FR2448897A1 - NITROGLYCERIN COMPOSITION FOR DIRECT THERAPEUTIC APPLICATION ON THE SKIN AND PROCESS FOR PREPARING THE SAME - Google Patents

NITROGLYCERIN COMPOSITION FOR DIRECT THERAPEUTIC APPLICATION ON THE SKIN AND PROCESS FOR PREPARING THE SAME

Info

Publication number
FR2448897A1
FR2448897A1 FR8009234A FR8009234A FR2448897A1 FR 2448897 A1 FR2448897 A1 FR 2448897A1 FR 8009234 A FR8009234 A FR 8009234A FR 8009234 A FR8009234 A FR 8009234A FR 2448897 A1 FR2448897 A1 FR 2448897A1
Authority
FR
France
Prior art keywords
skin
composition
weight
preparing
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8009234A
Other languages
French (fr)
Other versions
FR2448897B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Riker Laboratories Inc
Original Assignee
Riker Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Riker Laboratories Inc filed Critical Riker Laboratories Inc
Publication of FR2448897A1 publication Critical patent/FR2448897A1/en
Application granted granted Critical
Publication of FR2448897B1 publication Critical patent/FR2448897B1/fr
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'INVENTION CONCERNE UNE COMPOSITION A BASE DE NITROGLYCERINE DESTINEE A ETRE APPLIQUEE SUR LA PEAU A DES FINS THERAPEUTIQUES. LA COMPOSITION COMPORTE 40 A 90 EN POIDS D'UNE BASE VISQUEUSE GRASSE DU TYPE HUILE EPAISSIE ET 10 A 60 EN POIDS D'UNE POUDRE SOLIDE FORMANT POMMADE QUI CONSISTE EN POLYOLEFINE AYANT ADSORBEE DE LA NITROGLYCERINE DE MANIERE QUE LA TENEUR DE CETTE DERNIERE PAR RAPPORT AU POIDS TOTAL DE LA COMPOSITION SOIT COMPRISE ENTRE 0,5 ET 4 EN POIDS. CETTE COMPOSITION PERMET L'ADMINISTRATION LOCALE PROLONGEE DE DOSES THERAPEUTIQUES DETERMINEES DE NITROGLYCERINE A TRAVERS LA PEAU.THE INVENTION CONCERNS A COMPOSITION BASED ON NITROGLYCERIN INTENDED TO BE APPLIED TO THE SKIN FOR THERAPEUTIC PURPOSES. THE COMPOSITION CONTAINS 40 TO 90 BY WEIGHT OF A FATTY VISCOUS BASE OF THE THICKENED OIL TYPE AND 10 TO 60 BY WEIGHT OF A SOLID POWDER FORMING OINTMENT WHICH CONSISTS OF POLYOLEFIN HAVING ADSORBED NITROGLYCERINE IN SUCH AS THE CONTENT OF THE LATTER THE TOTAL WEIGHT OF THE COMPOSITION IS BETWEEN 0.5 AND 4 BY WEIGHT. THIS COMPOSITION ALLOWS PROLONGED LOCAL ADMINISTRATION OF DETERMINED THERAPEUTIC DOSES OF NITROGLYCERINE THROUGH THE SKIN.

FR8009234A 1978-06-05 1980-04-24 NITROGLYCERIN COMPOSITION FOR DIRECT THERAPEUTIC APPLICATION ON THE SKIN AND PROCESS FOR PREPARING THE SAME Granted FR2448897A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91234678A 1978-06-05 1978-06-05

Publications (2)

Publication Number Publication Date
FR2448897A1 true FR2448897A1 (en) 1980-09-12
FR2448897B1 FR2448897B1 (en) 1983-09-02

Family

ID=25431760

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7914225A Granted FR2435950A1 (en) 1978-06-05 1979-06-01 MEDICAL DRESSING COMPRISING A NITROGLYCERIN COMPOSITION, ITS MANUFACTURE AND ITS APPLICATION
FR8009234A Granted FR2448897A1 (en) 1978-06-05 1980-04-24 NITROGLYCERIN COMPOSITION FOR DIRECT THERAPEUTIC APPLICATION ON THE SKIN AND PROCESS FOR PREPARING THE SAME

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7914225A Granted FR2435950A1 (en) 1978-06-05 1979-06-01 MEDICAL DRESSING COMPRISING A NITROGLYCERIN COMPOSITION, ITS MANUFACTURE AND ITS APPLICATION

Country Status (3)

Country Link
DE (1) DE2922792A1 (en)
FR (2) FR2435950A1 (en)
GB (1) GB2021950B (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4291014A (en) 1979-01-11 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing estradiol diacetate
IL59063A (en) * 1979-01-11 1983-12-30 Key Pharma Polymeric diffusion matrix for release of pharmaceutical dosage
US4291015A (en) 1979-08-14 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing a vasodilator
US4286592A (en) * 1980-02-04 1981-09-01 Alza Corporation Therapeutic system for administering drugs to the skin
JPS56133381A (en) * 1980-03-25 1981-10-19 Nippon Kayaku Co Ltd Pressure-sensitive adhesive tape or sheet containing nitroglycerin
CA1163195A (en) * 1980-06-26 1984-03-06 Alec D. Keith Polymeric diffusion matrix containing a vasodilator
JPS5759806A (en) * 1980-08-11 1982-04-10 Searle & Co Nitroglycerine pad for percutaneous administration
US4336243A (en) * 1980-08-11 1982-06-22 G. D. Searle & Co. Transdermal nitroglycerin pad
JPS5777617A (en) * 1980-10-20 1982-05-15 Nichiban Co Ltd Plaster for cardiac disease
IL61721A (en) * 1980-12-16 1984-03-30 Blank Izhak Nitroglycerin preparations
JPS57116011A (en) * 1981-01-08 1982-07-19 Nitto Electric Ind Co Ltd Pharmaceutical preparation
US4725272A (en) * 1981-06-29 1988-02-16 Alza Corporation Novel bandage for administering beneficial drug
GB2105990B (en) * 1981-08-27 1985-06-19 Nitto Electric Ind Co Adhesive skin patches
US4460562A (en) * 1982-01-06 1984-07-17 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing propranolol
US4559222A (en) * 1983-05-04 1985-12-17 Alza Corporation Matrix composition for transdermal therapeutic system
US4696821A (en) * 1983-10-11 1987-09-29 Warner-Lambert Company Transdermal delivery system for administration of nitroglycerin
DE3347277A1 (en) * 1983-12-28 1985-07-11 Bayer Ag, 5090 Leverkusen ACTIVE SUBSTANCE DELIVERY SYSTEMS
DE3347278A1 (en) * 1983-12-28 1985-07-11 Bayer Ag, 5090 Leverkusen ACTIVE SUBSTANCE DELIVERY SYSTEMS
CA1256772A (en) * 1985-02-26 1989-07-04 Sudhakar S. Wagle Bandage for the topical administration of controlled amounts of nitroglycerin ointment
DE3518707A1 (en) * 1985-05-24 1986-11-27 Beiersdorf Ag, 2000 Hamburg NITRO PLASTER
US4764381A (en) * 1985-12-06 1988-08-16 Key Pharmaceuticals, Inc. Percutaneous penetration enhancer of oleic acid and 2-ethyl-1, 3-hexanediol
DE3634016A1 (en) * 1986-04-17 1987-10-29 Lohmann Gmbh & Co Kg AREA-BASED THERAPEUTIC SYSTEM, METHOD FOR THE PRODUCTION THEREOF AND ITS USE
US4906475A (en) 1988-02-16 1990-03-06 Paco Pharmaceutical Services Estradiol transdermal delivery system
DE4301781C2 (en) * 1993-01-23 1995-07-20 Lohmann Therapie Syst Lts Patch containing nitroglycerin, process for its production and use
GB2292520B (en) * 1994-08-25 1998-09-02 Univ Sheffield Transdermal dressings for animals

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2285896A1 (en) * 1974-09-24 1976-04-23 Nippon Kayaku Kk PHARMACEUTICAL PREPARATION INTENDED FOR ADMINISTRATION IN THE ORAL CAVITY
FR2357244A1 (en) * 1975-03-24 1978-02-03 Minnesota Mining & Mfg NON-GREASY COMPOSITIONS FOR PHARMACY AND COSMETICS

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
US3996934A (en) * 1971-08-09 1976-12-14 Alza Corporation Medical bandage

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2285896A1 (en) * 1974-09-24 1976-04-23 Nippon Kayaku Kk PHARMACEUTICAL PREPARATION INTENDED FOR ADMINISTRATION IN THE ORAL CAVITY
FR2357244A1 (en) * 1975-03-24 1978-02-03 Minnesota Mining & Mfg NON-GREASY COMPOSITIONS FOR PHARMACY AND COSMETICS
GB1503444A (en) * 1975-03-24 1978-03-08 Minnesota Mining & Mfg Non-greasy compositions

Also Published As

Publication number Publication date
GB2021950B (en) 1983-02-23
DE2922792A1 (en) 1979-12-06
FR2448897B1 (en) 1983-09-02
FR2435950B1 (en) 1984-10-19
FR2435950A1 (en) 1980-04-11
GB2021950A (en) 1979-12-12

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Legal Events

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ST Notification of lapse