FR2412549A1 - Derives de la rifamycine, procede pour leur preparation et leur application en tant que medicaments ayant une activite anti-bacterienne - Google Patents

Derives de la rifamycine, procede pour leur preparation et leur application en tant que medicaments ayant une activite anti-bacterienne

Info

Publication number
FR2412549A1
FR2412549A1 FR7835748A FR7835748A FR2412549A1 FR 2412549 A1 FR2412549 A1 FR 2412549A1 FR 7835748 A FR7835748 A FR 7835748A FR 7835748 A FR7835748 A FR 7835748A FR 2412549 A1 FR2412549 A1 FR 2412549A1
Authority
FR
France
Prior art keywords
preparation
rifamycins
application
medicinal products
bacterial activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7835748A
Other languages
English (en)
Other versions
FR2412549B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alfa Farmaceutici SpA
Original Assignee
Alfa Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Farmaceutici SpA filed Critical Alfa Farmaceutici SpA
Publication of FR2412549A1 publication Critical patent/FR2412549A1/fr
Application granted granted Critical
Publication of FR2412549B1 publication Critical patent/FR2412549B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

DES 8-AMINO- ET 8-IMINO-RIFAMYCINES S ET SV SONT PREPAREES PAR REACTION DE 8-METHOXYRIFAMYCINE S AVEC L'AMMONIAC DANS UN SOLVANT INERTE, POLAIRE ET HYDROPHILE, PAR CONVERSION DE LA 8-IMINORIFAMYCINE S EN 8-AMINORIFAMYCINE S PAR REACTION AVEC L'HYDROXYDE D'AMMONIUM DANS UN MELANGE DE CHLOROFORME ET DE METHANOL ET, SI ON LE DESIRE, PAR TRANSFORMATION DES FORMES S EN FORMES SV PAR REDUCTION. LES 8-AMINO- ET LES 8-IMINO-RIFAMYCINES S ET SV ONT UNE ACTIVITE ANTIBACTERIENNE ET DES APPLICATIONS THERAPEUTIQUES QUI SONT COMPARABLES A CELLES DES RIFAMYCINES S ET SV. ELLES SONT DONC UTILES CONTRE LES INFECTIONS PROVOQUEES PAR LES MICRO-ORGANISMES PATHOGENES TELS QUE, NOTAMMENT, LE MYCOBACTERIUM TUBERCULOSIS. EN OUTRE, CE SONT DES PRODUITS INTERMEDIAIRES INTERESSANTS POUR LA PREPARATION DE DERIVES QUI COMPORTENT D'AUTRES SUBSTITUANTS EN POSITION 8 ET POSSEDENT UNE ACTIVITE ANTIBACTERIENNE ET ANTIVIRALE.
FR7835748A 1977-12-20 1978-12-20 Derives de la rifamycine, procede pour leur preparation et leur application en tant que medicaments ayant une activite anti-bacterienne Granted FR2412549A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT03654/77A IT1090772B (it) 1977-12-20 1977-12-20 Derivati della rifamicina e procedimento per la loro preparazione

Publications (2)

Publication Number Publication Date
FR2412549A1 true FR2412549A1 (fr) 1979-07-20
FR2412549B1 FR2412549B1 (fr) 1981-08-14

Family

ID=11111152

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7835748A Granted FR2412549A1 (fr) 1977-12-20 1978-12-20 Derives de la rifamycine, procede pour leur preparation et leur application en tant que medicaments ayant une activite anti-bacterienne

Country Status (8)

Country Link
US (1) US4200574A (fr)
JP (1) JPS54117497A (fr)
BE (1) BE872783A (fr)
CH (1) CH639385A5 (fr)
FR (1) FR2412549A1 (fr)
GB (1) GB2010245B (fr)
IT (1) IT1090772B (fr)
NL (1) NL7812302A (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6861053B1 (en) * 1999-08-11 2005-03-01 Cedars-Sinai Medical Center Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth
US7048906B2 (en) 1995-05-17 2006-05-23 Cedars-Sinai Medical Center Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2311018A1 (fr) * 1975-05-15 1976-12-10 Archifar Ind Chim Trentino Nouveaux composes de rifamycine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1090115A (en) * 1964-04-02 1967-11-08 Lepetit Spa Mannich bases of rifamycin sv
FR208F (fr) * 1964-07-31

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2311018A1 (fr) * 1975-05-15 1976-12-10 Archifar Ind Chim Trentino Nouveaux composes de rifamycine

Also Published As

Publication number Publication date
IT1090772B (it) 1985-06-26
GB2010245B (en) 1982-07-28
GB2010245A (en) 1979-06-27
BE872783A (fr) 1979-03-30
CH639385A5 (it) 1983-11-15
FR2412549B1 (fr) 1981-08-14
NL7812302A (nl) 1979-06-22
US4200574A (en) 1980-04-29
JPS54117497A (en) 1979-09-12

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Legal Events

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ST Notification of lapse