GB2021950A - Nitroglycerin carriers and bandages - Google Patents

Nitroglycerin carriers and bandages

Info

Publication number
GB2021950A
GB2021950A GB7919544A GB7919544A GB2021950A GB 2021950 A GB2021950 A GB 2021950A GB 7919544 A GB7919544 A GB 7919544A GB 7919544 A GB7919544 A GB 7919544A GB 2021950 A GB2021950 A GB 2021950A
Authority
GB
United Kingdom
Prior art keywords
nitroglycerin
ointment
skin
parts
carrier
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7919544A
Other versions
GB2021950B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Riker Laboratories Inc
Original Assignee
Riker Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Riker Laboratories Inc filed Critical Riker Laboratories Inc
Publication of GB2021950A publication Critical patent/GB2021950A/en
Application granted granted Critical
Publication of GB2021950B publication Critical patent/GB2021950B/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates

Abstract

A nitroglycerin carrier comprises a polymeric ointment-forming powder having nitroglycerin adsorbed upon the particles thereof in the amount of about 1 to 20 parts of nitroglycerin per 100 parts of the total carrier. Formulations comprise from 40 to 90 wt.% of viscous greasy base and form 60 to 10 wt.% of ointment-forming powder carrying nitroglycerin. A bandage has a surface bearing a medicament supply containing nitroglycerin together with a carrier medium which is permeable to the passage of nitroglycerin, the medicament supply being adapted to be held in direct contact with the skin and being capable of supporting a substantially constant rate of nitroglycerin absorption through the skin for at least about eight hours.
GB7919544A 1978-06-05 1979-06-05 Nitroglycerin carriers and bandages Expired GB2021950B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91234678A 1978-06-05 1978-06-05

Publications (2)

Publication Number Publication Date
GB2021950A true GB2021950A (en) 1979-12-12
GB2021950B GB2021950B (en) 1983-02-23

Family

ID=25431760

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7919544A Expired GB2021950B (en) 1978-06-05 1979-06-05 Nitroglycerin carriers and bandages

Country Status (3)

Country Link
DE (1) DE2922792A1 (en)
FR (2) FR2435950A1 (en)
GB (1) GB2021950B (en)

Cited By (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0013606A2 (en) * 1979-01-11 1980-07-23 Key Pharmaceuticals, Inc. Drug delivery device and method for its preparation
EP0033615A2 (en) * 1980-02-04 1981-08-12 Alza Corporation Therapeutic system for administering drugs to the skin
US4291015A (en) 1979-08-14 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing a vasodilator
US4291014A (en) 1979-01-11 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing estradiol diacetate
FR2479089A1 (en) * 1980-03-25 1981-10-02 Nippon Kayaku Kk SELF-ADHESIVE ADHESIVE TAPE OR SHEET CONTAINING NITROGLYCERIN AND METHODS OF PREPARING THE SAME
WO1982000005A1 (en) * 1980-06-26 1982-01-07 Key Pharma Polymeric diffusion matrix containing a vasodilator
FR2488134A1 (en) * 1980-08-11 1982-02-12 Searle & Co TRANSDERMAL NITROGLYCERIN BUFFER
JPS5759806A (en) * 1980-08-11 1982-04-10 Searle & Co Nitroglycerine pad for percutaneous administration
EP0054279A2 (en) * 1980-12-16 1982-06-23 Forest Laboratories, Inc. Composition with sustained release of nitroglycerine, and method of preparing it
EP0062682A1 (en) * 1980-10-20 1982-10-20 Nichiban Co. Ltd. Adhesive preparation for heart disease and process for its preparation
FR2508318A1 (en) * 1981-06-29 1982-12-31 Alza Corp BANDAGE FOR THE ADMINISTRATION OF A PHARMACEUTICAL SUBSTANCE
US4420470A (en) * 1981-01-08 1983-12-13 Nitto Electric Industrial Co., Ltd. Percutaneous absorption type pharmaceutical preparation of isosorbide dinitrate or pentaerythritol tetranitrate in pressure-sensitive laminate
US4460562A (en) * 1982-01-06 1984-07-17 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing propranolol
EP0138551A2 (en) * 1983-10-11 1985-04-24 Warner-Lambert Company A system for the transdermal delivery of nitroglycerin
EP0150426A2 (en) * 1983-12-28 1985-08-07 Bayer Ag Delivery system for an active substance
EP0150428A2 (en) * 1983-12-28 1985-08-07 Bayer Ag Delivery system for an active substance
US4559222A (en) * 1983-05-04 1985-12-17 Alza Corporation Matrix composition for transdermal therapeutic system
DE3518707A1 (en) * 1985-05-24 1986-11-27 Beiersdorf Ag, 2000 Hamburg NITRO PLASTER
WO1987003490A2 (en) * 1985-12-06 1987-06-18 Key Pharmaceuticals, Inc. Transdermal delivery system
WO1987006144A1 (en) * 1986-04-17 1987-10-22 Lohmann Gmbh & Co. Kg. Planar therapeutic system, process for its production and its utilization
AU578719B2 (en) * 1985-02-26 1988-11-03 Rorer International (Overseas) Inc. Patch dressing for the administration of controlled amounts of ointment
US5151271A (en) * 1981-08-27 1992-09-29 Nitti Electric Industrial Co., Ltd. Pressure-sensitively adhering composite medicinal preparation
GB2292520A (en) * 1994-08-25 1996-02-28 Univ Sheffield Transdermal dressings for animals

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4906475A (en) 1988-02-16 1990-03-06 Paco Pharmaceutical Services Estradiol transdermal delivery system
DE4301781C2 (en) * 1993-01-23 1995-07-20 Lohmann Therapie Syst Lts Patch containing nitroglycerin, process for its production and use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
US3996934A (en) * 1971-08-09 1976-12-14 Alza Corporation Medical bandage
JPS5138412A (en) * 1974-09-24 1976-03-31 Nippon Kayaku Kk Kokoseizai no seiho
US4164563A (en) * 1975-03-24 1979-08-14 Minnesota Mining And Manufacturing Company Non-greasy compositions

Cited By (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4291014A (en) 1979-01-11 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing estradiol diacetate
EP0013606A3 (en) * 1979-01-11 1981-01-07 Key Pharmaceuticals, Inc. Polymeric diffusion matrix, method of its preparation and drug delivery device comprising said matrix
EP0013606A2 (en) * 1979-01-11 1980-07-23 Key Pharmaceuticals, Inc. Drug delivery device and method for its preparation
US4292303A (en) 1979-08-14 1981-09-29 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing clonidine
US4291015A (en) 1979-08-14 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing a vasodilator
US4292301A (en) 1979-08-14 1981-09-29 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing ephedrine
US4492685A (en) * 1979-08-14 1985-01-08 Key Pharmaceuticals, Inc. Protective skin matrix
US4292302A (en) 1979-08-14 1981-09-29 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing terbutaline
US4294820A (en) 1979-08-14 1981-10-13 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing phenylephrine
EP0033615A3 (en) * 1980-02-04 1982-01-20 Alza Corporation Therapeutic system for administering drugs to the skin
EP0033615A2 (en) * 1980-02-04 1981-08-12 Alza Corporation Therapeutic system for administering drugs to the skin
FR2479089A1 (en) * 1980-03-25 1981-10-02 Nippon Kayaku Kk SELF-ADHESIVE ADHESIVE TAPE OR SHEET CONTAINING NITROGLYCERIN AND METHODS OF PREPARING THE SAME
WO1982000005A1 (en) * 1980-06-26 1982-01-07 Key Pharma Polymeric diffusion matrix containing a vasodilator
FR2488134A1 (en) * 1980-08-11 1982-02-12 Searle & Co TRANSDERMAL NITROGLYCERIN BUFFER
JPS5759806A (en) * 1980-08-11 1982-04-10 Searle & Co Nitroglycerine pad for percutaneous administration
JPH0226602B2 (en) * 1980-08-11 1990-06-12 Searle & Co
EP0062682A1 (en) * 1980-10-20 1982-10-20 Nichiban Co. Ltd. Adhesive preparation for heart disease and process for its preparation
EP0062682A4 (en) * 1980-10-20 1983-09-20 Nichiban Kk Adhesive preparation for heart disease and process for its preparation.
EP0054279A2 (en) * 1980-12-16 1982-06-23 Forest Laboratories, Inc. Composition with sustained release of nitroglycerine, and method of preparing it
EP0054279A3 (en) * 1980-12-16 1982-09-22 Forest Laboratories, Inc. Composition with sustained release of nitroglycerine, and method of preparing it
US4420470A (en) * 1981-01-08 1983-12-13 Nitto Electric Industrial Co., Ltd. Percutaneous absorption type pharmaceutical preparation of isosorbide dinitrate or pentaerythritol tetranitrate in pressure-sensitive laminate
FR2508318A1 (en) * 1981-06-29 1982-12-31 Alza Corp BANDAGE FOR THE ADMINISTRATION OF A PHARMACEUTICAL SUBSTANCE
US5151271A (en) * 1981-08-27 1992-09-29 Nitti Electric Industrial Co., Ltd. Pressure-sensitively adhering composite medicinal preparation
US4460562A (en) * 1982-01-06 1984-07-17 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing propranolol
US4559222A (en) * 1983-05-04 1985-12-17 Alza Corporation Matrix composition for transdermal therapeutic system
EP0138551A2 (en) * 1983-10-11 1985-04-24 Warner-Lambert Company A system for the transdermal delivery of nitroglycerin
EP0138551A3 (en) * 1983-10-11 1987-01-14 Warner-Lambert Company A system for the transdermal delivery of nitroglycerin
EP0150426A3 (en) * 1983-12-28 1986-01-15 Bayer Ag Delivery system for an active substance
US4627852A (en) * 1983-12-28 1986-12-09 Bayer Aktiengesellschaft Active compound release systems
US4661104A (en) * 1983-12-28 1987-04-28 Bayer Aktiengesellschaft Active compound release systems
EP0150426A2 (en) * 1983-12-28 1985-08-07 Bayer Ag Delivery system for an active substance
EP0150428A3 (en) * 1983-12-28 1986-01-15 Bayer Ag Delivery system for an active substance
EP0150428A2 (en) * 1983-12-28 1985-08-07 Bayer Ag Delivery system for an active substance
AU578719B2 (en) * 1985-02-26 1988-11-03 Rorer International (Overseas) Inc. Patch dressing for the administration of controlled amounts of ointment
DE3518707A1 (en) * 1985-05-24 1986-11-27 Beiersdorf Ag, 2000 Hamburg NITRO PLASTER
EP0393727A2 (en) * 1985-12-06 1990-10-24 Key Pharmaceuticals, Inc. Transdermal delivery system
WO1987003490A3 (en) * 1985-12-06 1987-07-30 Key Pharma Transdermal delivery system
EP0393727A3 (en) * 1985-12-06 1990-11-22 Key Pharmaceuticals, Inc. Transdermal delivery system
WO1987003490A2 (en) * 1985-12-06 1987-06-18 Key Pharmaceuticals, Inc. Transdermal delivery system
EP0242827A1 (en) * 1986-04-17 1987-10-28 Lohmann GmbH & Co. KG Surface shaped therapeutic system, method for its manufacture, and its application
WO1987006144A1 (en) * 1986-04-17 1987-10-22 Lohmann Gmbh & Co. Kg. Planar therapeutic system, process for its production and its utilization
GB2292520A (en) * 1994-08-25 1996-02-28 Univ Sheffield Transdermal dressings for animals
GB2292520B (en) * 1994-08-25 1998-09-02 Univ Sheffield Transdermal dressings for animals
US5981579A (en) * 1994-08-25 1999-11-09 The University Of Sheffield Use of nitrovasodilators for treatment of disease or stress conditions in a non-human mammal

Also Published As

Publication number Publication date
FR2448897B1 (en) 1983-09-02
DE2922792A1 (en) 1979-12-06
GB2021950B (en) 1983-02-23
FR2435950A1 (en) 1980-04-11
FR2448897A1 (en) 1980-09-12
FR2435950B1 (en) 1984-10-19

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee