FR2442238A1 - Procede d'obtention d'ajmalicine et des sels d'addition acide de celle-ci - Google Patents

Procede d'obtention d'ajmalicine et des sels d'addition acide de celle-ci

Info

Publication number
FR2442238A1
FR2442238A1 FR7929088A FR7929088A FR2442238A1 FR 2442238 A1 FR2442238 A1 FR 2442238A1 FR 7929088 A FR7929088 A FR 7929088A FR 7929088 A FR7929088 A FR 7929088A FR 2442238 A1 FR2442238 A1 FR 2442238A1
Authority
FR
France
Prior art keywords
hydrocarbon
isolation
extn
pref
opt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7929088A
Other languages
English (en)
Other versions
FR2442238B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of FR2442238A1 publication Critical patent/FR2442238A1/fr
Application granted granted Critical
Publication of FR2442238B1 publication Critical patent/FR2442238B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Nouveau procédé d'obtention d'ajmalicine à partir des racines de plantes Catharanthus roseus. Le procédé consiste à extraire les racines à l'aide d'un alcanol contenant de 1 à 5 atomes de carbone, à additionner l'extrait d'une solution aqueuse d'un acide faible, à extraire ce mélange d'abord avec un hydrocarbure, ensuite avec un hydrocarbure chloré ou un ester, à isoler si on le désire de la solution d'hydrocarbure la tétrahydroalstonine et à isoler à partir de l'extrait obtenu à l'aide de l'hydrocarbure chloré ou à partir d'un ester, l'ajmalicine d'une manière connue en soi.
FR7929088A 1978-11-27 1979-11-26 Procede d'obtention d'ajmalicine et des sels d'addition acide de celle-ci Granted FR2442238A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HURI000688 HU179055B (en) 1978-11-27 1978-11-27 New process for separating ajmalicin and acid additional salts

Publications (2)

Publication Number Publication Date
FR2442238A1 true FR2442238A1 (fr) 1980-06-20
FR2442238B1 FR2442238B1 (fr) 1983-06-17

Family

ID=11001075

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7929088A Granted FR2442238A1 (fr) 1978-11-27 1979-11-26 Procede d'obtention d'ajmalicine et des sels d'addition acide de celle-ci

Country Status (3)

Country Link
DE (1) DE2947532A1 (fr)
FR (1) FR2442238A1 (fr)
HU (1) HU179055B (fr)

Also Published As

Publication number Publication date
FR2442238B1 (fr) 1983-06-17
HU179055B (en) 1982-08-28
DE2947532A1 (de) 1980-10-16

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Legal Events

Date Code Title Description
ST Notification of lapse