FR2419265A1 - Procede de preparation d'un acide gras marque destine a servir de produit radiopharmaceutique - Google Patents
Procede de preparation d'un acide gras marque destine a servir de produit radiopharmaceutiqueInfo
- Publication number
- FR2419265A1 FR2419265A1 FR7905992A FR7905992A FR2419265A1 FR 2419265 A1 FR2419265 A1 FR 2419265A1 FR 7905992 A FR7905992 A FR 7905992A FR 7905992 A FR7905992 A FR 7905992A FR 2419265 A1 FR2419265 A1 FR 2419265A1
- Authority
- FR
- France
- Prior art keywords
- fatty acid
- mixture
- preparation
- labeled
- radiopharmaceutical product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/15—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing halogen
- C07C53/19—Acids containing three or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0402—Organic compounds carboxylic acid carriers, fatty acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0404—Lipids, e.g. triglycerides; Polycationic carriers
- A61K51/0406—Amines, polyamines, e.g. spermine, spermidine, amino acids, (bis)guanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
a. Procédé de préparation d'un acide gras marqué destiné à servir de produit radiopharmaceutique. b. Le procédé consiste à envoyer un mélange comprenant l'acide gras inaltéré, l'acide gras marqué par l'iode 123 en position oméga, une cétone et un iodure, en vue de séparer cbromatographiquement l'acide gras marqué par l'iode 123 en position oméga des autres constituants du mélange, sur une colonne de séparation garnie d'une substance de garnissage ayant une granulométrie déterminée comprise entre 5 et 30 mu , le mélange étant entraîné par un véhicule liquide envoyé sous pression dans la colonne de séparation c. Utilisation en médecine.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2810696A DE2810696C3 (de) | 1978-03-11 | 1978-03-11 | Verfahren zur Gewinnung von ω-↑123↑J-Hexadecansäure oder ω↑123↑J-Heptadecansäure und deren Verwendung als Radiopharmaka |
Publications (1)
Publication Number | Publication Date |
---|---|
FR2419265A1 true FR2419265A1 (fr) | 1979-10-05 |
Family
ID=6034214
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7905992A Withdrawn FR2419265A1 (fr) | 1978-03-11 | 1979-03-08 | Procede de preparation d'un acide gras marque destine a servir de produit radiopharmaceutique |
Country Status (5)
Country | Link |
---|---|
DE (1) | DE2810696C3 (fr) |
FR (1) | FR2419265A1 (fr) |
GB (1) | GB2016455A (fr) |
NL (1) | NL7901820A (fr) |
SE (1) | SE7901916L (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2508902A1 (fr) * | 1981-07-02 | 1983-01-07 | Commissariat Energie Atomique | Procede de preparation extemporanee d'un acide gras injectable, marque a l'iode radioactif et preparation de derives iodes utilisables pour la mise en oeuvre de ce procede |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1236483A (fr) * | 1984-03-19 | 1988-05-10 | Commonwealth Of Australia (The) | Marquage des molecules organiques |
-
1978
- 1978-03-11 DE DE2810696A patent/DE2810696C3/de not_active Expired
-
1979
- 1979-03-02 SE SE7901916A patent/SE7901916L/xx unknown
- 1979-03-07 NL NL7901820A patent/NL7901820A/xx not_active Application Discontinuation
- 1979-03-08 FR FR7905992A patent/FR2419265A1/fr not_active Withdrawn
- 1979-03-12 GB GB7908612A patent/GB2016455A/en not_active Withdrawn
Non-Patent Citations (3)
Title |
---|
EXBK/76 * |
EXBK/77 * |
EXBK/78 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2508902A1 (fr) * | 1981-07-02 | 1983-01-07 | Commissariat Energie Atomique | Procede de preparation extemporanee d'un acide gras injectable, marque a l'iode radioactif et preparation de derives iodes utilisables pour la mise en oeuvre de ce procede |
EP0069648A1 (fr) * | 1981-07-02 | 1983-01-12 | Commissariat à l'Energie Atomique | Procédé de préparation extemporanée d'un acide gras injectable, marqué à l'iode radioactif et préparation de dérivés iodes utilisables pour la mise en oeuvre de ce procédé |
US4476106A (en) * | 1981-07-02 | 1984-10-09 | Commissariat A L'energie Atomique | Process for the extemporaneous preparation of an injectable fatty acid tagged in the omega position by means of radioactive iodine |
Also Published As
Publication number | Publication date |
---|---|
DE2810696A1 (de) | 1979-09-13 |
DE2810696B2 (de) | 1981-01-08 |
NL7901820A (nl) | 1979-09-13 |
SE7901916L (sv) | 1979-09-12 |
DE2810696C3 (de) | 1982-02-25 |
GB2016455A (en) | 1979-09-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |