FR2438657A1 - Procede de preparation de derives de 9h-pyrido(3,4-b)indole et nouveaux produits ainsi obtenus, a activite d'inhibition de xanthine-oxydase - Google Patents

Procede de preparation de derives de 9h-pyrido(3,4-b)indole et nouveaux produits ainsi obtenus, a activite d'inhibition de xanthine-oxydase

Info

Publication number
FR2438657A1
FR2438657A1 FR7924126A FR7924126A FR2438657A1 FR 2438657 A1 FR2438657 A1 FR 2438657A1 FR 7924126 A FR7924126 A FR 7924126A FR 7924126 A FR7924126 A FR 7924126A FR 2438657 A1 FR2438657 A1 FR 2438657A1
Authority
FR
France
Prior art keywords
derivatives
xanthine oxidase
indole
inhibition activity
pyrido
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7924126A
Other languages
English (en)
Other versions
FR2438657B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Shinyaku Co Ltd
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Publication of FR2438657A1 publication Critical patent/FR2438657A1/fr
Application granted granted Critical
Publication of FR2438657B1 publication Critical patent/FR2438657B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDE DE PREPARATION DE DERIVES DE 9H-PYRIDO3,4-BINDOLE ET NOUVEAUX PRODUITS AINSI OBTENUS. CES DERIVES ONT LA FORMULE: (CF DESSIN DANS BOPI) OU R ET R RESPECTIVEMENT REPRESENTENT H, OH, UN GROUPE ACYLOXY, OU TOSYLOXY ET R EST LE GROUPE HYDROXYMETHYLE, CARBOXY, CARBO-ALCOXY OU FORMYLE. LA PRESENTE INVENTION EST PARTICULIEREMENT UTILE POUR FOURNIR DES DERIVES D'INDOLE, PRESENTANT NOTAMMENT UNE ACTIVITE D'INHIBITION DE LA XANTHINE-OXYDASE ET UNE ACTIVITE ANTITUMEUR.
FR7924126A 1978-10-14 1979-09-27 Procede de preparation de derives de 9h-pyrido(3,4-b)indole et nouveaux produits ainsi obtenus, a activite d'inhibition de xanthine-oxydase Granted FR2438657A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP53126352A JPS5936919B2 (ja) 1978-10-14 1978-10-14 インド−ル誘導体

Publications (2)

Publication Number Publication Date
FR2438657A1 true FR2438657A1 (fr) 1980-05-09
FR2438657B1 FR2438657B1 (fr) 1983-02-18

Family

ID=14933044

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7924126A Granted FR2438657A1 (fr) 1978-10-14 1979-09-27 Procede de preparation de derives de 9h-pyrido(3,4-b)indole et nouveaux produits ainsi obtenus, a activite d'inhibition de xanthine-oxydase

Country Status (7)

Country Link
US (1) US4241064A (fr)
JP (1) JPS5936919B2 (fr)
CH (1) CH644121A5 (fr)
DE (1) DE2941449C2 (fr)
FR (1) FR2438657A1 (fr)
GB (1) GB2031882B (fr)
IT (1) IT1164906B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5331006A (en) * 1990-08-31 1994-07-19 Warner-Lambert Company Amino acid analogs as CCK antagonists
WO1992004025A1 (fr) * 1990-08-31 1992-03-19 Warner-Lambert Company Analogues d'acides amines utilises comme antagonistes de cholecystokinine
EP1044002A4 (fr) 1997-11-07 2003-05-02 Univ Johns Hopkins Procedes de traitement de troubles de la contractilite cardiaque
KR20070053231A (ko) 2004-07-28 2007-05-23 다케다 야쿠힌 고교 가부시키가이샤 피롤로[2,3-ｃ]피리딘 화합물, 그 제조 방법 및 용도
US8841333B2 (en) 2005-05-09 2014-09-23 Takeda Pharmaceuticals U.S.A., Inc. Methods for treating nephrolithiasis
EP1954290B1 (fr) * 2005-11-22 2012-07-25 Merck Sharp & Dohme Corp. Composes tricycliques utilises comme inhibiteurs de kinases
KR101797936B1 (ko) 2010-09-10 2017-11-15 다케다 파마슈티칼스 유에스에이, 인코포레이티드 테오필린과 페북소스타트의 병용 치료 방법
JP6472428B2 (ja) * 2015-12-09 2019-02-20 財團法人食品工業發展研究所 キサンチンオキシダーゼ活性の阻害におけるβ−カルボリンアルカロイドの使用

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CA1968 *
CA1972 *
CA1973 *

Also Published As

Publication number Publication date
FR2438657B1 (fr) 1983-02-18
JPS5555187A (en) 1980-04-22
IT7950505A0 (it) 1979-10-09
DE2941449A1 (de) 1980-04-17
US4241064A (en) 1980-12-23
GB2031882A (en) 1980-04-30
CH644121A5 (de) 1984-07-13
JPS5936919B2 (ja) 1984-09-06
DE2941449C2 (de) 1985-08-14
IT1164906B (it) 1987-04-15
GB2031882B (en) 1983-05-18

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Legal Events

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