FR2415461A1 - Antiinflammatory, analgesic antipyretic phthalide(s) - prepd. from 2-carboxy benzaldehyde and a cpd. having an active hydrogen - Google Patents

Antiinflammatory, analgesic antipyretic phthalide(s) - prepd. from 2-carboxy benzaldehyde and a cpd. having an active hydrogen

Info

Publication number
FR2415461A1
FR2415461A1 FR7802286A FR7802286A FR2415461A1 FR 2415461 A1 FR2415461 A1 FR 2415461A1 FR 7802286 A FR7802286 A FR 7802286A FR 7802286 A FR7802286 A FR 7802286A FR 2415461 A1 FR2415461 A1 FR 2415461A1
Authority
FR
France
Prior art keywords
acyloxy
alkoxy
phthalide
prepd
cpd
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7802286A
Other languages
French (fr)
Other versions
FR2415461B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to FR7802286A priority Critical patent/FR2415461A1/en
Publication of FR2415461A1 publication Critical patent/FR2415461A1/en
Application granted granted Critical
Publication of FR2415461B1 publication Critical patent/FR2415461B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3

Abstract

Phthalide derivs. of formula (I) are new: In (I) Z is either a gp. (II) or (un)satd. alicyclic gp. which has >=1 hydroxyl, alkoxy, acyloxy and/or oxo gp. or it is a N or S contg. heterocycle having 1 hydroxyl, alkoxy, acyloxy and/or oxo gp. or it is a N or S contg. heterocycle having >=1 hydroxyl, alkoxy, acyloxy and/or oxo gp; R1-R5 are each halogen, alkyl, cycloalkyl, haloalkyl, aryl, hydroxy, alkoxy, haloalkoxy, acyloxy, alkylthio, haloalkylthio, carboxy, carboxyalkyl, alkylcarbonyl, alkoxycarbonyl, alkylaminocarbonyl, nitrile or nitro, >=1 being hydroxy alkoxy or acyloxy, and R1 and/or R2 and/or R3 and/or R4 and/or R5 may form part of an alicyclic, aromatic polycyclic or heterocyclic fused ring, which may be substd. The cpds. may be given orally, parenterally or rectally, the normal dosage being 200 mg 2-6 times daily.
FR7802286A 1978-01-27 1978-01-27 Antiinflammatory, analgesic antipyretic phthalide(s) - prepd. from 2-carboxy benzaldehyde and a cpd. having an active hydrogen Granted FR2415461A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7802286A FR2415461A1 (en) 1978-01-27 1978-01-27 Antiinflammatory, analgesic antipyretic phthalide(s) - prepd. from 2-carboxy benzaldehyde and a cpd. having an active hydrogen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7802286A FR2415461A1 (en) 1978-01-27 1978-01-27 Antiinflammatory, analgesic antipyretic phthalide(s) - prepd. from 2-carboxy benzaldehyde and a cpd. having an active hydrogen

Publications (2)

Publication Number Publication Date
FR2415461A1 true FR2415461A1 (en) 1979-08-24
FR2415461B1 FR2415461B1 (en) 1981-03-06

Family

ID=9203884

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7802286A Granted FR2415461A1 (en) 1978-01-27 1978-01-27 Antiinflammatory, analgesic antipyretic phthalide(s) - prepd. from 2-carboxy benzaldehyde and a cpd. having an active hydrogen

Country Status (1)

Country Link
FR (1) FR2415461A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0059884A1 (en) * 1981-03-11 1982-09-15 Schering Aktiengesellschaft Benzofurane derivatives, their preparation and use

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3305560A (en) * 1965-10-22 1967-02-21 Mcneilab Inc 3-phthalidyl-2-indolinones

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3305560A (en) * 1965-10-22 1967-02-21 Mcneilab Inc 3-phthalidyl-2-indolinones

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NV914/61 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0059884A1 (en) * 1981-03-11 1982-09-15 Schering Aktiengesellschaft Benzofurane derivatives, their preparation and use

Also Published As

Publication number Publication date
FR2415461B1 (en) 1981-03-06

Similar Documents

Publication Publication Date Title
MX9603506A (en) Heteroaromatic oxazole compounds and use thereof.
ATE236893T1 (en) SUBSTITUTED TETRACYCLIC TETRAHYDROFURAN DERIVATIVES
YU16001A (en) Pyrroloindoles, pyridoindoles and azepinoindoles as 5-ht2c agonists
AU2001272666A1 (en) 2-adamantylethylamines and their use in the treatment of conditions generally associated with abnormalities in glutamatergic transmission
FR2415461A1 (en) Antiinflammatory, analgesic antipyretic phthalide(s) - prepd. from 2-carboxy benzaldehyde and a cpd. having an active hydrogen
ES8703431A1 (en) Substituted 5-amino-1-phenyl pyrazoles.
HUP9901022A2 (en) Hydroxamic acid based collagenase inhibitors
DE60009263D1 (en) 2-ADAMANTANMETHANAMINE COMPOUNDS FOR TREATING DEVIATIONS IN GLUTAMATERGIC TRANSMISSIONS
NZ329954A (en) Isoxazolidine tetracyclic and tricyclic ring system derivatives and medicaments
MY103572A (en) 3,4-dihydro-2-alkyl-3-oxo-n-aryl-2h-[1] benzothieno [3,2-e]-1,2-thiazine-4-carboxamide-1, 1-dioxides.
FR2315924A1 (en) Analgesic and antiinflammatory polymethylene pyrazole derivs. - prepd. by cyclizing 2-acyl cyclic ketones with hydrazine derivs.
HUT45373A (en) Herbicides containing as active substance derivatives of 1-carbamoil-2-pinasoline and process for production of the active substances
FR2201885A1 (en) 4-Aryl carbonyl methyl pyrimidine oxime carbamates - prepd. by treatment of the oxime with an isocyanate, used as sedatives, analgesics, vasodilators, diuretics
FR2113760A1 (en) 5-Arylcarbonyl-3(or 4)-methylthien-2-yl alkanoic acids and esters - with antiinflammatory and analgesic activity
FR2244514A1 (en) 1,2-Dihydroquinoline derivs - useful as anti-inflammatories
FR2339613A1 (en) Antibacterial pyrazine (1,4)-dioxide derivs. - prepd. by reacting pyrido- or pyrimido-furoxan cpds. with oxo cpds.
ES366502A1 (en) 1-acyl-5-phenyl-1h-1,5-benzodiazephine-2,4-{8 3h,5h{9 -diones
ES8603804A1 (en) Substituted 4'-hydroxy-alpha-ethyl benzhydroles for use as medicaments.
PT64732A (en) Process for the preparation of new thiadiazolylimidazolines
JPS5242877A (en) Process for preparation of hydantoins

Legal Events

Date Code Title Description
ST Notification of lapse