FR2424895A1 - Nouveaux analogues de prostaglandines et medicament les contenant - Google Patents

Nouveaux analogues de prostaglandines et medicament les contenant

Info

Publication number
FR2424895A1
FR2424895A1 FR7907064A FR7907064A FR2424895A1 FR 2424895 A1 FR2424895 A1 FR 2424895A1 FR 7907064 A FR7907064 A FR 7907064A FR 7907064 A FR7907064 A FR 7907064A FR 2424895 A1 FR2424895 A1 FR 2424895A1
Authority
FR
France
Prior art keywords
products containing
prostaglandin analogues
medicinal products
new prostaglandin
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7907064A
Other languages
English (en)
Other versions
FR2424895B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of FR2424895A1 publication Critical patent/FR2424895A1/fr
Application granted granted Critical
Publication of FR2424895B1 publication Critical patent/FR2424895B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'INVENTION A TRAIT AU DOMAINE DE LA CHIMIE MEDICALE. ELLE CONCERNE DE NOUVEAUX ANALOGUES DE PROSTAGLANDINES DONT LE GROUPE CARBOXYLE EN POSITION C-2 EST REMPLACE PAR UN GROUPE ALKYLCARBONYLE, C'EST-A-DIRE UNE C-2-CETONE. LES NOUVEAUX COMPOSES DU TYPE 2-DECARBOXY-2-ALKYLCARBONYL-PG SONT DES AGENTS CYTOPROTECTEURS DU TRACTUS GASTRO-INTESTINAL; ILS SONT DEPOURVUS OU SENSIBLEMENT DEPOURVUS D'AUTRES EFFETS DU TYPE EXERCE PAR LES PROSTAGLANDINES (PAR EXEMPLE SUR LE MUSCLE LISSE ET LE SYSTEME CARDIOVASCULAIRE).
FR7907064A 1978-03-21 1979-03-20 Nouveaux analogues de prostaglandines et medicament les contenant Granted FR2424895A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/888,695 US4123463A (en) 1978-03-21 1978-03-21 2-Decarboxy-2-alkylketone prostaglandins

Publications (2)

Publication Number Publication Date
FR2424895A1 true FR2424895A1 (fr) 1979-11-30
FR2424895B1 FR2424895B1 (fr) 1981-02-13

Family

ID=25393692

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7907064A Granted FR2424895A1 (fr) 1978-03-21 1979-03-20 Nouveaux analogues de prostaglandines et medicament les contenant

Country Status (13)

Country Link
US (12) US4123463A (fr)
JP (1) JPS54141751A (fr)
AU (1) AU522799B2 (fr)
BE (1) BE874993A (fr)
CH (1) CH638480A5 (fr)
DE (1) DE2910474A1 (fr)
FR (1) FR2424895A1 (fr)
GB (1) GB2017086B (fr)
IL (1) IL56814A (fr)
IT (1) IT1209122B (fr)
NL (1) NL7902170A (fr)
SE (1) SE7902456L (fr)
ZA (1) ZA79962B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS595154A (ja) * 1982-06-30 1984-01-12 Ono Pharmaceut Co Ltd プロスタグランジンｄ類似化合物
DE3405181A1 (de) * 1984-02-10 1985-08-22 Schering AG, 1000 Berlin und 4709 Bergkamen Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US4778904A (en) * 1985-09-13 1988-10-18 Syntex (U.S.A.) Inc. Intermediates for making 16-phenoxy- and 16-(substituted phenoxy)-prostatrienoic acid derivatives
US4929740A (en) * 1984-10-09 1990-05-29 Syntex (U.S.A.) Inc. Process for making 16-phenoxy- and 16-(substituted phenoxy)-prostatrienoic acid derivatives
US5985186A (en) * 1998-02-19 1999-11-16 Gas Research Institute Method of preparing tubular ceramic articles
US20160297104A1 (en) * 2013-11-19 2016-10-13 Guill Tool & Engineering Coextruded, multilayer and multicomponent 3d printing inputs field

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2288517A1 (fr) * 1974-10-22 1976-05-21 Ono Pharmaceutical Co Prostaglandines

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3931296A (en) * 1972-12-29 1976-01-06 Masaki Hayashi Trans-Δ2 -prostaglandins
US3953435A (en) * 1974-01-10 1976-04-27 Ono Pharmaceutical Company Aldehyde derivatives of prostaglandins
GB1484591A (en) * 1974-04-11 1977-09-01 Ono Pharmaceutical Co Prostaglandin compositions
GB1482010A (en) * 1974-10-28 1977-08-03 Ono Pharmaceutical Co Prostaglandin analogues
US4032561A (en) * 1975-05-27 1977-06-28 The Upjohn Company 17-Phenyl-18,19,20-trinor-cis-4,5-didehydro-PGF1.sub.α compounds

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2288517A1 (fr) * 1974-10-22 1976-05-21 Ono Pharmaceutical Co Prostaglandines

Also Published As

Publication number Publication date
IL56814A (en) 1984-11-30
US4123463A (en) 1978-10-31
JPS6210226B2 (fr) 1987-03-05
JPS54141751A (en) 1979-11-05
US4148828A (en) 1979-04-10
US4141918A (en) 1979-02-27
GB2017086A (en) 1979-10-03
US4146561A (en) 1979-03-27
IT7921122A0 (it) 1979-03-19
US4148827A (en) 1979-04-10
FR2424895B1 (fr) 1981-02-13
NL7902170A (nl) 1979-09-25
US4144274A (en) 1979-03-13
BE874993A (fr) 1979-09-21
AU4477879A (en) 1979-09-27
DE2910474A1 (de) 1979-10-04
US4151206A (en) 1979-04-24
IT1209122B (it) 1989-07-10
US4144273A (en) 1979-03-13
CH638480A5 (de) 1983-09-30
US4148825A (en) 1979-04-10
IL56814A0 (en) 1979-05-31
GB2017086B (en) 1982-08-11
SE7902456L (sv) 1979-09-22
US4150056A (en) 1979-04-17
ZA79962B (en) 1980-03-26
DE2910474C2 (fr) 1987-05-27
US4145365A (en) 1979-03-20
AU522799B2 (en) 1982-06-24
US4154764A (en) 1979-05-15

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Legal Events

Date Code Title Description
ST Notification of lapse