FR2409994A1 - Derives de naphtalene et leur application en therapeutique - Google Patents

Derives de naphtalene et leur application en therapeutique

Info

Publication number
FR2409994A1
FR2409994A1 FR7735307A FR7735307A FR2409994A1 FR 2409994 A1 FR2409994 A1 FR 2409994A1 FR 7735307 A FR7735307 A FR 7735307A FR 7735307 A FR7735307 A FR 7735307A FR 2409994 A1 FR2409994 A1 FR 2409994A1
Authority
FR
France
Prior art keywords
alkyl
antiinflammatories
antipyretics
analgesics
heterocyclyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7735307A
Other languages
English (en)
French (fr)
Other versions
FR2409994B1 (de
Inventor
Thomas Andrew Purcell
Braham Shroot
Daniel Jean Marie Galtier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR7735307A priority Critical patent/FR2409994A1/fr
Priority to DE7878400173T priority patent/DE2860314D1/de
Priority to EP78400173A priority patent/EP0002401B1/de
Priority to DK519678A priority patent/DK519678A/da
Priority to US05/962,760 priority patent/US4243665A/en
Priority to ZA00786553A priority patent/ZA786553B/xx
Priority to NZ188982A priority patent/NZ188982A/xx
Priority to AR274539A priority patent/AR225604A1/es
Priority to IT30063/78A priority patent/IT1101422B/it
Priority to IL56021A priority patent/IL56021A/xx
Priority to NO783933A priority patent/NO783933L/no
Priority to ES475299A priority patent/ES475299A1/es
Priority to PT68821A priority patent/PT68821A/pt
Priority to GR57721A priority patent/GR65321B/el
Priority to FI783586A priority patent/FI783586A/fi
Priority to CA316,787A priority patent/CA1101858A/en
Priority to MX10091278U priority patent/MX5009E/es
Priority to AU41884/78A priority patent/AU517219B2/en
Priority to IE2313/78A priority patent/IE47677B1/en
Priority to JP53145934A priority patent/JPS6039273B2/ja
Priority to AT0840578A priority patent/AT366679B/de
Publication of FR2409994A1 publication Critical patent/FR2409994A1/fr
Application granted granted Critical
Publication of FR2409994B1 publication Critical patent/FR2409994B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205—Radicals derived from carbonic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7735307A 1977-11-24 1977-11-24 Derives de naphtalene et leur application en therapeutique Granted FR2409994A1 (fr)

Priority Applications (21)

Application Number Priority Date Filing Date Title
FR7735307A FR2409994A1 (fr) 1977-11-24 1977-11-24 Derives de naphtalene et leur application en therapeutique
DE7878400173T DE2860314D1 (en) 1977-11-24 1978-11-10 Derivatives of naphthalene, process for their preparation and their therapeutic application
EP78400173A EP0002401B1 (de) 1977-11-24 1978-11-10 Naphtalen-Derivate, Verfahren zu deren Herstellung und deren Verwendung in der Therapeutik
US05/962,760 US4243665A (en) 1977-11-24 1978-11-21 2-Heterocyclylalkyl-6-methoxy-naphthalenes
ZA00786553A ZA786553B (en) 1977-11-24 1978-11-21 Naphtalene derivatives
DK519678A DK519678A (da) 1977-11-24 1978-11-21 Fremgangsmaade til fremstilling af naphthalenderivater
ES475299A ES475299A1 (es) 1977-11-24 1978-11-22 Procedimiento para preparar derivados del naftaleno.
IT30063/78A IT1101422B (it) 1977-11-24 1978-11-22 Derivati del naftalene
IL56021A IL56021A (en) 1977-11-24 1978-11-22 2-heterocyclylalklyl-6-methoxy-naphathalenes,their preparation and pharmaceutical compositions containing them
NO783933A NO783933L (no) 1977-11-24 1978-11-22 Fremgangsmaate for fremstilling av naftalenderivater
NZ188982A NZ188982A (en) 1977-11-24 1978-11-22 2-heterocyclylalkyl-6-methoxynaphthalene derivatives and pharmaceutical compositions
AR274539A AR225604A1 (es) 1977-11-24 1978-11-22 Procedimiento para obtener derivados de etil-2-metoxi-6-naftaleno y sus sales
GR57721A GR65321B (en) 1977-11-24 1978-11-23 Method for the preparation of naphthalin derivatives
FI783586A FI783586A (fi) 1977-11-24 1978-11-23 Naftalenderivat
CA316,787A CA1101858A (en) 1977-11-24 1978-11-23 Naphthalene derivatives
MX10091278U MX5009E (es) 1977-11-24 1978-11-23 Procedimiento de preparacion de derivados de naftaleno
AU41884/78A AU517219B2 (en) 1977-11-24 1978-11-23 2-heterocyclyalkyl-6-methoxy-naphthalene
IE2313/78A IE47677B1 (en) 1977-11-24 1978-11-23 Naphthalene derivatives,their preparation and their therapeutic application
PT68821A PT68821A (fr) 1977-11-24 1978-11-23 Procede de preparation de derives de naphtalene
JP53145934A JPS6039273B2 (ja) 1977-11-24 1978-11-24 ナフタレン誘導体およびその製造方法
AT0840578A AT366679B (de) 1977-11-24 1978-11-24 Verfahren zur herstellung von neuen naphthalinderivaten und von deren salzen, racematen und enantiomeren

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7735307A FR2409994A1 (fr) 1977-11-24 1977-11-24 Derives de naphtalene et leur application en therapeutique

Publications (2)

Publication Number Publication Date
FR2409994A1 true FR2409994A1 (fr) 1979-06-22
FR2409994B1 FR2409994B1 (de) 1980-08-22

Family

ID=9197988

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7735307A Granted FR2409994A1 (fr) 1977-11-24 1977-11-24 Derives de naphtalene et leur application en therapeutique

Country Status (3)

Country Link
AT (1) AT366679B (de)
FR (1) FR2409994A1 (de)
ZA (1) ZA786553B (de)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2119077A (en) * 1933-11-24 1938-05-31 Ostro Res Lab Inc Naphthalene derivatives containing a c h n group and process of producing them

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2119077A (en) * 1933-11-24 1938-05-31 Ostro Res Lab Inc Naphthalene derivatives containing a c h n group and process of producing them

Also Published As

Publication number Publication date
AT366679B (de) 1982-04-26
FR2409994B1 (de) 1980-08-22
ZA786553B (en) 1979-10-31
ATA840578A (de) 1981-09-15

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