FR2449085B1 - - Google Patents

Info

Publication number
FR2449085B1
FR2449085B1 FR8005710A FR8005710A FR2449085B1 FR 2449085 B1 FR2449085 B1 FR 2449085B1 FR 8005710 A FR8005710 A FR 8005710A FR 8005710 A FR8005710 A FR 8005710A FR 2449085 B1 FR2449085 B1 FR 2449085B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8005710A
Other versions
FR2449085A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of FR2449085A1 publication Critical patent/FR2449085A1/fr
Application granted granted Critical
Publication of FR2449085B1 publication Critical patent/FR2449085B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5456—Arylalkanephosphonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
FR8005710A 1978-11-22 1980-03-14 Nouveaux analogues de prostacyclines Granted FR2449085A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96284578A 1978-11-22 1978-11-22
US06/062,443 US4312810A (en) 1978-11-22 1979-07-31 2,5-Inter-o-phenylene-3,4-dinor-5,9α-epoxy-9-deoxy-PGF1 compounds

Publications (2)

Publication Number Publication Date
FR2449085A1 FR2449085A1 (fr) 1980-09-12
FR2449085B1 true FR2449085B1 (fr) 1982-03-12

Family

ID=26742270

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7928709A Granted FR2442235A1 (fr) 1978-11-22 1979-11-21 Analogues et intermediaires de prostacyclines
FR8005710A Granted FR2449085A1 (fr) 1978-11-22 1980-03-14 Nouveaux analogues de prostacyclines

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7928709A Granted FR2442235A1 (fr) 1978-11-22 1979-11-21 Analogues et intermediaires de prostacyclines

Country Status (10)

Country Link
US (1) US4312810A (fr)
AU (1) AU529927B2 (fr)
CA (1) CA1175822A (fr)
CH (2) CH643839A5 (fr)
DE (1) DE2945781A1 (fr)
FR (2) FR2442235A1 (fr)
GB (3) GB2037752B (fr)
IT (1) IT7927410A0 (fr)
NL (1) NL7908484A (fr)
SE (1) SE7909480L (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3029984C2 (de) 1980-08-08 1983-12-15 Grünenthal GmbH, 5190 Stolberg 2-Oxabicyclo [3.3.0] octanderivate und diese enthaltende Arzneimittel
IL65387A0 (en) * 1981-04-14 1982-05-31 Chinoin Gyogyszer Es Vegyeszet 2,3,4-trinor-m-inter-phenylene-prostaglandin derivatives and a process for the preparation thereof
US4401824A (en) * 1982-03-08 1983-08-30 The Upjohn Company Benzopyran compounds, derivatives of prostaglandins
HU192909B (en) * 1985-01-17 1987-07-28 Chinoin Gyogyszer Es Vegyeszet Process for producing interfuranylene-prostacycline derivatives
US5661178A (en) * 1995-09-01 1997-08-26 Allergan Method for effecting vasodilation with (1,5-inter)aryl prostaglandin derivatives
US9890146B2 (en) 2014-02-27 2018-02-13 Ono Pharmaceutical Co., Ltd. Compound having selective EP2 agonist activity
JP6773035B2 (ja) 2015-07-23 2020-10-21 小野薬品工業株式会社 Ｅｐ２アゴニスト活性を有する化合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3728382A (en) * 1970-05-04 1973-04-17 Upjohn Co 15-methyl and 15-ethyl prostaglandin analogs
US3903131A (en) * 1971-04-12 1975-09-02 Upjohn Co 16 and 16,16-dimethyl PGE{HD 2{B
US3962293A (en) * 1973-07-20 1976-06-08 The Upjohn Company 13,14-Dihydro-16-fluoro prostaglandin F1
US4026909A (en) * 1975-07-14 1977-05-31 The Upjohn Company Cis-13-PGF2.sub.α analogs
ZA764727B (en) * 1975-09-02 1977-07-27 Upjohn Co Prostanoic acid derivatives
US4029681A (en) * 1976-02-13 1977-06-14 The Upjohn Company 13,14-Didehydro-PG analogs
US4123441A (en) * 1976-09-22 1978-10-31 The Upjohn Company Enlarged-hetero-ring prostacyclin analogs

Also Published As

Publication number Publication date
IT7927410A0 (it) 1979-11-19
GB2037752A (en) 1980-07-16
FR2449085A1 (fr) 1980-09-12
FR2442235A1 (fr) 1980-06-20
GB2053223A (en) 1981-02-04
AU529927B2 (en) 1983-06-23
CH643828A5 (de) 1984-06-29
SE7909480L (sv) 1980-05-23
CA1175822A (fr) 1984-10-09
GB2053222A (en) 1981-02-04
AU5236879A (en) 1980-05-29
GB2053223B (en) 1982-10-06
GB2037752B (en) 1982-11-03
FR2442235B1 (fr) 1982-12-03
NL7908484A (nl) 1980-05-27
CH643839A5 (de) 1984-06-29
GB2053222B (en) 1982-10-06
DE2945781A1 (de) 1980-06-12
US4312810A (en) 1982-01-26

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Legal Events

Date Code Title Description
ST Notification of lapse