FR2408588A1 - PROSTAGLANDINE DERIVATIVES - Google Patents

PROSTAGLANDINE DERIVATIVES

Info

Publication number
FR2408588A1
FR2408588A1 FR7822329A FR7822329A FR2408588A1 FR 2408588 A1 FR2408588 A1 FR 2408588A1 FR 7822329 A FR7822329 A FR 7822329A FR 7822329 A FR7822329 A FR 7822329A FR 2408588 A1 FR2408588 A1 FR 2408588A1
Authority
FR
France
Prior art keywords
derivatives
prostaglandine derivatives
prostaglandine
ceto
prostaglandins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7822329A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/819,856 external-priority patent/US4123441A/en
Priority claimed from US05/819,857 external-priority patent/US4158667A/en
Priority claimed from US05/819,940 external-priority patent/US4499293A/en
Priority claimed from US05/819,941 external-priority patent/US4124599A/en
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of FR2408588A1 publication Critical patent/FR2408588A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Furan Compounds (AREA)

Abstract

L'INVENTION EST RELATIVE A DES DERIVES DE PROSTAGLANDINES COMPORTANT UNE CHAINE LATERALE CETO-AMIDEE. CES DERIVES ONT DES ACTIVITES SEMBLABLES A CELLES DES PROSTAGLANDINES MAIS A UN DEGRE PLUS ELEVE.THE INVENTION RELATES TO PROSTAGLANDIN DERIVATIVES INCLUDING A CETO-AMIDE SIDE CHAIN. THESE DERIVATIVES HAVE ACTIVITIES SIMILAR TO THOSE OF PROSTAGLANDINS BUT TO A HIGHER DEGREE.

FR7822329A 1977-07-28 1978-07-27 PROSTAGLANDINE DERIVATIVES Withdrawn FR2408588A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US05/819,856 US4123441A (en) 1976-09-22 1977-07-28 Enlarged-hetero-ring prostacyclin analogs
US05/819,857 US4158667A (en) 1976-02-04 1977-07-28 6-Keto PGF analogs
US05/819,940 US4499293A (en) 1976-09-22 1977-07-28 PGI2 Salts
US05/819,941 US4124599A (en) 1976-09-22 1977-07-28 Enlarged-hetero-ring prostacyclin analogs

Publications (1)

Publication Number Publication Date
FR2408588A1 true FR2408588A1 (en) 1979-06-08

Family

ID=27505860

Family Applications (4)

Application Number Title Priority Date Filing Date
FR7822329A Withdrawn FR2408588A1 (en) 1977-07-28 1978-07-27 PROSTAGLANDINE DERIVATIVES
FR7835804A Granted FR2401921A1 (en) 1977-07-28 1978-12-20 PROSTAGLANDINE DERIVATIVES
FR7835803A Granted FR2401920A1 (en) 1977-07-28 1978-12-20 PROSTAGLANDINE DERIVATIVES
FR7835802A Granted FR2401919A1 (en) 1977-07-28 1978-12-20 PROSTAGLANDINE DERIVATIVES

Family Applications After (3)

Application Number Title Priority Date Filing Date
FR7835804A Granted FR2401921A1 (en) 1977-07-28 1978-12-20 PROSTAGLANDINE DERIVATIVES
FR7835803A Granted FR2401920A1 (en) 1977-07-28 1978-12-20 PROSTAGLANDINE DERIVATIVES
FR7835802A Granted FR2401919A1 (en) 1977-07-28 1978-12-20 PROSTAGLANDINE DERIVATIVES

Country Status (11)

Country Link
JP (1) JPS5427545A (en)
AU (1) AU527238B2 (en)
CH (1) CH639378A5 (en)
DE (1) DE2832372A1 (en)
FR (4) FR2408588A1 (en)
GB (1) GB2001636B (en)
IE (1) IE47284B1 (en)
IL (1) IL55097A0 (en)
IT (1) IT1098350B (en)
NL (1) NL7807543A (en)
SE (3) SE7808040L (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2401919A1 (en) * 1977-07-28 1979-03-30 Upjohn Co PROSTAGLANDINE DERIVATIVES

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU524786B2 (en) * 1977-03-07 1982-10-07 The Upjohn Company Prostacyclins
DE2811950A1 (en) * 1978-03-18 1979-12-13 Hoechst Ag NEW PROSTACYCLIN ANALOGS
US5185374A (en) * 1988-05-11 1993-02-09 K.K. Ueno Seiyaku Oyo Kenkyujo Use of 15-ketoprostaglandin E or F compounds for uterine contraction
BR0212233A (en) * 2001-08-31 2004-10-05 Sucampo Ag Chloride Channel Opener

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2376134A1 (en) * 1976-12-30 1978-07-28 Upjohn Co 6-OXO-PROSTAGLANDIN DERIVATIVES, THEIR PREPARATION PROCESS AND MEDICINAL PRODUCTS CONTAINING

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2351112A1 (en) * 1975-10-21 1977-12-09 Wellcome Found Prostaglandin derivs.
US4035642A (en) * 1976-08-20 1977-07-12 Rohm And Haas Company Gamma counter apparatus
AU524786B2 (en) * 1977-03-07 1982-10-07 The Upjohn Company Prostacyclins
IT1098350B (en) * 1977-07-28 1985-09-07 Upjohn Co PROSTAGLANDINIC DERIVATIVES
IT1088036B (en) * 1977-11-25 1985-06-04 Erba Carlo Spa 15-EPI-PROSTACYCLINE AND ANALOG PROSTACYCLINE

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2376134A1 (en) * 1976-12-30 1978-07-28 Upjohn Co 6-OXO-PROSTAGLANDIN DERIVATIVES, THEIR PREPARATION PROCESS AND MEDICINAL PRODUCTS CONTAINING

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/76 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2401919A1 (en) * 1977-07-28 1979-03-30 Upjohn Co PROSTAGLANDINE DERIVATIVES

Also Published As

Publication number Publication date
SE8304218L (en) 1983-08-01
FR2401919A1 (en) 1979-03-30
SE8304219L (en) 1983-08-01
NL7807543A (en) 1979-01-30
FR2401919B1 (en) 1982-10-22
IE47284B1 (en) 1984-02-08
DE2832372A1 (en) 1979-02-08
CH639378A5 (en) 1983-11-15
FR2401920A1 (en) 1979-03-30
SE8304218D0 (en) 1983-08-01
JPS5427545A (en) 1979-03-01
FR2401920B1 (en) 1982-11-19
GB2001636B (en) 1982-03-17
AU3788278A (en) 1980-01-17
SE7808040L (en) 1979-01-29
FR2401921B1 (en) 1982-10-22
FR2401921A1 (en) 1979-03-30
AU527238B2 (en) 1983-02-24
IT1098350B (en) 1985-09-07
IE781522L (en) 1979-01-28
SE8304219D0 (en) 1983-08-01
IL55097A0 (en) 1978-09-29
IT7825225A0 (en) 1978-06-30
GB2001636A (en) 1979-02-07

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Legal Events

Date Code Title Description
ST Notification of lapse