FR2424275A1 - 4-Hydroxy-3-alkyl-pyridyl-thiazolidine-2-thione derivs. - are antiulcer cpds. prepd. from alpha-halo-ketone and N-pyridyl-di:thiocarbamate - Google Patents
4-Hydroxy-3-alkyl-pyridyl-thiazolidine-2-thione derivs. - are antiulcer cpds. prepd. from alpha-halo-ketone and N-pyridyl-di:thiocarbamateInfo
- Publication number
- FR2424275A1 FR2424275A1 FR7812187A FR7812187A FR2424275A1 FR 2424275 A1 FR2424275 A1 FR 2424275A1 FR 7812187 A FR7812187 A FR 7812187A FR 7812187 A FR7812187 A FR 7812187A FR 2424275 A1 FR2424275 A1 FR 2424275A1
- Authority
- FR
- France
- Prior art keywords
- pyridyl
- cpds
- alkyl
- thiazolidine
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
Abstract
4-Hydroxy-3-pyridyl-thiazolidine-2-thiones of formula (I) are new: In the formulae, R1 is opt. branched, 1-4C alkyl in position 4,5, or 6 and R2 is H or opt. branched 1-4C alkyl. The cpds. may be administered orally, rectally or parenterally e.g. orally to adults in daily doses of 50-1000 mg. Typical cpds. are (I) where R1 = 6-methyl. Cpds. where R2 = H or 1-4C primary or secondary alkyl have predominantly structure (A) whilst R2 = t-butyl has predominantly structure (B).
Priority Applications (22)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7812187A FR2424275A1 (en) | 1978-04-25 | 1978-04-25 | 4-Hydroxy-3-alkyl-pyridyl-thiazolidine-2-thione derivs. - are antiulcer cpds. prepd. from alpha-halo-ketone and N-pyridyl-di:thiocarbamate |
NL7804971A NL7804971A (en) | 1977-05-17 | 1978-05-09 | NEW 4-HYDROXYTHIAZOLIDINETHION-2 DERIVATIVES, ITS PREPARATIONS AND PREPARATIONS CONTAINING THE NEW DERIVATIVES. |
NL7804977A NL7804977A (en) | 1977-05-17 | 1978-05-09 | NEW 4-HYDROXYTHIAZOLIDINETHION-2 DERIVATIVES, ITS PREPARATIONS AND PREPARATIONS CONTAINING THE NEW DERIVATIVES. |
GR56236A GR63587B (en) | 1977-05-17 | 1978-05-15 | Method for preparation of new derivations of hydroxy-4-thiazolidinethione-2 |
ES469896A ES469896A1 (en) | 1977-05-17 | 1978-05-16 | Hydroxythiazolidine-2-thiones |
JP5816578A JPS5416476A (en) | 1977-05-17 | 1978-05-16 | 44hydroxythiazolidinee22 thione |
IE982/78A IE46828B1 (en) | 1977-05-17 | 1978-05-16 | 4-hydroxythiazolidine-2-thiones |
IT23470/78A IT1096218B (en) | 1977-05-17 | 1978-05-16 | DERIVATIVES OF HYDROXY-4 THIAZOLIDINTION-2, THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM |
GB19927/78A GB1575274A (en) | 1977-05-17 | 1978-05-16 | 4-hydroxythiazolidine-2-thiones |
BE187745A BE867129A (en) | 1977-05-17 | 1978-05-16 | NEW DERIVATIVES OF HYDROXY-4 THIAZOLIDINETHIONE-2, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM |
LU79662A LU79662A1 (en) | 1977-05-17 | 1978-05-16 | NEW DERIVATIVES OF HYDROXY-4 THIAZOLIDINE THIONE-2, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM |
US05/906,599 US4164579A (en) | 1977-05-17 | 1978-05-16 | Hydroxythiazolidine-2-thiones |
NO78781712A NO781712L (en) | 1977-05-17 | 1978-05-16 | PROCEDURE FOR PREPARING NEW DERIVATIVES OF 4-HYDROXYTIAZOLIDIN-2-THION |
IL54736A IL54736A (en) | 1977-05-17 | 1978-05-16 | 3-(substituted pyridinyl)-4-hydroxythiazolidine-2-thione derivatives, a process for their preparation and pharmaceutical compositions containing them |
AU36138/78A AU514150B2 (en) | 1977-05-17 | 1978-05-16 | 4-hydroxythiazolidine-2 thiones |
SE7805588A SE7805588L (en) | 1977-05-17 | 1978-05-16 | PROCEDURE FOR THE PREPARATION OF NEW 4-HYDROXITIAZOLIDIN-2-THION DERIVATIVES |
NZ187289A NZ187289A (en) | 1977-05-17 | 1978-05-16 | 4-hydroxy-3-(pyrid-2-yl)-thiazolidine-2-thione derivatives and pharmaceutical compositions |
PT68048A PT68048B (en) | 1977-05-17 | 1978-05-16 | NOVEL HYDROXY-THIAZOLIDINE THIONE-2 DERIVATIVES AND THE COMPOSITIONS CONTAINING THEM |
CA303,572A CA1092120A (en) | 1977-05-17 | 1978-05-17 | Pas de traduction disponible |
FI781567A FI781567A (en) | 1977-05-17 | 1978-05-17 | NYA 4-HYDROXY-THIAZOLIDINE-2-THIONER FOR FAR OVERFLOWING |
DE19782821566 DE2821566A1 (en) | 1977-05-17 | 1978-05-17 | 4-HYDROXY-THIAZOLIDINE-2-THIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS OF THESE |
PH21171A PH14032A (en) | 1978-04-25 | 1978-05-22 | 4-hydroxythiazolidine-2-thiones and compositions containing same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7812187A FR2424275A1 (en) | 1978-04-25 | 1978-04-25 | 4-Hydroxy-3-alkyl-pyridyl-thiazolidine-2-thione derivs. - are antiulcer cpds. prepd. from alpha-halo-ketone and N-pyridyl-di:thiocarbamate |
Publications (1)
Publication Number | Publication Date |
---|---|
FR2424275A1 true FR2424275A1 (en) | 1979-11-23 |
Family
ID=9207550
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7812187A Withdrawn FR2424275A1 (en) | 1977-05-17 | 1978-04-25 | 4-Hydroxy-3-alkyl-pyridyl-thiazolidine-2-thione derivs. - are antiulcer cpds. prepd. from alpha-halo-ketone and N-pyridyl-di:thiocarbamate |
Country Status (2)
Country | Link |
---|---|
FR (1) | FR2424275A1 (en) |
PH (1) | PH14032A (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3725422A (en) * | 1971-09-07 | 1973-04-03 | Parke Davis & Co | New organic sulfur compounds and methods for their production |
US3761485A (en) * | 1971-09-07 | 1973-09-25 | Parke Davis & Co | 3-(5-chloro-2-pyridyl)rhodanine and 3-(5-chloro-2-pyridyl)-5-(lower alkyl)rhodanines |
FR2381212A1 (en) * | 1977-02-22 | 1978-09-15 | Honda Motor Co Ltd | HYDRAULIC SHOCK ABSORBER FOR VEHICLES |
-
1978
- 1978-04-25 FR FR7812187A patent/FR2424275A1/en not_active Withdrawn
- 1978-05-22 PH PH21171A patent/PH14032A/en unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3725422A (en) * | 1971-09-07 | 1973-04-03 | Parke Davis & Co | New organic sulfur compounds and methods for their production |
US3761485A (en) * | 1971-09-07 | 1973-09-25 | Parke Davis & Co | 3-(5-chloro-2-pyridyl)rhodanine and 3-(5-chloro-2-pyridyl)-5-(lower alkyl)rhodanines |
FR2381212A1 (en) * | 1977-02-22 | 1978-09-15 | Honda Motor Co Ltd | HYDRAULIC SHOCK ABSORBER FOR VEHICLES |
Also Published As
Publication number | Publication date |
---|---|
PH14032A (en) | 1980-12-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |