FR2403345B1 - - Google Patents

Info

Publication number
FR2403345B1
FR2403345B1 FR7826145A FR7826145A FR2403345B1 FR 2403345 B1 FR2403345 B1 FR 2403345B1 FR 7826145 A FR7826145 A FR 7826145A FR 7826145 A FR7826145 A FR 7826145A FR 2403345 B1 FR2403345 B1 FR 2403345B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7826145A
Other versions
FR2403345A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of FR2403345A1 publication Critical patent/FR2403345A1/fr
Application granted granted Critical
Publication of FR2403345B1 publication Critical patent/FR2403345B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/12—Separation; Purification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
FR7826145A 1977-09-19 1978-09-12 Procede d'obtention de l'acide 7- (d-mandelamido)-3- (1-methyl-1,2,3,4-tetrazol-5-yl) thiomethyl-3-cephem-4-carboxylique pur a partir de ses sels Granted FR2403345A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/834,633 US4115644A (en) 1977-09-19 1977-09-19 Process for preparing pure cefamandole from alkali metal and ammonium salts thereof

Publications (2)

Publication Number Publication Date
FR2403345A1 FR2403345A1 (fr) 1979-04-13
FR2403345B1 true FR2403345B1 (fr) 1982-09-10

Family

ID=25267406

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7826145A Granted FR2403345A1 (fr) 1977-09-19 1978-09-12 Procede d'obtention de l'acide 7- (d-mandelamido)-3- (1-methyl-1,2,3,4-tetrazol-5-yl) thiomethyl-3-cephem-4-carboxylique pur a partir de ses sels

Country Status (8)

Country Link
US (1) US4115644A (fr)
JP (1) JPS5455594A (fr)
CA (1) CA1100945A (fr)
DE (1) DE2839670A1 (fr)
ES (1) ES473371A1 (fr)
FR (1) FR2403345A1 (fr)
GB (1) GB2004280B (fr)
IE (1) IE47441B1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101787039B (zh) * 2010-01-26 2012-05-09 陶灵刚 一种高纯度的头孢美唑钠化合物
CN102093392B (zh) 2011-01-28 2013-04-24 海南灵康制药有限公司 一种头孢孟多酯钠的新制法
CN103044453B (zh) * 2013-01-22 2014-07-30 湖北济生医药有限公司 头孢孟多酯钠化合物及其药物组合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds
US3840531A (en) * 1972-03-21 1974-10-08 Lilly Co Eli Process for preparing 7-(alpha-hydroxy-alpha-phenyl)acetamido-3-(1-methyl-1h-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid and derivatives thereof
BE824028A (fr) * 1974-01-23 1975-06-30 Procede pour la purification de cephalosporines comportant un groupe acide carboxylique libre
US4028355A (en) * 1974-01-23 1977-06-07 Smithkline Corporation Cephalosporin purification process
US3947415A (en) * 1974-12-23 1976-03-30 Eli Lilly And Company Cefamandole derivatives
US4029655A (en) * 1975-04-11 1977-06-14 Eli Lilly And Company Method of preparing stable sterile crystalline cephalosporins for parenteral administration

Also Published As

Publication number Publication date
US4115644A (en) 1978-09-19
IE47441B1 (en) 1984-03-21
JPS5455594A (en) 1979-05-02
IE781876L (en) 1979-03-19
GB2004280A (en) 1979-03-28
GB2004280B (en) 1982-03-10
FR2403345A1 (fr) 1979-04-13
JPS6312873B2 (fr) 1988-03-23
CA1100945A (fr) 1981-05-12
DE2839670A1 (de) 1979-03-29
ES473371A1 (es) 1979-11-01

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Legal Events

Date Code Title Description
ST Notification of lapse