FR2420545A1 - Nouveaux esters de l'acide n-acetyl-muramyl-aminoacyl-glutamique ou des derives de substitution de celui-ci a proprietes anti-infectieuses et/ou d'adjuvants immunologiques - Google Patents

Nouveaux esters de l'acide n-acetyl-muramyl-aminoacyl-glutamique ou des derives de substitution de celui-ci a proprietes anti-infectieuses et/ou d'adjuvants immunologiques

Info

Publication number
FR2420545A1
FR2420545A1 FR7808049A FR7808049A FR2420545A1 FR 2420545 A1 FR2420545 A1 FR 2420545A1 FR 7808049 A FR7808049 A FR 7808049A FR 7808049 A FR7808049 A FR 7808049A FR 2420545 A1 FR2420545 A1 FR 2420545A1
Authority
FR
France
Prior art keywords
muramyl
aminoacyl
acetyl
glutamic acid
new esters
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7808049A
Other languages
English (en)
French (fr)
Other versions
FR2420545B1 (enrdf_load_stackoverflow
Inventor
Pierre Lefrancier
Monique Parant
Francoise Audibert
Louis Chedid
Jean Choay
Edgar Lederer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bpifrance Financement SA
Original Assignee
Agence National de Valorisation de la Recherche ANVAR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agence National de Valorisation de la Recherche ANVAR filed Critical Agence National de Valorisation de la Recherche ANVAR
Priority to FR7808049A priority Critical patent/FR2420545A1/fr
Priority to FR7833126A priority patent/FR2442241A2/fr
Priority to PCT/FR1979/000027 priority patent/WO1979000802A1/fr
Priority to EP79400183A priority patent/EP0004512B1/fr
Priority to ES79478803A priority patent/ES478803A1/es
Priority to JP50056079A priority patent/JPS55500167A/ja
Priority to DE7979400183T priority patent/DE2966538D1/de
Priority to IE62579A priority patent/IE48735B1/en
Publication of FR2420545A1 publication Critical patent/FR2420545A1/fr
Application granted granted Critical
Publication of FR2420545B1 publication Critical patent/FR2420545B1/fr
Priority to US06/259,450 priority patent/US4396607A/en
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FR7808049A 1978-03-20 1978-03-20 Nouveaux esters de l'acide n-acetyl-muramyl-aminoacyl-glutamique ou des derives de substitution de celui-ci a proprietes anti-infectieuses et/ou d'adjuvants immunologiques Granted FR2420545A1 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
FR7808049A FR2420545A1 (fr) 1978-03-20 1978-03-20 Nouveaux esters de l'acide n-acetyl-muramyl-aminoacyl-glutamique ou des derives de substitution de celui-ci a proprietes anti-infectieuses et/ou d'adjuvants immunologiques
FR7833126A FR2442241A2 (fr) 1978-03-20 1978-11-23 Nouveaux composes esters de muramyl-peptide, leur preparation et les compositions pharmaceutiques les contenant, notamment sous forme de liposomes
EP79400183A EP0004512B1 (fr) 1978-03-20 1979-03-20 Composés esters de muramyl-peptide et leurs applications dans les compositions pharmaceutiques et réactifs de laboratoire
ES79478803A ES478803A1 (es) 1978-03-20 1979-03-20 Un procedimiento para la preparacion de derivados de acila- dos de muramil peptidos.
PCT/FR1979/000027 WO1979000802A1 (fr) 1978-03-20 1979-03-20 Nouveaux composes esters de muramyl-peptide et leurs applications dans les compositions pharmaceutiques et reactifs de laboratoire
JP50056079A JPS55500167A (enrdf_load_stackoverflow) 1978-03-20 1979-03-20
DE7979400183T DE2966538D1 (en) 1978-03-20 1979-03-20 Muramyl-peptide ester derivatives and their application to pharmacological compositions and laboratory reactants
IE62579A IE48735B1 (en) 1978-03-20 1979-08-08 Muramyl-peptide ester compounds and their application in pharmaceutical compositions and laboratory reagents
US06/259,450 US4396607A (en) 1978-03-20 1981-05-01 Muramyl peptide derivatives and pharmaceutical compositions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7808049A FR2420545A1 (fr) 1978-03-20 1978-03-20 Nouveaux esters de l'acide n-acetyl-muramyl-aminoacyl-glutamique ou des derives de substitution de celui-ci a proprietes anti-infectieuses et/ou d'adjuvants immunologiques

Publications (2)

Publication Number Publication Date
FR2420545A1 true FR2420545A1 (fr) 1979-10-19
FR2420545B1 FR2420545B1 (enrdf_load_stackoverflow) 1981-03-27

Family

ID=9206038

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7808049A Granted FR2420545A1 (fr) 1978-03-20 1978-03-20 Nouveaux esters de l'acide n-acetyl-muramyl-aminoacyl-glutamique ou des derives de substitution de celui-ci a proprietes anti-infectieuses et/ou d'adjuvants immunologiques

Country Status (3)

Country Link
JP (1) JPS55500167A (enrdf_load_stackoverflow)
FR (1) FR2420545A1 (enrdf_load_stackoverflow)
WO (1) WO1979000802A1 (enrdf_load_stackoverflow)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0135788A1 (en) * 1983-08-18 1985-04-03 Hamaoka, Toshiyuki Muramyldipeptide active ester derivatives

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62270531A (ja) * 1985-11-01 1987-11-24 サントル　ナシヨナ−ル　ド　ラ　ルシエルシユ　シヤンテイフイ−ク（セ−・エン・エル・エス） 生体内でのイメ−ジング及び治療用の新規エアロゾル組成物
ZA200502613B (en) 2002-10-10 2006-10-25 Yeda Res & Dev Basic esters of fatty alcohols and their use as anti-inflammatory or immunomodulatory agents
US9969283B2 (en) 2013-09-10 2018-05-15 General Electric Company Battery changing system and method

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2710454A1 (de) * 1976-03-10 1977-09-22 Anvar Antiinfektioese methylester, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
FR2361902A1 (fr) * 1975-12-10 1978-03-17 Ciba Geigy Ag Derives de la glucosamine et leur procede de fabrication

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1564500A (en) * 1975-09-29 1980-04-10 Wellcome Found Biological preparations
JPS52139018A (en) * 1976-03-10 1977-11-19 Anvar Immuno adjuvant and antiinfection adjuvant composed of mainly nnacetyll muramiccllalanyllddglutamic ester or nnacetyllmuramiccllalanylldd isoglutamic ester
GB1571133A (en) * 1976-04-26 1980-07-09 Syntex Inc Immuniological adjuvant peptidoglycans compounds and methods of preparation thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2361902A1 (fr) * 1975-12-10 1978-03-17 Ciba Geigy Ag Derives de la glucosamine et leur procede de fabrication
DE2710454A1 (de) * 1976-03-10 1977-09-22 Anvar Antiinfektioese methylester, verfahren zu ihrer herstellung und sie enthaltende arzneimittel

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0135788A1 (en) * 1983-08-18 1985-04-03 Hamaoka, Toshiyuki Muramyldipeptide active ester derivatives

Also Published As

Publication number Publication date
WO1979000802A1 (fr) 1979-10-18
FR2420545B1 (enrdf_load_stackoverflow) 1981-03-27
JPS55500167A (enrdf_load_stackoverflow) 1980-03-27

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