FR2418795A1 - Facteurs de fortimycine kg1, kg2 et kg3 et procedes pour leur production - Google Patents

Facteurs de fortimycine kg1, kg2 et kg3 et procedes pour leur production

Info

Publication number
FR2418795A1
FR2418795A1 FR7905359A FR7905359A FR2418795A1 FR 2418795 A1 FR2418795 A1 FR 2418795A1 FR 7905359 A FR7905359 A FR 7905359A FR 7905359 A FR7905359 A FR 7905359A FR 2418795 A1 FR2418795 A1 FR 2418795A1
Authority
FR
France
Prior art keywords
fortimycin
factors
production
methods
represented
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7905359A
Other languages
English (en)
French (fr)
Other versions
FR2418795B1 (cg-RX-API-DMAC7.html
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Publication of FR2418795A1 publication Critical patent/FR2418795A1/fr
Application granted granted Critical
Publication of FR2418795B1 publication Critical patent/FR2418795B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/46—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin
    • C12P19/48—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin the cyclohexyl radical being substituted by two or more nitrogen atoms, e.g. destomycin, neamin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/29—Micromonospora
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/867—Micromonospora

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)
FR7905359A 1978-03-03 1979-03-01 Facteurs de fortimycine kg1, kg2 et kg3 et procedes pour leur production Granted FR2418795A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP53023552A JPS6041679B2 (ja) 1978-03-03 1978-03-03 新抗生物質ホ−テイマイシンｋｇ↓１，ｋｇ↓２およびｋｇ↓３ならびにそれらの製造法

Publications (2)

Publication Number Publication Date
FR2418795A1 true FR2418795A1 (fr) 1979-09-28
FR2418795B1 FR2418795B1 (cg-RX-API-DMAC7.html) 1982-03-19

Family

ID=12113645

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7905359A Granted FR2418795A1 (fr) 1978-03-03 1979-03-01 Facteurs de fortimycine kg1, kg2 et kg3 et procedes pour leur production

Country Status (6)

Country Link
US (2) US4241182A (cg-RX-API-DMAC7.html)
JP (1) JPS6041679B2 (cg-RX-API-DMAC7.html)
CA (1) CA1129796A (cg-RX-API-DMAC7.html)
DE (1) DE2908150C2 (cg-RX-API-DMAC7.html)
FR (1) FR2418795A1 (cg-RX-API-DMAC7.html)
GB (1) GB2018246B (cg-RX-API-DMAC7.html)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4338307A (en) * 1980-11-10 1982-07-06 Abbott Laboratories 2'-N-Des-β-lysyl antibiotic AX-127B-1 and 4-N-acyl and alkyl derivatives thereof
US4338309A (en) * 1980-11-10 1982-07-06 Abbott Laboratories 4',5'-Dihydro-antibiotic AX-127B-1; 2'-N-des-β-lysyl-4',5'-dihydro-antibiotic AX-127B-1; and 4-N-derivatives thereof
US4338308A (en) * 1980-11-10 1982-07-06 Abbott Laboratories 4-N-β-Lysyl-2'-N-des-β-lysyl antibiotic AX-127B-1 and the pharmaceutically acceptable salts thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3931400A (en) * 1973-04-17 1976-01-06 Abbott Laboratories Fortimicin B and process for production thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5145675B2 (cg-RX-API-DMAC7.html) * 1973-07-23 1976-12-04
US3991183A (en) * 1975-05-01 1976-11-09 Pfizer Inc. Antibiotic produced by a species of micromonospora
JPS5218888A (en) * 1975-08-01 1977-02-12 Kyowa Hakko Kogyo Co Ltd Preparation of fortimicin c
US4091032A (en) * 1976-09-23 1978-05-23 Abbott Laboratories 4-N-acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A
US4124756A (en) * 1976-12-27 1978-11-07 Abbott Laboratories 3-DE-O-Methylfortimicins
JPS53141244A (en) 1977-05-11 1978-12-08 Kyowa Hakko Kogyo Co Ltd Novel hortemycin derivatives
JPS5466679A (en) 1977-11-07 1979-05-29 Kyowa Hakko Kogyo Co Ltd Novel antibiotic substance fortimicin kf and fortimicin kg, and their preparation
US4187299A (en) 1977-12-21 1980-02-05 Abbott Laboratories Fortimicin E

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3931400A (en) * 1973-04-17 1976-01-06 Abbott Laboratories Fortimicin B and process for production thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/77 *

Also Published As

Publication number Publication date
DE2908150A1 (de) 1979-09-06
DE2908150C2 (de) 1982-04-01
GB2018246A (en) 1979-10-17
CA1129796A (en) 1982-08-17
US4623722A (en) 1986-11-18
JPS54117478A (en) 1979-09-12
GB2018246B (en) 1982-08-11
JPS6041679B2 (ja) 1985-09-18
FR2418795B1 (cg-RX-API-DMAC7.html) 1982-03-19
US4241182A (en) 1980-12-23

Similar Documents

Publication Publication Date Title
FR2430938A1 (fr) Nouvelles oxybenzylidenes bornanones, leur procede de preparation, et compositions cosmetiques les contenant
FR2405945A1 (fr) Nouveaux derives de l'acide 4 dithio 3-methylenebutyrique et procede pour leur preparation
FR2384753A1 (fr) Nouveaux thiols et leur procede de preparation
FR2375187A1 (fr) Cyclopentane-1-amines, procede pour leur preparation et produits contenant ces composes
FR2354324A1 (fr) Nouveaux composes triazoliques, leur procede de preparation et leurs applications au traitement de plantes
FR2365567A1 (fr) Nouvelles piperazinylpyridines utiles comme medicaments
FR2364896A1 (fr) Nouveaux derives de l'aniline utiles comme agents de lutte contre les parasites
FR2401144A1 (fr) Derives de benzimidazole contenant du soufre, procede pour leur preparation et intermediaires utiles pour leur production
FR2436150A1 (fr) Derives de 3'',4''-diacyltylosine utiles comme medicaments
FR2362114A1 (fr) Nouvelles substances a action stimulatrice sur les b-recepteurs adrenergiques, procedes pour leur preparation et leur utilisation therapeutique
FR2418795A1 (fr) Facteurs de fortimycine kg1, kg2 et kg3 et procedes pour leur production
FR2383931A1 (fr) Derives d'oxadiazolopyrimidine
FR2392958A1 (fr) Nouveaux amino-acides fluores utiles comme medicament
FR2374302A1 (fr) Nouvelles halogenethyl-sulfones, leur procede de preparation et leur application comme substances de croissance des plantes
FR2380246A1 (fr) Nouveaux esters d'acide cyclopropane carboxylique utiles comme pesticides
FR2422676A1 (fr) Complexes catalytiques de phosphorines metalliques
FR2356657A1 (fr) Nouveaux derives phospholipidiques de prostaglandines et leur procede de preparation
FR2359111A1 (fr) Nouveaux derives d'acides phenoxyphenoxy-alcanecarboxyliques utiles comme herbicides
FR2436139A1 (fr) 1-benzoyl-3-thiosemicarbazides substitues, leur obtention et leur application comme regulateurs de la croissance des plantes
FR2380247A1 (fr) Nouveaux esters de l'acide cyclopropane carboxylique utiles comme pesticides
FR2377382A1 (fr) Nouveaux phenylazacycloalcanes utiles comme medicaments
FR2359154A1 (fr) Derives peptidiques utiles comme medicaments et procede pour leur preparation
FR2385686A1 (fr) Nouveaux anilides utiles comme agents microbicides
FR2426688A1 (fr) Nouvelles neplanocines antibiotiques
FR2384771A1 (fr) Derives de quinazoline utiles comme medicament

Legal Events

Date Code Title Description
ST Notification of lapse