-11 1980-03-11 Procede radio-immunologique perfectionne pour la separation d'un ligand libre du ligand fixe a un anticorps

Country Status (9)

Country Link
US (1) US4645747A (fr)
JP (1) JPS55160855A (fr)
CA (1) CA1140463A (fr)
DE (1) DE3009154A1 (fr)
FR (1) FR2451582A1 (fr)
GB (1) GB2103790B (fr)
IL (1) IL56839A0 (fr)
NL (1) NL8004290A (fr)
SE (1) SE442785B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL60645A (en) * 1980-07-21 1984-02-29 Cais Michael Method and device for mass transfer and separation through selective barriers
FI841023A0 (fi) * 1984-03-14 1984-03-14 Labsystems Oy Foerfarande foer utfoering av immunobestaemningar
US5073341A (en) * 1985-08-21 1991-12-17 Biotope, Inc. Devices for conducting specific binding assays
WO1987001206A1 (fr) * 1985-08-21 1987-02-26 William Rudolph Hargreaves Procedes et dispositifs pour separer, melanger, et detecter des constituants dans des analyses specifiques de liaison
US5501949A (en) * 1985-12-10 1996-03-26 Murex Diagnostics Corporation Particle bound binding component immunoassay
SE8703733L (sv) * 1987-09-28 1989-03-29 Ragnar Soedergaard Analysmetod foer bestaemning av procent fri substans i biologiska vaetskor genom jaemviktsfoerdelning i olja/vatten system
EP0344276B1 (fr) * 1987-12-01 1993-06-23 Boehringer Mannheim Corporation Procedes et dispositifs servant a effectuer des analyses
US5252492A (en) * 1991-03-12 1993-10-12 University Of Utah Research Foundation Fluorescence assay for ligand or receptor utilizing size exclusion
DE4111527C2 (de) * 1991-04-09 1994-07-07 Peter Dr Miethe Affinitätschromatographisches Verfahren mit mobiler organischer Phase
GB2312746B (en) 1996-04-24 2000-07-19 Molecular Light Technology Lim Detection of an analyte in a Water Immiscible Solvent
US5856194A (en) 1996-09-19 1999-01-05 Abbott Laboratories Method for determination of item of interest in a sample
US8993243B2 (en) * 2011-01-10 2015-03-31 Wisconsin Alumni Research Foundation Method for isolating weakly interacting molecules from a fluidic sample

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2262548A1 (fr) * 1974-03-02 1975-09-26 Merck Patent Gmbh
US3929981A (en) * 1974-02-27 1975-12-30 Squibb & Sons Inc Method for determining thyroid function
FR2371687A1 (fr) * 1976-11-19 1978-06-16 Ames Yissum Ltd Procede et necessaire pour essai de dosage avec fixation specifique en utilisant de l'alcool polyvinylique comme agent de separation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1566098A (en) * 1975-11-14 1980-04-30 Nat Res Dev Separation of solid and liquid components of mixtures
US4220450A (en) * 1978-04-05 1980-09-02 Syva Company Chemically induced fluorescence immunoassay
SE7812237L (sv) * 1978-11-28 1980-05-29 Pharmacia Diagnostics Ab Koncentrationsbestemning av substanser med formaga att biospecifikt binda molekyler med biologiskt ursprung
US4301139A (en) * 1979-06-21 1981-11-17 Ames-Yissum Ltd. Multilayer column chromatography specific binding assay method, test device and test kit
IL58943A (en) * 1979-12-12 1983-05-15 Cais Michael Method and device for mass transfer operations in immunoassays and other applications
IL63363A (en) * 1981-07-20 1986-08-31 Cais Michael Non-centrifugation method for immunoassay of materials

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929981A (en) * 1974-02-27 1975-12-30 Squibb & Sons Inc Method for determining thyroid function
FR2262548A1 (fr) * 1974-03-02 1975-09-26 Merck Patent Gmbh
FR2371687A1 (fr) * 1976-11-19 1978-06-16 Ames Yissum Ltd Procede et necessaire pour essai de dosage avec fixation specifique en utilisant de l'alcool polyvinylique comme agent de separation

Also Published As

Publication number Publication date
GB2103790B (en) 1984-12-12
NL8004290A (nl) 1982-02-16
SE442785B (sv) 1986-01-27
FR2451582B1 (fr) 1984-03-02
JPS55160855A (en) 1980-12-15
DE3009154A1 (de) 1980-09-25
US4645747A (en) 1987-02-24
CA1140463A (fr) 1983-02-01
GB2103790A (en) 1983-02-23
SE8005658L (sv) 1982-02-12
IL56839A0 (en) 1979-05-31

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