FR2411191A1 - Derives d'imidazole-diazepine utiles comme intermediaires de preparation du (r)-3-(2-desoxy-ss-d-erythropentofurannosyl)-2,6,7,8, - tetrahydro - imidazol - /,5-d)(1,3) - diazepin-8-ol - Google Patents
Derives d'imidazole-diazepine utiles comme intermediaires de preparation du (r)-3-(2-desoxy-ss-d-erythropentofurannosyl)-2,6,7,8, - tetrahydro - imidazol - /,5-d)(1,3) - diazepin-8-olInfo
- Publication number
- FR2411191A1 FR2411191A1 FR7906591A FR7906591A FR2411191A1 FR 2411191 A1 FR2411191 A1 FR 2411191A1 FR 7906591 A FR7906591 A FR 7906591A FR 7906591 A FR7906591 A FR 7906591A FR 2411191 A1 FR2411191 A1 FR 2411191A1
- Authority
- FR
- France
- Prior art keywords
- preparation
- erythropentofurannosyl
- desoxy
- diazepin
- intermediaries
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/052—Imidazole radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/88—Nitrogen atoms, e.g. allantoin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
LA PRESENTE INVENTION CONCERNE DE NOUVEAUX DERIVES D'IMIDAZOLE-DIAZEPINE ET UN PROCEDE POUR LEUR PREPARATION. CES NOUVEAUX DERIVES SONT LA 6,7-DIHYDRO-IMIDAZO4,5-D1,3DIAZEPIN-8(3H)-ONE DE FORMULE: (CF DESSIN DANS BOPI) ET SES SELS D'ADDITION ACIDE. CES DERIVES SONT UTILES COMME INTERMEDIAIRES DANS LA PREPARATION DU (R)-3-(2-DESOXY-SS-D-ERYTHROPENTOFURANNOSYL)-3,6,7,8-TETRAHYDRO-IMIDAZO-4,5-D1,3-DIAZEPIN-8-OL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/841,098 US4117229A (en) | 1977-10-11 | 1977-10-11 | 2-amino-1-(5-amino-1h-imidazol-4-yl)ethanone and method of preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2411191A1 true FR2411191A1 (fr) | 1979-07-06 |
FR2411191B1 FR2411191B1 (fr) | 1982-02-12 |
Family
ID=25284009
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7823597A Granted FR2411207A1 (fr) | 1977-10-11 | 1978-08-10 | Derives d'imidazole, procedes pour leur preparation et transformation de ces derives en (r)-3-(2-desoxy-b-d-erythropentofurannosyl)-3,6,7,8-tetrahydro-imidazol-(4,5-d)-(1,3) diazepin-8-ol |
FR7906591A Granted FR2411191A1 (fr) | 1977-10-11 | 1979-03-15 | Derives d'imidazole-diazepine utiles comme intermediaires de preparation du (r)-3-(2-desoxy-ss-d-erythropentofurannosyl)-2,6,7,8, - tetrahydro - imidazol - /,5-d)(1,3) - diazepin-8-ol |
FR7906590A Granted FR2411181A1 (fr) | 1977-10-11 | 1979-03-15 | Derives d'imidazole utiles comme intermediaires de preparation du (r)-3-(2-desoxy-ss-d-erythropentofurannosyl)-3,6,7,8-tetrahydro-imidazol-(4,5-d) (1,3)-diazepin-8-ol |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7823597A Granted FR2411207A1 (fr) | 1977-10-11 | 1978-08-10 | Derives d'imidazole, procedes pour leur preparation et transformation de ces derives en (r)-3-(2-desoxy-b-d-erythropentofurannosyl)-3,6,7,8-tetrahydro-imidazol-(4,5-d)-(1,3) diazepin-8-ol |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7906590A Granted FR2411181A1 (fr) | 1977-10-11 | 1979-03-15 | Derives d'imidazole utiles comme intermediaires de preparation du (r)-3-(2-desoxy-ss-d-erythropentofurannosyl)-3,6,7,8-tetrahydro-imidazol-(4,5-d) (1,3)-diazepin-8-ol |
Country Status (11)
Country | Link |
---|---|
US (1) | US4117229A (fr) |
JP (1) | JPS5461177A (fr) |
AU (1) | AU520742B2 (fr) |
CA (1) | CA1109465A (fr) |
DE (1) | DE2835144A1 (fr) |
ES (3) | ES472478A1 (fr) |
FR (3) | FR2411207A1 (fr) |
GB (2) | GB2013680B (fr) |
IT (1) | IT1107776B (fr) |
MY (1) | MY8500742A (fr) |
NL (1) | NL7808365A (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1670809A2 (fr) * | 2003-09-15 | 2006-06-21 | SuperGen, Inc. | Synthese et production de pentostatine, precurseurs, analogues et derives de cette derniere |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3321023A1 (de) * | 1983-06-10 | 1984-12-13 | Basf Ag, 6700 Ludwigshafen | Triazolylalkohole, verfahren zu ihrer herstellung und ihre verwendung als fungizide |
JPH01250380A (ja) * | 1987-12-26 | 1989-10-05 | Tokyo Tanabe Co Ltd | 光学活性ベンゾキノリジン誘導体、その製造方法およびそれを有効成分とする抗菌剤 |
JPH09241294A (ja) * | 1996-03-07 | 1997-09-16 | Microbial Chem Res Found | 2′−デオキシ−2′−ハロコホルマイシン又はその立体異性体の製造法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3670007A (en) * | 1967-11-21 | 1972-06-13 | Salk Inst For Biological Studi | Aminomalonitrile and method of preparation thereof |
US3923785A (en) * | 1974-04-22 | 1975-12-02 | Parke Davis & Co | (R)-3-(2-deoxy-{62 -D-erythro-pentofuranosyl)-3,6,7,8-tetrahydroimidazo{8 4,5-d{9 {8 1,3{9 diazepin-8-ol |
-
1977
- 1977-10-11 US US05/841,098 patent/US4117229A/en not_active Expired - Lifetime
-
1978
- 1978-08-10 AU AU38816/78A patent/AU520742B2/en not_active Expired
- 1978-08-10 GB GB7907717A patent/GB2013680B/en not_active Expired
- 1978-08-10 NL NL7808365A patent/NL7808365A/xx not_active Application Discontinuation
- 1978-08-10 IT IT50697/78A patent/IT1107776B/it active
- 1978-08-10 ES ES472478A patent/ES472478A1/es not_active Expired
- 1978-08-10 GB GB7832981A patent/GB2005661B/en not_active Expired
- 1978-08-10 CA CA309,121A patent/CA1109465A/fr not_active Expired
- 1978-08-10 JP JP9674878A patent/JPS5461177A/ja active Pending
- 1978-08-10 DE DE19782835144 patent/DE2835144A1/de not_active Withdrawn
- 1978-08-10 FR FR7823597A patent/FR2411207A1/fr active Granted
-
1979
- 1979-03-15 FR FR7906591A patent/FR2411191A1/fr active Granted
- 1979-03-15 FR FR7906590A patent/FR2411181A1/fr active Granted
- 1979-04-16 ES ES479618A patent/ES479618A1/es not_active Expired
- 1979-04-16 ES ES479619A patent/ES8104992A1/es not_active Expired
-
1985
- 1985-12-30 MY MY742/85A patent/MY8500742A/xx unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1670809A2 (fr) * | 2003-09-15 | 2006-06-21 | SuperGen, Inc. | Synthese et production de pentostatine, precurseurs, analogues et derives de cette derniere |
EP1670809A4 (fr) * | 2003-09-15 | 2009-12-23 | Mayne Pharma Plc | Synthese et production de pentostatine, precurseurs, analogues et derives de cette derniere |
Also Published As
Publication number | Publication date |
---|---|
GB2013680A (en) | 1979-08-15 |
GB2013680B (en) | 1982-03-31 |
ES479619A0 (es) | 1981-05-16 |
JPS5461177A (en) | 1979-05-17 |
FR2411207B1 (fr) | 1982-07-02 |
FR2411181B1 (fr) | 1981-10-23 |
IT1107776B (it) | 1985-11-25 |
GB2005661B (en) | 1982-03-10 |
AU520742B2 (en) | 1982-02-25 |
IT7850697A0 (it) | 1978-08-10 |
DE2835144A1 (de) | 1979-04-12 |
CA1109465A (fr) | 1981-09-22 |
FR2411181A1 (fr) | 1979-07-06 |
NL7808365A (nl) | 1979-04-17 |
ES472478A1 (es) | 1979-10-16 |
US4117229A (en) | 1978-09-26 |
ES8104992A1 (es) | 1981-05-16 |
GB2005661A (en) | 1979-04-25 |
FR2411207A1 (fr) | 1979-07-06 |
FR2411191B1 (fr) | 1982-02-12 |
MY8500742A (en) | 1985-12-31 |
ES479618A1 (es) | 1979-08-01 |
AU3881678A (en) | 1980-02-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
RO75478A (fr) | PROCEDE POUR LA PREPARATION DES DERIVES D'ACIDE ALPROCEDE POUR LA PREPARATION DES DERIVES DE L'ACIDE ALPHA-PHENO0YPROïIONIQUE PHA-PHENOXYPROPIONIQUE | |
RO75256A (fr) | Procede pour la preparation des derives d'acide 1,2,3, thiazole-5-carboxylique | |
RO80265A (fr) | Procede pour la preparation de derives de l'acide beta-carboline-3-carboxyliqye | |
BE862618A (fr) | Procede d'obtention de mutants de l'espece penicillium ayant une aptitude amelioree a la synthese de l'acide mycophenolique | |
FR2407928A1 (fr) | Derives de quinazoline utiles comme medicaments antihypertenseurs et procede de leur preparation | |
FR2363608A1 (fr) | Procede de preparation de colorants " bisazoiques " | |
BE883909A (fr) | Procede de preparation de chloro-2proprionate d'alcoyle par chloration de lactate d'alcoyle | |
FR2411191A1 (fr) | Derives d'imidazole-diazepine utiles comme intermediaires de preparation du (r)-3-(2-desoxy-ss-d-erythropentofurannosyl)-2,6,7,8, - tetrahydro - imidazol - /,5-d)(1,3) - diazepin-8-ol | |
PT67004B (fr) | Procede pour la preparation de derives de l'acide 7-acilamine-8-oxo-3-oxa-1-azabicicle-/4,2,0/-octane-2-carboxique | |
PT67088B (fr) | Procede de preparation de derives de l'acide (phenyl-3-amino-2-propionyloxy)-2 acetique | |
FR2377367A1 (fr) | Procede de preparation d'alcoxy-cetones | |
FR2374302A1 (fr) | Nouvelles halogenethyl-sulfones, leur procede de preparation et leur application comme substances de croissance des plantes | |
FR2358401A1 (fr) | Nouveaux derives d'oxadiazine, leur procede de preparation et leur application comme insecticides | |
FR2361341A1 (fr) | Procede de preparation d'esters de l'acide anthranilique | |
TNSN90043A1 (fr) | Procede de preparation des derives sulfonyles de la thieno- - triazolo - diazepine | |
FR2383177A1 (fr) | Procede de preparation de derives de 2,1,3-thiadiazine-4-one-2,2-dioxyde | |
TNSN88070A1 (fr) | Procede de preparation de l'acide (pyridyl-3)-3-1h, 3h-pyrrolo (1,2-c) thiazolecarboxylique-7dextrogyre | |
FR2378798A1 (fr) | Procede de preparation de derives de 1 a-hydroxy-cholesterol | |
FR2429211A1 (fr) | Procede de production de derives de n-methylbenzothiazolone substitues en position 4 | |
RO80464A (fr) | Procede de preparation des derives de l'acide 2-(3-aryle)-5-isoxazole-ylbenzoique | |
FR2362808A1 (fr) | Procede de preparation de 2-alkyl-2-methylpropane-1,3-diols | |
FR2376190A1 (fr) | Procede de preparation de pigments azoiques | |
RO81174A (fr) | Procede de preparation du complexe forme entre beta-diethylaminoethylamide de l'acide p-chlor henoxyacetique avec 4-n-butyle 3,5-diceto-1,enylpyrazolidine | |
FR2348700A1 (fr) | Procede pour la preparation de derives para-substitues de l'acide alpha-phenyl-propionique,ainsi que ces derives | |
FR2396761A1 (fr) | Procede de preparation du r,s-2,3,5,6-tetrahydro-6-phenyl-imidazo (2,1-b)-thiazole et de ses sels d'addition d'acide pharmaceutiquement acceptables, mettant en oeuvre un alkylxanthogenate ou du thiophene |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |