FR2446280A1 - Arylthio-3 hydroxy-4 pyrrolidines 1-substituees et leurs derives, utiles comme medicaments - Google Patents

Arylthio-3 hydroxy-4 pyrrolidines 1-substituees et leurs derives, utiles comme medicaments

Info

Publication number
FR2446280A1
FR2446280A1 FR8000270A FR8000270A FR2446280A1 FR 2446280 A1 FR2446280 A1 FR 2446280A1 FR 8000270 A FR8000270 A FR 8000270A FR 8000270 A FR8000270 A FR 8000270A FR 2446280 A1 FR2446280 A1 FR 2446280A1
Authority
FR
France
Prior art keywords
pyrrolidines
medicaments
hydroxy
derivatives
useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8000270A
Other languages
English (en)
French (fr)
Other versions
FR2446280B1 (US06818201-20041116-C00086.png
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AH Robins Co Inc
Original Assignee
AH Robins Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AH Robins Co Inc filed Critical AH Robins Co Inc
Publication of FR2446280A1 publication Critical patent/FR2446280A1/fr
Application granted granted Critical
Publication of FR2446280B1 publication Critical patent/FR2446280B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
FR8000270A 1979-01-09 1980-01-08 Arylthio-3 hydroxy-4 pyrrolidines 1-substituees et leurs derives, utiles comme medicaments Granted FR2446280A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/002,103 US4251541A (en) 1979-01-09 1979-01-09 1-Substituted-3-arylthio-4-hydroxypyrrolidines

Publications (2)

Publication Number Publication Date
FR2446280A1 true FR2446280A1 (fr) 1980-08-08
FR2446280B1 FR2446280B1 (US06818201-20041116-C00086.png) 1983-06-10

Family

ID=21699258

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8000270A Granted FR2446280A1 (fr) 1979-01-09 1980-01-08 Arylthio-3 hydroxy-4 pyrrolidines 1-substituees et leurs derives, utiles comme medicaments

Country Status (10)

Country Link
US (1) US4251541A (US06818201-20041116-C00086.png)
JP (1) JPS5598159A (US06818201-20041116-C00086.png)
CA (1) CA1133912A (US06818201-20041116-C00086.png)
CH (1) CH644361A5 (US06818201-20041116-C00086.png)
DE (1) DE3000623A1 (US06818201-20041116-C00086.png)
FR (1) FR2446280A1 (US06818201-20041116-C00086.png)
GB (1) GB2040931B (US06818201-20041116-C00086.png)
IT (1) IT1130215B (US06818201-20041116-C00086.png)
MX (1) MX6772E (US06818201-20041116-C00086.png)
SE (1) SE435926B (US06818201-20041116-C00086.png)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE45511B1 (en) * 1976-09-01 1982-09-08 Ciba Geigy Ag New derivatives of perhydro-aza-heterocycles and processesfor the production thereof
US5360798A (en) * 1991-07-04 1994-11-01 Shionogi Seiyaku Kabushiki Kaisha Aminooxypyrrolidinylthiocarbapenem compounds
CN101182304B (zh) * 2007-11-30 2010-05-12 山东金城医药化工股份有限公司 吡咯烷或n-烷基吡咯烷的制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1514848A (fr) * 1966-09-30 1968-02-23 Robins Co Inc A H Procédé de préparation des pyrrolidinols o-substitués et thiopyrrolidinols s-substitués
CH521338A (de) * 1967-03-13 1972-04-15 Robins Co Inc A H Verfahren zur Herstellung von neuen Pyrrolidinderivaten
DE2738477A1 (de) * 1976-09-01 1978-03-02 Ciba Geigy Ag Neue derivate von perhydro-aza- heterocyclen und verfahren zu ihrer herstellung

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3577415A (en) * 1968-12-23 1971-05-04 Robins Co Inc A H 1-substituted-3-substituted phenoxypyrrolidines

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1514848A (fr) * 1966-09-30 1968-02-23 Robins Co Inc A H Procédé de préparation des pyrrolidinols o-substitués et thiopyrrolidinols s-substitués
CH521338A (de) * 1967-03-13 1972-04-15 Robins Co Inc A H Verfahren zur Herstellung von neuen Pyrrolidinderivaten
DE2738477A1 (de) * 1976-09-01 1978-03-02 Ciba Geigy Ag Neue derivate von perhydro-aza- heterocyclen und verfahren zu ihrer herstellung
FR2363559A1 (fr) * 1976-09-01 1978-03-31 Ciba Geigy Ag Nouveaux derives de perhydro-aza-heterocycles utiles comme medicaments et procede pour leur preparation

Also Published As

Publication number Publication date
IT1130215B (it) 1986-06-11
CH644361A5 (fr) 1984-07-31
JPS648620B2 (US06818201-20041116-C00086.png) 1989-02-14
JPS5598159A (en) 1980-07-25
US4251541A (en) 1981-02-17
FR2446280B1 (US06818201-20041116-C00086.png) 1983-06-10
CA1133912A (en) 1982-10-19
GB2040931A (en) 1980-09-03
GB2040931B (en) 1983-04-13
DE3000623A1 (de) 1980-07-17
SE8000084L (sv) 1980-07-10
IT8019100A0 (it) 1980-01-09
SE435926B (sv) 1984-10-29
MX6772E (es) 1986-07-09

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Legal Events

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