FR2432521B1 - - Google Patents

Info

Publication number
FR2432521B1
FR2432521B1 FR7809617A FR7809617A FR2432521B1 FR 2432521 B1 FR2432521 B1 FR 2432521B1 FR 7809617 A FR7809617 A FR 7809617A FR 7809617 A FR7809617 A FR 7809617A FR 2432521 B1 FR2432521 B1 FR 2432521B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7809617A
Other languages
French (fr)
Other versions
FR2432521A1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7809617A priority Critical patent/FR2432521A1/en
Priority to FR7824563A priority patent/FR2438050A2/en
Priority to FR7901611A priority patent/FR2447380A2/en
Priority to SE7901203A priority patent/SE448379B/en
Priority to ZA791473A priority patent/ZA791473B/en
Priority to ES479037A priority patent/ES479037A1/en
Priority to JP3717479A priority patent/JPS54132593A/en
Priority to AT0240379A priority patent/AT367423B/en
Priority to DK130878A priority patent/DK130879A/en
Priority to AU45666/79A priority patent/AU526990B2/en
Priority to PT69421A priority patent/PT69421A/en
Priority to IT48557/79A priority patent/IT1120404B/en
Priority to DE19792912829 priority patent/DE2912829A1/en
Priority to CH300879A priority patent/CH638811A5/en
Priority to LU81104A priority patent/LU81104A1/en
Priority to GB7911275A priority patent/GB2017702B/en
Priority to BE0/194319A priority patent/BE875217A/en
Priority to CA000324690A priority patent/CA1152061A/en
Priority to GB08134540A priority patent/GB2101117B/en
Priority to NL7902555A priority patent/NL7902555A/en
Priority to IE24385A priority patent/IE49868B1/en
Priority to IE85279A priority patent/IE49867B1/en
Priority to FR8001300A priority patent/FR2474034A2/en
Publication of FR2432521A1 publication Critical patent/FR2432521A1/en
Priority to AT4381A priority patent/AT371472B/en
Priority to US06/267,638 priority patent/US4439433A/en
Application granted granted Critical
Publication of FR2432521B1 publication Critical patent/FR2432521B1/fr
Priority to CH194983A priority patent/CH642648A5/en
Priority to FR8316698A priority patent/FR2553770B2/en
Priority to JP1250789A priority patent/JPH02138283A/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
FR7809617A 1978-03-31 1978-03-31 NOVEL O-SUBSTITUTED OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR USE AS MEDICAMENTS Granted FR2432521A1 (en)

Priority Applications (28)

Application Number Priority Date Filing Date Title
FR7809617A FR2432521A1 (en) 1978-03-31 1978-03-31 NOVEL O-SUBSTITUTED OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR USE AS MEDICAMENTS
FR7824563A FR2438050A2 (en) 1978-03-31 1978-08-24 NOVEL O-SUBSTITUTED OXIMES DERIVED FROM 7-AMINOTHIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
FR7901611A FR2447380A2 (en) 1978-03-31 1979-01-23 NOVEL O-SUBSTITUTED OXIMES DERIVED FROM 7-AMINOTHIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
SE7901203A SE448379B (en) 1978-03-31 1979-02-12 O-SUBSTITUTED OXIME DERIVATIVES OF 7-AMINO-THIAZOLYL-ACETAMIDOCEPHALOSPORANIC ACID
ZA791473A ZA791473B (en) 1978-03-31 1979-03-28 New o-substituted oxime derivatives of 7-amino thiazolyl acetamido cephalosporanic acid,process for preparing them,their use as medicaments and the pharmaceutical compositions containing them
ES479037A ES479037A1 (en) 1978-03-31 1979-03-29 Oximes
GB7911275A GB2017702B (en) 1978-03-31 1979-03-30 O-substituted oxime derivatives of 7-((2-(2-aminothiazol 4-yl)-2-hydroxyiminoacetyl)-amino)-ceph-3-em-4-carboxylic acid
DK130878A DK130879A (en) 1978-03-31 1979-03-30 PROCEDURE FOR THE PREPARATION OF NOW UNKNOWN OXIMIDE DERIVATIVES OF 7-AMINOTHIAZOLYLACETAMIDOCEPHALOSPORANIC ACID
AU45666/79A AU526990B2 (en) 1978-03-31 1979-03-30 O-substituted oxime derivatives
PT69421A PT69421A (en) 1978-03-31 1979-03-30 PROCESS FOR THE PREPARATION OF NEW OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID
IT48557/79A IT1120404B (en) 1978-03-31 1979-03-30 OXIMATE O-SUBSTITUTES DERIVED FROM CIDO 7-AMINO THIAZOLYL ACETAMIDE CEPHALOSPORANIC PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR PREPARATION PROCEDURE
DE19792912829 DE2912829A1 (en) 1978-03-31 1979-03-30 O-SUBSTITUTED OXIME DERIVATIVES OF 7-AMINOTIAOYL-ACETAMIDO-CEPHALOSPORANIC ACID, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS
CH300879A CH638811A5 (en) 1978-03-31 1979-03-30 O-SUBSTITUTED OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
LU81104A LU81104A1 (en) 1978-03-31 1979-03-30 NEW O-SUBSTITUTED OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS, THEIR APPLICATION AS MEDICINAL PRODUCTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
JP3717479A JPS54132593A (en) 1978-03-31 1979-03-30 Novel oosubstituted oxime derivatives of 77aminothiazolylacetoamidecephalosporanic acid*their manufacture*their use as drug and composition containing them
BE0/194319A BE875217A (en) 1978-03-31 1979-03-30 NEW O-SUBSTITUTED OXIMES OF 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANQUE, THEIR PREPARATION PROCESS, THEIR APPLICATION AS MEDICINAL PRODUCTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
CA000324690A CA1152061A (en) 1978-03-31 1979-03-30 Process for preparing new o-substituted amino-7 thiazolyl acetamido cephalospranic acide derivatives
GB08134540A GB2101117B (en) 1978-03-31 1979-03-30 New o-substituted oxime derivatives of 2-amino-thiazol-4-yl-2-hydroxyimino acetic acid
AT0240379A AT367423B (en) 1978-03-31 1979-03-30 METHOD FOR PRODUCING NEW OXIME DERIVATIVES OF 7-AMINOTHIAZOLYLACETAMIDOCEPHALOSPORANS [URE
NL7902555A NL7902555A (en) 1978-03-31 1979-04-02 NEW 0-SUBSTITUTED OXIM COMPOUNDS OF 7-AMINO-THIAZOLYLACEETAMIDOCEPHALOSPORANIC ACID, METHOD FOR THEIR PREPARATION, THEIR USE AS MEDICINAL PRODUCTS AND PHARMACEUTICAL COMPOSITIONS THEREFORE OBTAINED.
IE24385A IE49868B1 (en) 1978-03-31 1979-08-08 New o-substituted oxime derivatives of 2-amino-thiazol-4-yl-2-hydroxyimino acetic acid
IE85279A IE49867B1 (en) 1978-03-31 1979-08-08 O-substituted oxime derivatives of 7-((2-(2-aminothiazol-4-yl)-2-hydroxyimino-acetyl)-amino)-ceph-3-em-4-carboxylic acid
FR8001300A FR2474034A2 (en) 1978-03-31 1980-01-22 NOVEL 0-SUBSTITUTED OXIMES DERIVED FROM 7-AMINOTHIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, PROCESS FOR PREPARING THEM AND THEIR APPLICATION AS MEDICAMENTS
AT4381A AT371472B (en) 1978-03-31 1981-01-08 METHOD FOR PRODUCING NEW OXIME DERIVATIVES OF 7-AMINOTHIAZOLYLACETAMIDOCEPHALOSPORANIC ACID
US06/267,638 US4439433A (en) 1978-03-31 1981-05-27 Oximes
CH194983A CH642648A5 (en) 1978-03-31 1983-04-11 2- (AMINOTHIAZOLYL) 2-HYDROXYIMINO ACETIC ACID DERIVATIVES.
FR8316698A FR2553770B2 (en) 1978-03-31 1983-10-20 NOVEL PRODUCTS DERIVED FROM ACID 2 (2-AMINO THIAZOL-4-YL) 2-ALCOXY-IMINO ACETIC SUBSTITUTED ON OXIME AND THEIR PREPARATION PROCESS
JP1250789A JPH02138283A (en) 1978-03-31 1989-09-28 Novel o-substituted oxime derivative of 7-aminothiazolylacetamidocephalosporanic acid

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR7809617A FR2432521A1 (en) 1978-03-31 1978-03-31 NOVEL O-SUBSTITUTED OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR USE AS MEDICAMENTS
FR7824563A FR2438050A2 (en) 1978-03-31 1978-08-24 NOVEL O-SUBSTITUTED OXIMES DERIVED FROM 7-AMINOTHIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
FR7901611A FR2447380A2 (en) 1978-03-31 1979-01-23 NOVEL O-SUBSTITUTED OXIMES DERIVED FROM 7-AMINOTHIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
FR8001300A FR2474034A2 (en) 1978-03-31 1980-01-22 NOVEL 0-SUBSTITUTED OXIMES DERIVED FROM 7-AMINOTHIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, PROCESS FOR PREPARING THEM AND THEIR APPLICATION AS MEDICAMENTS

Publications (2)

Publication Number Publication Date
FR2432521A1 FR2432521A1 (en) 1980-02-29
FR2432521B1 true FR2432521B1 (en) 1981-12-04

Family

ID=27446376

Family Applications (4)

Application Number Title Priority Date Filing Date
FR7809617A Granted FR2432521A1 (en) 1978-03-31 1978-03-31 NOVEL O-SUBSTITUTED OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR USE AS MEDICAMENTS
FR7824563A Granted FR2438050A2 (en) 1978-03-31 1978-08-24 NOVEL O-SUBSTITUTED OXIMES DERIVED FROM 7-AMINOTHIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
FR7901611A Granted FR2447380A2 (en) 1978-03-31 1979-01-23 NOVEL O-SUBSTITUTED OXIMES DERIVED FROM 7-AMINOTHIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
FR8001300A Granted FR2474034A2 (en) 1978-03-31 1980-01-22 NOVEL 0-SUBSTITUTED OXIMES DERIVED FROM 7-AMINOTHIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, PROCESS FOR PREPARING THEM AND THEIR APPLICATION AS MEDICAMENTS

Family Applications After (3)

Application Number Title Priority Date Filing Date
FR7824563A Granted FR2438050A2 (en) 1978-03-31 1978-08-24 NOVEL O-SUBSTITUTED OXIMES DERIVED FROM 7-AMINOTHIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
FR7901611A Granted FR2447380A2 (en) 1978-03-31 1979-01-23 NOVEL O-SUBSTITUTED OXIMES DERIVED FROM 7-AMINOTHIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
FR8001300A Granted FR2474034A2 (en) 1978-03-31 1980-01-22 NOVEL 0-SUBSTITUTED OXIMES DERIVED FROM 7-AMINOTHIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, PROCESS FOR PREPARING THEM AND THEIR APPLICATION AS MEDICAMENTS

Country Status (9)

Country Link
JP (1) JPS54132593A (en)
AT (1) AT367423B (en)
AU (1) AU526990B2 (en)
BE (1) BE875217A (en)
DE (1) DE2912829A1 (en)
FR (4) FR2432521A1 (en)
GB (2) GB2017702B (en)
LU (1) LU81104A1 (en)
NL (1) NL7902555A (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE878514A (en) * 1978-09-04 1980-02-29 Fujisawa Pharmaceutical Co PROCESS FOR THE PREPARATION OF 3-CEPHEM-4-CARBOXYLIC ACID COMPOUNDS WITH DISUBSTITUTION IN POSITIONS 3 AND 7, NOVEL PRODUCTS THUS OBTAINED AND THEIR USE FOR THEIR ANTIBACTERIAL ACTIVITY
US4409217A (en) 1977-03-14 1983-10-11 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
DE2967356D1 (en) * 1978-07-17 1985-02-28 Fujisawa Pharmaceutical Co Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them
US4284631A (en) * 1978-07-31 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them
BE878637A (en) * 1978-09-11 1980-03-06 Fujisawa Pharmaceutical Co PROCESS FOR THE PREPARATION OF 3,7-DISUBSTITUTED 3-CEPHEM-4-CARBOXYLIC ACID COMPOUNDS AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, NOVEL PRODUCTS THUS OBTAINED AND THEIR USE FOR THEIR ANTIMICROBIAL ACTIVITIES
DE2945248A1 (en) * 1978-11-13 1980-05-22 Fujisawa Pharmaceutical Co CEPHEM COMPOUNDS, METHOD FOR THEIR PRODUCTION AND ANTIBACTERIAL PHARMACEUTICAL AGENTS CONTAINING THE SAME
JPS5585594A (en) * 1978-11-13 1980-06-27 Fujisawa Pharmaceut Co Ltd Cephem compound and their preparation
ZA806977B (en) * 1979-11-19 1981-10-28 Fujisawa Pharmaceutical Co 7-acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
IL61458A0 (en) * 1979-12-07 1980-12-31 Erba Farmitalia N-substituted thiazolyl derivatives of oximino-substituted cephalosporins, their preparation and pharmalceutical compositions containing them
US4252802A (en) * 1980-03-13 1981-02-24 E. R. Squibb & Sons, Inc. Hydroxamic acid derivatives of 7-[(2-amino-4-thiazolyl)-oximino] cephalosporins
JPS5849382A (en) * 1981-09-18 1983-03-23 Kyowa Hakko Kogyo Co Ltd Beta-lactam compound
PH19163A (en) * 1982-04-06 1986-01-16 Daiichi Seiyaku Co Cephalosporin derivatives
JPS59184186A (en) * 1983-04-01 1984-10-19 Meiji Seika Kaisha Ltd Novel cephem compound
GB8413152D0 (en) 1983-06-03 1984-06-27 Ici Pharma Cephalosporin derivatives
US4690921A (en) * 1983-10-11 1987-09-01 Yamanouchi Pharmaceutical Co., Ltd. Cephalosporin compounds and salts thereof
EP0148007A3 (en) * 1983-12-26 1986-04-02 Yamanouchi Pharmaceutical Co. Ltd. Cephalosporin compounds and medicaments and their production
DE3485860T2 (en) * 1983-12-29 1993-01-14 Mochida Pharm Co Ltd CEPHALOSPORINE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS.
JPS60142987A (en) * 1983-12-29 1985-07-29 Mochida Pharmaceut Co Ltd Cephalosporin derivative
EP0182633A3 (en) * 1984-11-20 1987-09-02 Ici Pharma Cephalosporin derivatives
US4840945A (en) * 1985-04-01 1989-06-20 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
GB8519606D0 (en) * 1985-08-05 1985-09-11 Fujisawa Pharmaceutical Co 3 7-d substituted-3-cephem compounds
IL83993A0 (en) * 1986-09-26 1988-02-29 Glaxo Group Ltd Cephalosporins,their preparation and pharmaceutical compositions containing them
GB8623211D0 (en) * 1986-09-26 1986-10-29 Glaxo Group Ltd Chemical compounds
US4880798A (en) * 1986-11-25 1989-11-14 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
JPS63132893A (en) * 1986-11-25 1988-06-04 Mochida Pharmaceut Co Ltd Novel cephalosporin derivative, production thereof and antibacterial agent containing said derivative as active ingredient
US5223496A (en) * 1987-11-10 1993-06-29 The Upjohn Company Cephalosporin antibiotics
EP0393066B1 (en) * 1987-11-10 1994-02-02 The Upjohn Company Cephalosporin antibiotics
DE3911322A1 (en) * 1989-04-07 1990-10-11 Hoechst Ag METHOD FOR PRODUCING CEFODIZIM DINATRIUM

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds
SE440655B (en) * 1976-01-23 1985-08-12 Roussel Uclaf SET TO MAKE NEW OXIME DERIVATIVES OF 7-AMINO-THIAZOLYL-ACETAMIDO-CEPHALOSPORANIC ACID
GB1576625A (en) * 1976-04-12 1980-10-08 Fujisawa Pharmaceutical Co Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof
DK162391C (en) * 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co ANALOGY PROCEDURE FOR PREPARING SYN-ISOMERS OF 3,7-DISUBSTITUTED 3-CEPHEM-4-CARBOXYLIC ACID COMPOUNDS
GB1592149A (en) * 1976-10-08 1981-07-01 Fujisawa Pharmaceutical Co 3 7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for preparation thereof
JPS5387391A (en) * 1976-11-30 1978-08-01 Glaxo Lab Ltd Cephalospoline systmem compounds and process for preparing same
JPS53101393A (en) * 1977-02-17 1978-09-04 Takeda Chem Ind Ltd Cephalosporin derivatives and process for their preparation
PH17188A (en) * 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use
FR2384779A1 (en) * 1977-03-25 1978-10-20 Roussel Uclaf NEW OXIMES DERIVED FROM 3-CHLORO OR 3-METHOXY 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS
SE439312B (en) * 1977-03-25 1985-06-10 Roussel Uclaf SET TO MAKE NEW OXIME DERIVATIVES OF 3-ACETOXIMETHYL-7-AMINOTIAZOLYLACETAMIDO CEPHALOSPORANIC ACID
DE2716677C2 (en) * 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephem derivatives and processes for their preparation
DE2714880A1 (en) * 1977-04-02 1978-10-26 Hoechst Ag CEPHEMDER DERIVATIVES AND PROCESS FOR THEIR PRODUCTION
GB1599232A (en) * 1977-06-03 1981-09-30 Hoffmann La Roche 7-(2-oximinoacetamido)-cephalosporin derivatives
JPS609719B2 (en) * 1977-08-06 1985-03-12 武田薬品工業株式会社 Cephalosporin derivatives and their production method
US4284631A (en) * 1978-07-31 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them
US4313945A (en) * 1978-11-23 1982-02-02 Ciba-Geigy Corporation 7-Thiazolyl-acetamido-cephem derivatives with terminal aminocarboxylic acid grouping

Also Published As

Publication number Publication date
GB2017702A (en) 1979-10-10
BE875217A (en) 1979-10-01
FR2447380B2 (en) 1981-10-09
FR2438050A2 (en) 1980-04-30
JPS54132593A (en) 1979-10-15
FR2432521A1 (en) 1980-02-29
AU4566679A (en) 1979-10-18
NL7902555A (en) 1979-10-02
DE2912829A1 (en) 1979-10-04
GB2101117A (en) 1983-01-12
FR2438050B2 (en) 1983-04-15
LU81104A1 (en) 1979-10-30
AU526990B2 (en) 1983-02-10
GB2101117B (en) 1983-06-02
FR2474034B2 (en) 1982-01-29
FR2474034A2 (en) 1981-07-24
ATA240379A (en) 1981-11-15
AT367423B (en) 1982-07-12
JPH0314039B2 (en) 1991-02-25
FR2447380A2 (en) 1980-08-22
GB2017702B (en) 1983-02-02

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