FR2410641A1 - Formes racemiques et optiquement actives de (biphenylyl-4)-2 n-(diethylamino alkyl) propionamides et de leurs sels utiles comme agents spasmolytiques et procedes de preparation - Google Patents
Formes racemiques et optiquement actives de (biphenylyl-4)-2 n-(diethylamino alkyl) propionamides et de leurs sels utiles comme agents spasmolytiques et procedes de preparationInfo
- Publication number
- FR2410641A1 FR2410641A1 FR7833889A FR7833889A FR2410641A1 FR 2410641 A1 FR2410641 A1 FR 2410641A1 FR 7833889 A FR7833889 A FR 7833889A FR 7833889 A FR7833889 A FR 7833889A FR 2410641 A1 FR2410641 A1 FR 2410641A1
- Authority
- FR
- France
- Prior art keywords
- propionamides
- biphenylyl
- racemic
- preparation
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT964377A IT1090782B (it) | 1977-11-30 | 1977-11-30 | 2 4 bifenilil 2 dietilamino alchil propionamide suoi sali e procedimenti di fabbricazione relativi |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2410641A1 true FR2410641A1 (fr) | 1979-06-29 |
FR2410641B1 FR2410641B1 (it) | 1983-04-15 |
Family
ID=11132874
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7833889A Granted FR2410641A1 (fr) | 1977-11-30 | 1978-11-30 | Formes racemiques et optiquement actives de (biphenylyl-4)-2 n-(diethylamino alkyl) propionamides et de leurs sels utiles comme agents spasmolytiques et procedes de preparation |
Country Status (9)
Country | Link |
---|---|
JP (1) | JPS5490157A (it) |
BE (1) | BE872403A (it) |
CA (1) | CA1118446A (it) |
CH (1) | CH637370A5 (it) |
DE (1) | DE2851416A1 (it) |
ES (1) | ES475533A1 (it) |
FR (1) | FR2410641A1 (it) |
IT (1) | IT1090782B (it) |
NL (1) | NL7811698A (it) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003029187A1 (en) * | 2001-09-28 | 2003-04-10 | Dompe S.P.A. | Quaternary ammonium salts of omega-aminoalkylamides of r-2-aryl-propionic acids and pharmaceutical compositions containing them |
WO2008017903A1 (en) * | 2006-08-08 | 2008-02-14 | Techfields Biochem Co. Ltd | Positively charged water-soluble prodrugs of aryl- and heteroarylacetic acids with very fast skin penetration rate |
WO2008020270A1 (en) * | 2006-08-15 | 2008-02-21 | Techfields Biochem Co. Ltd | Positively charged water-soluble prodrugs of aryl- and heteroarylpropionic acids with very fast skin penetration rate |
AU2013206218A1 (en) * | 2006-08-15 | 2013-06-27 | Techfields Biochem Co. Ltd | Positively charged water-soluble prodrugs of aryl- and heteroarylpropionic acids with very fast skin penetration rate |
US9371284B2 (en) | 2007-06-04 | 2016-06-21 | Techfields Pharma Co., Ltd. | Pro-drugs of NSAIAS with very high skin and membranes penetration rates and their new medicinal uses |
US9872846B2 (en) | 2006-07-09 | 2018-01-23 | Techfields Pharma Co., Ltd. | High penetration compositions and uses thereof |
US11135153B2 (en) | 2006-07-09 | 2021-10-05 | Techfields Pharma Co., Ltd. | High penetration composition and uses thereof |
US11541029B2 (en) | 2008-12-04 | 2023-01-03 | Techfields Pharma Co., Ltd. | High penetration compositions and their applications |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5940036B2 (ja) * | 2013-10-08 | 2016-06-29 | テックフィールズ バイオケム カンパニー リミテッド | 非常に速い皮膚透過率を有するアリール−及びヘテロアリールプロピオン酸の正荷電水溶性プロドラッグ |
JP6290947B2 (ja) * | 2016-02-05 | 2018-03-07 | テックフィールズ バイオケム カンパニー リミテッド | 非常に速い皮膚透過率を有するアリール−及びヘテロアリールプロピオン酸の正荷電水溶性プロドラッグ |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1584547A (it) * | 1968-06-05 | 1969-12-26 | ||
FR1593024A (it) * | 1968-09-18 | 1970-05-25 | ||
FR2119846A1 (en) * | 1970-12-28 | 1972-08-11 | Choay Sa | N,n-diethylaminoethylamide of para isobutyl phenylacetic - acid - antiinflammatory and analgesic |
FR2370723A1 (fr) * | 1976-11-12 | 1978-06-09 | Upjohn Co | Nouveaux aryl-acylamides n-(2-aminocycloaliphatiques), leur procede de preparation et medicament les contenant |
-
1977
- 1977-11-30 IT IT964377A patent/IT1090782B/it active
-
1978
- 1978-11-28 CH CH1216178A patent/CH637370A5/it not_active IP Right Cessation
- 1978-11-28 DE DE19782851416 patent/DE2851416A1/de active Granted
- 1978-11-29 ES ES475533A patent/ES475533A1/es not_active Expired
- 1978-11-29 NL NL7811698A patent/NL7811698A/xx not_active Application Discontinuation
- 1978-11-30 FR FR7833889A patent/FR2410641A1/fr active Granted
- 1978-11-30 CA CA000317175A patent/CA1118446A/en not_active Expired
- 1978-11-30 JP JP14730778A patent/JPS5490157A/ja active Granted
- 1978-11-30 BE BE192036A patent/BE872403A/xx not_active IP Right Cessation
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1584547A (it) * | 1968-06-05 | 1969-12-26 | ||
FR1593024A (it) * | 1968-09-18 | 1970-05-25 | ||
FR2119846A1 (en) * | 1970-12-28 | 1972-08-11 | Choay Sa | N,n-diethylaminoethylamide of para isobutyl phenylacetic - acid - antiinflammatory and analgesic |
FR2370723A1 (fr) * | 1976-11-12 | 1978-06-09 | Upjohn Co | Nouveaux aryl-acylamides n-(2-aminocycloaliphatiques), leur procede de preparation et medicament les contenant |
Cited By (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7026510B2 (en) | 2001-09-28 | 2006-04-11 | Dompé S.p.A. | Quaternary ammonium salts of omega-aminoalkylamides of r-2-aryl-propionic acids and pharmaceutical compositions containing them |
WO2003029187A1 (en) * | 2001-09-28 | 2003-04-10 | Dompe S.P.A. | Quaternary ammonium salts of omega-aminoalkylamides of r-2-aryl-propionic acids and pharmaceutical compositions containing them |
AU2002338784B2 (en) * | 2001-09-28 | 2008-08-14 | Dompe' Farmaceutici S.P.A. | Quaternary ammonium salts of omega-aminoalkylamides of R-2-aryl-propionic acids and pharmaceutical compositions containing them |
US9872846B2 (en) | 2006-07-09 | 2018-01-23 | Techfields Pharma Co., Ltd. | High penetration compositions and uses thereof |
US11135153B2 (en) | 2006-07-09 | 2021-10-05 | Techfields Pharma Co., Ltd. | High penetration composition and uses thereof |
WO2008017903A1 (en) * | 2006-08-08 | 2008-02-14 | Techfields Biochem Co. Ltd | Positively charged water-soluble prodrugs of aryl- and heteroarylacetic acids with very fast skin penetration rate |
WO2008020270A1 (en) * | 2006-08-15 | 2008-02-21 | Techfields Biochem Co. Ltd | Positively charged water-soluble prodrugs of aryl- and heteroarylpropionic acids with very fast skin penetration rate |
AU2013206218B2 (en) * | 2006-08-15 | 2016-06-30 | Techfields Biochem Co. Ltd | Positively charged water-soluble prodrugs of aryl- and heteroarylpropionic acids with very fast skin penetration rate |
AU2013206218A1 (en) * | 2006-08-15 | 2013-06-27 | Techfields Biochem Co. Ltd | Positively charged water-soluble prodrugs of aryl- and heteroarylpropionic acids with very fast skin penetration rate |
AU2006347391B2 (en) * | 2006-08-15 | 2013-03-07 | Techfields Biochem Co. Ltd | Positively charged water-soluble prodrugs of aryl- and heteroarylpropionic acids with very fast skin penetration rate |
US9371284B2 (en) | 2007-06-04 | 2016-06-21 | Techfields Pharma Co., Ltd. | Pro-drugs of NSAIAS with very high skin and membranes penetration rates and their new medicinal uses |
US10233198B2 (en) | 2007-06-04 | 2019-03-19 | Techfields Pharma Co., Ltd. | Pro-drugs of NSAIAs with very high skin and membranes penetration rates and their new medicinal uses |
US11541029B2 (en) | 2008-12-04 | 2023-01-03 | Techfields Pharma Co., Ltd. | High penetration compositions and their applications |
Also Published As
Publication number | Publication date |
---|---|
JPS5490157A (en) | 1979-07-17 |
JPS631286B2 (it) | 1988-01-12 |
CA1118446A (en) | 1982-02-16 |
NL7811698A (nl) | 1979-06-01 |
IT1090782B (it) | 1985-06-26 |
BE872403A (fr) | 1979-03-16 |
CH637370A5 (en) | 1983-07-29 |
ES475533A1 (es) | 1980-01-16 |
DE2851416A1 (de) | 1979-05-31 |
DE2851416C2 (it) | 1989-02-23 |
FR2410641B1 (it) | 1983-04-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |