FR2451379A1 - Procede de production d'a-(alkyle inferieur)-furocoumarines et nouveaux composes intermediaires obtenus - Google Patents
Procede de production d'a-(alkyle inferieur)-furocoumarines et nouveaux composes intermediaires obtenusInfo
- Publication number
- FR2451379A1 FR2451379A1 FR8005711A FR8005711A FR2451379A1 FR 2451379 A1 FR2451379 A1 FR 2451379A1 FR 8005711 A FR8005711 A FR 8005711A FR 8005711 A FR8005711 A FR 8005711A FR 2451379 A1 FR2451379 A1 FR 2451379A1
- Authority
- FR
- France
- Prior art keywords
- lower alkyl
- furocoumarins
- paremplee
- producing
- compounds obtained
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
Abstract
L'INVENTION CONCERNE UN PROCEDE DE PRODUCTION D'A-(ALKYLE INFERIEUR)-FUROCOUMARINES. DES A-(ALKYLE INFERIEUR)-FUROCOUMARINES SONT PRODUITES PAR FORMATION D'UN ETHER DE B-HALOGENALC-2-ENYLE, PAR EXEMPLE DE B-HALOGENALLYLE D'UNE HYDROXYCOUMARINE PORTANT UN ATOME ACTIF D'HYDROGENE EN POSITION ORTHO PAR RAPPORT AU GROUPE HYDROXY, ET PAR CHAUFFAGE DE L'ETHER FORME, DE PREFERENCE DANS DE LA DIMETHYLANILINE OU DANS UN SOLVANT AMINE BASIQUE SIMILAIRE. UNE TRANSPOSITION ANORMALE DE CLAISEN PRODUIT UNE NOUVELLE O-HYDROXY-(B-HALOGENALC-2-ENYL)-COUMARINE INTERMEDIAIRE QUI PEUT ETRE DESHYDROGENEE DIRECTEMENT, SANS ISOLEMENT, EN L'A-(ALKYLE INFERIEUR)-FUROCOUMARINE DESIREE, PAR EXEMPLE L'A-METHYLFUROCOUMARINE. APPLICATION A LA PREPARATION, NOTAMMENT, DU TRIMETHYLPSORALENE TRES UTILISE DANS LE TRAITEMENT DU VITILIGO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/020,935 US4216154A (en) | 1979-03-15 | 1979-03-15 | Process for making α-loweralkylfurocoumarins |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2451379A1 true FR2451379A1 (fr) | 1980-10-10 |
FR2451379B1 FR2451379B1 (fr) | 1983-07-08 |
Family
ID=21801374
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR8005711A Granted FR2451379A1 (fr) | 1979-03-15 | 1980-03-14 | Procede de production d'a-(alkyle inferieur)-furocoumarines et nouveaux composes intermediaires obtenus |
Country Status (11)
Country | Link |
---|---|
US (1) | US4216154A (fr) |
AT (1) | AT371467B (fr) |
AU (1) | AU532881B2 (fr) |
BE (1) | BE882236A (fr) |
CA (1) | CA1146952A (fr) |
DE (1) | DE3009508A1 (fr) |
FR (1) | FR2451379A1 (fr) |
GB (1) | GB2047686B (fr) |
IT (1) | IT1193523B (fr) |
NL (1) | NL8001517A (fr) |
SE (3) | SE452886B (fr) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1165797B (it) * | 1982-10-18 | 1987-04-29 | Consiglio Nazionale Ricerche | Procedimento di preparazione di alchilangelicine esenti da psoraleni ed alchilangolicine ottenute col procedimento |
AU649992B2 (en) * | 1989-10-26 | 1994-06-09 | George D. Cimino | Activation compounds and methods for nucleic acid sterilization |
US5399719A (en) * | 1993-06-28 | 1995-03-21 | Steritech, Inc. | Compounds for the photodecontamination of pathogens in blood |
US5871900A (en) * | 1993-06-28 | 1999-02-16 | Cerus Corporation | Method of inactivating pathogens in biological fluids using photoactivated 5-primaryamino psoralens |
US5556993A (en) | 1993-06-28 | 1996-09-17 | Steritech, Inc. | Compounds for the photodecontamination of pathogens in blood |
US6420570B1 (en) | 1993-06-28 | 2002-07-16 | Cerus Corporation | Psoralen compounds |
US5593823A (en) * | 1993-06-28 | 1997-01-14 | Cerus Corporation | Method for inactivating pathogens in blood using photoactivation of 4'-primary amino-substituted psoralens |
US6004742A (en) * | 1993-06-28 | 1999-12-21 | Cerus Corporation | Method for inactivation of pathogens in platelets using 4' and 5' primary amino-substituted psoralens |
US6004741A (en) * | 1993-06-28 | 1999-12-21 | Cerus Corporation | Method for the photoactivation of 4' and 5' primary aminoalkyl psoralens in platelet preparations |
US20020115585A1 (en) * | 1996-06-07 | 2002-08-22 | Hei Derek J. | Method and devices for the removal of psoralens from blood products |
AU747842B2 (en) | 1997-11-20 | 2002-05-23 | Cerus Corporation | New psoralens for pathogen inactivation |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3201421A (en) * | 1962-05-09 | 1965-08-17 | Dept Of Chemistry | Preparation of alkyl psoralens |
-
1979
- 1979-03-15 US US06/020,935 patent/US4216154A/en not_active Expired - Lifetime
-
1980
- 1980-02-29 CA CA000346784A patent/CA1146952A/fr not_active Expired
- 1980-03-10 GB GB8008006A patent/GB2047686B/en not_active Expired
- 1980-03-12 DE DE19803009508 patent/DE3009508A1/de not_active Withdrawn
- 1980-03-12 IT IT20519/80A patent/IT1193523B/it active
- 1980-03-14 NL NL8001517A patent/NL8001517A/nl not_active Application Discontinuation
- 1980-03-14 AU AU56475/80A patent/AU532881B2/en not_active Ceased
- 1980-03-14 FR FR8005711A patent/FR2451379A1/fr active Granted
- 1980-03-14 AT AT0141880A patent/AT371467B/de not_active IP Right Cessation
- 1980-03-14 BE BE0/199805A patent/BE882236A/fr not_active IP Right Cessation
- 1980-03-14 SE SE8002034A patent/SE452886B/sv not_active IP Right Cessation
-
1985
- 1985-02-25 SE SE8500913A patent/SE453087B/sv not_active IP Right Cessation
-
1987
- 1987-03-10 SE SE8700999A patent/SE453393B/sv not_active IP Right Cessation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3201421A (en) * | 1962-05-09 | 1965-08-17 | Dept Of Chemistry | Preparation of alkyl psoralens |
Non-Patent Citations (1)
Title |
---|
EXBK/74 * |
Also Published As
Publication number | Publication date |
---|---|
IT8020519A0 (it) | 1980-03-12 |
CA1146952A (fr) | 1983-05-24 |
SE8700999D0 (sv) | 1987-03-10 |
ATA141880A (de) | 1982-11-15 |
AU5647580A (en) | 1980-09-18 |
SE453393B (sv) | 1988-02-01 |
SE8500913D0 (sv) | 1985-02-25 |
NL8001517A (nl) | 1980-09-17 |
SE452886B (sv) | 1987-12-21 |
FR2451379B1 (fr) | 1983-07-08 |
GB2047686B (en) | 1983-09-07 |
GB2047686A (en) | 1980-12-03 |
SE453087B (sv) | 1988-01-11 |
SE8002034L (sv) | 1980-09-16 |
SE8700999L (sv) | 1987-03-10 |
IT1193523B (it) | 1988-07-08 |
US4216154A (en) | 1980-08-05 |
DE3009508A1 (de) | 1980-09-25 |
BE882236A (fr) | 1980-07-01 |
AT371467B (de) | 1983-06-27 |
AU532881B2 (en) | 1983-10-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
CD | Change of name or company name | ||
ST | Notification of lapse |