FR2410652A2 - ANALOGUES OF 5,6-DIHYDRO-PROSTACYCLINE AND THEIR PREPARATION - Google Patents

ANALOGUES OF 5,6-DIHYDRO-PROSTACYCLINE AND THEIR PREPARATION

Info

Publication number
FR2410652A2
FR2410652A2 FR7834072A FR7834072A FR2410652A2 FR 2410652 A2 FR2410652 A2 FR 2410652A2 FR 7834072 A FR7834072 A FR 7834072A FR 7834072 A FR7834072 A FR 7834072A FR 2410652 A2 FR2410652 A2 FR 2410652A2
Authority
FR
France
Prior art keywords
prostacycline
dihydro
analogues
preparation
bopi
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7834072A
Other languages
French (fr)
Other versions
FR2410652B2 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/857,203 external-priority patent/US4125713A/en
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of FR2410652A2 publication Critical patent/FR2410652A2/en
Application granted granted Critical
Publication of FR2410652B2 publication Critical patent/FR2410652B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Epoxy Compounds (AREA)

Abstract

LA PRESENTE INVENTION CONCERNE DE NOUVEAUX ANALOGUES DE LA 5,6-DIHYDRO-PROSTACYCLINE QUI ONT POUR FORMULE: (CF DESSIN DANS BOPI) (CF DESSIN DANS BOPI) OU L' REPRESENTE (CH)-, Q REPRESENTE HOH,R REPRESENTE, R REPRESENTE -CHET X REPRESENTE TRANS-CHCH-. CES COMPOSES SONT UTILES COMME MEDICAMENTS POUR LES MEMES APPLICATIONS THERAPEUTIQUES QUE CELLES FIGURANT AU BREVET PRINCIPAL.THE PRESENT INVENTION CONCERNS NEW ANALOGUES OF 5,6-DIHYDRO-PROSTACYCLINE WHICH HAVE THE FORMULA: (CF DRAWING IN BOPI) (CF DRAWING IN BOPI) OR THE REPRESENT (CH) -, Q REPRESENTS HOH, R REPRESENTS, R REPRESENTS -CHET X REPRESENTS TRANS-CHCH-. THESE COMPOUNDS ARE USEFUL AS MEDICINAL PRODUCTS FOR THE SAME THERAPEUTIC APPLICATIONS AS THOSE APPEARING IN THE MAIN PATENT.

FR7834072A 1977-12-05 1978-12-04 5,6-DIHYDRO-PROSTACYCLINE ANALOGS AND THEIR PREPARATION Expired FR2410652B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/857,203 US4125713A (en) 1976-06-01 1977-12-05 Certain 5,6-dihydra-prostacyclin analogs

Publications (2)

Publication Number Publication Date
FR2410652A2 true FR2410652A2 (en) 1979-06-29
FR2410652B2 FR2410652B2 (en) 1986-05-23

Family

ID=25325440

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7834072A Expired FR2410652B2 (en) 1977-12-05 1978-12-04 5,6-DIHYDRO-PROSTACYCLINE ANALOGS AND THEIR PREPARATION

Country Status (4)

Country Link
BE (1) BE871209R (en)
FR (1) FR2410652B2 (en)
GB (1) GB2009160B (en)
IE (1) IE48172B1 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE862514A (en) * 1976-12-31 1978-04-14 Erba Carlo Spa BICYCLIC PROSTAGLANDINS AND THEIR PREPARATION PROCESS
DE2803638A1 (en) * 1977-01-31 1978-08-03 Ono Pharmaceutical Co PROSTAGLANDIN ANALOGS

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE862514A (en) * 1976-12-31 1978-04-14 Erba Carlo Spa BICYCLIC PROSTAGLANDINS AND THEIR PREPARATION PROCESS
DE2803638A1 (en) * 1977-01-31 1978-08-03 Ono Pharmaceutical Co PROSTAGLANDIN ANALOGS

Also Published As

Publication number Publication date
GB2009160B (en) 1983-04-27
BE871209R (en) 1979-04-12
IE782403L (en) 1979-06-05
IE48172B1 (en) 1984-10-17
FR2410652B2 (en) 1986-05-23
GB2009160A (en) 1979-06-13

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